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Journal Articles

Insertion of the 1.2kb Chicken β-Globin 5′HS4 Insulator Element in the LTR Inhibits HIV-1 Vector Mediated Transduction at the Early Infection Step.

Hideki Hanawa, MD, PhD, Takashi Shimada, MD, PhD

Blood (2007) 110 (11): 5137.

https://doi.org/10.1182/blood.V110.11.5137.5137

Published: 2007

Journal Articles

Long-Term Polyclonal and Stable Gene Transfer into Rhesus Repopulating Hematopoietic Stem Cells Using a Simian Immunodeficiency Virus-Based Lentiviral Vector System.

Yoo-Jin Kim, MD, Nadia L. Hussein, Peiman Hematti, MD, Bum-Kee Hong, MD, Boris Calmels, PhD, Robert E. Donahue, DVM, Hideki Hanawa, MD, Arthur W. Nienhuis, MD, Cynthia E. Dunbar, MD

Blood (2006) 108 (11): 3259.

https://doi.org/10.1182/blood.V108.11.3259.3259

Published: 2006

Journal Articles

MLL-AF4 and FLT3 Activation Synergize To Induce Multi Step Leukemogenesis.

Hiroki Yamaguchi, MD, PhD, Koiti Inokuchi, MD.PhD., Hideki Hanawa, MD.PhD., Kazuhiro Sawaguchi, Yoshio Mitamura, Naoya Uchida, MD., Mituharu Inami, MD., Takashi Shimada, MD.PhD., Kazuo Dan, MD.PhD.

Blood (2006) 108 (11): 4321.

https://doi.org/10.1182/blood.V108.11.4321.4321

Published: 2006

Journal Articles

Leukemogenesis of the b2a2 Type p210 BCR/ABL in a Bone Marrow Transplantation Mouse Model Using a Lentivirus Vector.

Naoya Uchida, MD, Hideki Hanawa, MD, PhD, Koiti Inokuchi, MD, PhD, Kazuo Dan, MD, PhD, Takashi Shimada, MD, PhD

Blood (2005) 106 (11): 2875.

https://doi.org/10.1182/blood.V106.11.2875.2875

Published: 2005

Journal Articles

Comparison of Stem Cells Harvested from Adipose Tissue and Bone Marrow.

Rei Ogawa, MD, PhD, Juri Fujimura, MD, Hideki Hanawa, MD, PhD, Yukihiko Hirai, MD, PhD, Toshiyuki Kurai, MD, Hiroshi Mizuno, MD, PhD, Hiko Hyakusoku, MD, PhD, Takashi Shimada, MD, PhD

Blood (2005) 106 (11): 4221.

https://doi.org/10.1182/blood.V106.11.4221.4221

Published: 2005

Journal Articles

Development of an In Vivo Exon Trapping Vector System To Detect Insertional Gene Activation by Lentiviral Vector.

Hideki Hanawa, MD, PhD, Takashi Shimada, MD, PhD

Blood (2005) 106 (11): 3059.

https://doi.org/10.1182/blood.V106.11.3059.3059

Published: 2005

Journal Articles

Developing Lentiviral Vectors for Gene Therapy of Wiskott-Aldrich Syndrome.

Marguerite V. Evans-Galea, PhD, Matthew M. Wielgosz, PhD, Ted S. Strom, MD/PhD, Hideki Hanawa, MD/PhD, John M. Cunningham, MD, Arthur W. Nienhuis, MD

Blood (2004) 104 (11): 3170.

https://doi.org/10.1182/blood.V104.11.3170.3170

Published: 2004

Journal Articles

Assessment of Changes in Gene Expression Caused by Insertions of a Globin Lentiviral Vector Containing Globin Regulatory Elements or a Lentiviral Vector Containing Retroviral LTR Elements.

Phillip W. Hargrove, M.S., Steven Kepes, M.S., Hideki Hanawa, M.D., Ph.D., Cheng Cheng, Ph.D., Geoff Neale, Ph.D., Arthur W. Nienhuis, M.D., Derek A. Persons, M.D., Ph.D.

Blood (2004) 104 (11): 497.

https://doi.org/10.1182/blood.V104.11.497.497

Published: 2004

Journal Articles

Diminished Mobilization of Self-Inactivating (SIN) Lentiviral Vectors Containing Globin Regulatory Elements Compared to Those Containing a Retroviral Long Terminal Repeat.

