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Ivana Frech, DSc, PhD MBA
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Journal Articles

Iron Trafficking through Macrophages Regulates Signaling Pathways in Myeloma

Xuelian Tan, Timothy Cody Ashby, PhD, Yuqi Zhu, Can Li, MD, Xuxing Shen, MBBS, Qierra Brockman, BA, Dongzheng Gai, MD, Sarah K Johnson, PhD, Donghoon Yong, Carolina D. Schinke, MD, Maurizio Zangari, MD FACP, Frits van Rhee, MD, John Shaughnessy, Jr., PhD, Dingming Huang, PhD, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2.
https://doi.org/10.1182/blood-2020-140372
Published: 2020
Journal Articles

Altered Iron Metabolism Is a New Targetable Hallmark for Multiple Myeloma

Can Li, MD, Xuelian Tan, Qierra Brockman, BA, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Marta Chesi, PhD, P. Leif Bergsagel, MD, Fangping Chen, MD PhD, Ivana Frech, DSc, PhD MBA, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3059.
https://doi.org/10.1182/blood-2019-123473
Published: 2019
Journal Articles

Targeting NEK2 Induces Cellular Senescence in B-Cell Malignancies through p53-Independent Signaling Pathways

Yuqi Zhu, Ye Yang, PhD, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3102.
https://doi.org/10.1182/blood-2019-123815
Published: 2019
Journal Articles

Development of an Easily Accessible Patient-Derived Xenograft (PDX) Mouse Model in Multiple Myeloma

Can Li, MD, Yogesh Jethava, MBBS, MDFRCPath, MRCP, Ivana Frech, DSc, PhD MBA, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5538.
https://doi.org/10.1182/blood-2019-121933
Published: 2019
Journal Articles

TRIP13 Modulates Protein Deubiquitination to Promote Myeloma Progression

Can Li, MD, Reinaldo Franqui-Machin, Jiliang Xia, PhD, Gregory S. Thomas, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Fangping Chen, MD PhD, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 854.
https://doi.org/10.1182/blood-2019-123818
Published: 2019
Journal Articles

The Nek2 Genetic Knockout Mouse Model Provides Novel Treatment Strategies in Myeloma and Lymphoma

Li Can, MD, Kalyan Nadiminti, Yuqi Zhu, Yogesh Jethava, MBBS, MD FRCPath, MRCP, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5612.
https://doi.org/10.1182/blood-2018-99-115099
Published: 2018
Journal Articles

The Interaction of NEK2 with USP7 Causes Resistance to Proteasome Inhibitor in Multiple Myeloma

Reinaldo Franqui-Machin, Mu Hao, PhD, Bai Hua, Zhimin Gu, PhD, Xin Zhan, Hongwei Xu, Hasem Habelhah, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Lugui Qiu, MD, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 593.
https://doi.org/10.1182/blood.V130.Suppl_1.593.593
Published: 2017
Journal Articles

Multiple Myeloma Tumor Cells Are Selectively Killed By Pharmacologically-Dosed Ascorbic Acid

Reinaldo Franqui-Machin, Hongwei Xu, Yogesh Yethava, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5391.
https://doi.org/10.1182/blood.V130.Suppl_1.5391.5391
Published: 2017
Journal Articles

Clinical Investigation of Mitochondrial Biogenesis in Multiple Myeloma

Xin Zhan, Reinaldo Franqui-Machin, Kalyan Nadiminti, MD, Huojun Cao, Brad A. Amendt, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Ivana Frech, DSc, PhD MBA, Fenghuang Zhan, MD PhD, Guido J. Tricot, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1785.
https://doi.org/10.1182/blood.V130.Suppl_1.1785.1785
Published: 2017
Journal Articles

Nek2 Stabilization By Usp7 Leads to Activation of NF-Kb in Multiple Myeloma

Reinaldo Franqui Machin, BS, Xin Zhan, BA, Hongwei Xu, DDS, Ivana Frech, DSc, PhD MBA, Guido J Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4418.
https://doi.org/10.1182/blood.V128.22.4418.4418
Published: 2016