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Journal Articles

Natural Killer Cells Activated By Oncolytic Reovirus Enhance Cetuximab Mediated Antibody Dependent Cellular Cytotoxicity in an in Vitro and In Vivo Model of Colorectal Cancer

Xing Zhao, PhD, Narendiran Rajasekaran, PhD, Cariad Chester, BA, Atsushi Yonezawa, PhD, Suparna Dutt, PhD, Matt Coffey, Zhixu He, MDPhD, Holbrook E Kohrt, MD PhD

Blood (2015) 126 (23): 3439.

https://doi.org/10.1182/blood.V126.23.3439.3439

Published: 2015

Journal Articles

Phase I/II Clinical Trial of CpG-Activated Whole Cell Vaccine in Mantle Cell Lymphoma (MCL): Results in Safety and Efficacy from Planned Interim Analysis

Blood (2015) 126 (23): 1536.

https://doi.org/10.1182/blood.V126.23.1536.1536

Published: 2015

Journal Articles

Regulatory T Cells Are Depleted in Low-Grade Lymphoma By the Combination of Local Low-Dose Radiation Followed By Intratumoral CpG-ODN

Debra K Czerwinski, Steven R Long, MD, Michael Khodadoust, MD PhD, Matthew J. Frank, MD PhD, Michael P. Chu, MD, Ami Okada, PhD, Kathleen A McDonald, BA, Holbrook E Kohrt, MD PhD, Nancy L Bartlett, MD, Patrick M. Reagan, MD, Jonathan W. Friedberg, MD MMSc, Leo I. Gordon, MD, Robert Coffman, PhD, Robert Janssen, MD, Ronald Levy, MD

Blood (2015) 126 (23): 1539.

https://doi.org/10.1182/blood.V126.23.1539.1539

Published: 2015

Journal Articles

Systemic Antitumor Effects of Intratumoral Administration of the Novel Immunotherapeutic Combination Anti-CTLA4, Anti-CD137, and Anti-OX40 in Mouse Models of Lymphoma and Solid Tumor

Hebb Jonathan, MD MSc, Holbrook E Kohrt, MD PhD

Blood (2015) 126 (23): 1552.

https://doi.org/10.1182/blood.V126.23.1552.1552

Published: 2015

Journal Articles

Three BTK-Specific Inhibitors, in Contrast to Ibrutinib, Do Not Antagonize Rituximab-Dependent NK-Cell Mediated Cytotoxicity

Narendiran Rajasekaran, PhDMSc, Mohith Sadaram, BS, Jonathan Hebb, MD, Idit Sagiv-Barfi, PhD, Sid Ambulkar, Amanda Rajapaksa, Serena Chang, PhD, Cariad Chester, Erin Waller, Lai Wang, PhD, Brian Lannutti, PhD, Dave Johnson, Ron Levy, MD, Holbrook E Kohrt, MD PhD

Blood (2014) 124 (21): 3118.

https://doi.org/10.1182/blood.V124.21.3118.3118

Published: 2014

Journal Articles

Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma

Holbrook E Kohrt, MD PhD, Jaqueline Chu, MD, Joshua Brody, MD, Debra K Czerwinski, Cariad Chester, Mohith Sadaram, BS, Ranjana Advani, MD, Youn H. Kim, MD, Richard T. Hoppe, MD, Susan J. Knox, MD PhD, Irene Wapnir, MD, Robert J. Tibshirani, PhD, Ron Levy, MD

Blood (2014) 124 (21): 3092.

https://doi.org/10.1182/blood.V124.21.3092.3092

Published: 2014

Journal Articles

Obinutuzumab (GA101) Is Less Prone to Antagonism of Immune Effector Function By Ibrutinib Than Rituximab in Vitro and in Vivo

Sylvia Herter, PhD, Idit Sagiv-Barfi, PhD, Cariad Chester, Mohith Sadaram, BS, Jonathan Hebb, MD, Debra K Czerwinski, Narendiran Rajasekaran, PhDMSc, Marina Bacac, PhD, Pablo Umana, PhD, Ron Levy, MD, Christian Klein, PhD, Holbrook E Kohrt, MD PhD

Blood (2014) 124 (21): 1765.

https://doi.org/10.1182/blood.V124.21.1765.1765

Published: 2014

Journal Articles

Conventional CD4 + CD25 - and Regulatory CDCD4 + 25 + t Cells Have Opposite Effects on Progenitor Cells and Hematopoietic Reconstitution Following Stem Cell Transplantation

Antonia MS Mueller, MD, Jessica Poyser, Holbrook E Kohrt, MD PhD, Judith A Shizuru, PhD MD

Blood (2014) 124 (21): 654.

https://doi.org/10.1182/blood.V124.21.654.654

Published: 2014

Journal Articles

High-Throughput Sequencing Of T Cell Receptors Detects Signatures Of T Cell Repertoire That Predict MRD Status In Patients With Mantle Cell Lymphoma Undergoing Immunotransplantation

