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Journal Articles

Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-141411

Published: 2020

Journal Articles

SF3B1 -Mutant Myelodysplastic Syndrome with Ringed Sideroblasts (MDS-RS) at the Single-Cell Level

Rashmi Kanagal-Shamanna, MD, Vera Adema, PhD, Feiyang Ma, Bs, Andrea Santoni, PhD, Hui Yang, MD PhD, Irene Ganan-Gomez, PhD, Natthakan Thongon, PhD, Guillermo Montalban-Bravo, MD, Matteo Pellegrini, PhD, Carlos E. Bueso-Ramos, MD PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2020) 136 (Supplement 1): 50–51.

https://doi.org/10.1182/blood-2020-141928

Published: 2020

Journal Articles

Transcriptomic Features and Deregulation of Genes Involved in Monopoiesis Influence Outcomes of Patients with Chronic Myelomonocytic Leukemia

Guillermo Montalban Bravo, MD, Faezeh Darbaniyan, PhD, Rashmi Kanagal-Shamanna, MD, Irene Ganan-Gomez, PhD, Koji Sasaki, MD, Kiran Naqvi, MD MPH, Yue Wei, PhD, Hui Yang, MD PhD, Kelly A. Soltysiak, PhD, Kelly S. Chien, MD, Carlos E. Bueso-Ramos, MD PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 50–51.

https://doi.org/10.1182/blood-2020-137702

Published: 2020

Journal Articles

Genomic and Transcriptomic Differences of Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T) and Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)

Guillermo Montalban Bravo, MD, Rashmi Kanagal-Shamanna, MD, Faezeh Darbaniyan, PhD, Irene Ganan-Gomez, PhD, Koji Sasaki, MD, Kiran Naqvi, MD MPH, Yue Wei, PhD, Hui Yang, MD PhD, Kelly A. Soltysiak, PhD, Kelly S. Chien, MD, Carlos E. Bueso-Ramos, MD PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2020) 136 (Supplement 1): 18–19.

https://doi.org/10.1182/blood-2020-139983

Published: 2020

Journal Articles

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice

Yue Wei, PhD, Hong Zheng, Naran Bao, Rashmi Kanagal-Shamanna, MD, Caleb Class, PhD, Hui Yang, PhDMD, Guillermo Montalban Bravo, MD, Irene Ganan-Gomez, PhD, Kelly Soltysiak, PhD, Kim-Ann Do, Simona Colla, PhD, Carlos E. Bueso-Ramos, MD PhD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 562.

https://doi.org/10.1182/blood-2019-122574

Published: 2019

Journal Articles

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

Rashmi Kanagal-Shamanna, MD, Guillermo Montalban-Bravo, MD, Caleb Class, PhD, Koji Sasaki, MD, Christopher B. Benton, MD, Kelly Soltysiak, PhD, Elias Jabbour, MD, Tapan M. Kadia, MD, Carlos E. Bueso-Ramos, MD PhD, Keyur P. Patel, MBBS, PhD, Mark Routbort, MD PhD, Irene Ganan-Gomez, PhD, Yue Wei, PhD, Gautam M. Borthakur, MD, Farhad Ravandi, MD, Kim-Anh Do, PhD, L. Jeffrey Medeiros, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 1719.

https://doi.org/10.1182/blood-2019-130545

Published: 2019

Journal Articles

Transcriptomic Analysis Implicates Necroptosis in Disease Progression and Prognosis in Myelodysplastic Syndromes

Guillermo Montalban-Bravo, MD, Caleb Class, PhD, Irene Ganan-Gomez, PhD, Rashmi Kanagal-Shamanna, MD, Koji Sasaki, MD, Guillaume Richard-Carpentier, MD, Kiran Naqvi, MDMPH, Yue Wei, PhD, Hui Yang, PhDMD, Kelly Soltysiak, PhD, Kelly S. Chien, MD, Carlos E. Bueso-Ramos, MD PhD, Kim-Anh Do, PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 3006.

https://doi.org/10.1182/blood-2019-124957

Published: 2019

Journal Articles

Single-Cell RNA Sequencing Reveals Distinct Hematopoietic Stem Cell Hierarchies in MDS

Irene Ganan-Gomez, PhD, Hui Yang, PhDMD, Feiyang Ma, Bs, Matteo Pellegrini, PhD, Karen Clise-Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2019) 134 (Supplement_1): 771.

