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Journal Articles

Tolerability and Clinical Activity of Novel First in Class Oral Agent, Inobrodib (CCS1477), in Combination with Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma

Emma Searle, James Cavet, Victoria Campbell, Steve Knapper, Ceri Bygrave, Dima El-Sharkawi, Charlotte Pawlyn, Maria Creignou, Harriet Walter, David Valcárcel, Marta Hidalgo Soto, Jenny O'Nions, Amrutha Sridhar, Tomasz Knurowski, Karen Clegg, Neil Pegg, Will Henry West, Debbie Haynes, Kris Frese, Tim Somervaille
Journal: Blood
Blood (2023) 142 (Supplement 1): 2005.
https://doi.org/10.1182/blood-2023-174652
Published: 2023
Journal Articles

Potent Pre-Clinical and Early Phase Clinical Activity of EP300/CBP Bromodomain Inhibitor CCS1477 in Multiple Myeloma

Luciano Nicosia, Nigel Brooks, Fabio Amaral, Oliver Sinclair, Neil A Pegg, William West, Tomasz Knurowski, Kris Frese, Karen Clegg, James Cavet, Emma Searle, Tim C.P Somervaille
Journal: Blood
Blood (2022) 140 (Supplement 1): 852–853.
https://doi.org/10.1182/blood-2022-157535
Published: 2022
Journal Articles

Use of Cryopreserved Allogeneic PBSC Results in Delayed Engraftment and Increased Incidence of Poor Graft Function

Samar Kulkarni, John Murray, James Clarke, Mike Dennis, Amit Patel, Anna Castleton, James Cavet, Angela Leather, Lyndsey Ashton, Diane Sweeney, Joanna Tomlins, Adrian Bloor, Rita Angelica, Mark Williams
Journal: Blood
Blood (2021) 138 (Supplement 1): 1778.
https://doi.org/10.1182/blood-2021-154199
Published: 2021
Journal Articles

Post Allograft Rituximab Responsive Cytopenia (RRC)

Samar Kulkarni, MD, John Murray, RGN, MSc, David Kaye, MSc, Michael Dennis, FRCPath, Anna Castleton, FRCPath, Mohd K Mamat, MRCP, James Cavet, Daniel Wiseman, FRCPath, Tim Somervaille, FRCPath, Sven Sommerfeld, MRCP, Richard Chasty, FRCPath, Adrian Bloor, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 5645.
https://doi.org/10.1182/blood-2019-132214
Published: 2019
Journal Articles

Determinants of Long-Term Survival Following Allogeneic Stem Cell Transplantation for Multiple Myeloma: A Multi-Centre Analysis Across the United Kingdom and Australia

Salvatore Fiorenza, MBBS PhDMPH BSc, David J M Routledge, MSc, PGCert, MRCP, FRCPath, Jenny Collins, BSc, Michael J Shipton, MBChB, BSc, Simon J. Harrison, MBBS,MRCP,FRCPath,FRACP,PhD, James Cavet, Eleni Tholouli, MD PhD, David Ritchie, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4569.
https://doi.org/10.1182/blood.V130.Suppl_1.4569.4569
Published: 2017
Journal Articles

Outcomes with Extracorporeal Photopheresis in the Management of Chronic Gvhd: A Multi-Centre Experience

David Routledge, MSc, BSc (Hons), FRCPath, MRCP, John Murray, BSc (hons), MSc, Fiona Dignan, MD, Amanda Calderwood, Adrian Bloor, Eleni Tholouli, Therese Callaghan, Muhammad Ameer Saif, MD FRCPath, MBBS, MRCP, Michael Dennis, FRCPath, James Cavet, FRCPath, Samar Kulkarni, MD MRCP, FRCPath
Journal: Blood
Blood (2016) 128 (22): 4595.
https://doi.org/10.1182/blood.V128.22.4595.4595
Published: 2016
Journal Articles

Seattle Regimen RIC-HSCT in Early-Phase Multiple Myeloma: A Multi-Centre Experience Demonstrating Very Low Treatment-Related Mortality and Rapid Graft-Versus-Myeloma Effect Associated with Graft-Versus-Host Disease

Michael J Shipton, MBChB, BSc, David JM Routledge, MRCP, Neil Bodagh, MBChB, BSc, James Cavet, FRCPath, Eleni Tholouli, Samar Kulkarni, FRCPath, Simon DJ Gibbs
Journal: Blood
Blood (2015) 126 (23): 4355.
https://doi.org/10.1182/blood.V126.23.4355.4355
Published: 2015
Journal Articles

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Of The Efficacy and Safety Of Siltuximab, An Anti-Interleukin-6 Monoclonal Antibody, In Patients With Multicentric Castleman’s Disease

Raymond S Wong, Corey Casper, Nikhil Munshi, Xiaoyan Ke, Alexander Fosså, David Simpson, Marcelo Capra, Ting Liu, MD, Ruey Kuen Hsieh, Yeow Tee Goh, Jun Zhu, Seok-Goo Cho, Hanyun Ren, James Cavet, Rajesh Bandekar, Margaret Rothman, Thomas A Puchalski, Shalini Chaturvedi, Helgi van de Velde, Jessica Vermeulen, Frits van Rhee
Journal: Blood
Blood (2013) 122 (21): 505.
https://doi.org/10.1182/blood.V122.21.505.505
Published: 2013
Journal Articles

