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Karl J. Lackner
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Journal Articles

Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development

Nadine Müller-Calleja, Kristin Grunz, T. Son Nguyen, Jens Posma, Denise Pedrosa, Myriam Meineck, Anne Hollerbach, Johannes Braun, Sabine Muth, Hansjörg Schild, Kathrin Saar, Norbert Hübner, Sriram Krishnaswamy, Jennifer Royce, Luc Teyton, Niels Lemmermann, Julia Weinmann-Menke, Karl J. Lackner, Wolfram Ruf
Journal: Blood
Blood (2024) 143 (12): 1167–1180.
https://doi.org/10.1182/blood.2023022276
Published: 2024
Includes: Supplemental data
Journal Articles

Severe High Molecular Weight Kininogen (HK) Deficiency: Clinical Characteristics, Deficiency-Causing KNG1 Variants in Reported and New Cases, and Estimated Prevalence

Anke Adenaeuer, Stefano Barco, Alice Trinchero, Hanan Nazir, Sarah Krutmann, Chiara Ambaglio, Vincenzo Rocco, Ylenia Pancione, Luigi Tomao, Arlette Ruiz de Saez, Marion Echenagucia, Friederike Häuser, Karl J. Lackner, Heidi Rossmann, Bernhard Lämmle
Journal: Blood
Blood (2021) 138 (Supplement 1): 3200.
https://doi.org/10.1182/blood-2021-152959
Published: 2021
Journal Articles

Protein expression profiling suggests relevance of noncanonical pathways in isolated pulmonary embolism

Clinical Trials & Observations
Vincent Ten Cate, Jürgen H. Prochaska, Andreas Schulz, Thomas Koeck, Alejandro Pallares Robles, Michael Lenz, Lisa Eggebrecht, Steffen Rapp, Marina Panova-Noeva, H. Ardeschir Ghofrani, F. Joachim Meyer, Christine Espinola-Klein, Karl J. Lackner, Matthias Michal, Alexander K. Schuster, Konstantin Strauch, Alexander M. Zink, Volker Laux, Stefan Heitmeier, Stavros V. Konstantinides, Thomas Münzel, Miguel A. Andrade-Navarro, Kirsten Leineweber, Philipp S. Wild
Journal: Blood
Blood (2021) 137 (19): 2681–2693.
https://doi.org/10.1182/blood.2019004571
Published: 2021
Includes: Supplemental data
Journal Articles

Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis

Nadine Müller-Calleja, Anne Hollerbach, Svenja Ritter, Denise G. Pedrosa, Dennis Strand, Claudine Graf, Christoph Reinhardt, Susanne Strand, Philippe Poncelet, John H. Griffin, Karl J. Lackner, Wolfram Ruf
Journal: Blood
Blood (2019) 134 (14): 1119–1131.
https://doi.org/10.1182/blood.2019001530
Published: 2019
Journal Articles

Detection and Differential Diagnosis of Prekallikrein Deficiency: Genetic Study of New Families and Systematic Review of the Literature

Stefano Barco, Stefanie Sollfrank, Alice Trinchero, Luigi Tomao, Barbara Zieger, Johanna A. Kremer Hovinga, MD Prof, Laura Conti, Anke Adenäuer, Erwin Miloni, Karl J. Lackner, Heidi Rossmann, Bernhard Lammle, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2496.
https://doi.org/10.1182/blood-2018-99-116030
Published: 2018
Journal Articles

Lipid-Mediated Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample

Pauline van Paridon, BSc, Marina Panova-Noeva, Rene van Oerle, Andreas Schulz, Jürgen Prochaska, Natalie Arnold, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Thomas Münzel, Karl J. Lackner, Tilman M. Hackeng, PhD, Hugo ten Cate, MD PhD, Philipp Wild, Henri M.H. Spronk, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1169.
https://doi.org/10.1182/blood-2018-99-116932
Published: 2018
Journal Articles

Sex-specific differences in genetic and nongenetic determinants of mean platelet volume: results from the Gutenberg Health Study

Marina Panova-Noeva, Andreas Schulz, M. Iris Hermanns, Vera Grossmann, Evgenia Pefani, Henri M. H. Spronk, Dagmar Laubert-Reh, Harald Binder, Manfred Beutel, Norbert Pfeiffer, Stefan Blankenberg, Tanja Zeller, Thomas Münzel, Karl J. Lackner, Hugo ten Cate, Philipp S. Wild
Journal: Blood
Blood (2016) 127 (2): 251–259.
https://doi.org/10.1182/blood-2015-07-660308
Published: 2016
Includes: Supplemental data
Journal Articles

Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells

Nadine Prinz, Natascha Clemens, Dennis Strand, Inge Pütz, Mareike Lorenz, Andreas Daiber, Pamela Stein, Adriana Degreif, Markus Radsak, Hansjörg Schild, Stefan Bauer, Philipp von Landenberg, Karl J. Lackner
Journal: Blood
Blood (2011) 118 (8): 2322–2332.
https://doi.org/10.1182/blood-2011-01-330639
Published: 2011
Includes: Supplemental data
Journal Articles

Lipoprotein (a) up-regulates the expression of the plasminogen activator inhibitor 2 in human blood monocytes

Christa Buechler, Heidrun Ullrich, Mirko Ritter, Mustafa Porsch-Oezcueruemez, Karl J. Lackner, Stefan Barlage, Sven Olaf Friedrich, Gert M. Kostner, Gerd Schmitz
Journal: Blood
Blood (2001) 97 (4): 981–986.
https://doi.org/10.1182/blood.V97.4.981
Published: 2001