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Gene M. Shearer
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Journal Articles

Overactivation of plasmacytoid dendritic cells inhibits antiviral T-cell responses: a model for HIV immunopathogenesis

Adriano Boasso, Caroline M. Royle, Spyridon Doumazos, Veronica N. Aquino, Mara Biasin, Luca Piacentini, Barbara Tavano, Dietmar Fuchs, Francesco Mazzotta, Sergio Lo Caputo, Gene M. Shearer, Mario Clerici, David R. Graham
Journal: Blood
Blood (2011) 118 (19): 5152–5162.
https://doi.org/10.1182/blood-2011-03-344218
Published: 2011
Includes: Supplemental data
Journal Articles

HIV inhibits CD4 + T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells

Adriano Boasso, Jean-Philippe Herbeuval, Andrew W. Hardy, Stephanie A. Anderson, Matthew J. Dolan, Dietmar Fuchs, Gene M. Shearer
Journal: Blood
Blood (2006) 109 (8): 3351–3359.
https://doi.org/10.1182/blood-2006-07-034785
Published: 2006
Includes: Supplemental data
Journal Articles

HIV-1–driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS

Clinical Trials & Observations
Jakob Nilsson, Adriano Boasso, Paula Andrea Velilla, Rui Zhang, Monica Vaccari, Genoveffa Franchini, Gene M. Shearer, Jan Andersson, Claire Chougnet
Journal: Blood
Blood (2006) 108 (12): 3808–3817.
https://doi.org/10.1182/blood-2006-05-021576
Published: 2006
Journal Articles

CTLA-4 blockade decreases TGF-β, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques

Anna Hryniewicz, Adriano Boasso, Yvette Edghill-Smith, Monica Vaccari, Dietmar Fuchs, David Venzon, Janos Nacsa, Michael R. Betts, Wen-Po Tsai, Jean-Michel Heraud, Brigitte Beer, Diann Blanset, Claire Chougnet, Israel Lowy, Gene M. Shearer, Genoveffa Franchini
Journal: Blood
Blood (2006) 108 (12): 3834–3842.
https://doi.org/10.1182/blood-2006-04-010637
Published: 2006
Journal Articles

CD4 + T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon–dependent, TRAIL/DR5-mediated apoptosis

Jean-Philippe Herbeuval, Jean-Charles Grivel, Adriano Boasso, Andrew W. Hardy, Claire Chougnet, Matthew J. Dolan, Hideo Yagita, Jeffrey D. Lifson, Gene M. Shearer
Journal: Blood
Blood (2005) 106 (10): 3524–3531.
https://doi.org/10.1182/blood-2005-03-1243
Published: 2005
Journal Articles

TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1–infected patients and its in vitro production by antigen-presenting cells

Clinical Trials & Observations
Jean-Philippe Herbeuval, Adriano Boasso, Jean-Charles Grivel, Andrew W. Hardy, Stephanie A. Anderson, Matthew J. Dolan, Claire Chougnet, Jeffrey D. Lifson, Gene M. Shearer
Journal: Blood
Blood (2005) 105 (6): 2458–2464.
https://doi.org/10.1182/blood-2004-08-3058
Published: 2005
Journal Articles

Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4 + T cells

Adriano Boasso, Jean-Philippe Herbeuval, Andrew W. Hardy, Christiana Winkler, Gene M. Shearer
Journal: Blood
Blood (2005) 105 (4): 1574–1581.
https://doi.org/10.1182/blood-2004-06-2089
Published: 2005
Journal Articles

B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression

Clinical Trials & Observations
Daria Trabattoni, Marina Saresella, Mara Biasin, Adriano Boasso, Luca Piacentini, Pasquale Ferrante, Haidong Dong, Renato Maserati, Gene M. Shearer, Lieping Chen, Mario Clerici
Journal: Blood
Blood (2003) 101 (7): 2514–2520.
https://doi.org/10.1182/blood-2002-10-3065
Published: 2003
Journal Articles

Alloantigen-induced anti-HIV activity occurs prior to reverse transcription and can be generated by leukocytes from HIV-infected individuals

Ligia A. Pinto, Vesna Blazevic, Gene M. Shearer, Bruce K. Patterson, Matthew J. Dolan
Journal: Blood
Blood (2000) 95 (5): 1875–1876.
https://doi.org/10.1182/blood.V95.5.1875
Published: 2000
Journal Articles

Alloantigen-Stimulated Anti-HIV Activity

Ligia A. Pinto, Sandra Sharpe, David I. Cohen, Gene M. Shearer
Journal: Blood
Blood (1998) 92 (9): 3346–3354.
https://doi.org/10.1182/blood.V92.9.3346
Published: 1998