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Ian J. Mackie
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Journal Articles

C5 Polymorphism in a Dutch Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) and No Asian Ancestry, Resistant to Eculizumab, but in Vitro Sensitive to Coversin

Saskia Langemeijer, MD PhD, Jun-Ichi Nishimura, MD PhD, Wynne Weston-Davies, Miles A Nunn, DPhil, Yuzuru Kanakura, MD PhD, Ian J Mackie, Petra Muus, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1209.
https://doi.org/10.1182/blood.V126.23.1209.1209
Published: 2015
Journal Articles

Rivaroxaban Limits Complement Activation Compared to Warfarin in Antiphospholipid Syndrome Patients with Venous Thromboembolism

Deepa Jayakody Arachchillage, Ian J Mackie, Maria Efthymiou, Andrew Chitolie, Beverley J Hunt, David Isenberg, Munther Khamashta, Samuel Machin, Hannah Cohen
Journal: Blood
Blood (2015) 126 (23): 2328.
https://doi.org/10.1182/blood.V126.23.2328.2328
Published: 2015
Journal Articles

Clinical and Immunological Characterisation of Coversin, a Novel Small Protein Inhibitor of Complement C5 with Potential As a Therapeutic Agent in PNH and Other Complement Mediated Disorders

Wynne H Weston-Davies, MB FRCS, Miles A Nunn, DPhil, Fernando O Pinto, MDFRCPath, Ian J Mackie, PhDFRCPath, Stephen John Richards, PhD FRCPath, Samuel J Machin, MDFRCPath, Raymond Prudo, MB FRCP(C) MRCPsych, Peter Hillmen, MBChB, PhD
Journal: Blood
Blood (2014) 124 (21): 4280.
https://doi.org/10.1182/blood.V124.21.4280.4280
Published: 2014
Journal Articles

Plasma FXIII LEVEL Variations During Menstrual CYCLE

Susan Halimeh, MD, Lava A. Talat Sharief, Andrew S. Lawrie, Guenther Kappert, Ian J. Mackie, PhD FRCPath, Flora Peyvandi, Rezan A. Kadir
Journal: Blood
Blood (2013) 122 (21): 4777.
https://doi.org/10.1182/blood.V122.21.4777.4777
Published: 2013
Journal Articles

Residual plasmatic activity of ADAMTS13 is correlated with phenotype severity in congenital thrombotic thrombocytopenic purpura

Luca A. Lotta, Haifeng M. Wu, Ian J. Mackie, Marina Noris, Agnes Veyradier, Marie A. Scully, Giuseppe Remuzzi, Paul Coppo, Ri Liesner, Roberta Donadelli, Chantal Loirat, Richard A. Gibbs, April Horne, Shangbin Yang, Isabella Garagiola, Khaled M. Musallam, Flora Peyvandi
Journal: Blood
Blood (2012) 120 (2): 440–448.
https://doi.org/10.1182/blood-2012-01-403113
Published: 2012
Includes: Supplemental data
Journal Articles

Residual Plasmatic Activity of ADAMTS13 in Congenital Thrombotic Thrombocytopenic Purpura Correlates with Disease Phenotype

Luca A Lotta, Haifeng M Wu, Marie A Scully, Marina Noris, Agnes Veyradier, Ian J Mackie, PhD FRCPath, Giuseppe Remuzzi, Paul Coppo, Ri Liesner, Roberta Donadelli, Chantal Loirat, MD, Richard A Gibbs, April Horne, Shangbin Yang, Roberta Palla, Flora Peyvandi
Journal: Blood
Blood (2011) 118 (21): 2219.
https://doi.org/10.1182/blood.V118.21.2219.2219
Published: 2011
Journal Articles

The Prognostic Effects of Anti-ADAMTS13 IgG, IgA and IgM Antibody Subclasses In Acute Idiopathic TTP and the Effect of Rituximab,

Vickie McDonald, MA, MRCP, FRCPath, Samuel J Machin, MD FRCPath, Ian J Mackie, PhD FRCPath, Marie A Scully, MD FRCPath
Journal: Blood
Blood (2011) 118 (21): 3305.
https://doi.org/10.1182/blood.V118.21.3305.3305
Published: 2011
Journal Articles

Idiopathic Non-Cirrhotic Intrahepatic Portal Hypertension Is Associated with Sustained ADAMTS13 Deficiency.

Ian J Mackie, PhD, FRCPath, Chundamannil E Eapen, MD, Neil Desley, MD, Elwyn Elias, MD, BSc, FRCP
Journal: Blood
Blood (2008) 112 (11): 2296.
https://doi.org/10.1182/blood.V112.11.2296.2296
Published: 2008
Journal Articles

The Effect of Plasma Exchange on Rituximab Levels and Response to Rituximab in Patients with Acute Idiopathic Thrombotic Thrombocytopenic Pupura (TTP).

Vickie McDonald, MA, MRCP, FRCPath, Marie Scully, MRCP, FRCPath, MD, Ian J. Mackie, PhD, FRCPath, Kate Manns, BA, Samuel J. Machin, FRCP, FRCPath, MD
Journal: Blood
Blood (2008) 112 (11): 2297.
https://doi.org/10.1182/blood.V112.11.2297.2297
Published: 2008
Journal Articles

Molecular weight-Dependent Mechanism of Heparin Neutralization by Platelet factor 4.

Martine Marie Fiore, PhD, Ian J Mackie
Journal: Blood
Blood (2008) 112 (11): 2017.
https://doi.org/10.1182/blood.V112.11.2017.2017
Published: 2008
Journal Articles

Dual Effect of Platelet Factor Four on the Activities of Factor Xa

Martine Marie Fiore, PhD, Ian J Mackie
Journal: Blood
Blood (2008) 112 (11): 1034.
https://doi.org/10.1182/blood.V112.11.1034.1034
Published: 2008
Journal Articles

Pronounced Reduction in ADAMTS13 Activity Occurs in Heparin Induced Thrombocytopenia but Is Not Due to IgG ANTI-ADAMTS13.

Steven K. Austin, MBBS, Simon J. Davidson, Andrew S. Lawrie, Ian J. Mackie, Samuel J. Machin
Journal: Blood
Blood (2007) 110 (11): 2085.
https://doi.org/10.1182/blood.V110.11.2085.2085
Published: 2007
Journal Articles

High Affinity Autoantibodies to ADAMTS13 in the Antiphospholipid Syndrome.

Steven K. Austin, MD, Richard D. Starke, PhD, Gordon Purdy, Andrew S. Lawrie, FIBMS, Samuel J. Machin, MD, Ian J. Mackie, PhD
Journal: Blood
Blood (2006) 108 (11): 1467.
https://doi.org/10.1182/blood.V108.11.1467.1467
Published: 2006
Journal Articles

A Genetic Basis for Adult Onset TTP?.

Raymond S. Camilleri, Ian J. Mackie, Marie Scully, Samuel J. Machin, Hannah Cohen
Journal: Blood
Blood (2005) 106 (11): 1228.
https://doi.org/10.1182/blood.V106.11.1228.1228
Published: 2005