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Henri M.H. Spronk, PhD
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Journal Articles

Plasma Kallikrein Contributes to Ellagic Acid-Induced Coagulation in the Absence of FXI By Activating Factor IX

Mayken Visser, Rene van Oerle, Hugo ten Cate, MD PhD, Volker Laux, PhD, Stefan Heitmeier, PhD, Henri M.H. Spronk, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1106.
https://doi.org/10.1182/blood-2019-131738
Published: 2019
Journal Articles

Novel Thermostable Inhibitor of Contact Activation Tica Effectively Blocks Contact Activation in Low Tissue Factor Thrombin Generation

Tom Van De Berg, MD, Dennis P.L. Suylen, M.G.L. Christella D. Thomassen, Rene van Oerle, Henri M.H. Spronk, PhD, Rafael Apitz, PhD, H. Coenraad Hemker, MD PhD, Tilman M. Hackeng, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1146.
https://doi.org/10.1182/blood-2019-130875
Published: 2019
Journal Articles

Lipid-Mediated Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample

Pauline van Paridon, BSc, Marina Panova-Noeva, Rene van Oerle, Andreas Schulz, Jürgen Prochaska, Natalie Arnold, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Thomas Münzel, Karl J. Lackner, Tilman M. Hackeng, PhD, Hugo ten Cate, MD PhD, Philipp Wild, Henri M.H. Spronk, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1169.
https://doi.org/10.1182/blood-2018-99-116932
Published: 2018
Journal Articles

Interrogation of the Coagulation Cascade Acute Coronary Syndrome Using Novel Elisa-Based Assays for Single Protease Quantification

Jens Posma, MSc, Rene van Oerle, Diane Fens, Jose govers Riemslag, PhD, Julia Mueller, PhD, Stefan Heitmeier, PhD, Hugo ten Cate, MD PhD, Henri M.H. Spronk, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5013.
https://doi.org/10.1182/blood-2018-99-118353
Published: 2018
Journal Articles

Prothrombin Complex Concentrate in Combination with Fibrinogen Plus Tranexamic Acid Is More Effective Than Mono-Therapy with Prothrombin Complex Concentrate in a Dabigatran Anticoagulation Experimental Polytrauma Model

Oliver Grottke, MD PhD, Markus Honickel, MD, Henri M.H. Spronk, PhD, Hugo ten Cate, Joanne van Ryn, PhD, Rolf Rossaint, MD
Journal: Blood
Blood (2014) 124 (21): 346.
https://doi.org/10.1182/blood.V124.21.346.346
Published: 2014
Journal Articles

Hypercoagulability Promotes Atrial Fibrosis and Fibrillation

Henri M.H. Spronk, PhD, Anne-Margreet de Jong, MD PhD, Hetty C. de Boer, PhD, Alexander Maas, MD, Sander Verheule, PhD, Michiel Rienstra, MD PhD, Pieter W. Kamphuisen, MD PhD, Hugo ten Cate, Harry J Crijns, MD PhD, Isabelle van Gelder, MD PhD, Anton Jan van Zonneveld, PhD, Ullrich Schotten, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4246.
https://doi.org/10.1182/blood.V124.21.4246.4246
Published: 2014
Journal Articles

Ex Vivo Prothrombin Complex Concentrates and a Specific Antidote Are Effective In Reversing Dabigatran-Induced Coagulopathy In Pigs

Joanne van Ryn, PhD, Henri M.H. Spronk, PhD, Rolf Rossaint, MD, Oliver Grottke, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2387.
https://doi.org/10.1182/blood.V122.21.2387.2387
Published: 2013
Journal Articles

Resuscitation With Different Volume Expanders Does Not Influence Coagulation After Antidoting Dabigatran With Its Specific Fab In a Pig Model Of Hemorrhagic Shock

Henri M.H. Spronk, PhD, Joanne van Ryn, PhD, Christian Zentai, Hugo ten Cate, MD, PhD, Rolf Rossaint, MD, Oliver Grottke, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3649.
https://doi.org/10.1182/blood.V122.21.3649.3649
Published: 2013
Journal Articles

Increased FXIa Levels In Patients With a First Acute Myocardial Infarction: The Introduction Of a New Thrombin Generation Based FXIa Assay

Rinske Loeffen, MD, Henri M.H. Spronk, PhD, Rene van Oerle, Harry J Crijns, MD, PhD, Leo Veenstra, MD, Hugo ten Cate
Journal: Blood
Blood (2013) 122 (21): 3618.
https://doi.org/10.1182/blood.V122.21.3618.3618
Published: 2013
Journal Articles

Thrombin Inhibition Prevents Against Severe Atherosclerosis Progression in Prothrombotic Mice

Henri M.H. Spronk, PhD, Julian I Borissoff, Oliver Soehnlein, Rory Koenen, Rene van Oerle, Sylvia Heeneman, Mat J.A.P. Daemen, Charles T Esmon, PhD, Jay L. Degen, PhD, Hartmut Weiler, PhD, Joanne van Ryn, MSc, PhD, Hugo Ten Cate, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 103.
https://doi.org/10.1182/blood.V120.21.103.103
Published: 2012
Journal Articles

Thrombin Generation Capacity of Prothrombin Complex Concentrate in an in Vitro Dilutional Model

Henri M.H. Spronk, PhD, Rolf Rossaint, MD, Henskens M.C. Yvonne, Rene van Oerle, Hugo Ten Cate, MD, PhD, Oliver Grottke, MD
Journal: Blood
Blood (2012) 120 (21): 4380.
https://doi.org/10.1182/blood.V120.21.4380.4380
Published: 2012
Journal Articles

Monitoring Recombinant FVIIa in Hemophilic and Normal Plasma Using a Thrombin Generation Assay

Sarah T.B.G. Loubele, PhD, Henri M.H. Spronk, PhD, Rene van Oerle, Hugo ten Cate, MD PhD, Peter L.A. Giesen, MD PhD
Journal: Blood
Blood (2011) 118 (21): 1207.
https://doi.org/10.1182/blood.V118.21.1207.1207
Published: 2011
Journal Articles

The Contact Activation Coagulation Pathway Is Involved in (Recurrent) Coronary Disease.

Arne W.J.H. Dielis, MD, Jose W.P. Govers-Riemslag, PhD, Mark Winkens, MD, Patricia Wijers-Holys, BSc, Karly Hamulyak, MD PhD, Henri M.H. Spronk, PhD, Johannes Waltenberger, MD PhD, Hugo ten Cate, MD PhD
Journal: Blood
Blood (2007) 110 (11): 129.
https://doi.org/10.1182/blood.V110.11.129.129
Published: 2007
Journal Articles

Particulate Matter Induces Tissue Factor and Attenuates Thrombomodulin in Rat Lungs.

Kim Frederix, Ingeborg M. Kooter, phD, Rene Van Oerle, Karly Hamulyak, MD, phD, Henri M.H. Spronk, phD, Hugo Ten Cate, MD, phD
Journal: Blood
Blood (2006) 108 (11): 1749.
https://doi.org/10.1182/blood.V108.11.1749.1749
Published: 2006