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Journal Articles

Pomalidomide-Dexamethasone in the Management of Heavily Pretreated Multiple Myeloma

Claudio Cerchione, MD PhD, Lucio Catalano, Davide Nappi, Anna Emanuele Pareto, Gerardo Musuraca, MD, Alessandro Lucchesi, MD, Sonia Ronconi, Michela Ceccolini, MD, Delia Cangini, Maria Benedetta Giannini, MD, Valeria Di Battista, Giorgia Simonetti, PhD, Andrea Ghelli Luserna Di Rorà, PhD, Fabrizio Pane, Giovanni Martinelli, MD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-143143

Published: 2020

Journal Articles

The Prolonged Inhibition of Chk1/Chk2 Kinases Enhances Genetic Instability and Compromises the Efficacy of Chemotherapy Against Acute Lymphoblastic Leukemia Cells

Andrea Ghelli Luserna Di Rorà, PhD, Antonella Padella, PhD, Maria Chiara Fontana, PhD, Eugenio Fonzi, PhD, Anna Ferrari, PhD, Enrica Imbrogno, PhD, Martina Ghetti, PhD, Roberta Napolitano, PhD, Maria Teresa Bochicchio, Giovanni Martinelli, MD, Giorgia Simonetti, PhD

Blood (2019) 134 (Supplement_1): 5047.

https://doi.org/10.1182/blood-2019-129964

Published: 2019

Journal Articles

Interferon-γ-Dependent Inflammatory Signature in Acute Myeloid Leukemia Cells Is Able to Shape Stromal and Immune Bone Marrow Microenvironment

Marilena Ciciarello, PhD, Giulia Corradi, PhD, Sabina Sangaletti, PhD, Barbara Bassani, Giorgia Simonetti, PhD, Jayakumar Vadakekolathu, PhD, Giovanni Marconi, Giovanni Martinelli, MD, Mario Paolo Colombo, Sergio Rutella, MDPhDFRCPath, Michele Cavo, Antonio Curti, MD PhD

Blood (2019) 134 (Supplement_1): 1212.

https://doi.org/10.1182/blood-2019-126512

Published: 2019

Journal Articles

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

Blood (2018) 132 (Supplement 1): 2748.

https://doi.org/10.1182/blood-2018-99-118183

Published: 2018

Journal Articles

Up-Regulation of Immune Tolerance Genes in Leukemic Mesenchymal Stromal Cells Is Induced By Acute Myeloid Leukemia Cells through an IFN-Gamma-Dependent Inflammatory Signaling

Marilena Ciciarello, PhD, Giulia Corradi, BS, Giorgia Simonetti, PhD, Giovanni Marconi, Sabina Sangaletti, PhD, Mario Paolo Colombo, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti

Blood (2018) 132 (Supplement 1): 2579.

https://doi.org/10.1182/blood-2018-99-112497

Published: 2018

Journal Articles

Alternative Overexpression of NRF2 or MYC Defines a Subgroup of Poor Prognosis Acute Myeloid Leukemia and Suggests a Novel Therapeutic Strategy By Combined Bromodomain Inhibition and Forced NRF2 Pathway Activation

Giorgia Simonetti, PhD, Samantha Bruno, Carmine Onofrillo, PhD, Cristina Papayannidis, Giovanni Marconi, Michele Cavo, MD, Lorenzo Montanaro, MD PhD, Giovanni Martinelli

Blood (2018) 132 (Supplement 1): 2639.

https://doi.org/10.1182/blood-2018-99-117429

Published: 2018

Journal Articles

Bitter Taste Receptors System Is Expressed and Functional in Both HSCs and Leukemic Cells

Valentina Salvestrini, PhD, Valentina Pensato, Marilena Ciciarello, PhD, Giorgia Simonetti, PhD, Dorian Forte, Simon Mendez-Ferrer, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti

Blood (2018) 132 (Supplement 1): 2560.

https://doi.org/10.1182/blood-2018-99-111806

Published: 2018

Journal Articles

The Malignant Hemopoietic Clone of Triple Negative Patients with Myelofibrosis Shows in Vitro Functional Defects but Is Highly Responsive to the Pro-Survival Signals of Circulating Autologous Microvesicles

Blood (2018) 132 (Supplement 1): 4334.

https://doi.org/10.1182/blood-2018-99-114507

Published: 2018

Journal Articles

A New Gene Expression Profile Signature CRLF2 Overexpression Based Identifies Novel Adult "Triple Negative" Acute Lymphoblastic Leukemia Subgroups

