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Journal Articles

Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16INK4A/CDKN2, MTS2/p15INK4B, p53, and Rb genes in primary lymphoid malignancies

A Hangaishi, S Ogawa, N Imamura, S Miyawaki, Y Miura, N Uike, C Shimazaki, N Emi, K Takeyama, S Hirosawa, N Kamada, Y Kobayashi, Y Takemoto, T Kitani, K Toyama, S Ohtake, Y Yazaki, R Ueda, H Hirai

Blood (1996) 87 (12): 4949–4958.

https://doi.org/10.1182/blood.V87.12.4949.bloodjournal87124949

Published: 1996

Journal Articles

Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice

H Honda, T Fujii, M Takatoku, H Mano, ON Witte, Y Yazaki, H Hirai

Blood (1995) 85 (10): 2853–2861.

https://doi.org/10.1182/blood.V85.10.2853.bloodjournal85102853

Published: 1995

Journal Articles

Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation

K Mitani, Y Kanda, S Ogawa, T Tanaka, J Inazawa, Y Yazaki, H Hirai

Blood (1995) 85 (8): 2017–2024.

https://doi.org/10.1182/blood.V85.8.2017.bloodjournal8582017

Published: 1995

Journal Articles

Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines

T Matsuda, M Takahashi-Tezuka, T Fukada, Y Okuyama, Y Fujitani, S Tsukada, H Mano, H Hirai, ON Witte, T Hirano

Blood (1995) 85 (3): 627–633.

https://doi.org/10.1182/blood.V85.3.627.bloodjournal853627

Published: 1995

Journal Articles

Tec protein-tyrosine kinase is involved in interleukin-3 signaling pathway

H Mano, Y Yamashita, K Sato, Y Yazaki, H Hirai

Blood (1995) 85 (2): 343–350.

https://doi.org/10.1182/blood.V85.2.343.343

Published: 1995

Journal Articles

Characterization of three erythropoietin (Epo)-binding proteins in various human Epo-responsive cell lines and in cells transfected with human Epo-receptor cDNA [see comments]

T Takahashi, S Chiba, N Hirano, Y Yazaki, H Hirai

Blood (1995) 85 (1): 106–114.

https://doi.org/10.1182/blood.V85.1.106.bloodjournal851106

Published: 1995

Journal Articles

Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta

H Honda, J Inazawa, J Nishida, Y Yazaki, H Hirai

Blood (1994) 84 (12): 4186–4194.

https://doi.org/10.1182/blood.V84.12.4186.bloodjournal84124186

Published: 1994

Journal Articles

CD4dull+ hematopoietic progenitor cells in murine bone marrow

M Onishi, K Nagayoshi, K Kitamura, H Hirai, F Takaku, H Nakauchi

Blood (1993) 81 (12): 3217–3225.

https://doi.org/10.1182/blood.V81.12.3217.3217

Published: 1993

Journal Articles

Erythropoietin induces tyrosine phosphorylation and kinase activity of the c-fps/fes proto-oncogene product in human erythropoietin-responsive cells

Y Hanazono, S Chiba, K Sasaki, H Mano, Y Yazaki, H Hirai

Blood (1993) 81 (12): 3193–3196.

https://doi.org/10.1182/blood.V81.12.3193.3193

Published: 1993

Journal Articles

Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS- derived leukemia

K Sugimoto, N Hirano, H Toyoshima, S Chiba, H Mano, F Takaku, Y Yazaki, H Hirai

Blood (1993) 81 (11): 3022–3026.

https://doi.org/10.1182/blood.V81.11.3022.3022

Published: 1993

Journal Articles

Rearrangement of retinoic acid receptor alpha and PML in promyelocytic blast crisis of Ph1 chromosome positive chronic myelocytic leukemia with normal copies of chromosome 15

M Amano, A Togawa, S Tsurugano, Y Soda, A Yuo, F Takaku, S Ogawa, H Hirai, K Yamada

Blood (1993) 81 (9): 2469–2470.

https://doi.org/10.1182/blood.V81.9.2469.2469

Published: 1993

Journal Articles

Treatment of myelodysplastic syndromes with all-trans retinoic acid. Leukemia Study Group of the Ministry of Health and Welfare

R Ohno, T Naoe, M Hirano, M Kobayashi, H Hirai, K Tubaki, H Oh

Blood (1993) 81 (5): 1152–1154.

https://doi.org/10.1182/blood.V81.5.1152.1152

Published: 1993

Journal Articles

Frequent mutations in the p53 gene in human myeloid leukemia cell lines

K Sugimoto, H Toyoshima, R Sakai, K Miyagawa, K Hagiwara, F Ishikawa, F Takaku, Y Yazaki, H Hirai

Blood (1992) 79 (9): 2378–2383.

