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Journal Articles

Global Proteomics Identifies CDK11A/B As Integral to Myeloma Proliferation and High-Risk Disease

David E. Mery, Visanu Wanchai, Cody Ashby, Hongwei Xu, Eric Siegel, Clyde Bailey, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1932.
https://doi.org/10.1182/blood-2023-187592
Published: 2023
Journal Articles

The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions

Fumou Sun, Yan Cheng, Jin-Ran Chen, Visanu Wanchai, David E. Mery, Hongwei Xu, Dongzheng Gai, Samer Al Hadidi, Carolina Schinke, Sharmilan Thanendrarajan, Maurizio Zangari, Frits van Rhee, John D Shaughnessy, Jr, Guido Tricot, Fenghuang Zhan
Journal: Blood
Blood (2023) 142 (Supplement 1): 452.
https://doi.org/10.1182/blood-2023-181853
Published: 2023
Journal Articles

Single Nuclei Multiomics Analysis of Transcriptional and Chromatin Accessibility of Tumor Cells Uncovers Molecular Signatures and Regulatory Elements of Malignant Clonal Evolution in Multiple Myeloma

Visanu Wanchai, Hongwei Xu, Cody Ashby, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan
Journal: Blood
Blood (2023) 142 (Supplement 1): 87.
https://doi.org/10.1182/blood-2023-181279
Published: 2023
Journal Articles

Suppression of TRIP13 Induces Metabolic Changes and Potentiates Ferroptosis in Multiple Myeloma

Yan Cheng, Fumou Sun, Wancheng Guo, Hongwei Xu, Prasanth Viswanathan, Mark Manzano, Eric Siegel, Samer Al Hadidi, Carolina Schinke, Maurizio Zangari, Marta Chesi, P. Leif Bergsagel, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3309.
https://doi.org/10.1182/blood-2023-187001
Published: 2023
Journal Articles

A 12 Gene Signature Accurately Predicts Multiple Myeloma Progression from Monoclonal Gammopathy of Undetermined Significance

Fumou Sun, Jun Ying, Yan Cheng, David Mery, Visanu Wanchai, Eric R. Siegel, Hongwei Xu, Dongzheng Gai, Jiahao Xu, Timothy Cody Ashby, Clyde Bailey, Samer Al Hadidi, Carolina Schinke, Sharmilan Thanendrarajan, Maurizio Zangari, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan
Journal: Blood
Blood (2022) 140 (Supplement 1): 264–265.
https://doi.org/10.1182/blood-2022-163654
Published: 2022
Journal Articles

Bispecific CAR-T Cells Targeting Both BCMA and CD24: A Potentially Treatment Approach for Multiple Myeloma

Fumou Sun, Yan Cheng, Bailu Peng, Hongwei Xu, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr., Fenghuang Zhan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2802.
https://doi.org/10.1182/blood-2021-148543
Published: 2021
Journal Articles

NEK2 Inhibition Enhances the Efficacy of PD-1/PD-L1 Blockade in Multiple Myeloma

Yan Cheng, Fumou Sun, Huojun Cao, Dongzheng Gai, Bailu Peng, Hongwei Xu, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr., Fenghuang Zhan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2671.
https://doi.org/10.1182/blood-2021-148659
Published: 2021
Journal Articles

The Interaction of NEK2 with USP7 Causes Resistance to Proteasome Inhibitor in Multiple Myeloma

Reinaldo Franqui-Machin, Mu Hao, PhD, Bai Hua, Zhimin Gu, PhD, Xin Zhan, Hongwei Xu, Hasem Habelhah, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Lugui Qiu, MD, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 593.
https://doi.org/10.1182/blood.V130.Suppl_1.593.593
Published: 2017
Journal Articles

Multiple Myeloma Tumor Cells Are Selectively Killed By Pharmacologically-Dosed Ascorbic Acid

Reinaldo Franqui-Machin, Hongwei Xu, Yogesh Yethava, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5391.
https://doi.org/10.1182/blood.V130.Suppl_1.5391.5391
Published: 2017
Journal Articles

Nek2 Stabilization By Usp7 Leads to Activation of NF-Kb in Multiple Myeloma

Reinaldo Franqui Machin, BS, Xin Zhan, BA, Hongwei Xu, DDS, Ivana Frech, DSc, PhD MBA, Guido J Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4418.
https://doi.org/10.1182/blood.V128.22.4418.4418
Published: 2016
Journal Articles

