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Journal Articles

Etoposide, Cytarabine and Mitoxantrone- or Fludarabine, Cytarabine and Granulocyte Colony-Stimulating Factor-Based Intensive Reinduction Chemotherapy Is Recommended for Children with Relapsed Acute Myeloid Leukemia: The Results from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05R Study

Hiroshi Moritake, MD PhD, Shiro Tanaka, PhD, Takako Miyamura, MD PhD, Hideki Nakayama, MD, Norio Shiba, MD PhD, Akira Shimada, MDPhD, Kiminori Terui, MD PhD, Yuki Yuza, MD PhD, Katsuyoshi Koh, MD, Hiroaki Goto, MD, PhD, Harumi Kakuda, MD PhD, Akiko M Saito, MD PhD, Daisuke Hasegawa, MD PhD, Shotaro Iwamoto, MD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Daisuke Tomizawa, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6.
https://doi.org/10.1182/blood-2020-133272
Published: 2020
Journal Articles

Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity

Akira Nishimura, MD, Kazuaki Yokoyama, MD PhD, Chika Yamagishi, MD, Toshihiko Imamura, MD PhD, Takuya Naruto, MD PhD, Tomohiro Morio, MD PhD, Yukie Tanaka, PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Naoko Higuchi, MD, Akiko Takada, MD, Haruna Okuno, MD, Shoji Saito, MD PhD, Shuhei Karakawa, MD PhD, Shogo Kobayashi, MD, Daisuke Hasegawa, MD PhD, Hiroyuki Fujisaki, MD PhD, Daiichiro Hasegawa, MD PhD, Kazutoshi Koike, MD PhD, Takashi Koike, MD, Shinya Rai, MD PhD, Katsutsugu Umeda, MD PhD, Hideki Sano, MD, Yujin Sekinaka, MD PhD, Atsushi Ogawa, MD PhD, Akitoshi Kinoshita, MD PhD, Norio Shiba, MD PhD, Mizuka Miki, MD, Fumihiko Kimura, MD PhD, Hideki Nakayama, MD, Yozo Nakazawa, MD PhD, Takashi Taga, MD PhD, Tomohiko Taki, MD PhD, Souichi Adachi, MD PhD, Atsushi Manabe, MD PhD, Katsuyoshi Koh, MD, Yasushi Ishida, MD PhD, Arinobu Tojo, MD PhD, Masatoshi Takagi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-139312
Published: 2020
Journal Articles

Post-Induction Minimal Residual Disease Measured By Flow Cytometry and Deep Sequencing of Mutant GATA1 Are Both Significant Prognostic Factors for Children with Myeloid Leukemia and Down Syndrome: A Nationwide Prospective Study of the Japanese Pediatric Leukemia/Lymphoma Study Group

Takashi Taga, MD PhD, Shiro Tanaka, PhD, Kiminori Terui, MD PhD, Shotaro Iwamoto, MD, Hidefumi Hiramatsu, MD PhD, Takako Miyamura, MD PhD, Yoshiko Hashii, MD PhD, Daisuke Hasegawa, MD PhD, Hiroshi Moritake, MD PhD, Hideki Nakayama, MD, Hiroyuki Takahashi, MD PhD, Akira Shimada, MD PhD, Tomohiko Taki, MD PhD, Tsutomu Toki, PhD, Etsuro Ito, MD PhD, Katsuyoshi Koh, MD, Daiichiro Hasegawa, MD PhD, Asahito Hama, MD PhD, Akiko M Saito, MD PhD, Souichi Adachi, MD PhD, Daisuke Tomizawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3848.
https://doi.org/10.1182/blood-2019-123302
Published: 2019
Journal Articles

Clinical Feature and Genetic Alterations in Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia and Myeloid/NK Cell Acute Leukemia