Blood (2018) 132 (Supplement 1): 5284.

https://doi.org/10.1182/blood-2018-99-118062

Published: 2018

Journal Articles

Higher Expression of PALB2 Predict Poor Prognosis in AML Patients and Identifies Potential Targets of Synthetic Lethal Therapies

Antonella Padella, Giovanni Marconi, Giorgia Simonetti, PhD, Andrea Ghelli Luserna Di Rora, Maria Chiara Fontana, MSc, Cristina Papayannidis, Emanuela Ottaviani, Michele Cavo, MD, Simona Soverini, PhD, Giovanni Martinelli

Blood (2018) 132 (Supplement 1): 1507.

https://doi.org/10.1182/blood-2018-99-118210

Published: 2018

Journal Articles

Adult "Triple Negative" ACUTE Lymphoblastic Leukemia Genome Wide Characterization

Blood (2017) 130 (Supplement 1): 2720.

https://doi.org/10.1182/blood.V130.Suppl_1.2720.2720

Published: 2017

Journal Articles

A Three-Genes Signature of Anti-Apoptotic Genes Showed Different Mechanisms in Preventing Apoptosis in Acute Myeloid Leukemia Cells and Could Provide an Useful Model to Establish the Proper BH3-Mimetich Drug or Combination

Jacopo Nanni, MD, Giorgia Simonetti, PhD, Giovanni Marconi, MD, Maria Chiara Fontana, MSc, Samantha Bruno, MSc, Cristina Papayannidis, MD, Antonella Padella, Mariachiara Abbenante, MD, Silvia lo Monaco, Elena Tenti, PhD, Chiara Sartor, Sarah Parisi, MD PhD, Giovanni Martinelli, MD

Blood (2017) 130 (Supplement 1): 4969.

https://doi.org/10.1182/blood.V130.Suppl_1.4969.4969

Published: 2017

Journal Articles

Bromodomain Inhibition Is Effective Against Acute Myeloid Leukemia Cells Under Hypoxia and Induces Genome-Dependent Metabolic Perturbations

Giorgia Simonetti, PhD, Samantha Bruno, MSc, Carmine Onofrillo, PhD, Marco Malferrari, PhD, Cristina Papayannidis, MD PhD, Giovanni Marconi, MD, Michele Cavo, MD, Stefania Rapino, PhD, Lorenzo Montanaro, MD PhD, Giovanni Martinelli, MD

Blood (2017) 130 (Supplement 1): 3936.

https://doi.org/10.1182/blood.V130.Suppl_1.3936.3936

Published: 2017

Journal Articles

Bitter Taste Receptors Are Expressed on Acute Myeloid Leukemia Cells and Their Activation Results in Quiescence Induction and Prevention of Migration

Valentina Salvestrini, PhD, Marilena Ciciarello, Giorgia Simonetti, PhD, Giovanni Martinelli, MD, Michele Cavo, MD, Antonio Curti, MD PhD

Blood (2017) 130 (Supplement 1): 3949.

https://doi.org/10.1182/blood.V130.Suppl_1.3949.3949

Published: 2017

Journal Articles

MHC-I Antigen Presentation Role in Immune Escape of Acute Myeloid Leukemia with High Burden of Genomic Aberration

Giovanni Marconi, MD, Maria Chiara Fontana, MSc, Eugenio Fonzi, PhD, Cristina Papayannidis, MD, Mariachiara Abbenante, MD, Emanuela Ottaviani, Nicoletta Testoni, BSc, Giorgia Simonetti, PhD, Antonella Padella, Chiara Sartor, Carmen Baldazzi, Jacopo Nanni, MD, Luca Bertamini, MD, Andrea Ghelli Luserna Di Rora, Valentina Robustelli, Martina Pazzaglia, Elena Tenti, PhD, Sarah Parisi, MD PhD, Giovanni Martinelli, MD

Blood (2017) 130 (Supplement 1): 3958.

https://doi.org/10.1182/blood.V130.Suppl_1.3958.3958

Published: 2017

Journal Articles

Ex-Vivo Drug Response Profiling for Precision Medicine Approaches in Acute Myeloid Leukemia with the Open Microwell Microfluidic Platform