HCT-CI Does Not Reliably Predict Outcome Following Allogeneic Stem Cell Transplant Due to Poor Correlation Between Clinical and Laboratory Assessment of Comorbidities

John Murray, RGN, MSc, Mike Dennis, MD, MRCP, FRCPath, James Cavet, PhD, FRCP, FRCPath, Samar Kulkarni, MD, MRCP, FRCPath, Adrian JC Bloor, PhD, FRCP, FRCPath
Journal: Blood
Blood (2011) 118 (21): 4562.
https://doi.org/10.1182/blood.V118.21.4562.4562
Published: 2011
Journal Articles

Utility of Second and Subsequent Peripheral Blood Stem Cell (PBSC) Mobilization in Myeloma Patients

Samar Kulkarni, MD, MRCP, FRCPath, Adrian JC Bloor, PhD, FRCP, FRCPath, Mike Dennis, Dianne Sweeney, Rita Angelica, Sarah Grantham, Siobhan Donaghey, Angela Leather, Lyndsey Ashton, James Cavet
Journal: Blood
Blood (2011) 118 (21): 4401.
https://doi.org/10.1182/blood.V118.21.4401.4401
Published: 2011
Journal Articles

The Role of High Dose Chemotherapy and Autologous Stem Cell Transplantation In Patients with Multiple Myeloma Refractory to Initial Induction Therapy

Christopher Parrish, MA, MB, BChir, MRCP, Amin Rahemtulla, MBBS, PhD, FRCP, James Cavet, BA, MBBS, FRCP(UK), FRCPath, PhD., Rachel Pearce, Kirkland Keiran, MSc, SRN, Julia Lee, Charles Craddock, Keith Wilson, Gordon Cook, MD, PhD, FRCP, (Glas), FRCPath, FRCPI
Journal: Blood
Blood (2010) 116 (21): 1341.
https://doi.org/10.1182/blood.V116.21.1341.1341
Published: 2010
Journal Articles

Thyroid Function Abnormalities In Adults Following Haematopoetic Stem Cell Transplant (HSCT).

John Murray, RGN, MSc, James Cavet, BA, MBBS, FRCP(UK), FRCPath, PhD., Adrian Bloor, PhD, MRCP, FRCPath, Samar Kulkarni, MD, MRCP, Michael Dennis, FRCP, FRCPath, Malcolm Blower, MSc, Ric Swindell, Georg Brabant, MD, PhD, FRCP
Journal: Blood
Blood (2010) 116 (21): 1305.
https://doi.org/10.1182/blood.V116.21.1305.1305
Published: 2010
Journal Articles

A Phase 3 Prospective Randomized International Study (MMY-3021) Comparing Subcutaneous and Intravenous Administration of Bortezomib In Patients with Relapsed Multiple Myeloma

Philippe Moreau, Halyna V Pylypenko, Sebastian Grosicki, Evgeniy E Karamanesht, Xavier Leleu, Maria E Grishunina, Grigoriy B Rekhtman, Zvenyslava Masliak, Tadeusz Robak, Anna V Shubina, Jean-Paul Fermand, Martin Kropff, James Cavet, Sudha Parasuraman, Huaibao Feng, Donna M Skee, Helgi van de Velde, William M Deraedt, Jean-Luc Harousseau
Journal: Blood
Blood (2010) 116 (21): 312.
https://doi.org/10.1182/blood.V116.21.312.312
Published: 2010
Journal Articles

Distal Limb Infiltration by Transformed Lymphoplasmacytoid Lymphoma.

James Cavet, MRCPath, PhD, Daniel Wiseman, MBChB
Journal: Blood
Blood (2006) 108 (11): 4647.
https://doi.org/10.1182/blood.V108.11.4647.4647
Published: 2006
Journal Articles

Trauma Site Localisation of Extramedullary Plasmacytomata in Thalidomide Treated Myeloma Patients.

James Cavet, MRCPath, PhD, Hamish Hunter, MRCP, Gordon Cook, FRCPath, PhD
Journal: Blood
Blood (2006) 108 (11): 5069.
https://doi.org/10.1182/blood.V108.11.5069.5069
Published: 2006
Journal Articles

The Fate of Human Langerhans Cells in Hematopoietic Stem Cell Transplantation.

Matthew P. Collin, MD, Derek N. Hart, MD, Graham H. Jackson, MD, Gordon Cook, MD, James Cavet, MD, Stephen Mackinnon, MD, Anne M. Dickinson, PhD
Journal: Blood
Blood (2005) 106 (11): 572.
https://doi.org/10.1182/blood.V106.11.572.572
Published: 2005
Journal Articles

Interferon-γ and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation

James Cavet, Anne M. Dickinson, Jean Norden, Penelope R. A. Taylor, Graham H. Jackson, Peter G. Middleton
Journal: Blood
Blood (2001) 98 (5): 1594–1600.
https://doi.org/10.1182/blood.V98.5.1594
Published: 2001
Journal Articles

Recipient Tumor Necrosis Factor- and Interleukin-10 Gene Polymorphisms Associate With Early Mortality and Acute Graft-Versus-Host Disease Severity in HLA-Matched Sibling Bone Marrow Transplants

James Cavet, Peter G. Middleton, Miriam Segall, Harriet Noreen, Stella M. Davies, Anne M. Dickinson
Journal: Blood
Blood (1999) 94 (11): 3941–3946.
https://doi.org/10.1182/blood.V94.11.3941
Published: 1999