Malek Faham, MD, PhD, Joshua Brody, MD, Holbrook E Kohrt, MD, PhD, Debra K Czerwinski, Ronald Levy, MD

Blood (2013) 122 (21): 4251.

https://doi.org/10.1182/blood.V122.21.4251.4251

Published: 2013

Journal Articles

Anti-KIR Antibody Enhancement Of Anti-Lymphoma Activity Of Natural Killer Cells As Monotherapy and In Combination With Anti-CD20 Antibodies

Holbrook E Kohrt, MD, PhD, Ariane Thielens, Aurelien Marabelle, MD, MSc, Idit Sagiv Barfi, Caroline Sola, Fabien Chanuc, Nicolas Fuseri, Cécile Bonnafous, Debra K Czerwinski, Amanda Rajapaksa, Erin Waller, Sophie Ugolini, PhD, Eric Vivier, PhD, Francois Romagne, PhD, Ronald Levy, MD, Pascale Andre, PhD, Mathieu Blery, PhD

Blood (2013) 122 (21): 4417.

https://doi.org/10.1182/blood.V122.21.4417.4417

Published: 2013

Journal Articles

Immunotransplant Expands Vaccine-Induced Memory T Cell Responses In Patients With Mantle Cell Lymphoma

Debra K Czerwinski, Joshua Brody, MD, Holbrook E Kohrt, MD, PhD, Malek Faham, MD, PhD, Etelka Gabriel, Robert Negrin, MD, Ronald Levy, MD

Blood (2013) 122 (21): 1816.

https://doi.org/10.1182/blood.V122.21.1816.1816

Published: 2013

Journal Articles

Potentiated B-Cell Antigen Receptor Signaling In Mantle Cell Lymphoma Is Associated With Overexpression Of Surface CD79B and IgM

June Helen Myklebust, PhD, Joshua Brody, MD, Ash A. Alizadeh, MD, PhD, Debra K Czerwinski, Arne Kolstad, MD, PhD, Michael R Green, Ph.D., Roch Houot, MD, PhD, Jan Delabie, MD, PhD, Holbrook E Kohrt, MD, PhD, Jonathan M. Irish, PhD, Ronald Levy, MD

Blood (2013) 122 (21): 1768.

https://doi.org/10.1182/blood.V122.21.1768.1768

Published: 2013

Journal Articles

Ibrutinib (PCI-32765) Antagonizes Rituximab-Dependent NK-Cell Mediated Cytotoxicity

Holbrook E Kohrt, MD, PhD, Idit Sagiv-Barfi, PhD, Sarwish Rafiq, MS, Sarah E.M. Herman, Jonathan P Butchar, Ph.D., Carolyn Cheney, B.S, Xiaoli Zhang, PhD, MS, Joseph J. Buggy, PhD, Natarajan Muthusamy, DVM, Ph.D, Ronald Levy, MD, Amy J Johnson, PhD, John C. Byrd, MD

Blood (2013) 122 (21): 373.

https://doi.org/10.1182/blood.V122.21.373.373

Published: 2013

Journal Articles

Immune Injury by Allogeneic CD4 + T Cells Leads to Host Hematopoietic Stem Cell Dormancy and Prevents Engraftment of Donor Cells.

Antonia MS Mueller, MD, Mareike Florek, MD, Holbrook E Kohrt, MD, PhD, Judith A. Shizuru, MD, PhD

Blood (2012) 120 (21): 2366.

https://doi.org/10.1182/blood.V120.21.2366.2366

Published: 2012

Journal Articles

Non-Myeloablative Conditioning with Total Lymphoid Irradiation and ATG and Allogeneic Transplantation for Patients with Myelodysplastic Syndrome, Therapy-Related Myeloid Neoplasms, and Myeloproliferative Neoplasms.

Jonathan Benjamin, MD, PhD, Saurabh Chhabra, MD, Holbrook E Kohrt, MD, PhD, Ginna G Laport, MD, Sally Arai, MD, Laura Johnston, MD, David B Miklos, MD, PhD, Judith A. Shizuru, MD, PhD, Wen-Kai Weng, MD, PhD, Robert S. Negrin, MD, Robert Lowsky, MD

Blood (2012) 120 (21): 3087.

https://doi.org/10.1182/blood.V120.21.3087.3087

Published: 2012

Journal Articles

CNS Relapse in Acute Promyelocytic Leukemia: Incidence, Management and Outcome

Holbrook E Kohrt, MD, PhD, Steven Coutre, MD

Blood (2012) 120 (21): 1489.

https://doi.org/10.1182/blood.V120.21.1489.1489

Published: 2012

Journal Articles

Acute Leukemia in Hispanic Americans: Incidence and Incidence Rate Differences by Nativity.

