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Journal Articles

Sickle Cell Disease Patients Mount Adequate Humoral but Reduced Cellular Responses to COVID-19 Vaccination

Cilia R. Pothast, Quincy Hofsink, Sabine Haggenburg, Michel Bhoekhan, Nienke J.E. Haverkate, Romy C. Dijkland, Kayleigh van Dijk, Frederik J.H. Falkenburg, Annoek E.C. Broers, Jaap van Doesum, Robert S. van Binnendijk, Gerco den Hartog, Judith A. Burger, Joey H. Bouhuijs, Birgit I. Lissenberg-Witte, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sonja Zweegman, Arnon P. Kater, Kaz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Tim Beaumont, Marit J. van Gils, Abraham Goorhuis, Mette D. Hazenberg, Inger S. Nijhof, Mirjam H.M. Heemskerk, Caroline E. Rutten
Journal: Blood
Blood (2022) 140 (Supplement 1): 1957–1959.
https://doi.org/10.1182/blood-2022-169164
Published: 2022
Journal Articles

Discordant Cellular and Humoral Responses to a 3-Dose COVID-19 mRNA Vaccination Schedule in Patients with Hematologic Malignancies

Cilia R. Pothast, Quincy Hofsink, Sabine Haggenburg, Bhoekhan S. Michel, Nienke J.E. Haverkate, Romy C. Dijkland, Kayleigh Van Dijk, Frederik J.H. Falkenburg, Annoek E.C. Broers, Jaap van Doesum, Robert S. Van Binnendijk, Gerco Den Hartog, Judith A. Burger, Joey H. Bouhuijs, Birgit I. Lissenberg-Witte, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sonja Zweegman, Arnon P. Kater, Kaz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Tim Beaumont, Marit J. Van Gils, Abraham Goorhuis, Mette D. Hazenberg, Inger S. Nijhof, Mirjam H.M. Heemskerk, Caroline E. Rutten
Journal: Blood
Blood (2022) 140 (Supplement 1): 8347–8349.
https://doi.org/10.1182/blood-2022-168991
Published: 2022
Journal Articles

Dendritic Cell Subsets in Bone Marrow and Peripheral Blood of Patients with Myelodysplastic Syndromes Display Numeric and Functional Defects

Nathalie van Leeuwen-Kerkhoff, MD, Theresia M. Westers, PhD, Hetty J Bontkes, PhD, Shahram Kordasti, MD PhD, Ghulam J. Mufti, MD PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4109.
https://doi.org/10.1182/blood.V126.23.4109.4109
Published: 2015
Journal Articles

Apoptotic Blebs From Leukemic Cells as a Source of Tumor Associated Antigen for Monocyte-Derived Dendritic Cell Loading

Jurjen M Ruben, MSc, Hetty J Bontkes, PhD, Theresia M. Westers, PhD, Willemijn van Den Ancker, MSc, Gert J. Ossenkoppele, MD, PhD, Tanja D de Gruijl, PhD, Arjan A. Van de Loosdrecht, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3283.
https://doi.org/10.1182/blood.V116.21.3283.3283
Published: 2010
Journal Articles

Azacitidine Induces A Shift In Th1/Th17 Ratio and FoxP3 Expression In Anti-CD3 Stimulated CD4+ T-Cells; Implications for the Treatment of Myelodysplastic Syndromes

Hetty J Bontkes, Jurjen M Ruben, MSc, Theresia M. Westers, PhD, Gert J. Ossenkoppele, MD, PhD, Arjan A. Van de Loosdrecht, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4026.
https://doi.org/10.1182/blood.V116.21.4026.4026
Published: 2010
Journal Articles

Immunomodulatory Effects of Azacitidine Treatment In High Risk Myelodysplastic Syndrome

Hetty J Bontkes, Canan Alhan, Corien Eeltink, Theresia M. Westers, PhD, Gert J. Ossenkoppele, MD, PhD, Arjan A. Van de Loosdrecht, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1860.
https://doi.org/10.1182/blood.V116.21.1860.1860
Published: 2010
Journal Articles

Expansion of AML Blasts Induces CD14 Expression and Facilitates Leukemic DC Development for Therapeutic Application In AML

Willemijn van den Ancker, Pepijn G.J.T.B. Wijnands, Theresia M. Westers, PhD, Hetty J. Bontkes, PhD, Sandra van Wetering, PhD, Ada M. Kruisbeek, PhD, Gert J. Ossenkoppele, MD, PhD, Tanja D. de Gruijl, PhD., Arjan A. Van de Loosdrecht, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2193.
https://doi.org/10.1182/blood.V116.21.2193.2193
Published: 2010
Journal Articles

Functional PRAME Specific T Cells Can Be Cultured From CD8+ Cells From Healthy Donors but Not From Patients at First CR: Implications for Immunotherapeutic Strategies in AML.

Willemijn van den Ancker, Theresia M Westers, PhD, Hetty J Bontkes, PhD, Dewi Wulandari, Erik Hooijberg, PhD, Anita GM Stam, Saskia JAM Santegoets, PhD, Gert J Ossenkoppele, MD, PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 4139.
https://doi.org/10.1182/blood.V114.22.4139.4139
Published: 2009
Journal Articles

Maturation by Toll Like Receptor Ligand R848 Improves the Uptake of Apoptotic Leukemic Cells by Monocyte Derived Dendritic Cells.

Willemijn van den Ancker, Theresia M Westers, PhD, Hetty J Bontkes, PhD, Tanja D de Gruijl, PhD, Gert J Ossenkoppele, MD, PhD, Arjan A van de Loosdrecht, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2075.
https://doi.org/10.1182/blood.V114.22.2075.2075
Published: 2009
Journal Articles

A Dendritic Cell Based Vaccination Strategy Geared towards Eradication of Leukemic Stem Cells.

Hetty J Bontkes, Jurjen Ruben, Willemijn van den Ancker, Theresia M Westers, PhD, G. Ossenkoppele, MD, PhD, A. A van de Loosdrecht
Journal: Blood
Blood (2009) 114 (22): 2046.
https://doi.org/10.1182/blood.V114.22.2046.2046
Published: 2009
Journal Articles

Comparative Analysis of CD8 + t Cell Priming Efficiencies against a Panel of Leukemia-Associated HLA-A2 Restricted Epitopes Identifies PRAME as a Possible Vaccination Target in AML

Willemijn van den Ancker, Theresia M Westers, PhD, Hetty J Bontkes, PhD, Erik Hooijberg, PhD, Anita GM Stam, Saskia JAM Santegoets, PhD, Gert J Ossenkoppele, MD, PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 5441.
https://doi.org/10.1182/blood.V112.11.5441.5441
Published: 2008