https://doi.org/10.1182/blood.V79.9.2378.2378

Published: 1992

Journal Articles

Establishment and erythroid differentiation of a cytokine-dependent human leukemic cell line F-36: a parental line requiring granulocyte- macrophage colony-stimulating factor or interleukin-3, and a subline requiring erythropoietin

S Chiba, F Takaku, T Tange, K Shibuya, C Misawa, K Sasaki, K Miyagawa, Y Yazaki, H Hirai

Blood (1991) 78 (9): 2261–2268.

https://doi.org/10.1182/blood.V78.9.2261.2261

Published: 1991

Journal Articles

Stimulatory effects of granulocyte colony-stimulating factor on colony- forming units-spleen (CFU-S) differentiation and pre-CFU-S proliferation in mice

T Tanaka, T Suda, J Suda, T Inoue, Y Hirabayashi, H Hirai, F Takaku, Y Miura

Blood (1991) 77 (12): 2597–2602.

https://doi.org/10.1182/blood.V77.12.2597.2597

Published: 1991

Journal Articles

Mutations of the p53 gene in lymphoid leukemia

K Sugimoto, H Toyoshima, R Sakai, K Miyagawa, K Hagiwara, H Hirai, F Ishikawa, F Takaku

Blood (1991) 77 (6): 1153–1156.

https://doi.org/10.1182/blood.V77.6.1153.1153

Published: 1991

Journal Articles

Ti (WT31)-negative, CD3-positive, large granular lymphocyte leukemia with nonspecific cytotoxicity

K Oshimi, S Hoshino, M Takahashi, M Akahoshi, H Saito, Y Kobayashi, H Hirai, F Takaku, N Yahagi, Y Oshimi

Blood (1988) 71 (4): 923–931.

https://doi.org/10.1182/blood.V71.4.923.923

Published: 1988

Journal Articles

Role of T-cell antigens in the cytolytic activities of large granular lymphocytes (LGLs) in patients with LGL lymphocytosis

K Oshimi, Y Oshimi, M Akahoshi, Y Kobayashi, H Hirai, F Takaku, M Hattori, S Asano, H Kodo, S Nishinarita

Blood (1988) 71 (2): 473–479.

https://doi.org/10.1182/blood.V71.2.473.473

Published: 1988

Journal Articles

Relationship between an activated N-ras oncogene and chromosomal abnormality during leukemic progression from myelodysplastic syndrome

H Hirai, M Okada, H Mizoguchi, H Mano, Y Kobayashi, J Nishida, F Takaku

Blood (1988) 71 (1): 256–258.

https://doi.org/10.1182/blood.V71.1.256.256

Published: 1988

Journal Articles

Transforming genes in human leukemia cells

H Hirai, S Tanaka, M Azuma, Y Anraku, Y Kobayashi, M Fujisawa, T Okabe, A Urabe, F Takaku

Blood (1985) 66 (6): 1371–1378.

https://doi.org/10.1182/blood.V66.6.1371.1371

Published: 1985

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Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16INK4A/CDKN2, MTS2/p15INK4B, p53, and Rb genes in primary lymphoid malignancies

Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice

Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation

Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines

Tec protein-tyrosine kinase is involved in interleukin-3 signaling pathway

Characterization of three erythropoietin (Epo)-binding proteins in various human Epo-responsive cell lines and in cells transfected with human Epo-receptor cDNA [see comments]

Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta

CD4dull+ hematopoietic progenitor cells in murine bone marrow

Erythropoietin induces tyrosine phosphorylation and kinase activity of the c-fps/fes proto-oncogene product in human erythropoietin-responsive cells

Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS- derived leukemia

Rearrangement of retinoic acid receptor alpha and PML in promyelocytic blast crisis of Ph1 chromosome positive chronic myelocytic leukemia with normal copies of chromosome 15

Treatment of myelodysplastic syndromes with all-trans retinoic acid. Leukemia Study Group of the Ministry of Health and Welfare

Frequent mutations in the p53 gene in human myeloid leukemia cell lines

Establishment and erythroid differentiation of a cytokine-dependent human leukemic cell line F-36: a parental line requiring granulocyte- macrophage colony-stimulating factor or interleukin-3, and a subline requiring erythropoietin

Stimulatory effects of granulocyte colony-stimulating factor on colony- forming units-spleen (CFU-S) differentiation and pre-CFU-S proliferation in mice

Mutations of the p53 gene in lymphoid leukemia

Ti (WT31)-negative, CD3-positive, large granular lymphocyte leukemia with nonspecific cytotoxicity

Role of T-cell antigens in the cytolytic activities of large granular lymphocytes (LGLs) in patients with LGL lymphocytosis

Relationship between an activated N-ras oncogene and chromosomal abnormality during leukemic progression from myelodysplastic syndrome

Transforming genes in human leukemia cells

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American Society of Hematology

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American Society of Hematology

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