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Journal Articles

Phase 1 Study of Tabalumab, a Human Anti-BAFF Antibody and Bortezomib in Patients with Previously-Treated Multiple Myeloma

Noopur Raje, MD, Edward Anthony Faber, Jr., DO, MS, Paul G. Richardson, MD, Gary J. Schiller, MD, Raymond J. Hohl, MD, PhD, Adam D. Cohen, MD, Andres Forero, MD, Susan P. Carpenter, PhD, Damien Cronier, PhD, Christopher Kaiser, PhD, James E. Wooldridge, MD, Kenneth C. Anderson, MD

Blood (2012) 120 (21): 447.

https://doi.org/10.1182/blood.V120.21.447.447

Published: 2012

Journal Articles

Sustained Depletion of B-Cells by a Humanized, Fc-Engineered Anti-CD20 Antibody, AME-133v, in Patients with Relapsed Follicular Lymphoma

Jennifer Wayne, MS, Kristen N. Ganjoo, MD, Andres Forero, MD, Brad Pohlman, MD, Sven de Vos, MD, PhD, Susan P. Carpenter, PhD, James E Wooldridge, MD, Shashidhara Marulappa, DVM, MVSc, MBA, Vinay Jain, MBBS, MD, FACP

Blood (2011) 118 (21): 4977.

https://doi.org/10.1182/blood.V118.21.4977.4977

Published: 2011

Journal Articles

Phase I Study of a New Humanized Anti-CD20 Monoclonal Antibody (LY2469298) in Japanese Patients (pts) with Relapsed or Refractory Follicular Lymphoma (FL) Pretreated with Rituximab-Containing Regimen

Michinori Ogura, MD, PhD, Kensei Tobinai, MD, PhD, Toshiki Uchida, MD, PhD, Yukio Kobayashi, MD, PhD, Takashi Oyama, MD, Takashi Watanabe, MD, PhD, Tatsuya Suzuki, MD, PhD, Dai Maruyama, MD, PhD, Masanobu Kasai, MD, Masakazu Mori, MD, Tomomi Matsue, Damien Cronier, PhD, James E Wooldridge, MD, Minori Koshiji, MD, PhD

Blood (2010) 116 (21): 3942.

https://doi.org/10.1182/blood.V116.21.3942.3942

Published: 2010

Journal Articles

Genetic Polymorphisms In Genes Involved In R-CHOP Metabolism and Event-Free and Overall Survival In Diffuse Large B-Cell Lymphoma

James R Cerhan, MD, PhD, Thomas M Habermann, MD, Matthew J Maurer, MS, James E Wooldridge, MD, Stephen M Ansell, MD, PhD, Grzegorz S. Nowakowski, MD, Ivana N Micallef, MD, Carrie A Thompson, MD, Alice H Wang, BA, William R Macon, MD, Sergei I Syrbu, MD, Susan L Slager, PhD, Thomas E Witzig, MD, Brian Link

Blood (2010) 116 (21): 996.

https://doi.org/10.1182/blood.V116.21.996.996

Published: 2010

Journal Articles

A Phase I Safety Study of Enzastaurin Plus Bortezomib in the Treatment of Relapsed or Refractory Multiple Myeloma.

Irene M Ghobrial, Nikhil C Munshi, Brianna N Harris, Zheng Yuan, Nichole M Porter, Robert L Schlossman, Jacob P Laubach, Kenneth C. Anderson, Courtney E Lin, James E Wooldridge, Paul G Richardson, Rafat Abonour

Blood (2009) 114 (22): 1870.

https://doi.org/10.1182/blood.V114.22.1870.1870

Published: 2009

Journal Articles

Enzastaurin in Previously Treated Waldenstrom's Macroglobulinemia: An Open-Label, Multicenter, Phase II Study.

Irene M Ghobrial, Jean-Luc Harousseau, Steven P Treon, Brianna Harris, Courtney E Lin, Zheng Yuan, Karim Benhadji, James E Wooldridge, Veronique Leblond

Blood (2009) 114 (22): 3867.

https://doi.org/10.1182/blood.V114.22.3867.3867

Published: 2009

Journal Articles

Oral Tipifarnib (R115777) Has Single Agent Anti-Tumor Activity in Patients with Relapsed Aggressive Non-Hodgkin Lymphoma (NHL): Results of a Phase II Trial in the University of Iowa/Mayo Clinic Lymphoma SPORE (CA97274).