Akira Nishimura, MD, Kazuaki Yokoyama, MD PhD, Chika Yamagishi, MD, Takuya Naruto, MD PhD, Tomohiro Morio, MD PhD, Akinori Kanai, PhD, Hirotaka Matsui, MD PhD, Naoko Higuchi, MD, Akiko Takada, MD, Haruna Okuno, MD, Shoji Saito, MD, Shuhei Karakawa, MD, Shogo Kobayashi, MD, Hideki Sano, MD, Takashi Koike, MD, Daisuke Hasegawa, MD PhD, Hiroyuki Fujisaki, MD, PhD, Daiichiro Hasegawa, MD PhD, Kazutoshi Koike, MD, Atsushi Ogawa, MD PhD, Akitoshi Kinoshita, MD PhD, Norio Shiba, MD PhD, Mizuka Miki, MD, Hideki Nakayama, MD, Yozo Nakazawa, MD, PhD, Toshihiko Imamura, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Katsuyoshi Koh, MD, Atsushi Manabe, MD PhD, Tomohiko Taki, MD PhD, Yasushi Ishida, MD PhD, Arinobu Tojo, MD PhD, Masatoshi Takagi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2824.
https://doi.org/10.1182/blood-2018-99-118627
Published: 2018
Journal Articles

Effectiveness of Supportive Care Measurements to Reduce Infections during Induction for Children with Acute Myeloid Leukemia: A Report from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG)

Daiichiro Hasegawa, MD PhD, Takako Miyamura, MD PhD, Kozo Nagai, MD, Kazuko Kudo, MD PhD, Tawa Akio, MD PhD, Hirozumi Sano, MD, Keitaro Fukushima, MD, Shotaro Iwamoto, MD, Akitoshi Kinoshita, MD PhD, Hiroyuki Takahashi, Kiminori Terui, MD PhD, Hideki Nakayama, MD, Yuki Arakawa, MD, Kentaro Nakashima, MD, Shohei Yamamoto, MD PhD, Akiko Moriya Saito, MD PhD, Keizo Horibe, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2588.
https://doi.org/10.1182/blood.V130.Suppl_1.2588.2588
Published: 2017
Journal Articles

Clinical and Biological Features of Pediatric Acute Myeloid Leukemia with Primary Induction Failure in the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05 Study

Takako Miyamura, MD, PhD, Shiro Tanaka, PhD, Hideki Nakayama, MD PhD, Hiroshi Moritake, MD PhD, Daisuke Tomizawa, MD PhD, Akiko M. Saito, MD PhD, Akio Tawa, MD PhD, Shotaro Iwamoto, MD PhD, Akira Shimada, MD PhD, Kiminori Terui, MD PhD, Tsuyoshi Morimoto, Yasuhide Hayashi, MD PhD, Keizo Horibe, MD PhD, Shuki Mizutani, MD, PhD, Takashi Taga, MD PhD, Souichi Adachi, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 1610.
https://doi.org/10.1182/blood.V128.22.1610.1610
Published: 2016
Journal Articles

The Outcome of Relapsed Childhood Core Binding Factor Acute Myeloid Leukemia: A Report from the JPLSG AML-05R Study

Hiroshi Moritake, MD PhD, Shiro Tanaka, PhD, Hideki Nakayama, MD PhD, Takako Miyamura, MD PhD, Shotaro Iwamoto, MD PhD, Akira Shimada, MD PhD, Kiminori Terui, MDPhD, Akiko M. Saito, Norio Shiba, MD PhD, Yasuhide Hayashi, MD PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Hiroaki Goto, MD PhD, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Shuki Mizutani, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2516.
https://doi.org/10.1182/blood.V126.23.2516.2516
Published: 2015
Journal Articles

Prognostic Significance of CXCR4 Overexpression in Pediatric Acute Myeloid Leukemia with Low-Risk: A Report from the Japanese Pediatric Leukemia/Lymphoma Study Group

Hidemasa Matsuo, MS, Naomi Nakamura, MS, Daisuke Tomizawa, MD PhD, Akiko M. Saito, Nobutaka Kiyokawa, MDPhD, Keizo Horibe, MD PhD, Yoko Nishinaka-Arai, PhD, Mayu Tokumasu, MD, Hiroshi Itoh, MS, Yasuhiko Kamikubo, MD PhD, Hideki Nakayama, MD PhD, Akitoshi Kinoshita, MD PhD, Takashi Taga, MD PhD, Akio Tawa, MD PhD, Tomohiko Taki, MD PhD, Shiro Tanaka, PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3814.
https://doi.org/10.1182/blood.V126.23.3814.3814
Published: 2015
Journal Articles