Daniel A Pollyea, MD, MS, Holbrook E Kohrt, MD, PhD, Juan Yang, PhD, Ellen T Chang, Sc., D, Scarlett Lin Gomez, PhD, Christina A Clarke, PhD

Blood (2012) 120 (21): 3160.

https://doi.org/10.1182/blood.V120.21.3160.3160

Published: 2012

Journal Articles

Targeting B-Cell Lymphoma with Idiotype-Specific Peptibodies: Toward a Personalized and Tumor-Specific Therapy

James A Torchia, Patrick P Ng, PhD, Homer Chen, Holbrook E Kohrt, MD, PhD, Aurelien Marabelle, MD, MSc, Ash A. Alizadeh, MD, PhD, Ronald Levy, MD

Blood (2012) 120 (21): 3713.

https://doi.org/10.1182/blood.V120.21.3713.3713

Published: 2012

Journal Articles

in Situ Vaccination for Patients with Previously Untreated Follicular Lymphoma: Analysis of Immune Responses

Debra K Czerwinski, Joshua Brody, Holbrook E Kohrt, MD, PhD, Richard T. Hoppe, MD, Ranjana H. Advani, MD, Ronald Levy, MD

Blood (2012) 120 (21): 3703.

https://doi.org/10.1182/blood.V120.21.3703.3703

Published: 2012

Journal Articles

Identification of Candidate Transcriptional Biomarkers Associated with Chronic Graft-Versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation

Holbrook E Kohrt, MD, PhD, Lu Tian, PhD, Li Li, PhD, Ash A. Alizadeh, MD, PhD, Sue Hsieh, PhD, Samuel Strober, MD, Minnie Sarwal, MD PhD, Robert Lowsky, MD

Blood (2012) 120 (21): 4190.

https://doi.org/10.1182/blood.V120.21.4190.4190

Published: 2012

NARROW

Natural Killer Cells Activated By Oncolytic Reovirus Enhance Cetuximab Mediated Antibody Dependent Cellular Cytotoxicity in an in Vitro and In Vivo Model of Colorectal Cancer

Phase I/II Clinical Trial of CpG-Activated Whole Cell Vaccine in Mantle Cell Lymphoma (MCL): Results in Safety and Efficacy from Planned Interim Analysis

Regulatory T Cells Are Depleted in Low-Grade Lymphoma By the Combination of Local Low-Dose Radiation Followed By Intratumoral CpG-ODN

Systemic Antitumor Effects of Intratumoral Administration of the Novel Immunotherapeutic Combination Anti-CTLA4, Anti-CD137, and Anti-OX40 in Mouse Models of Lymphoma and Solid Tumor

Three BTK-Specific Inhibitors, in Contrast to Ibrutinib, Do Not Antagonize Rituximab-Dependent NK-Cell Mediated Cytotoxicity

Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma

Obinutuzumab (GA101) Is Less Prone to Antagonism of Immune Effector Function By Ibrutinib Than Rituximab in Vitro and in Vivo

Conventional CD4 + CD25 - and Regulatory CDCD4 + 25 + t Cells Have Opposite Effects on Progenitor Cells and Hematopoietic Reconstitution Following Stem Cell Transplantation

High-Throughput Sequencing Of T Cell Receptors Detects Signatures Of T Cell Repertoire That Predict MRD Status In Patients With Mantle Cell Lymphoma Undergoing Immunotransplantation

Anti-KIR Antibody Enhancement Of Anti-Lymphoma Activity Of Natural Killer Cells As Monotherapy and In Combination With Anti-CD20 Antibodies

Immunotransplant Expands Vaccine-Induced Memory T Cell Responses In Patients With Mantle Cell Lymphoma

Potentiated B-Cell Antigen Receptor Signaling In Mantle Cell Lymphoma Is Associated With Overexpression Of Surface CD79B and IgM

Ibrutinib (PCI-32765) Antagonizes Rituximab-Dependent NK-Cell Mediated Cytotoxicity

Immune Injury by Allogeneic CD4 + T Cells Leads to Host Hematopoietic Stem Cell Dormancy and Prevents Engraftment of Donor Cells.

Non-Myeloablative Conditioning with Total Lymphoid Irradiation and ATG and Allogeneic Transplantation for Patients with Myelodysplastic Syndrome, Therapy-Related Myeloid Neoplasms, and Myeloproliferative Neoplasms.

CNS Relapse in Acute Promyelocytic Leukemia: Incidence, Management and Outcome

Acute Leukemia in Hispanic Americans: Incidence and Incidence Rate Differences by Nativity.

Targeting B-Cell Lymphoma with Idiotype-Specific Peptibodies: Toward a Personalized and Tumor-Specific Therapy

in Situ Vaccination for Patients with Previously Untreated Follicular Lymphoma: Analysis of Immune Responses

Identification of Candidate Transcriptional Biomarkers Associated with Chronic Graft-Versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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