Laura Rocchi, PhD, Andrea Faenza, PhD, Laura Rambelli, Viviana Guadagnuolo, PhD, Giovanni Marconi, MD, Giorgia Simonetti, PhD, Cristina Papayannidis, MD PhD, Antonella Padella, Nicola Pecorari, Luca Giulianelli, Dario Biscarini, Giovanni Martinelli, MD PhD, Roberto Guerrieri, PhD, Massimo Bocchi, PhD

Blood (2016) 128 (22): 1675.

https://doi.org/10.1182/blood.V128.22.1675.1675

Published: 2016

Journal Articles

Alterations of BRCA1 and PALB2 Define a Novel Class of Complex-Karyotype AML with a Very Bad Prognosis

Blood (2016) 128 (22): 1677.

https://doi.org/10.1182/blood.V128.22.1677.1677

Published: 2016

Journal Articles

Chromothripsis in Acute Myeloid Leukemia Is Strongly Associated with Poor Prognosis and TP53 Alterations

Blood (2016) 128 (22): 1678.

https://doi.org/10.1182/blood.V128.22.1678.1678

Published: 2016

Journal Articles

Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 1679.

https://doi.org/10.1182/blood.V128.22.1679.1679

Published: 2016

Journal Articles

Aggressive Aneuploid Acute Myeloid Leukemia Is Dependent on Alterations of P53, Gain of APC and PLK1 and Loss of RAD50

Blood (2016) 128 (22): 1702.

https://doi.org/10.1182/blood.V128.22.1702.1702

Published: 2016

NARROW

Pomalidomide-Dexamethasone in the Management of Heavily Pretreated Multiple Myeloma

The Prolonged Inhibition of Chk1/Chk2 Kinases Enhances Genetic Instability and Compromises the Efficacy of Chemotherapy Against Acute Lymphoblastic Leukemia Cells

Interferon-γ-Dependent Inflammatory Signature in Acute Myeloid Leukemia Cells Is Able to Shape Stromal and Immune Bone Marrow Microenvironment

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

Up-Regulation of Immune Tolerance Genes in Leukemic Mesenchymal Stromal Cells Is Induced By Acute Myeloid Leukemia Cells through an IFN-Gamma-Dependent Inflammatory Signaling

Alternative Overexpression of NRF2 or MYC Defines a Subgroup of Poor Prognosis Acute Myeloid Leukemia and Suggests a Novel Therapeutic Strategy By Combined Bromodomain Inhibition and Forced NRF2 Pathway Activation

Bitter Taste Receptors System Is Expressed and Functional in Both HSCs and Leukemic Cells

The Malignant Hemopoietic Clone of Triple Negative Patients with Myelofibrosis Shows in Vitro Functional Defects but Is Highly Responsive to the Pro-Survival Signals of Circulating Autologous Microvesicles

A New Gene Expression Profile Signature CRLF2 Overexpression Based Identifies Novel Adult "Triple Negative" Acute Lymphoblastic Leukemia Subgroups

Higher Expression of PALB2 Predict Poor Prognosis in AML Patients and Identifies Potential Targets of Synthetic Lethal Therapies

Adult "Triple Negative" ACUTE Lymphoblastic Leukemia Genome Wide Characterization

A Three-Genes Signature of Anti-Apoptotic Genes Showed Different Mechanisms in Preventing Apoptosis in Acute Myeloid Leukemia Cells and Could Provide an Useful Model to Establish the Proper BH3-Mimetich Drug or Combination

Bromodomain Inhibition Is Effective Against Acute Myeloid Leukemia Cells Under Hypoxia and Induces Genome-Dependent Metabolic Perturbations

Bitter Taste Receptors Are Expressed on Acute Myeloid Leukemia Cells and Their Activation Results in Quiescence Induction and Prevention of Migration

MHC-I Antigen Presentation Role in Immune Escape of Acute Myeloid Leukemia with High Burden of Genomic Aberration

Ex-Vivo Drug Response Profiling for Precision Medicine Approaches in Acute Myeloid Leukemia with the Open Microwell Microfluidic Platform

Alterations of BRCA1 and PALB2 Define a Novel Class of Complex-Karyotype AML with a Very Bad Prognosis

Chromothripsis in Acute Myeloid Leukemia Is Strongly Associated with Poor Prognosis and TP53 Alterations

Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)

Aggressive Aneuploid Acute Myeloid Leukemia Is Dependent on Alterations of P53, Gain of APC and PLK1 and Loss of RAD50

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American Society of Hematology

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American Society of Hematology

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