Risk-Oriented Therapy for Myeloid Leukemia of Down Syndrome: A Nationwide Prospective Study By the Japanese Pediatric Leukemia / Lymphoma Study Group (JPLSG)

Takashi Taga, MD PhD, Tomoyuki Watanabe, Kazuko Kudo, MDPhD, Daisuke Tomizawa, MD PhD, Kiminori Terui, MD PhD, Hiroshi Moritake, MD PhD, Akitoshi Kinoshita, MD PhD, Shotaro Iwamoto, MD PhD, Hideki Nakayama, MD PhD, Hiroyuki Takahashi, MD PhD, Akira Shimada, MD PhD, Tomohiko Taki, MD PhD, Tsutomu Toki, PhD, Etsuro Ito, MD PhD, Hiroaki Goto, MD, PhD, Katsuyoshi Koh, MD, Akiko M. Saito, MD PhD, Keizo Horibe, MD PhD, Tatsutoshi Nakahata, MD PhD, Akio Tawa, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3668.
https://doi.org/10.1182/blood.V124.21.3668.3668
Published: 2014
Journal Articles

Outcome of Adolescent and Young Adults with Acute Myeloid Leukemia Treated with Pediatric Protocols: A Report from the 3 Japanese Cooperative Studies

Daisuke Tomizawa, MD PhD, Tomoyuki Watanabe, PhD, Ryoji Hanada, MD, Keizo Horibe, MD PhD, Yasuo Horikoshi, MD, Shotaro Iwamoto, MD PhD, Akitoshi Kinoshita, MD PhD, Hiroshi Moritake, MD PhD, Hideki Nakayama, MD PhD, Akira Shimada, MD PhD, Takashi Taga, MD PhD, Hiroyuki Takahashi, MD PhD, Akio Tawa, MD PhD, Kiminori Terui, MD PhD, Hiroki Hori, MD, Yoshifumi Kawano, MD PhD, Atsushi Kikuta, MD PhD, Atsushi Manabe, MD PhD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 374.
https://doi.org/10.1182/blood.V124.21.374.374
Published: 2014
Journal Articles

High Event-Free Survival Rate with Minimum-Dose-Anthracycline Treatment in Childhood Acute Promyelocytic Leukemia: A Nationwide Prospective Study By the Japanese Pediatric Leukemia / Lymphoma Study Group (JPLSG)

Hiroyuki Takahashi, MD PhD, Tomoyuki Watanabe, PhD, Akitoshi Kinoshita, MD PhD, Yuki Yuza, MD PhD, Hiroshi Moritake, MD PhD, Kiminori Terui, MD PhD, Shotaro Iwamoto, MD PhD, Hideki Nakayama, MD PhD, Akira Shimada, MD PhD, Kazuko Kudo, MDPhD, Tomohiko Taki, MD PhD, Miharu Yabe, MD PhD, Hiromichi Matsushita, MD PhD, Yuka Yamashita, PhD, Kazutoshi Koike, MD, Atsushi Ogawa, MD, Yoshiyuki Kosaka, MD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Akiko M. Saito, MD PhD, Keizo Horibe, MD, Tatsutoshi Nakahata, MD PhD, Hayato Miyachi, MD PhD, Akio Tawa, MD PhD, Souichi Adachi, MDPhD
Journal: Blood
Blood (2014) 124 (21): 956.
https://doi.org/10.1182/blood.V124.21.956.956
Published: 2014
Journal Articles

Poor Prognosis With Different Induction Rate Was Observed In Children With Acute Myeloid Leukemia and FLT3 -ITD According To The ITD/WT Allelic Ratio: A Result From The Japanese Pediatric Leukemia/Lymphoma Study Group

