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Journal Articles

Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias - Implications for the Biology and Therapeutic Targeting of Myeloma

Blood (2019) 134 (Supplement_1): 4407.

https://doi.org/10.1182/blood-2019-130901

Published: 2019

Journal Articles

CRISPR-Based Functional Genomics Studies Reveal Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins: Implications for Novel Therapeutics across Diverse Neoplasias

Blood (2018) 132 (Supplement 1): 1367.

https://doi.org/10.1182/blood-2018-99-116232

Published: 2018

Journal Articles

In Vivo Validation of Essential Genes for Myeloma Cells By CRISPR/Cas9 Studies in a Scaffold-Based System Engineered to Establish a "Humanized" Bone Marrow-like Microenvironment

Ryosuke Shirasaki, MD, Csikos Tamas, PhD, Geoffrey Matthews, PhD, Ricardo De Matos Simoes, PhD, Subhashis Sarkar, PhD, Olga Dashevsky, PhD, Hu Yiguo, PhD, Jeffrey Sorrell, BA, Michal Sheffer, PhD, Eugen Dhimolea, PhD, Megan Bariteau, Brian Glassner, PhD, Aedin Culhane, PhD, Richard WJ Groen, PhD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 4414.

https://doi.org/10.1182/blood.V130.Suppl_1.4414.4414

Published: 2017

Journal Articles

Long-Term Interactions with Bone Marrow Stromal Cells Alter the Molecular Dependencies of Myeloma Cells: Insights from Genomewide CRISPR-Based Functional Genomic Screens

Sara Gandolfi, MD, Olga Dashevsky, PhD, Ricardo De Matos Simoes, PhD, Geoffrey Matthews, PhD, Ryosuke Shirasaki, MD PhD, Michal Sheffer, PhD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 3028.

https://doi.org/10.1182/blood.V130.Suppl_1.3028.3028

Published: 2017

Journal Articles

Functional Genomic Landscape of Epigenetic Dependencies in Myeloma

Ricardo De Matos Simoes, PhD, Geoffrey Matthews, PhD, Daphne Dupere Richer, PhD, Ryosuke Shirasaki, MD, Michal Sheffer, PhD, Olga Dashevsky, PhD, Sara Gandolfi, MD, Eugen Dhimolea, PhD, Brian Glassner, PhD, Richard WJ Groen, PhD, Franciska Vazquez, PhD, Joshua Dempster, PhD, Aviad Tsherniak, PhD, William C. Hahn, MD PhD, Aedin Culhane, PhD, Jonathan D. Licht, MD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 1209.

https://doi.org/10.1182/blood.V130.Suppl_1.1209.1209

Published: 2017

Journal Articles

Integrated Functional Genomic and Pharmacological Characterization of the Kinome of Myeloma Cells

Ricardo De Matos Simoes, PhD, Eugen Dhimolea, PhD, Ryosuke Shirasaki, MD PhD, Sara Gandolfi, MD, Geoffrey Matthews, PhD, Michal Sheffer, PhD, Olga Dashevsky, PhD, Brian Glassner, PhD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 2501.

https://doi.org/10.1182/blood.V130.Suppl_1.2501.2501

Published: 2017

Journal Articles

Integration of Functional Dependencies and Molecular Alterations of Myeloma Cells

Blood (2017) 130 (Supplement 1): 1212.

https://doi.org/10.1182/blood.V130.Suppl_1.1212.1212

Published: 2017

Journal Articles

Systematic Characterization of the "Resistome" of Tumor Cells Against Panels of Small Molecule Inhibitors — Application in the Context of Inhibitors of Transcriptional Cyclin-Dependent Kinases (tCDKs) and Implications for Future "Individualized" Clinical Applications

Ryosuke Shirasaki, MD, Ricardo De Matos Simoes, PhD, Geoffrey Matthews, PhD, Sara Gandolfi, MD, Eugen Dhimolea, PhD, Olga Dashevsky, PhD, Huihui Tang, PhD, Michal Sheffer, PhD, Tinghu Zhang, PhD, Megan Bariteau, Jeffrey Sorrell, BA, Nicholas P Kwiatkowski, PhD, Nathanael Gray, PhD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 3343.

https://doi.org/10.1182/blood.V130.Suppl_1.3343.3343

Published: 2017

NARROW

Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias - Implications for the Biology and Therapeutic Targeting of Myeloma

CRISPR-Based Functional Genomics Studies Reveal Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins: Implications for Novel Therapeutics across Diverse Neoplasias

In Vivo Validation of Essential Genes for Myeloma Cells By CRISPR/Cas9 Studies in a Scaffold-Based System Engineered to Establish a "Humanized" Bone Marrow-like Microenvironment

Long-Term Interactions with Bone Marrow Stromal Cells Alter the Molecular Dependencies of Myeloma Cells: Insights from Genomewide CRISPR-Based Functional Genomic Screens

Functional Genomic Landscape of Epigenetic Dependencies in Myeloma

Integrated Functional Genomic and Pharmacological Characterization of the Kinome of Myeloma Cells

Integration of Functional Dependencies and Molecular Alterations of Myeloma Cells

Systematic Characterization of the "Resistome" of Tumor Cells Against Panels of Small Molecule Inhibitors — Application in the Context of Inhibitors of Transcriptional Cyclin-Dependent Kinases (tCDKs) and Implications for Future "Individualized" Clinical Applications

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American Society of Hematology

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ASH Publications

American Society of Hematology

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