Thomas E. Witzig, MD, Matthew J. Maurer, Patrick B. Johnston, MD, Joseph P. Colgan, MD, Scott H. Kaufmann, MD, PhD, David J. Inwards, MD, Ivana N. Micallef, MD, Stephen M. Ansell, MD, PhD, Clive S. Zent, MD, Cristine Allmer, George J. Weiner, MD, James E. Wooldridge, MD, Brian K. Link, MD, Thomas M. Habermann, MD

Blood (2006) 108 (11): 530.

https://doi.org/10.1182/blood.V108.11.530.530

Published: 2006

Journal Articles

IL-21 Plus CpG ODN Induces Granzyme B-Dependent Induction of Apoptosis in CD5-Positive B Cells Including B-CLL Cells.

Sue E. Blackwell, Bernd Jahrsdoerfer, MD, James E. Wooldridge, MD, Jian Huang, Melinda W. Andreski, Laura S. Jacobus, Christiana M. Taylor, George J. Weiner, MD

Blood (2006) 108 (11): 2823.

https://doi.org/10.1182/blood.V108.11.2823.2823

Published: 2006

Journal Articles

B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation

Bernd Jahrsdörfer, Sue E. Blackwell, James E. Wooldridge, Jian Huang, Melinda W. Andreski, Laura S. Jacobus, Christiana M. Taylor, George J. Weiner

Blood (2006) 108 (8): 2712–2719.

https://doi.org/10.1182/blood-2006-03-014001

Published: 2006

Includes: Supplemental data

Journal Articles

Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab

Julie A. Bowles, Siao-Yi Wang, Brian K. Link, Barrett Allan, Gregory Beuerlein, Mary-Ann Campbell, David Marquis, Brian Ondek, James E. Wooldridge, Brian J. Smith, James B. Breitmeyer, George J. Weiner

Blood (2006) 108 (8): 2648–2654.

https://doi.org/10.1182/blood-2006-04-020057

Published: 2006

Journal Articles

Anti-CD20 Monoclonal Antibody (mAb) with Enhanced Affinity for CD16 Activates NK Cells at Lower Concentrations and More Effectively Than Rituximab ®.

George J. Weiner, MD, Julie A. Bowles, BS, Brian K. Link, MD, Mary A. Campbell, PhD, James E. Wooldridge, MD, James B. Breitmeyer, MD, PhD

Blood (2005) 106 (11): 348.

https://doi.org/10.1182/blood.V106.11.348.348

Published: 2005

Journal Articles

IL-21 and CpG ODN Are Synergistic in Their Ability To Induce Apoptosis of Chronic Lymphocytic Leukemia (CLL) Cells and Benign B1 Cells.

Bernd Jahrsdoerfer, MD, Sue E. Blackwell, James E. Wooldridge, MD, Melinda W. Andreski, Laura S. Jacobus, Christiana M. Taylor, George J. Weiner, MD

Blood (2005) 106 (11): 5022.

https://doi.org/10.1182/blood.V106.11.5022.5022

Published: 2005

Journal Articles

A Polymorphism in the C1qA Component of Complement Correlates with Prolonged Complete Remission Following Rituximab Therapy of Follicular Lymphoma.

Emilian Racila, MD, Wen-Kai Weng, MD, James E. Wooldridge, MD, Brian K. Link, MD, Ronald Levy, MD, George J. Weiner, MD

Blood (2005) 106 (11): 778.

https://doi.org/10.1182/blood.V106.11.778.778

Published: 2005

Journal Articles

Incidence of Febrile Neutropenia Is Low and Unrelated to Day 1 Neutrophil Count in Hodgkin’s Lymphoma Treated with ABVD.

Vikram K. Chand, MBBS, Justine Ritchie, PhD, Mary Shannon, RN, BSN, Brian K. Link, MD, James E. Wooldridge, MD

Blood (2004) 104 (11): 4590.

https://doi.org/10.1182/blood.V104.11.4590.4590

Published: 2004

Journal Articles

Cpg Oligodeoxynucleotide-Mediated Effects on B-Cell Chronic Lymphocytic Leukemia In Vitro Are Influenced by Cytogenetic Status and the Presence of Serum.

