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Journal Articles

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Blood (2019) 134 (Supplement_1): 2525.

https://doi.org/10.1182/blood-2019-126663

Published: 2019

Journal Articles

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Shuhei Asada, MD PhD, Susumu Goyama, MD PhD, Reina Takeda, MD, Keita Yamamoto, MD, Hiroko Kozuka-Hata, PhD, Masaaki Oyama, PhD, Daichi Inoue, MD PhD, Hiroaki Honda, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 731.

https://doi.org/10.1182/blood-2019-125959

Published: 2019

Journal Articles

Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment

Takeshi Fujino, MD, Susumu Goyama, MD PhD, Yuki Sugiura, PhD, Daichi Inoue, MD PhD, Satoshi Yamasaki, PhD, Akiko Matsumoto, Naru Sato, MD, Hironobu Morinaga, PhD, Shiori Shikata, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, PhD, Shuhei Asada, MD PhD, Tsuyoshi Fukushima, MD PhD, Hiroaki Honda, MD PhD, Emi K Nishimura, MD PhD, Tatsuhiro Shibata, MD PhD, Makoto Suematsu, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 821.

https://doi.org/10.1182/blood-2019-127904

Published: 2019

Journal Articles

Utx Insufficiency Cooperates with Braf V600E in the Induction of Myeloma in Mice

Ola Rizq, MD PhD, Naoya Mimura, MD PhD, Motohiko Oshima, PhD, Shuji Momose, MD PhD, Yaeko Nakajima-Takagi, PhD, Kazumasa Aoyama, PhD, Atsunori Saraya, Tohru Iseki, MD PhD, Emiko Sakaida, MD PhD, Chiaki Nakaseko, MDPhD, Yutaka Okuno, MD, PhD, Hiroaki Honda, MD PhD, Jun-ichi Tamaru, MDPhD, Atsushi Iwama, MD PhD

Blood (2018) 132 (Supplement 1): 1005.

https://doi.org/10.1182/blood-2018-99-114053

Published: 2018

Journal Articles

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Yuichiro Nakata, PhD, Norimasa Yamasaki, Takeshi Ueda, MD, PhD, Kenichiro Ikeda, MD, Akiko Nagamachi, PhD, Toshiya Inaba, MD, PhD, Hiroaki Honda, MD, PhD

Blood (2016) 128 (22): 2653.

https://doi.org/10.1182/blood.V128.22.2653.2653

Published: 2016

Journal Articles

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Yuichiro Nakata, Takeshi Ueda, MD PhD, Akiko Nagamachi, PhD, Linda Wolff, PhD, Ogawa Seishi, MD, Toshiya Inaba, MD, Hiroaki Honda, MD PhD

Blood (2014) 124 (21): 4602.

https://doi.org/10.1182/blood.V124.21.4602.4602

Published: 2014

Journal Articles

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Hirotaka Matsui, MD, PhD, Akiko Nagamachi, Akinori Kanai, PhD, Yuko Ozaki, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2013) 122 (21): 227.

https://doi.org/10.1182/blood.V122.21.227.227

Published: 2013

Journal Articles

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Hiroya Asou, MD, PhD, Hiroaki Honda, MD, PhD, Toshiya Inaba, MD, PhD

Blood (2011) 118 (21): 869.

https://doi.org/10.1182/blood.V118.21.869.869

Published: 2011

Journal Articles

Titan (Samd9L), a Candidate -7/7q- Responsible Gene Product, Downregulates Cytokine Signals by Facilitating Formation of Early Endosomes

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Hiroya Asou, MD, Hiroaki Honda, MD, Toshiya Inaba, MD

Blood (2010) 116 (21): 4170.

https://doi.org/10.1182/blood.V116.21.4170.4170

Published: 2010

Journal Articles

Loss of Titan ( Samd9L ), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10 .

Hirotaka Matsui, MD, Akiko Nagamachi, Yuko Ozaki, Daisuke Aki, Hiroya Asou, MD, Hiroaki Honda, MD, Toshiya Inaba, MD

Blood (2009) 114 (22): 2963.

https://doi.org/10.1182/blood.V114.22.2963.2963

Published: 2009

Journal Articles

Haploinsufficiency and Deficiency of a 7q Gene Titan (Samd9L) Predispose Leukemia Development in Cooperation with Deregulated Expression of a Transcription Factor, Evi1, or a Histone Demethylase, Fbxl10

Akiko Nagamachi, Hiroya Asou, MD, Hirotaka Matsui, MD, Yuko Ozaki, Daisuke Aki, PhD, Kazuko Miyazaki, Norimasa Yamasaki, Masaki Miyazaki, MD, Linda Wolff, PhD, Richard Koller, Hideaki Oda, MD, Toshiya Inaba, MD, Hiroaki Honda, MD

Blood (2008) 112 (11): 197.

https://doi.org/10.1182/blood.V112.11.197.197

Published: 2008

NARROW

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment

Utx Insufficiency Cooperates with Braf V600E in the Induction of Myeloma in Mice

JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16 INK4a

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Haploinsufficiency Of SAMD9L , An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7

Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7

Titan (Samd9L), a Candidate -7/7q- Responsible Gene Product, Downregulates Cytokine Signals by Facilitating Formation of Early Endosomes

Loss of Titan ( Samd9L ), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10 .

Haploinsufficiency and Deficiency of a 7q Gene Titan (Samd9L) Predispose Leukemia Development in Cooperation with Deregulated Expression of a Transcription Factor, Evi1, or a Histone Demethylase, Fbxl10

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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