Akira Shimada, MD., PhD, Yuka Yamashita, MS, Daisuke Tomizawa, MD, PhD, Akio Tawa, MD, PhD, Tomoyuki Watanabe, PhD, Toshiya Yokozawa, MD, PhD, Kazuko Kudo, MD, PhD, Takashi Taga, MD, PhD, Shotaro Iwamoto, MD, PhD, Kiminori Terui, MD, PhD, Hiroshi Moritake, MD, PhD, Akitoshi Kinoshita, MD, PhD, Hiroyuki Takahashi, MD, PhD, Hideki Nakayama, MD., PhD, Katsuyoshi Koh, MD, Hiroaki Goto, MD., PhD, Yoshiyuki Kosaka, MD, PhD, Akiko Moriya Saito, MD, PhD, Junichiro Fujimoto, MD, PhD, Keizo Horibe, MD, PhD, Kentaro Oki, MD, PhD, Yasuhide Hayashi, MD, PhD, Souichi Adachi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3891.
https://doi.org/10.1182/blood.V122.21.3891.3891
Published: 2013
Journal Articles

Double CEBPA Mutations Are Not Associated With Favorable Clinical Outcome In Pediatric AML: A Report From The Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG)

Hidemasa Matsuo, MT (ASCPi), Mio Kajihara, Daisuke Tomizawa, MD, PhD, Tomoyuki Watanabe, PhD, Akiko Moriya Saito, MD, PhD, Junichiro Fujimoto, MD, PhD, Keizo Horibe, MD, PhD, Mayu Tokumasu, MD, Hiroshi Itoh, Hideki Nakayama, MD, PhD, Akitoshi Kinoshita, MD, PhD, Takashi Taga, MD, PhD, Akio Tawa, MD, PhD, Tomohiko Taki, MD, PhD, Souichi Adachi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4942.
https://doi.org/10.1182/blood.V122.21.4942.4942
Published: 2013
Journal Articles

Appropriate Dose Modification in Induction Therapy Is Essential for the Treatment of Infants with Acute Myeloid Leukemia; A Report From the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG).

Daisuke Tomizawa, Akio Tawa, MD, PhD, Tomoyuki Watanabe, PhD, Akiko Moriya Saito, MD, Kazuko Kudo, Takashi Taga, MD, Shotaro Iwamoto, MD, PhD, Akira Shimada, MD, PhD, Kiminori Terui, MD, PhD, Hiroshi Moritake, MD, PhD, Akitoshi Kinoshita, MD, Hiroyuki Takahashi, MD, PhD, Hideki Nakayama, MD, Katsuyoshi Koh, MD, PhD, Hisato Kigasawa, MD, Yoshiyuki Kosaka, MD, PhD, Hayato Miyachi, MD, PhD, Keizo Horibe, MD, Tatsutoshi Nakahata, MD, PhD, Souichi Adachi, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2615.
https://doi.org/10.1182/blood.V120.21.2615.2615
Published: 2012
Journal Articles

Attempts to Optimize Post-Induction Treatment in Childhood Acute Myeloid Leukemia without Core Binding Factors: A Report From the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG)

Daiichiro Hasegawa, MD, PhD, Akio Tawa, MD, PhD, Daisuke Tomizawa, Tomoyuki Watanabe, PhD, Akiko Saito, MD, PhD, Kazuko Kudo, Takashi Taga, MD, Shotaro Iwamoto, MD, PhD, Akira Shimada, MD, PhD, Kiminori Terui, MD, PhD, Hiroshi Moritake, MD, PhD, Akitoshi Kinoshita, MD, Hiroyuki Takahashi, MD, PhD, Hideki Nakayama, MD, Katsuyoshi Koh, MD, PhD, Hisato Kigasawa, MD, Yoshiyuki Kosaka, MD, PhD, Hayato Miyachi, MD, PhD, Keizo Horibe, MD, Tatsutoshi Nakahata, MD, PhD, Souichi Adachi, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3545.
https://doi.org/10.1182/blood.V120.21.3545.3545
Published: 2012
Journal Articles

Excess Reduction of Anthracyclines Results in Inferior Event-Free Survival in Core Binding Factor Acute Myeloid Leukemia in Children; A Report From the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG)