Bernd Jahrsdorfer, MD, Sue E. Blackwell, James E. Wooldridge, MD, Christiana M. Taylor, George J. Weiner, MD

Blood (2004) 104 (11): 4828.

https://doi.org/10.1182/blood.V104.11.4828.4828

Published: 2004

Journal Articles

FDG PET Scan Alone Better Predicts Progression Free Survival at 2 Years Compared to CT Imaging in Aggressive Histology Non-Hodgkin’s Lymphoma Following Initial Anthracycline-Based Chemotherapy.

Gregory A. Wiseman, MD, Malik E. Juweid, MD, Eric M. Rohren, MD, PhD, James E. Wooldridge, MD, Michael M. Graham, MD, PhD

Blood (2004) 104 (11): 3299.

https://doi.org/10.1182/blood.V104.11.3299.3299

Published: 2004

Journal Articles

Immunostimulatory Oligodeoxynucleotides Containing CpG Motifs Enhance the Efficacy of Monoclonal Antibody Therapy of Lymphoma

James E. Wooldridge, Zuhair Ballas, Arthur M. Krieg, George J. Weiner

Blood (1997) 89 (8): 2994–2998.

https://doi.org/10.1182/blood.V89.8.2994

Published: 1997

NARROW

Phase 1 Study of Tabalumab, a Human Anti-BAFF Antibody and Bortezomib in Patients with Previously-Treated Multiple Myeloma

Sustained Depletion of B-Cells by a Humanized, Fc-Engineered Anti-CD20 Antibody, AME-133v, in Patients with Relapsed Follicular Lymphoma

Phase I Study of a New Humanized Anti-CD20 Monoclonal Antibody (LY2469298) in Japanese Patients (pts) with Relapsed or Refractory Follicular Lymphoma (FL) Pretreated with Rituximab-Containing Regimen

Genetic Polymorphisms In Genes Involved In R-CHOP Metabolism and Event-Free and Overall Survival In Diffuse Large B-Cell Lymphoma

A Phase I Safety Study of Enzastaurin Plus Bortezomib in the Treatment of Relapsed or Refractory Multiple Myeloma.

Enzastaurin in Previously Treated Waldenstrom's Macroglobulinemia: An Open-Label, Multicenter, Phase II Study.

Oral Tipifarnib (R115777) Has Single Agent Anti-Tumor Activity in Patients with Relapsed Aggressive Non-Hodgkin Lymphoma (NHL): Results of a Phase II Trial in the University of Iowa/Mayo Clinic Lymphoma SPORE (CA97274).

IL-21 Plus CpG ODN Induces Granzyme B-Dependent Induction of Apoptosis in CD5-Positive B Cells Including B-CLL Cells.

B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation

Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab

Anti-CD20 Monoclonal Antibody (mAb) with Enhanced Affinity for CD16 Activates NK Cells at Lower Concentrations and More Effectively Than Rituximab ®.

IL-21 and CpG ODN Are Synergistic in Their Ability To Induce Apoptosis of Chronic Lymphocytic Leukemia (CLL) Cells and Benign B1 Cells.

A Polymorphism in the C1qA Component of Complement Correlates with Prolonged Complete Remission Following Rituximab Therapy of Follicular Lymphoma.

Incidence of Febrile Neutropenia Is Low and Unrelated to Day 1 Neutrophil Count in Hodgkin’s Lymphoma Treated with ABVD.

Cpg Oligodeoxynucleotide-Mediated Effects on B-Cell Chronic Lymphocytic Leukemia In Vitro Are Influenced by Cytogenetic Status and the Presence of Serum.

FDG PET Scan Alone Better Predicts Progression Free Survival at 2 Years Compared to CT Imaging in Aggressive Histology Non-Hodgkin’s Lymphoma Following Initial Anthracycline-Based Chemotherapy.

Immunostimulatory Oligodeoxynucleotides Containing CpG Motifs Enhance the Efficacy of Monoclonal Antibody Therapy of Lymphoma

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American Society of Hematology

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