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Gaspard Cretenet
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Journal Articles

Impaired T-Cell Proliferation in Chronic Lymphocytic Leukemia Patients Is Linked to Disturbed Lipid Metabolism and Homeostasis

Chaja F. Jacobs, Fleur S. Peters, Gaspard Cretenet, Noam Zelcer, Helga Simon-Molas, Arnon P. Kater
Journal: Blood
Blood (2023) 142 (Supplement 1): 4624.
https://doi.org/10.1182/blood-2023-188520
Published: 2023
Journal Articles

Multifactorial Basis of T Cell Dysfunction in CLL: Disrupted Mitochondrial Metabolism Induces T Cell Senescence

Nienke B. Goedhart, Helga Simon-Molas, Chiara Montironi, Chaja F. Jacobs, Elena Camerini, Jaco A.C. Van Bruggen, Gaspard Cretenet, Eric Eldering, Fleur S. Peters, Arnon P. Kater
Journal: Blood
Blood (2023) 142 (Supplement 1): 4629.
https://doi.org/10.1182/blood-2023-181624
Published: 2023
Journal Articles

Important Role for Glutamine in Human and Mouse TME Models of CLL ; Towards Development of a PET Tracer As a Novel Diagnostic Tool

Helga Simon-Molas, Chiara Montironi, Gaspard Cretenet, Sjoerd P.P. van Eeden, Rosita Del Prete, Zhenghao Chen, Ingrid A.M. Derks, Mariska Verlaan, Arnon P. Kater, Wissam Beaino, Anna Kabanova, Josée M. Zijlstra, Albert D. Windhorst, Eric Eldering
Journal: Blood
Blood (2023) 142 (Supplement 1): 4622.
https://doi.org/10.1182/blood-2023-174853
Published: 2023
Journal Articles

Evaluation of the T-Cell Metabolic State of Starting Material and Manufactured CAR T Cell Products and Clinical Outcome of CAR T-Cell Therapy for Large B Cell Lymphoma

Chaja F. Jacobs, Helga Simon-Molas, Gaspard Cretenet, Miriam Gutschow, Amy Chattin, Garrett Collett, Lucrezia Colonna, Fleur S. Peters, Arnon P. Kater
Journal: Blood
Blood (2023) 142 (Supplement 1): 3456.
https://doi.org/10.1182/blood-2023-188577
Published: 2023
Journal Articles

Dysfunction of T Cells from Chronic Lymphocytic Leukemia (CLL) Patients Is Linked to Disturbed Lipid and Fatty Acid Homeostasis

Chaja Feige Jacobs, Fleur Peters, Gaspard Cretenet, Eric Eldering, Noam Zelcer, Arnon P. Kater, Helga Simon-Molas
Journal: Blood
Blood (2022) 140 (Supplement 1): 6998–6999.
https://doi.org/10.1182/blood-2022-167217
Published: 2022
Journal Articles

T-Cell Dysfunction in CLL Can be Alleviated By Blocking Sialic Acid-Binding Ig-like Lectin 10 (Siglec-10) Ligation

Jaco A.C. Van Bruggen, Fleur Peters, Joanne M. Rietveld, Gaspard Cretenet, Joseph Melenhorst, Eric Eldering, Arnon P. Kater
Journal: Blood
Blood (2022) 140 (Supplement 1): 12688–12689.
https://doi.org/10.1182/blood-2022-168800
Published: 2022
Journal Articles

Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment

Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D. Smith, Francesco Forconi, Bauke V. Schomakers, Michel van Weeghel, Dean J. Bryant, Jaco A. C. van Bruggen, Fleur S. Peters, Jeffrey C. Rathmell, Gerritje J. W. van der Windt, Arnon P. Kater, Graham Packham, Eric Eldering
Journal: Blood
Blood (2022) 140 (6): 630–643.
https://doi.org/10.1182/blood.2021013990
Published: 2022
Includes: Supplemental data
Journal Articles

Chronic Lymphocytic Leukemia Actively Induces T-Cell Dysfunction By Contact-Dependent Signaling Via CD24 and CD52

Jaco A. C. Van Bruggen, Fleur Peters, Gaspard Cretenet, J. Joseph Melenhorst, Eric Eldering, Arnon P. Kater
Journal: Blood
Blood (2021) 138 (Supplement 1): 3714.
https://doi.org/10.1182/blood-2021-152495
Published: 2021
Journal Articles

Targeting Metabolic Alterations in CLL Microenvironment; Inhibition of Glutamine Import Attenuates Venetoclax Resistance

Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Francesco Forconi, Bauke V Schomakers, Michel van Weeghel, Dean Bryant, Jaco A. C. Van Bruggen, Fleur Peters, Gerritje J. W. van der Windt, Arnon P. Kater, Graham Packham, Eric Eldering
Journal: Blood
Blood (2021) 138 (Supplement 1): 3717.
https://doi.org/10.1182/blood-2021-150236
Published: 2021
Journal Articles

Electron Transport Chain Inhibition Suppresses CD40 Expression and Sensitizes Chronic Lymphocytic Leukaemia Cells to Venetoclax

Zhenghao Chen, Gaspard Cretenet, Valeria Carnazzo, Gerritje J. W. van der Windt, Arnon P. Kater, MDPhD, Eric Eldering, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-142618
Published: 2020
Journal Articles

Effects of Ibrutinib on Metabolic Alterations and Micro-Environmental Signalling in Chronic Lymphocytic Leukaemia

Zhenghao Chen, Gaspard Cretenet, Beatriz Valle-Argos, Francesco Forconi, MD PhD FRCPath, Arnon P. Kater, MDPhD, Graham Packham, PhD, Eric Eldering, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-142839
Published: 2020
Journal Articles

Linking Microenvironmental Signals to Metabolic Switches and Drug Responses in Chronic Lymphocytic Leukemia

Zhenghao Chen, Gaspard Cretenet, Hanneke ter Burg, Gabriela Andrejeva, Jeffrey C Rathmell, Francesco Forconi, MD DM, PhD FRCPath, Gerritje J. W. van der Windt, Arnon P. Kater, Eric Eldering
Journal: Blood
Blood (2019) 134 (Supplement_1): 479.
https://doi.org/10.1182/blood-2019-123005
Published: 2019