https://doi.org/10.1182/blood-2019-128798

Published: 2019

Journal Articles

Landscape of TP53 Abnormalities and Their Clinical Relevance in Patients with Myelodysplastic Syndromes and Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 2791.

https://doi.org/10.1182/blood-2018-99-119706

Published: 2018

Journal Articles

Mutational and Clonal Landscape of Acute Myeloid Leukemia with Myelodysplastic Related Changes

Blood (2018) 132 (Supplement 1): 1514.

https://doi.org/10.1182/blood-2018-99-119899

Published: 2018

Journal Articles

Telomere Damage Maintains Hematopoietic Stem Cells (HSCs) in an Activated Metabolic State, Which Compromises Their Self-Renewal Capability

Andrea Santoni, PhD, Elena Fiorini, MS, Fides D Lay, PhD BSc, Matteo Marchesini, PhD, Yamini Ogoti, Christopher Jackson, Ashley Rose, Karen Clise-Dwyer, PhD, Irene Ganan-Gomez, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2018) 132 (Supplement 1): 174.

https://doi.org/10.1182/blood-2018-174

Published: 2018

Journal Articles

Cell-Type Specific Mechanisms of Hematopoietic Stem Cell (HSC) Expansion Underpin Progressive Disease in Myelodysplastic Syndromes (MDS) and Provide a Rationale for Targeted Therapies

Blood (2018) 132 (Supplement 1): 1798.

https://doi.org/10.1182/blood-2018-99-116881

Published: 2018

Journal Articles

Induced PD-1 Expression on Bone Marrow CD34+ Cells from MDS Patients Treated with 5-Azacitadine in Combination with Nivolumab and/or Ipilimumab

Hui Yang, PhDMD, Zhihong Fang, Karen Clise-Dwyer, PhD, Kathryn Ruisaard, Simona Colla, PhD, Irene Ganan-Gomez, PhD, Guillermo Montalban-Bravo, MD, Kelly Soltysiak, Naval G. Daver, MD, Elias J. Jabbour, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2018) 132 (Supplement 1): 1807.

https://doi.org/10.1182/blood-2018-99-119278

Published: 2018

Journal Articles

ILF2-YB1 Protein Interaction Modulates RNA Splicing to Induce Resistance to Chemotherapy in High Risk Multiple Myeloma

Matteo Marchesini, PhD, Yamini Ogoti, MS, Elena Fiorini, MS, Marianna D'anca, PhD, Paola Storti, PhD, Luigi Nezi, PhD, Mehmet K. Samur, PhD, Irene Gañán-Gómez, PhD, Mariateresa Fulciniti, PhD, Zachary S. Bohannan, MA, Karen Clise-Dwyer, PhD, Nicola Giuliani, MD PhD, Nikhil C Munshi, MD, Robert Z. Orlowski, PhD, MD, Guillermo Garcia-Manero, MD, Ronald A. DePinho, Simona Colla, PhD

Blood (2016) 128 (22): 359.

https://doi.org/10.1182/blood.V128.22.359.359

Published: 2016

Journal Articles

Hematopoietic Architecture of MDS before and after Progression Reveals Two Biologically Distinct Disease Subtypes

Irene Gañán-Gómez, PhD, Ana Alfonso, MD, Yamini Ogoti, MS, Hui Yang, MD PhD, Guillermo Montalban-Bravo, MD, Abraham C Yu, BS, Matteo Marchesini, PhD, Carlos E Bueso-Ramos, MD PhD, Koichi Takahashi, MD, Karen Clise-Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2016) 128 (22): 4310.

https://doi.org/10.1182/blood.V128.22.4310.4310

Published: 2016

Journal Articles

Anti-Leukemia Effect of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Acute Myeloid Leukemia

Hui Yang, MD PhD, Zachary S. Bohannan, MA, Zhihong Fang, Irene Gañán-Gómez, PhD, Yue Wei, PhD, Linda J. Paradiso, DVM, MBA, Hiroyuki Iwamura, Dphil, Guillermo Garcia-Manero, MD

Blood (2016) 128 (22): 2756.

https://doi.org/10.1182/blood.V128.22.2756.2756

Published: 2016

Journal Articles

The Role of Chip-Related DNA Damage Response Dysfunction in Therapy-Related Myeloid Neoplasms

Ana Alfonso Pierola, MDPhD, Matteo Marchesini, PhD, Koichi Takahashi, MD, Irene Gañán-Gómez, PhD, Elena Fiorini, MS, Yamini Ogoti, MS, Esperanza Irles, PhD, Guillermo Montalban-Bravo, MD, Silver Sofia, BS, Karen C. Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2016) 128 (22): 958.

