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Hein Schepers
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Journal Articles

Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT

CME Clinical Trials & Observations
Gerbrig Berger, Leonie I. Kroeze, Theresia N. Koorenhof-Scheele, Aniek O. de Graaf, Kenichi Yoshida, Hiroo Ueno, Yuichi Shiraishi, Satoru Miyano, Eva van den Berg, Hein Schepers, Bert A. van der Reijden, Seishi Ogawa, Edo Vellenga, Joop H. Jansen
Journal: Blood
Blood (2018) 131 (16): 1846–1857.
https://doi.org/10.1182/blood-2017-09-805879
Published: 2018
Includes: Supplemental data
Journal Articles

CITED2 Affects Leukemic Cell Survival By Interfering with p53 Activation

Katharina Mattes, MSc, Gerbrig Berger, BSc, Marjan Geugien, MSc, Joost H.A. Martens, Edo Vellenga, MD PhD, Hein Schepers, PhD
Journal: Blood
Blood (2016) 128 (22): 1542.
https://doi.org/10.1182/blood.V128.22.1542.1542
Published: 2016
Journal Articles

The Role of Cbx Proteins in Human Benign and Malignant Hematopoiesis

Johannes Jung, MD, Hein Schepers, PhD, Seka Lazare, Sonja Buisman, Ellen Weersing, Bertien Dethmers, Karin Klauke, PhD, Lenja Bystrykh, PhD, Gerald De Haan, PhD
Journal: Blood
Blood (2016) 128 (22): 2651.
https://doi.org/10.1182/blood.V128.22.2651.2651
Published: 2016
Journal Articles

CITED2 Cooperates with Low PU.1 and DNMT3A to Maintain Self-Renewal in Hematopoietic Stem Cells

Hein Schepers, PhD, Patrick Korthuis, MSc, Marjan Geugien, MSc, Jennifer Jaques, MSc, Tihomira I. Todorova, MSc, Ulrich Steidl, MD PhD, Jan Jacob Schuringa, PhD, Edo Vellenga, MD PhD
Journal: Blood
Blood (2015) 126 (23): 309.
https://doi.org/10.1182/blood.V126.23.309.309
Published: 2015
Journal Articles

The TAK1-NF-κB axis as therapeutic target for AML

Matthieu Cornelis Johannes Bosman, Hein Schepers, Jennifer Jaques, Annet Zwaantien Brouwers-Vos, Wim Johannes Quax, Jan Jacob Schuringa, Edo Vellenga
Journal: Blood
Blood (2014) 124 (20): 3130–3140.
https://doi.org/10.1182/blood-2014-04-569780
Published: 2014
Includes: Supplemental data
Journal Articles

Decreased PU.1 and Enhanced CITED2 Cooperate To Maintain Self-Renewal In Hematopoietic Stem/Progenitors

Hein Schepers, PhD, Patrick M. Korthuis, BSc, Jan Jacob Schuringa, PhD, Edo Vellenga, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2411.
https://doi.org/10.1182/blood.V122.21.2411.2411
Published: 2013
Journal Articles

CITED2 Modulates Differentiation and Proliferation of Normal and Leukemic Hematopoietic Stem and Progenitor Cells Downstream of PU.1

Hein Schepers, Ph.D, Patrick M. Korthuis, Jan J. Schuringa, PhD, Gerald de Haan, Ph.D, Edo Vellenga, PhD
Journal: Blood
Blood (2011) 118 (21): 922.
https://doi.org/10.1182/blood.V118.21.922.922
Published: 2011
Journal Articles

STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells

Hein Schepers, Djoke van Gosliga, Albertus T. J. Wierenga, Bart J. L. Eggen, Jan Jacob Schuringa, Edo Vellenga
Journal: Blood
Blood (2007) 110 (8): 2880–2888.
https://doi.org/10.1182/blood-2006-08-039073
Published: 2007
Includes: Supplemental data
Journal Articles

Reintroduction of C/EBPα in leukemic CD34 + stem/progenitor cells impairs self-renewal and partially restores myelopoiesis

Hein Schepers, Albertus T. J. Wierenga, Djoke van Gosliga, Bart J. L. Eggen, Edo Vellenga, Jan Jacob Schuringa
Journal: Blood
Blood (2007) 110 (4): 1317–1325.
https://doi.org/10.1182/blood-2006-10-052175
Published: 2007
Journal Articles

STAT5-induced self-renewal and impaired myelopoiesis of human hematopoietic stem/progenitor cells involves down-modulation of C/EBPα

Albertus T. J. Wierenga, Hein Schepers, Malcolm A. S. Moore, Edo Vellenga, Jan Jacob Schuringa
Journal: Blood
Blood (2006) 107 (11): 4326–4333.
https://doi.org/10.1182/blood-2005-11-4608
Published: 2006
Journal Articles

STAT5-Induced Self-Renewal and Impaired Myelopoiesis of Human Hematopoietic Stem/Progenitor Cells Involves Downmodulation of C/EBPα.

Jan Jacob Schuringa, PhD, Bart-Jan Wierenga, BSc, Hein Schepers, Malcolm A.S. Moore, MD/PhD, Edo Vellenga, MD/PhD
Journal: Blood
Blood (2005) 106 (11): 268.
https://doi.org/10.1182/blood.V106.11.268.268
Published: 2005
Journal Articles

HSP27 Protects Malignant Hematopoietic Cells Against VP-16-Induced Apoptosis through Modulation of P38 and C-JUN.

Hein Schepers, MSc, Marjan Geugien, BSc, Marco van der Toorn, BSC, Anton L. Bryantsev, PhD, Harm H. Kampinga, PhD, Edo Vellenga, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 1276.
https://doi.org/10.1182/blood.V104.11.1276.1276
Published: 2004