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Journal Articles

Factor VIII–antibody structure and membrane binding

Gary E. Gilbert

Blood (2021) 137 (21): 2866–2868.

https://doi.org/10.1182/blood.2021010947

Published: 2021

Journal Articles

Procoagulant activities of skeletal and cardiac muscle myosin depend on contaminating phospholipid

Valerie A. Novakovic, Gary E. Gilbert

Blood (2020) 136 (21): 2469–2472.

https://doi.org/10.1182/blood.2020005930

Published: 2020

Journal Articles

Cryopreserved Platelets Retain Agonist Responsiveness and Support for Factor VIII Function

Valerie Anne Novakovic, MS, Madhumouli Chatterjee, PhD, Gary E Gilbert, MD

Blood (2020) 136 (Supplement 1): 3–4.

https://doi.org/10.1182/blood-2020-143366

Published: 2020

Journal Articles

Platelet-Based Factor VIII Activity Is Inhibited By Anti-C2 Domain Antibodies That Donâ€™t Significantly Inhibit Factor VIII Activity in a Standard Assay

Madhumouli Chatterjee, PhD, Shannon L. Meeks, MD, Valerie Anne Novakovic, MS, John S. Lollar, MD, Gary E Gilbert, MD

Blood (2017) 130 (Supplement 1): 2345.

https://doi.org/10.1182/blood.V130.Suppl_1.2345.2345

Published: 2017

Journal Articles

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Valerie Anne Novakovic, MS, Gary E Gilbert, MD

Blood (2017) 130 (Supplement 1): 1064.

https://doi.org/10.1182/blood.V130.Suppl_1.1064.1064

Published: 2017

Journal Articles

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

Madhumouli Chatterjee, PhD, Shannon L. Meeks, MD, Valerie Anne Novakovic, MS, Pete Lollar, MD, Gary E. Gilbert, MD

Blood (2016) 128 (22): 2567.

https://doi.org/10.1182/blood.V128.22.2567.2567

Published: 2016

Journal Articles

Inhibitory antibodies against factor VIII C1 domain

Gary E. Gilbert

Blood (2016) 128 (16): 2001–2002.

https://doi.org/10.1182/blood-2016-08-727818

Published: 2016

Journal Articles

Platelet Phosphatidylserine Exposure, Survival and Blood Coagulation in Mice Lacking TMEM16F

Gary E. Gilbert, MD, Colin Kretz, PhD, David Ginsburg, MD, Valerie Anne Novakovic, MS

Blood (2015) 126 (23): SCI-32.

https://doi.org/10.1182/blood.V126.23.SCI-32.SCI-32

Published: 2015

Journal Articles

Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine

Gary E. Gilbert, Valerie A. Novakovic, Jialan Shi, Jan Rasmussen, Steven W. Pipe

Blood (2015) 126 (10): 1237–1244.

https://doi.org/10.1182/blood-2015-01-620245

Published: 2015

Includes: Supplemental data

Journal Articles

TMEM16F Deficiency Causes a Strain-Dependent Lethality in Mice and Reduced Phosphatidylserine Exposure on Heterozygous As Well As Homozygous Deficient Mouse Platelets

Colin A Kretz, PhD, Valerie A Novakovic, M.S., Anna Kiseleva, Audrey C.A. Cleuren, PhD, Rami Khoriaty, MD, Elizabeth Adams, PhD, David Ginsburg, MD, Gary E. Gilbert, MD

Blood (2014) 124 (21): 4157.

https://doi.org/10.1182/blood.V124.21.4157.4157

Published: 2014

Journal Articles

Factor VIII inhibitor epitopes and an enigma

Gary E. Gilbert

Blood (2013) 122 (26): 4160–4161.

https://doi.org/10.1182/blood-2013-10-531822

Published: 2013

Journal Articles

Tissue Factor Pathway Inhibitor Modulates Fibrin Deposition In The Brain In a Manner That Is Independent Of Thrombomodulin and Activated Protein C

Susan A. Maroney, DVM, PhD, Paul E. R. Ellery, PhD, Nicholas d Martinez, Mark Zogg, BS, Gary E. Gilbert, M.D., Hartmut Weiler, PhD, Alan E. Mast, MD, PhD

Blood (2013) 122 (21): 2302.

https://doi.org/10.1182/blood.V122.21.2302.2302

Published: 2013

Journal Articles

Thrombin-Stimulated Platelets Have Functional Binding Sites For Factor VIIIa That Are Distinct From Phosphatidylserine

Jialan Shi, PhD, Valerie A Novakovic, M.S., Steven Pipe, Shannon Meeks, M.D., John (Pete) S. Lollar, MD, Stephanie A. Smith, DVM, MS, James H. Morrissey, PhD, Gary E. Gilbert, M.D.