https://doi.org/10.1182/blood.V128.22.958.958

Published: 2016

Journal Articles

Effect of Azacytidine on the Hematopoietic Stem and Progenitor Cell Compartments of MDS Mouse Models: Unveiling the Mechanisms of Remission and Relapse

Irene Gañán-Gómez, PhD, Yamini Ogoti, Matteo Marchesini, PhD, Yue Wei, PhD, Hui Yang, MD PhD, Shan Jiang, Naran Bao, Carlos E. Bueso-Ramos, MD, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2015) 126 (23): 2852.

https://doi.org/10.1182/blood.V126.23.2852.2852

Published: 2015

Journal Articles

Telomere Dysfunction-Induced DNA Damage Drives Hematopoietic Stem Cell Fate

Matteo Marchesini, PhD, Yamini Ogoti, Irene Ganan-Gomez, PhD MSc, Yue Wei, PhD, Carlos E. Bueso-Ramos, Guillermo Garcia-Manero, MD, Ronald A. DePinho, Simona Colla, PhD

Blood (2015) 126 (23): 1156.

https://doi.org/10.1182/blood.V126.23.1156.1156

Published: 2015

Journal Articles

PDE4 Differential Expression Is a Potential Prognostic Factor and a Therapeutic Target in Myelodysplastic Syndromes

Ali N. Chamseddine, MD, Yue Wei, PhD, Monica Cabrero, MD, Irene Ganan-Gomez, PhD MSc, Simona Colla, PhD, Koichi Takahashi, MD, Hui Yang, MD PhD, Marcos R Estecio, PhD, Zachary S. Bohannan, MA, Sherry Pierce, BSN, BA, Carlos E. Bueso-Ramos, MD, Hagop M Kantarjian, MD, Elias Jabbour, Guillermo Garcia-Manero, MD

Blood (2015) 126 (23): 5227.

https://doi.org/10.1182/blood.V126.23.5227.5227

Published: 2015

NARROW

Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis

SF3B1 -Mutant Myelodysplastic Syndrome with Ringed Sideroblasts (MDS-RS) at the Single-Cell Level

Transcriptomic Features and Deregulation of Genes Involved in Monopoiesis Influence Outcomes of Patients with Chronic Myelomonocytic Leukemia

Genomic and Transcriptomic Differences of Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T) and Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS)

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia

Transcriptomic Analysis Implicates Necroptosis in Disease Progression and Prognosis in Myelodysplastic Syndromes

Single-Cell RNA Sequencing Reveals Distinct Hematopoietic Stem Cell Hierarchies in MDS

Landscape of TP53 Abnormalities and Their Clinical Relevance in Patients with Myelodysplastic Syndromes and Acute Myeloid Leukemia

Mutational and Clonal Landscape of Acute Myeloid Leukemia with Myelodysplastic Related Changes

Telomere Damage Maintains Hematopoietic Stem Cells (HSCs) in an Activated Metabolic State, Which Compromises Their Self-Renewal Capability

Cell-Type Specific Mechanisms of Hematopoietic Stem Cell (HSC) Expansion Underpin Progressive Disease in Myelodysplastic Syndromes (MDS) and Provide a Rationale for Targeted Therapies

Induced PD-1 Expression on Bone Marrow CD34+ Cells from MDS Patients Treated with 5-Azacitadine in Combination with Nivolumab and/or Ipilimumab

ILF2-YB1 Protein Interaction Modulates RNA Splicing to Induce Resistance to Chemotherapy in High Risk Multiple Myeloma

Hematopoietic Architecture of MDS before and after Progression Reveals Two Biologically Distinct Disease Subtypes

Anti-Leukemia Effect of FF-10501-01, a Novel Inosine 5'-Monophosphate Dehydrogenase Inhibitor, in Acute Myeloid Leukemia

The Role of Chip-Related DNA Damage Response Dysfunction in Therapy-Related Myeloid Neoplasms

Effect of Azacytidine on the Hematopoietic Stem and Progenitor Cell Compartments of MDS Mouse Models: Unveiling the Mechanisms of Remission and Relapse

Telomere Dysfunction-Induced DNA Damage Drives Hematopoietic Stem Cell Fate

PDE4 Differential Expression Is a Potential Prognostic Factor and a Therapeutic Target in Myelodysplastic Syndromes

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American Society of Hematology

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American Society of Hematology

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