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Journal Articles

Inhibition of MDM2 Improves the Therapeutic Effect of Hypomethylating Agents in Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)

Yue Wei, Hong Zheng, Pamela Lockyer, Naran Bao, Faezeh Darbaniyan, Ziyi Li, Rashmi Kanagal-Shamanna, Kelly A. Soltysiak, Hui Yang, Irene Ganan-Gomez, Kim-Anh Do, Simona Colla, Kelly S. Chien, Guillermo Montalban-Bravo, Naval Daver, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 3664.
https://doi.org/10.1182/blood-2021-150811
Published: 2021
Journal Articles

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice

Yue Wei, PhD, Hong Zheng, Naran Bao, Rashmi Kanagal-Shamanna, MD, Caleb Class, PhD, Hui Yang, PhDMD, Guillermo Montalban Bravo, MD, Irene Ganan-Gomez, PhD, Kelly Soltysiak, PhD, Kim-Ann Do, Simona Colla, PhD, Carlos E. Bueso-Ramos, MD PhD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 562.
https://doi.org/10.1182/blood-2019-122574
Published: 2019
Journal Articles

Cell-Type Specific Mechanisms of Hematopoietic Stem Cell (HSC) Expansion Underpin Progressive Disease in Myelodysplastic Syndromes (MDS) and Provide a Rationale for Targeted Therapies

Irene Ganan-Gomez, PhD, Ana Alfonso, MD PhD, Hui Yang, PhDMD, Andrea Santoni, PhD, Valentina Marchica, MS, Elena Fiorini, MS, Guillermo Montalban-Bravo, MD, Yamini Ogoti, Ganiraju Manyam, Shan Jiang, Naran Bao, Christopher Jackson, Ashley Rose, Rashmi Kanagal-Shamanna, MD, Carlos E. Bueso-Ramos, MD PhD, Benedetta Cambò, MD, Nicola Giuliani, MD PhD, Monica Crugnola, MD, Marina Y. Konopleva, MD PhD, Karen Clise-Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1798.
https://doi.org/10.1182/blood-2018-99-116881
Published: 2018
Journal Articles

Overexpression of Histone Demethylase KDM6B in the Hematopoietic Compartment Promotes the Effect of Innate Immune Activation and Results in Myelodysplastic Syndrome (MDS)-like Phenotype in Mice

Yue Wei, PhD, Guillermo Garcia-Manero, MD, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Joseph David Khoury, MD, Caleb Class, Simona Colla, PhD, Carlos E. Bueso-Ramos, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 50.
https://doi.org/10.1182/blood.V130.Suppl_1.50.50
Published: 2017
Journal Articles

Overexpression of KDM6B, an Epigenetic and Innate Immune Regulator, Results in Hematopoietic Alterations of Mice Including Changes in Hematopoietic Stem Cells

Yue Wei, PhD, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Simona Colla, PhD, Carlos E Bueso-Ramos, MD PhD, Joseph D Khoury, MD, Zachary S. Bohannan, MA, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2016) 128 (22): 3149.
https://doi.org/10.1182/blood.V128.22.3149.3149
Published: 2016
Journal Articles

Effect of Azacytidine on the Hematopoietic Stem and Progenitor Cell Compartments of MDS Mouse Models: Unveiling the Mechanisms of Remission and Relapse

Irene Gañán-Gómez, PhD, Yamini Ogoti, Matteo Marchesini, PhD, Yue Wei, PhD, Hui Yang, MD PhD, Shan Jiang, Naran Bao, Carlos E. Bueso-Ramos, MD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2015) 126 (23): 2852.
https://doi.org/10.1182/blood.V126.23.2852.2852
Published: 2015