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Hui Yang, PhDMD
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Journal Articles

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice

Yue Wei, PhD, Hong Zheng, Naran Bao, Rashmi Kanagal-Shamanna, MD, Caleb Class, PhD, Hui Yang, PhDMD, Guillermo Montalban Bravo, MD, Irene Ganan-Gomez, PhD, Kelly Soltysiak, PhD, Kim-Ann Do, Simona Colla, PhD, Carlos E. Bueso-Ramos, MD PhD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 562.
https://doi.org/10.1182/blood-2019-122574
Published: 2019
Journal Articles

Long-Term Follow up of a Randomized Phase 2 Study of Low-Dose Decitabine Versus Low-Dose Azacitidine in Lower-Risk Myelodysplastic Syndromes

Guillermo Montalban-Bravo, MD, Elias Jabbour, MD, Caleb Class, PhD, Nicholas J. Short, MD, Rashmi Kanagal-Shamanna, MD, Tapan M. Kadia, MD, Gautam M. Borthakur, MD, Naveen Pemmaraju, MD, Koji Sasaki, MD, Zeev E. Estrov, MD, Jorge E. Cortes, MD, Farhad Ravandi, MD, Yesid Alvarado, MD, Rami S. Komrokji, MD, Mikkael A. Sekeres, MD MS, David P. Steensma, MD, Amy E. DeZern, MD, Gail J. Roboz, MD, Hui Yang, PhDMD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1715.
https://doi.org/10.1182/blood-2019-129141
Published: 2019
Journal Articles

Comprehensive DNA 5-Hydroxymethylation Landscapes in Myelodysplastic Syndromes (MDS)

Jia Li, PhD, Yue Wei, PhD, Minjung Lee, MS, Caleb Class, PhD, Hui Yang, PhDMD, Deqiang Sun, PhD, Guillermo Garcia-Manero, MD, Yun Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2996.
https://doi.org/10.1182/blood-2019-128599
Published: 2019
Journal Articles

Transcriptomic Analysis Implicates Necroptosis in Disease Progression and Prognosis in Myelodysplastic Syndromes

Guillermo Montalban-Bravo, MD, Caleb Class, PhD, Irene Ganan-Gomez, PhD, Rashmi Kanagal-Shamanna, MD, Koji Sasaki, MD, Guillaume Richard-Carpentier, MD, Kiran Naqvi, MDMPH, Yue Wei, PhD, Hui Yang, PhDMD, Kelly Soltysiak, PhD, Kelly S. Chien, MD, Carlos E. Bueso-Ramos, MD PhD, Kim-Anh Do, PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3006.
https://doi.org/10.1182/blood-2019-124957
Published: 2019
Journal Articles

Single-Cell RNA Sequencing Reveals Distinct Hematopoietic Stem Cell Hierarchies in MDS

Irene Ganan-Gomez, PhD, Hui Yang, PhDMD, Feiyang Ma, Bs, Matteo Pellegrini, PhD, Karen Clise-Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 771.
https://doi.org/10.1182/blood-2019-128798
Published: 2019
Journal Articles

High-Resolution Next-Generation Whole Genome Optical Mapping As a Novel Molecular Diagnostic Tool for Comprehensive Assessment of Structural Chromosomal Variations in Myelodysplastic Syndromes

Rashmi Kanagal-Shamanna, MD, Guillermo Montalban-Bravo, MD, Koji Sasaki, MD, Rajyalakshmi Luthra, PhD, Hui Yang, PhDMD, Gokce A. Toruner, MD PhD, Keyur P. Patel, MBBS, PhD, Saradhi Mallampati, DVM, PhD, Hagop M. Kantarjian, MD, Carlos E. Bueso-Ramos, MD PhD, L. Jeffrey Medeiros, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5438.
https://doi.org/10.1182/blood-2019-131971
Published: 2019
Journal Articles

Cell-Type Specific Mechanisms of Hematopoietic Stem Cell (HSC) Expansion Underpin Progressive Disease in Myelodysplastic Syndromes (MDS) and Provide a Rationale for Targeted Therapies

Irene Ganan-Gomez, PhD, Ana Alfonso, MD PhD, Hui Yang, PhDMD, Andrea Santoni, PhD, Valentina Marchica, MS, Elena Fiorini, MS, Guillermo Montalban-Bravo, MD, Yamini Ogoti, Ganiraju Manyam, Shan Jiang, Naran Bao, Christopher Jackson, Ashley Rose, Rashmi Kanagal-Shamanna, MD, Carlos E. Bueso-Ramos, MD PhD, Benedetta Cambò, MD, Nicola Giuliani, MD PhD, Monica Crugnola, MD, Marina Y. Konopleva, MD PhD, Karen Clise-Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1798.
https://doi.org/10.1182/blood-2018-99-116881
Published: 2018
Journal Articles

Induced PD-1 Expression on Bone Marrow CD34+ Cells from MDS Patients Treated with 5-Azacitadine in Combination with Nivolumab and/or Ipilimumab

Hui Yang, PhDMD, Zhihong Fang, Karen Clise-Dwyer, PhD, Kathryn Ruisaard, Simona Colla, PhD, Irene Ganan-Gomez, PhD, Guillermo Montalban-Bravo, MD, Kelly Soltysiak, Naval G. Daver, MD, Elias J. Jabbour, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1807.
https://doi.org/10.1182/blood-2018-99-119278
Published: 2018