Hideki Hanawa, MD, PhD, Derek A. Persons, MD, PhD, Takashi Shimada, MD3, Arthur W. Nienhuis, MD4

Blood (2004) 104 (11): 5271.

https://doi.org/10.1182/blood.V104.11.5271.5271

Published: 2004

Journal Articles

Extended β-globin locus control region elements promote consistent therapeutic expression of a γ-globin lentiviral vector in murine β-thalassemia

Hideki Hanawa, Phillip W. Hargrove, Steven Kepes, Deo K. Srivastava, Arthur W. Nienhuis, Derek A. Persons

Blood (2004) 104 (8): 2281–2290.

https://doi.org/10.1182/blood-2004-03-0863

Published: 2004

Journal Articles

Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus–based lentiviral vector system

Hideki Hanawa, Peiman Hematti, Keyvan Keyvanfar, Mark E. Metzger, Allen Krouse, Robert E. Donahue, Steve Kepes, John Gray, Cynthia E. Dunbar, Derek A. Persons, Arthur W. Nienhuis

Blood (2004) 103 (11): 4062–4069.

https://doi.org/10.1182/blood-2004-01-0045

Published: 2004

Journal Articles

Successful treatment of murine β-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells

Derek A. Persons, Esther R. Allay, Nobukuni Sawai, Phillip W. Hargrove, Thomas P. Brent, Hideki Hanawa, Arthur W. Nienhuis, Brian P. Sorrentino

Blood (2003) 102 (2): 506–513.

https://doi.org/10.1182/blood-2003-03-0677

Published: 2003

Journal Articles

The degree of phenotypic correction of murine β-thalassemia intermedia following lentiviral-mediated transfer of a human γ-globin gene is influenced by chromosomal position effects and vector copy number

Derek A. Persons, Phillip W. Hargrove, Esther R. Allay, Hideki Hanawa, Arthur W. Nienhuis

Blood (2003) 101 (6): 2175–2183.

https://doi.org/10.1182/blood-2002-07-2211

Published: 2003

Journal Articles

Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques

Amit C. Nathwani, Andrew M. Davidoff, Hideki Hanawa, Yunyu Hu, Fredric A. Hoffer, Alexander Nikanorov, Clive Slaughter, Catherine Y. C. Ng, Junfang Zhou, Jay N. Lozier, Timothy D. Mandrell, Elio F. Vanin, Arthur W. Nienhuis

Blood (2002) 100 (5): 1662–1669.

https://doi.org/10.1182/blood-2002-02-0589

Published: 2002

Journal Articles

Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA

Amit C. Nathwani, Andrew Davidoff, Hideki Hanawa, Jun-Fang Zhou, Elio F. Vanin, Arthur W. Nienhuis

Blood (2001) 97 (5): 1258–1265.

https://doi.org/10.1182/blood.V97.5.1258

Published: 2001

NARROW

Insertion of the 1.2kb Chicken β-Globin 5′HS4 Insulator Element in the LTR Inhibits HIV-1 Vector Mediated Transduction at the Early Infection Step.

Long-Term Polyclonal and Stable Gene Transfer into Rhesus Repopulating Hematopoietic Stem Cells Using a Simian Immunodeficiency Virus-Based Lentiviral Vector System.

MLL-AF4 and FLT3 Activation Synergize To Induce Multi Step Leukemogenesis.

Leukemogenesis of the b2a2 Type p210 BCR/ABL in a Bone Marrow Transplantation Mouse Model Using a Lentivirus Vector.

Comparison of Stem Cells Harvested from Adipose Tissue and Bone Marrow.

Development of an In Vivo Exon Trapping Vector System To Detect Insertional Gene Activation by Lentiviral Vector.

Developing Lentiviral Vectors for Gene Therapy of Wiskott-Aldrich Syndrome.

Assessment of Changes in Gene Expression Caused by Insertions of a Globin Lentiviral Vector Containing Globin Regulatory Elements or a Lentiviral Vector Containing Retroviral LTR Elements.

Diminished Mobilization of Self-Inactivating (SIN) Lentiviral Vectors Containing Globin Regulatory Elements Compared to Those Containing a Retroviral Long Terminal Repeat.

Extended β-globin locus control region elements promote consistent therapeutic expression of a γ-globin lentiviral vector in murine β-thalassemia

Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus–based lentiviral vector system

Successful treatment of murine β-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells

The degree of phenotypic correction of murine β-thalassemia intermedia following lentiviral-mediated transfer of a human γ-globin gene is influenced by chromosomal position effects and vector copy number

Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques

Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA

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American Society of Hematology

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American Society of Hematology

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