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Journal Articles

The Effect of Supplemental Ascorbate on Defersirox Iron Chelation In the Iron-Loaded Gerbil

Maya Otto-Duessel, MS, Casey Brewer, BS, Aleya Hyderi, BS, Jens Lykkesfeldt, PhD, Ignacio Gonzalez-Gomez, MD, Hanspeter Nick, PhD, John C Wood, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2059.
https://doi.org/10.1182/blood.V116.21.2059.2059
Published: 2010
Journal Articles

Comparison of Two Animal Models for Evaluation of Defersirox Iron Chelation

Maya Otto-Duessel, MS, Casey Brewer, BS, Aleya Hyderi, BS, Jens Lykkesfeldt, PhD, Peter Nielson, PhD, Hanspeter Nick, PhD, John C Wood, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4244.
https://doi.org/10.1182/blood.V116.21.4244.4244
Published: 2010
Journal Articles

Effect of Deferasirox (Exjade ® ) on Labile Plasma Iron Levels in Heavily Iron-Overloaded Patients with Transfusion-Dependent Anemias Enrolled in the Large-Scale, Prospective 1-Year EPIC Trial

John B Porter, Maria Domenica Cappellini, Amal El-Beshlawy, Antonis Kattamis, John F Seymour, Jong Wook Lee, Hanspeter Nick, Dany Habr, Gabor Domokos, Abdel Hmissi, Ali Taher
Journal: Blood
Blood (2008) 112 (11): 3881.
https://doi.org/10.1182/blood.V112.11.3881.3881
Published: 2008
Journal Articles

Iron Chelator ICL670 Inhibits HIV-1 Transcription.

Zufan Debebe, MS, Tatyana Ammosova, Ph.D., Hanspeter Nick, Ph.D., Xiaomei Niu, M.D., Marina Jerebtsova, Ph.D., Patricio Ray, M.D., Victor R. Gordeuk, M.D., Sergei Nekhai, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 3863.
https://doi.org/10.1182/blood.V110.11.3863.3863
Published: 2007
Journal Articles

Susceptibility of Endocrine, Cardiac, and Macrophage Cell Lines to Iron-Mediated Oxidative Damage and the Cytoprotective Effect of the Orally Active Chelator Deferasirox (Exjade®, ICL670).

Hava Glickstein, Hanspeter Nick, Zvi I. Cabantchik
Journal: Blood
Blood (2007) 110 (11): 3825.
https://doi.org/10.1182/blood.V110.11.3825.3825
Published: 2007
Journal Articles

Cytoprotective Effect of ICL670 (Deferasirox) on At20 Endocrine Cells Susceptible to Iron-Evoked Oxidative Damage.

Hava Glickstein, Hanspeter Nick, Zvi Loav Cabantchik
Journal: Blood
Blood (2006) 108 (11): 3825.
https://doi.org/10.1182/blood.V108.11.3825.3825
Published: 2006
Journal Articles

Deferasirox Reduces Iron Overload in a Murine Model of Juvenile Hemochromatosis.

Hanspeter Nick, Peter Allegrini, Lucy Fozard, Ursula Junker, Lisa Rojkjaer, Rishard Salie, Vera Niederkofler, Terrence O’Reilly
Journal: Blood
Blood (2006) 108 (11): 1772.
https://doi.org/10.1182/blood.V108.11.1772.1772
Published: 2006
Journal Articles

Influence of Iron Chelation Therapy on R1 and R2 Calibration Curves in Gerbil Liver and Heart.

John C. Wood, MD, PhD, Michelle I. Aguilar, BS, Maya Otto-Duessel, MS, Hanspeter Nick, PhD, Marvin D. Nelson, MD, Rex Moats, PhD
Journal: Blood
Blood (2006) 108 (11): 1775.
https://doi.org/10.1182/blood.V108.11.1775.1775
Published: 2006
Journal Articles

Twice-Daily Deferasirox Improves Cardiac Iron Chelation in the Gerbil Model of Iron Cardiomyopathy.

Maya Otto-Duessel, MS, Michelle I. Aguilar, BS, Hanspeter Nick, PhD, Rex Moats, PhD, John C. Wood, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 1777.
https://doi.org/10.1182/blood.V108.11.1777.1777
Published: 2006
Journal Articles

Action of chelators in iron-loaded cardiac cells: accessibility to intracellular labile iron and functional consequences

Hava Glickstein, Rinat Ben El, Gabi Link, William Breuer, Abraham M. Konijn, Chaim Hershko, Hanspeter Nick, Z. Ioav Cabantchik
Journal: Blood
Blood (2006) 108 (9): 3195–3203.
https://doi.org/10.1182/blood-2006-05-020867
Published: 2006
Journal Articles

ICL670 Removes Cardiac Iron in a Gerbil Model of Iron Overload.

John C. Wood, MD, PhD, Maya Otto-Duessel, MS, Ignacio Gonzales, MD, Michelle Aguilar, BS, Hanspeter Nick, PhD, Hiro Shimada, MD, Rex Moats, PhD
Journal: Blood
Blood (2005) 106 (11): 2695.
https://doi.org/10.1182/blood.V106.11.2695.2695
Published: 2005
Journal Articles

Comparison of Liver Iron Concentration Measured by the SQUID Biosusceptometers at Hamburg, Torino and Oakland in Patients with Thalassemia and Sickle Cell Disease.

Ellen B. Fung, PhD, RD, Filomena Longo, MD, Roland Fischer, PhD, Rainer Engelhardt, PhD, Zahra Pakbaz, MD, Herbert Optiz, PhD, Robert L. Fagaly, PhD, Hanspeter Nick, PhD, Peter Nielsen, MD, PhD, Elliott Vichinsky, MD, Antonio Piga, MD, Paul Harmatz, MD
Journal: Blood
Blood (2005) 106 (11): 3721.
https://doi.org/10.1182/blood.V106.11.3721.3721
Published: 2005
Journal Articles

Dose Response of Deferoxamine, Deferiprone, and ICL670 Chelation Therapy in a Gerbil Model of Iron Overload.

John C. Wood, MD, PhD, Maya Otto-Duessel, MS, Michelle Aguilar, BS, Hanspeter Nick, PhD, Thomas D. Coates, MD, Moats Rex, PhD
Journal: Blood
Blood (2004) 104 (11): 3621.
https://doi.org/10.1182/blood.V104.11.3621.3621
Published: 2004
Journal Articles

Cardiac MRI (T2,T2*) Predicts Cardiac Iron in the Gerbil Model of Iron Cardiomyopathy.

John C. Wood, MD, PhD, Maya Otto-Duessel, MS, Michelle Aguilar, BS, Hanspeter Nick, PhD, Marvin D. Nelson, MD, Thomas D. Coates, MD, Rex Moats, PhD
Journal: Blood
Blood (2004) 104 (11): 376.
https://doi.org/10.1182/blood.V104.11.376.376
Published: 2004