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Israel Vlodavsky
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Journal Articles

Defibrotide for the Treatment of Endotheliitis Complicating Sars-Cov-2 Infection: Rationale and Ongoing Studies As Part of the International Defacovid Study Group

Jose M. Moraleda, MD, Carmelo Carlo-Stella, MD, David Garcia-Bernal, PhD, Ruben Jara Rubio, MD, Enriqueta Andreu, MD, Eleonora Calabretta, MD, Alessio Aghemo, MD, Maribel Diaz-Ricart, Marta Palomo, PhD, Enric Carreras, MD PhD, Israel Vlodavsky, PhD, Massimo Iacobelli, Jawed Fareed, PhD, Pedro Castro, MD PhD, Sara Fernandez, MD, Clifton C. Mo, MD, Gerald L. Weinhouse, MD, Kenneth R. Cooke, MD, Robert J. Soiffer, MD, Rebecca M. Baron, MD, Peter O'Gorman, MD PhD FRCP, FRCPath, Gregory Yanik, MD, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Paul G. Richardson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–8.
https://doi.org/10.1182/blood-2020-141872
Published: 2020
Journal Articles

Functional rs4693608 SNP is Located into Strong Hpse Gene Intron Enhancer and Thereby Influences to the Ability of Nuclear Proteins Binding and Activity of This Enhancer in Broad Number of Hematological Cell Lines and ALL/AML Primary Samples

Olga Ostrovsky, PhD, Ania Hava Grushchenko Polaq, Katia Beider, PhD, Rita Mayorov, Avichai Shimoni, MD, Israel Vlodavsky, PhD, Arnon Nagler
Journal: Blood
Blood (2016) 128 (22): 3934.
https://doi.org/10.1182/blood.V128.22.3934.3934
Published: 2016
Journal Articles

Heparanase Activation of the Coagulation System in a Mice Sepsis Model

Israel Henig, MD, Elena Axelman, MSc., Benjamin Brenner, MD, Israel Vlodavsky, Ph.D, Yona Nadir, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 378.
https://doi.org/10.1182/blood.V118.21.378.378
Published: 2011
Journal Articles

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

Sara Massena, Gustaf Christoffersson, Elina Hjertström, Eyal Zcharia, Israel Vlodavsky, Nora Ausmees, Charlotte Rolny, Jin-Ping Li, Mia Phillipson
Journal: Blood
Blood (2010) 116 (11): 1924–1931.
https://doi.org/10.1182/blood-2010-01-266072
Published: 2010
Includes: Multimedia, Supplemental data
Journal Articles

Genetic variations in the heparanase gene ( HPSE ) associate with increased risk of GVHD following allogeneic stem cell transplantation: effect of discrepancy between recipients and donors

Olga Ostrovsky, Avichai Shimoni, Avital Rand, Israel Vlodavsky, Arnon Nagler
Journal: Blood
Blood (2010) 115 (11): 2319–2328.
https://doi.org/10.1182/blood-2009-08-236455
Published: 2010
Includes: Supplemental data
Journal Articles

Genetic Variations in Heparanase Gene (HPSE) Are Associated with Increased Risk of Graft Vs. Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation: Effect of Discrepancy Between Recipient and Donor.

Olga Ostrovsky, Avichai Shimoni, Israel Vlodavsky, Arnon Nagler
Journal: Blood
Blood (2009) 114 (22): 3556.
https://doi.org/10.1182/blood.V114.22.3556.3556
Published: 2009
Journal Articles

Anti-Heparanase Therapy in Combination with Conventional Chemotherapy Potently Inhibits Multiple Myeloma Growth in Vivo

Joseph P. Ritchie, Annamaria Naggi, Giangiacomo Torri, Benito Casu, Claudio Pisano, Paolo Carminati, Israel Vlodavsky, Ralph D. Sanderson, Yang Yang
Journal: Blood
Blood (2008) 112 (11): 5165.
https://doi.org/10.1182/blood.V112.11.5165.5165
Published: 2008
Journal Articles

The Heparanase Inhibitor SST0001 Is a Potent Inhibitor of Myeloma Growth In Vivo

Yang Yang, Joseph P. Ritchie, Telisha Swain, Annamaria Naggi, Giangiacomo Torri, Benito Casu, Claudio Pisano, Paolo Carminati, Israel Vlodavsky, Ralph D. Sanderson
Journal: Blood
Blood (2008) 112 (11): 246.
https://doi.org/10.1182/blood.V112.11.246.246
Published: 2008
Journal Articles

Involvement of Heparanase in Early Pregnancy Losses

Yona Nadir, M.D., Ph.D, Israel Henig, M.D., Israel Vlodavsky, Ph.D., Benjamin Brenner, M.D.
Journal: Blood
Blood (2008) 112 (11): 4081.
https://doi.org/10.1182/blood.V112.11.4081.4081
Published: 2008
Journal Articles

Heparanase regulates retention and proliferation of primitive Sca-1 + /c-Kit + /Lin − cells via modulation of the bone marrow microenvironment

Asaf Spiegel, Eyal Zcharia, Yaron Vagima, Tomer Itkin, Alexander Kalinkovich, Ayelet Dar, Orit Kollet, Neta Netzer, Karin Golan, Itay Shafat, Neta Ilan, Arnon Nagler, Israel Vlodavsky, Tsvee Lapidot
Journal: Blood
Blood (2008) 111 (10): 4934–4943.
https://doi.org/10.1182/blood-2007-10-116145
Published: 2008
Journal Articles

A Heparin-Based Inhibitor of Heparanase Blocks Myeloma Growth In Vivo by Targeting the Tumor Microenvironment.

Yang Yang, MD, PhD, Telisha Swain, BA, Annamaria Naggi, PhD, Giangiacomo Torri, PhD, Benito Casu, PhD, Israel Vlodavsky, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2007) 110 (11): 1502.
https://doi.org/10.1182/blood.V110.11.1502.1502
Published: 2007
Journal Articles

The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy

Yang Yang, Veronica MacLeod, Yuemeng Dai, Yekaterina Khotskaya-Sample, Zachary Shriver, Ganesh Venkataraman, Ram Sasisekharan, Annamaria Naggi, Giangiacomo Torri, Benito Casu, Israel Vlodavsky, Larry J. Suva, Joshua Epstein, Shmuel Yaccoby, John D. Shaughnessy, Jr, Bart Barlogie, Ralph D. Sanderson
Journal: Blood
Blood (2007) 110 (6): 2041–2048.
https://doi.org/10.1182/blood-2007-04-082495
Published: 2007
Journal Articles

Role of endothelial heparanase in delayed-type hypersensitivity

Evgeny Edovitsky, Immanuel Lerner, Eyal Zcharia, Tamar Peretz, Israel Vlodavsky, Michael Elkin
Journal: Blood
Blood (2006) 107 (9): 3609–3616.
https://doi.org/10.1182/blood-2005-08-3301
Published: 2006
Journal Articles

Co-Interaction and Increased Release of Tissue Factor Pathway Inhibitor by Heparanase.

Yona Nadir, MD, Benjamin Brenner, MD, Anna Zetser, PhD, Flonia Levy-Adam, M.Sc., Victoria Kaplan, M.Sc., Eyal Zcharia, PhD, Orit Goldshmidt, PhD, Israel Vlodavsky, PhD
Journal: Blood
Blood (2005) 106 (11): 4038.
https://doi.org/10.1182/blood.V106.11.4038.4038
Published: 2005