Daisuke Tomizawa, Akio Tawa, MD, PhD, Tomoyuki Watanabe, PhD, Akiko Moriya Saito, MD, Kazuko Kudo, Takashi Taga, MD, Shotaro Iwamoto, MD, PhD, Akira Shimada, MD, PhD, Kiminori Terui, MD, PhD, Hiroshi Moritake, MD, PhD, Akitoshi Kinoshita, MD, Hiroyuki Takahashi, MD, PhD, Hideki Nakayama, MD, Katsuyoshi Koh, MD, PhD, Hisato Kigasawa, MD, Yoshiyuki Kosaka, MD, PhD, Hayato Miyachi, MD, PhD, Keizo Horibe, MD, Tatsutoshi Nakahata, MD, PhD, Souichi Adachi, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 409.
https://doi.org/10.1182/blood.V120.21.409.409
Published: 2012
Journal Articles

Refractory / Relapsed Myeloid Leukemia of Down Syndrome Is Resistant to Second-Line Chemotherapy and Hardly Salvaged by Hematopoietic Stem Cell Transplantation: A Retrospective Study by the Japanese Pediatric Leukemia / Lymphoma Study Group (JPLSG)

Takashi Taga, MD, PhD, Akiko Saito, MD, PhD, Kazuko Kudo, MD, PhD, Daisuke Tomizawa, MD, Kiminori Terui, MD, PhD, Hiroshi Moritake, MD, PhD, Akitoshi Kinoshita, MD, PhD, Shotaro Iwamoto, MD, PhD, Hideki Nakayama, MD, Hiroyuki Takahashi, MD, PhD, Akio Tawa, MD, PhD, Akira Shimada, MD, PhD, Tomohiko Taki, MD, PhD, Hisato Kigasawa, MD, Katsuyoshi Koh, MD, Souichi Adachi, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4276.
https://doi.org/10.1182/blood.V118.21.4276.4276
Published: 2011
Journal Articles

Unexpected High Mortality Rate Due to Acute Respiratory Distress Syndrome Among Infants with AML Enrolled on JPLSG AML-05 Trial

Daisuke Tomizawa, MD, Akiko Moriya Saito, MD, PhD, Takashi Taga, MD, Souichi Adachi, MD, PhD, Hideki Nakayama, MD, Hiroshi Moritake, MD, PhD, Eiichi Azuma, MD, Akitoshi Kinoshita, MD, Hiroyuki Takahashi, MD, Masue Imaizumi, MD, Kazuko Kudo, MD, Asahito Hama, MD, Masahito Tsurusawa, MD, Keizo Horibe, MD, PhD, Akio Tawa, MD
Journal: Blood
Blood (2010) 116 (21): 2146.
https://doi.org/10.1182/blood.V116.21.2146.2146
Published: 2010
Journal Articles

Combined Analysis of Treatments for Pediatric T-ALL in KYCCSG Protocols, ALL-96 and ALL-02.

Yasuhiro Okamoto, MD, Yoshihisa Nagatoshi, MD, Akinobu Matsuzaki, MD, Aiko Suminoe, MD, Hideki Nakayama, MD, PhD, Noriko Hotta, MD, Shuuichi Ohzono, MD, PhD, Kyoko Fujita, MD, Kiyoshi Kawakami, MD, Fumio Yanai, MD, Hiroshi Moritake, MD, PhD, Jiro Inagaki, MD, Yoshifumi Kawano, MD, PhD, Jun Okamura, MD
Journal: Blood
Blood (2009) 114 (22): 4102.
https://doi.org/10.1182/blood.V114.22.4102.4102
Published: 2009
Journal Articles

Outcome of the ALL-96 Protocol for Childhood ALL from the Kyushu-Yamaguchi Children’s Cancer Study Group.

Yoshihisa Nagatoshi, MD, Aiko Suminoe, MD, Akinobu Matsuzaki, MD, PhD, Koichiro Ueda, MD, Hiroko Inada, MD, Kiyoshi Kawakami, MD, Fumio Yanai, MD, Hideki Nakayama, MD, Hiroshi Moritake, MD, PhD, Nobuyoshi Itonaga, MD, Hiroshi Ayukawa, MD, Kyoko Fujita, MD, Yoshifumi Kawano, MD, Jun Okamura, MD
Journal: Blood
Blood (2005) 106 (11): 877.
https://doi.org/10.1182/blood.V106.11.877.877
Published: 2005