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Hiroshi Yanagawa
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Journal Articles

Elucidation of the IMiDs-Resistant Mechanism and Development of the Overcoming Drugs Inducing CRBN Independent G2/M Cell Cycle Arrest in Myeloma Cells

Ryo Uozaki, Shuji Aida, Takasi Yamagughi, Tomofumi Yamamoto, BPharm, Sho Kashiwazaki, Hiroshi Yanagawa, Daiju Ichikawa, Maiko Matsushita, Yutaka Hattori
Journal: Blood
Blood (2018) 132 (Supplement 1): 4451.
https://doi.org/10.1182/blood-2018-99-115909
Published: 2018
Journal Articles

A Novel Phthalimide-Derivative, TC11, Induced G2/M Arrest and Apoptosis of High-Risk Myeloma Cells By Interacting with Nucleophosmin1 and α-Tubulin, but Not By Binding to Celeblon

Misa Nakamura, Daiju Ichikawa, PhD, Shuji Aida, Nahoko Hashimoto, Wakana Murota, Ryo Uozaki, Mikio Okayama, MD, Kota Fujimori, Yuko Yonemura, Noriko Tabata, PhD, Hiroshi Yanagawa, PhD, Maiko Matsushita, MD PhD, Yutaka Hattori, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5377.
https://doi.org/10.1182/blood.V130.Suppl_1.5377.5377
Published: 2017
Journal Articles

Drug Design for Overcoming High-Risk Myeloma and Identification of Novel Binding Proteins to Immune-Modulatory Drugs

Masashi Hozumi, Daiju Ichikawa, PhD, Maiko Matsushita, MD PhD, Eriko Kamiyama, Hiroshi Yanagawa, PhD, Noriko Tabata, PhD, Shotaro Kitabatake, Arimi Ueda, Takashi Yamaguchi, Mariko Sato, Yutaka Hattori, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1800.
https://doi.org/10.1182/blood.V126.23.1800.1800
Published: 2015
Journal Articles

Development of a Novel Phthalimide Derivative, Preclinical Effects on High-Risk Myeloma Cells and Osteoclasts

Yutaka Hattori, MD PhD, Maiko Matsushita, MD PhD, Noriko Tabata, Hirokazu Shiheido, Hiroshi Yanagawa, PhD, Arimi Ueda, Masashi Hozumi, Shotaro Kitabatake, Daiju Ichikawa
Journal: Blood
Blood (2014) 124 (21): 5718.
https://doi.org/10.1182/blood.V124.21.5718.5718
Published: 2014
Journal Articles

TC11, a Novel Phthalimide Derivative, Directly Binds to NPM1 and Induced Apoptosis of High-Risk Myeloma Cells Via Centrosomal Disruption

Saito Sosei, Kana Yoshikawa, Noriko Tabata, PhD, Hiroshi Yanagawa, PhD, Tsukasa Oikawa, PhD, Wenlin Du, MD, PhD, Taketo Yamada, MD, PhD, Maiko Matsushita, MD, PhD, Junya Seki, Kaoru Tohyama, MD, PhD, Yutaka Hattori, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1841.
https://doi.org/10.1182/blood.V120.21.1841.1841
Published: 2012
Journal Articles

A Novel Anilinoquinazoline Derivative Inhibits Growth of High-Risk Myeloma Cells In Vivo and Regulates Differentiation of Osteoclasts

Yoshie Ozaki, Yuhei Naito, Hiroshi Yanagawa, PhD, Yuya Suzuki, Wenlin Du, MD, PhD, Taketo Yamada, MD, PhD, Koichi Matsuo, MD, PhD, Nobuhide Doi, PhD, Shiro Iijima, PhD, Maiko Matsushita, MD, PhD, Kayoko Tahara, PhD, Yutaka Hattori, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4076.
https://doi.org/10.1182/blood.V116.21.4076.4076
Published: 2010