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Hua Wang, Ph.D
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Journal Articles

The Novel Human Double Minute (HDM)-2 Inhibitor DS-5272 Is Active Both Alone, and In Combination With Other Novel Agents, Against Multiple Myeloma

Dongmin Gu, M.D., Ph.D., Hua Wang, Ph.D., Zhiqiang Wang, Ph.D., Richard E. Davis, M.D., Shengli Cai, M.D., Ph.D., Takahiko Seki, Ph.D., Archie Tse, M.D., Ph.D., Robert Z. Orlowski, M.D., Ph.D
Journal: Blood
Blood (2013) 122 (21): 1927.
https://doi.org/10.1182/blood.V122.21.1927.1927
Published: 2013
Journal Articles

Expression Of Truncated Protein Tyrosine Phosphatase, Receptor Type, O (PTPROt) Influences Multiple Myeloma Sensitivity To Bortezomib Through Akt Signaling, and Is a Favorable Clinical Prognostic Factor

Hua Wang, Ph.D., Veerabhadran Baladandayuthapani, Ph.D., Zhiqiang Wang, Ph.D., Jiexin Zhang, Heather Yan Lin, Ph.D., Richard E. Davis, M.D., Lin Yang, Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 2520.
https://doi.org/10.1182/blood.V122.21.2520.2520
Published: 2013
Journal Articles

CX-5461, a Novel RNA Polymerase I Inhibitor, Is Active Against Wild-Type and Mutant p53 Myeloma Models

Hans C. Lee, MD, Hua Wang, Ph.D., Bing-Zong Li, M.D., Ph.D., Zhiqiang Wang, Ph.D., Richard Julian Jones, Ph.D., Dongmin Gu, M.D., Ph.D., Sean O'Brien, Ph.D., Richard E. Davis, M.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 4438.
https://doi.org/10.1182/blood.V122.21.4438.4438
Published: 2013
Journal Articles

Proteasome Maturation Protein (pomp) Is Associated With Proteasome Inhibitor Resistance In Myeloma, and Its Suppression Enhances The Activity Of Bortezomib and Carfilzomib

Bingzong Li, M.D., Ph.D., Hua Wang, Ph.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 280.
https://doi.org/10.1182/blood.V122.21.280.280
Published: 2013
Journal Articles

Inhibition of the HDM-2 E3 Ligase Induces Types I and II Cell Death in Wild-Type and Mutant p53 Models of Multiple Myeloma, and Acts Synergistically in Both with ABT-737.

Dongmin Gu, Ph.D., Richard Julian Jones, Ph.D., Hua Wang, Ph.D., Lance Leopold, M.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 2940.
https://doi.org/10.1182/blood.V120.21.2940.2940
Published: 2012
Journal Articles

Blockade of IGF-1R with OSI-906 Overcomes Bortezomib-Resistance in Multiple Myeloma

Deborah J. Kuhn, Ph.D., Hua Wang, Ph.D., Richard Julian Jones, PhD, Chad C. Bjorklund, Ph.D., Robert Z. Orlowski, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 925.
https://doi.org/10.1182/blood.V118.21.925.925
Published: 2011
Journal Articles

Validation of Potential Chemosensitivity Genes in Multiple Myeloma

Lin Yang, Ph.D, Xingding Zhang, Ph.D, Hua Wang, Ph.D, Robert Z. Orlowski, MD, PhD, Xingxu Huang, Ph.D
Journal: Blood
Blood (2011) 118 (21): 1818.
https://doi.org/10.1182/blood.V118.21.1818.1818
Published: 2011