Drug Resistant Myeloma Cells Cause More Severe Bone Destruction in Myeloma

Mu Hao, MD PhD, Zhimin Gu, PhD, Reinaldo Franqui Machin, Hongwei Xu, Gregory S. Thomas, PhD, Lugui Qiu, MD PhD, Guido J Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2015) 126 (23): 839.
https://doi.org/10.1182/blood.V126.23.839.839
Published: 2015
Journal Articles

Targeting Neddylation to Overcome Drug Resistance in Multiple Myeloma

Gregory S Thomas, PhD, Junwei Huang, MD, Yi Zhou, PhD, Zhimin Gu, PhD, Ye Yang, PhD, Hongwei Xu, Guido J Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1804.
https://doi.org/10.1182/blood.V126.23.1804.1804
Published: 2015
Journal Articles

Decreased FPN1 in Myeloma Promotes Malignant Cell Growth and Osteoclast Differentiation

Zhimin Gu, PhD, He Wang, PhD, Jiliang Xia, MS, Ivana De Domenico, PhD, Ye Yang, PhD, Junwei Huang, MD, Hongwei Xu, DDS, Zhengdong Jin, PhD, Guido J. Tricot, MD, PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2017.
https://doi.org/10.1182/blood.V124.21.2017.2017
Published: 2014
Journal Articles

NEK2 Suppresses Cellular Senescence through Regulation of the β-Catenin/CCND2/RB Axis in Multiple Myeloma

Ye Yang, PhD, Guido J. Tricot, MD, PhD, Xia Jiliang, Zhimin Gu, PhD, Hongwei Xu, DDS, Mu Hao, PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2024.
https://doi.org/10.1182/blood.V124.21.2024.2024
Published: 2014
Journal Articles

Elevated Expression Of CKS1B Inhibits Senescence Thorough Enhanced Degradation Of p21 In Multiple Myeloma

Zhimin Gu, PhD, Yi Zhou, PhD, He Wang, MD, Ye Yang, PhD, Hongwei Xu, DDS, Junwei Huang, MD, Jie He, MD, Yi Tao, MD&PhD, Guido J. Tricot, M.D., Ph.D., Fenghuang Zhan, MD&PhD
Journal: Blood
Blood (2013) 122 (21): 1882.
https://doi.org/10.1182/blood.V122.21.1882.1882
Published: 2013
Journal Articles

High Trip13 and Low P31 Comet Cause Drug Resistance and Poor Prognosis In Multiple Myeloma

Yi Tao, MD&PhD, Zhimin Gu, PhD, Ye Yang, PhD, Hongwei Xu, DDS, Xiaojing Hu, Guido J. Tricot, M.D., Ph.D., Fenghuang Zhan, MD&PhD, Jumei Shi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3820.
https://doi.org/10.1182/blood.V122.21.3820.3820
Published: 2013
Journal Articles

RARα2 Expression Confers Myeloma Stem Cell Features

Guido J. Tricot, M.D., Ph.D., Ye Yang, PhD, Zhimin Gu, PhD, Hongwei Xu, DDS, Junwei Huang, MD, Jie He, MD, Yi Tao, MD&PhD, Fenghuang Zhan, MD&PhD
Journal: Blood
Blood (2013) 122 (21): 5404.
https://doi.org/10.1182/blood.V122.21.5404.5404
Published: 2013
Journal Articles

Targeting BTK As a Treatment For Multiple Myeloma Stem Cells

Ye Yang, PhD, Zhimin Gu, PhD, Hongwei Xu, DDS, Junwei Huang, MD, Jie He, MD, Yi Tao, MD&PhD, Guido J. Tricot, M.D., Ph.D., Fenghuang Zhan, MD&PhD
Journal: Blood
Blood (2013) 122 (21): 271.
https://doi.org/10.1182/blood.V122.21.271.271
Published: 2013
Journal Articles

RARα2 expression confers myeloma stem cell features

Ye Yang, Jumei Shi, Giulia Tolomelli, Hongwei Xu, Jiliang Xia, He Wang, Wen Zhou, Yi Zhou, Satyabrata Das, Zhimin Gu, Dana Levasseur, Fenghuang Zhan, Guido Tricot
Journal: Blood
Blood (2013) 122 (8): 1437–1447.
https://doi.org/10.1182/blood-2013-02-482919
Published: 2013
Includes: Supplemental data
Journal Articles

NEK2 Regulates Immature B Cell Development and GC Formation in NEK2 Transgenic Mouse

Wen Zhou, PhD, Xiao He, He Wang, Mohamed E Salama, M.D., Xia Jiliang, Hongwei Xu, MD, MS, Maurizio Zangari, MD, Guido J. Tricot, MD, PhD, Fenghuang Zhan, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 257.
https://doi.org/10.1182/blood.V120.21.257.257
Published: 2012