Blood (2013) 122 (21): 3582.

https://doi.org/10.1182/blood.V122.21.3582.3582

Published: 2013

Journal Articles

Lactadherin C2 Domain Exhibits Ptd-L-Ser Specificity and Anticoagulant Properties Distinct From Homologous Factor VIII C2 Domain and Full-Length Lactadherin

Valerie A Novakovic, M.S., Eugene R Gilbert, Jialan Shi, MD, PhD, Gary E. Gilbert, M.D.

Blood (2012) 120 (21): 1105.

https://doi.org/10.1182/blood.V120.21.1105.1105

Published: 2012

Journal Articles

Focal Procoagulant Activity in Space Between TNF-α Treated Endothelial Cells Mediates Focal Fibrin Accumulation and Anti-Streptococcal Function

Junhong Lu, Ph.D., Gary E. Gilbert, M.D.

Blood (2012) 120 (21): 3307.

https://doi.org/10.1182/blood.V120.21.3307.3307

Published: 2012

Journal Articles

Antibody ESH4, Against the Factor VIII C2 Domain, Causes a Remote Change near the Factor IXa Active Site and Inhibition That Is Related to Membrane Composition

Valerie A Novakovic, M.S., Junhong Lu, Ph.D., Gary E. Gilbert, M.D.

Blood (2012) 120 (21): 3355.

https://doi.org/10.1182/blood.V120.21.3355.3355

Published: 2012

Journal Articles

Putative Phospholipid “scramblase” of Scott Syndrome, TMEM16F/Ano6, Mediates Phosphatidylserine Exposure On Filopodia and Cell Margins of Viable Endothelial Cells.

Jialan Shi, MD, PhD, Gary E. Gilbert, M.D.

Blood (2012) 120 (21): 2180.

https://doi.org/10.1182/blood.V120.21.2180.2180

Published: 2012

Journal Articles

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity

Gary E. Gilbert, Valerie A. Novakovic, Randal J. Kaufman, Hongzhi Miao, Steven W. Pipe

Blood (2012) 120 (9): 1923–1932.

https://doi.org/10.1182/blood-2012-01-408245

Published: 2012

Includes: Supplemental data

Journal Articles

Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells

Rui Xie, Chunyan Gao, Wen Li, Jiuxin Zhu, Valerie Novakovic, Jing Wang, Ruishuang Ma, Jin Zhou, Gary E. Gilbert, Jialan Shi

Blood (2012) 119 (10): 2325–2334.

https://doi.org/10.1182/blood-2011-06-362186

Published: 2012

Journal Articles

Stressed Endothelial Cells Compartmentalize the Prothrombinase Complex on Filopodia and Other Convex Membrane Features near the Cell Margin

Jialan Shi, MD, PhD, Dessislava N. Nikova, PhD, Gary E. Gilbert, M.D.

Blood (2011) 118 (21): 372.

https://doi.org/10.1182/blood.V118.21.372.372

Published: 2011

NARROW

Factor VIII–antibody structure and membrane binding

Procoagulant activities of skeletal and cardiac muscle myosin depend on contaminating phospholipid

Cryopreserved Platelets Retain Agonist Responsiveness and Support for Factor VIII Function

Platelet-Based Factor VIII Activity Is Inhibited By Anti-C2 Domain Antibodies That Donâ€™t Significantly Inhibit Factor VIII Activity in a Standard Assay

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Platelet Membranes and Activation Pathway Determine Inhibitory Activity of Anti-Factor VIII C2 Domain Antibodies

Inhibitory antibodies against factor VIII C1 domain

Platelet Phosphatidylserine Exposure, Survival and Blood Coagulation in Mice Lacking TMEM16F

Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine

TMEM16F Deficiency Causes a Strain-Dependent Lethality in Mice and Reduced Phosphatidylserine Exposure on Heterozygous As Well As Homozygous Deficient Mouse Platelets

Factor VIII inhibitor epitopes and an enigma

Tissue Factor Pathway Inhibitor Modulates Fibrin Deposition In The Brain In a Manner That Is Independent Of Thrombomodulin and Activated Protein C

Thrombin-Stimulated Platelets Have Functional Binding Sites For Factor VIIIa That Are Distinct From Phosphatidylserine

Lactadherin C2 Domain Exhibits Ptd-L-Ser Specificity and Anticoagulant Properties Distinct From Homologous Factor VIII C2 Domain and Full-Length Lactadherin

Focal Procoagulant Activity in Space Between TNF-α Treated Endothelial Cells Mediates Focal Fibrin Accumulation and Anti-Streptococcal Function

Antibody ESH4, Against the Factor VIII C2 Domain, Causes a Remote Change near the Factor IXa Active Site and Inhibition That Is Related to Membrane Composition

Putative Phospholipid “scramblase” of Scott Syndrome, TMEM16F/Ano6, Mediates Phosphatidylserine Exposure On Filopodia and Cell Margins of Viable Endothelial Cells.

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity

Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells

Stressed Endothelial Cells Compartmentalize the Prothrombinase Complex on Filopodia and Other Convex Membrane Features near the Cell Margin

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American Society of Hematology

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American Society of Hematology

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