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Hans De Haard
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Journal Articles

Efficacy and Safety of Intravenous Efgartigimod 10 Mg/Kg in Adult Patients with Primary Immune Thrombocytopenia: Advance, a Phase 3 Clinical Trial in Progress

Adrian C. Newland, Howard A. Liebman, MD, Vickie McDonald, MD, Marc Michel, Yoshitaka Miyakawa, Wim Parys, MD, Hans De Haard, Peter Ulrichts, Marie Godar, Kristof De Beuf, Jaume Ayguasanosa, Catherine M Broome, David J. Kuter, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-141161
Published: 2020
Journal Articles

Phase 2 Study of Efgartigimod, a Novel FcRn Antagonist, in Adult Patients with Primary Immune Thrombocytopenia

Adrian C. Newland, Blanca Sánchez-González, László Rejtő, Miklos Egyed, Nataliya Romanyuk, Marie Godar, Katrien Verschueren, Domenica Gandini, Peter Ulrichts, Jon Beauchamp, Torsten Dreier, E. Sally Ward, Marc Michel, Howard A. Liebman, Hans De Haard, Nicolas Leupin, David J. Kuter
Journal: Blood
Blood (2019) 134 (Supplement_1): 895.
https://doi.org/10.1182/blood-2019-128022
Published: 2019
Journal Articles

Targeting CD70 with Cusatuzumab Eliminates Acute Myeloid Leukemia Stem Cells in Humans

Adrian F Ochsenbein, MD, Thomas Pabst, MD, Sabine Höpner, PhD, Vera Ulrike Bacher, Magdalena Hinterbrandner, Msc, Yara Banz, Rouven Müller, MD, Markus G. Manz, Prof.Dr.MD, Walid Gharib, David Francisco, Rémy Bruggmann, PhD, Luc Van Rompaey, PhD, Mahan Moshir, MSc, Tim Delahaye, MSc, Domenica Gandini, Ellen Erzeel, Anna Hultberg, PhD, Samson Fung, MD, Hans De Haard, Nicolas Leupin, Carsten Riether, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 234.
https://doi.org/10.1182/blood-2019-129916
Published: 2019
Journal Articles

The Combination of the BCL-2 Antagonist Venetoclax with the CD70-Targeting Antibody Cusatuzumab Synergistically Eliminates Primary Human Leukemia Stem Cells

Carsten Riether, PhD, Tanja Chiorazzo, PhD, Amy J. Johnson, PhD, Christina Diane Drenberg, PhD, Khaja Waheeduddin Syed, BPharm, MS, Mahan Moshir, MSc, Anna Hultberg, PhD, Nicolas Leupin, Hans De Haard, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3918.
https://doi.org/10.1182/blood-2019-127464
Published: 2019
Journal Articles

Argx-110 Targeting CD70, in Combination with Azacitidine, Shows Favorable Safety Profile and Promising Anti-Leukemia Activity in Newly Diagnosed AML Patients in an Ongoing Phase 1/2 Clinical Trial

Adrian F Ochsenbein, MD, Carsten Riether, PhD, Ulrike Bacher, Rouven Müller, MD, Sabine Höpner, PhD, Yara Banz, Magdalena Hinterbrandner, Msc, Mario Bargetzi, MD, Markus G. Manz, MD, Luc Van Rompaey, PhD, Mahan Moshir, MSc, Tim Delahaye, MSc, Domenica Gandini, MD PhD, Ellen Erzeel, Anna Hultberg, PhD, Samson Fung, MD, Hans De Haard, PhD, Nicolas Leupin, MD, Thomas Pabst, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2680.
https://doi.org/10.1182/blood-2018-99-118302
Published: 2018
Journal Articles

Argx-110 for Treatment of CD70-Positive Advanced Cutaneous T-Cell Lymphoma in a Phase 1/2 Clinical Trial

Martine Bagot, MD PhD, Marie Maerevoet, MD, Pier Luigi Zinzani, MD, Fritz Offner, MD, Franck Morschhauser, MD, Jean-Marie Michot, MD, Vincent Ribrag, MD, Maxime Battistella, MD PhD, Helene Moins, Angelica Calleri, PhD, Stéphane Dalle, MD PhD, Marie Beylot-Barry, MD PhD, Karen Zwaenepoel, PhD, Koen De Winnie, PhD, Anne Marie-Cardine, PhD, Jean-Michel Cayuela, PhD, Valentina Tabanelli, MD, Giovanna Motta, PhD, Federica Melle, PhD, Anna Hultberg, PhD, Domenica Gandini, MD PhD, Teresa Marafioti, MD, Mahan Moshir, MSc, Tim Delahaye, MSc, Piotr Zabrocki, PhD, Karen Silence, PhD, Luc Van Rompaey, PhD, Armand Bensussan, MD PhD, Hans De Haard, PhD, Patrick Pauwels, MD PhD, Nicolas Leupin, MD, Stefano A. Pileri, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1627.
https://doi.org/10.1182/blood-2018-99-118204
Published: 2018
Journal Articles

Blocking CD70/CD27 Signaling in Combination with Hypomethylating Agents Eradicates Human CD34 + AML Stem and Progenitor Cells in Vitro and In Vivo

Magdalena Hinterbrandner, Msc, Nils Maria Kallen, Ursina Lüthi, Thomas Pabst, MD, Luc Van Rompaey, PhD, Nicolas Leupin, MD, Hans De Haard, PhD, Adrian F Ochsenbein, MD, Carsten Riether, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2652.
https://doi.org/10.1182/blood.V130.Suppl_1.2652.2652
Published: 2017
Journal Articles

Argx-113, a Novel Fc-Based Approach for Antibody-Induced Pathologies Such As Primary Immune Thrombocytopenia

Peter Ulrichts, PhD, Thierry Cousin, MD, Torsten Dreier, PhD, Hans de Haard, PhD, Nicolas Leupin, MD
Journal: Blood
Blood (2016) 128 (22): 4919.
https://doi.org/10.1182/blood.V128.22.4919.4919
Published: 2016