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Journal Articles

PTPN11 mutations and Outcomes in Adult Patients with Acute Myeloid Leukemia

Klaus H. Metzeler, MD, Maja Rothenberg-Thurley, PhD, Dennis Görlich, PhD, Maria Cristina Sauerland, Annika Maria Dufour, PhD, Stephanie Schneider, PhD, Marion Subklewe, MD, Jan Braess, MD, Bernhard J. Wörmann, MD, Wolfgang E. Berdel, Prof., MD, Utz Krug, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-137487

Published: 2020

Journal Articles

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Sebastian Vosberg, Paul Kerbs, MSc, Vindi Jurinovic, MSc, Klaus H. Metzeler, MD, Susanne Amler, PhD, Cristina Sauerland, Dennis Görlich, PhD, Wolfgang E. Berdel, MD, Jan Braess, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 2715.

https://doi.org/10.1182/blood-2019-130047

Published: 2019

Journal Articles

Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification

Diego Chacon, PhD, Ali Braytee, PhD, Yizhou Huang, PhD, Julie Thoms, PhD, Shruthi Subramanian, BSc, Maria Cristina Sauerland, Stefan K. Bohlander, MD, Jan Braess, MD, Bernhard J. Wörmann, MD, Wolfgang E. Berdel, MD, Wolfgang Hiddemann, MD PhD, Bogdan Gabrys, PhD, Klaus H. Metzeler, MD, Tobias Herold, MD, John Pimanda, MBBS, PhD, Dominik Beck, PhD

Blood (2019) 134 (Supplement_1): 1397.

https://doi.org/10.1182/blood-2019-129519

Published: 2019

Journal Articles

Outcome of Patients with Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Beyond First Complete Remission (CR1)

Georg Evers, MD, Dietrich W. Beelen, Jan Braess, MD, Cristina Sauerland, Hans-Jochem Kolb, MD, Albrecht Reichle, MD, Ernst Holler, MD, Rainer Schwerdtfeger, MD, Renate Arnold, MD, Christoph Scheid, MD, Utz Krug, MD, Carsten Müller-Tidow, MD, Christoph Schliemann, MD, Jan-Henrik Mikesch, MD, Georg Lenz, Bernhard J. Wörmann, MD, Wolfgang Hiddemann, Wolfgang E. Berdel, MD, Matthias Stelljes, MD

Blood (2018) 132 (Supplement 1): 4649.

https://doi.org/10.1182/blood-2018-99-116964

Published: 2018

Journal Articles

NPM1 Variant Allele Frequency and Outcomes in AML

Blood (2018) 132 (Supplement 1): 1486.

https://doi.org/10.1182/blood-2018-99-112549

Published: 2018

Journal Articles

Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients

Katrin Reiter, MSc, Max Hubmann, MD, Egor Harin, Sebastian Vosberg, Kathrin Bräundl, Bianka Ksienzyk, Stephanie Schneider, PhD, Annika Maria Dufour, PhD, Evelyn Zellmeier, Stefan K. Bohlander, MD, Christina Sauerland, Dipl.-Math, Wolfgang E Berdel, MD, Bernhard J Wörmann, MD, Thomas Büchner, MD, Jan Braess, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD

Blood (2016) 128 (22): 1682.

https://doi.org/10.1182/blood.V128.22.1682.1682

Published: 2016

Journal Articles

Hemophagocytic Lymphohistiocytosis in Adults (aHLH): Results from the German HLH Registry

Sebastian Birndt, Thomas Schenk, MD, Frank M. Brunkhorst, MD, Georg Maschmeyer, MD, Frank Rothmann, MD, Thomas Weber, MD, Markus Müller, MD, Jens P. Panse, MD, Roland Schroers, MD, Jan Braess, MD, Norbert Frickhofen, MD, Gritta Janka, MD PhD, Kai Lehmberg, MD, Andreas Hochhaus, MD, Thomas Ernst, MD, Paul La Rosée, MD

Blood (2016) 128 (22): 2523.

https://doi.org/10.1182/blood.V128.22.2523.2523

Published: 2016

Journal Articles

DNMT3A Mutations Associate with Shorter Survival and Modulate the Prognostic Impact of Mutated NPM1: an Analysis Based on Comprehensive Mutational Screening of 660 AML Patients Treated on German AML Cooperative Group (AMLCG) Trials

Blood (2015) 126 (23): 3815.

https://doi.org/10.1182/blood.V126.23.3815.3815

Published: 2015

Journal Articles

Targeted, Deep Sequencing of Adult AML Patients Treated on the AMLCG-2008 Trial Detects Clonal Heterogeneity in 52% of Patients at Initial Diagnosis and Reveals Patterns of Clonal Evolution

Maja Rothenberg-Thurley, PhD, Stephanie Schneider, Dr. rer. nat., Tobias Herold, MD, Nikola P Konstandin, Annika Dufour, PhD, Kathrin Bräundl, Bianka Ksienzyk, Evelyn Zellmeier, Philipp A Greif, MD, Michael Fiegl, MD, Marion S. Subklewe, MD, Stefan K Bohlander, MD, Wolfgang Hiddemann, MD, Jan Braess, MD, Karsten Spiekermann, MD, Klaus H. Metzeler, MD

Blood (2014) 124 (21): 697.

https://doi.org/10.1182/blood.V124.21.697.697

Published: 2014

Journal Articles

Genetic Characterization of Patients with Monoallelic and Biallelic CEBPA Mutations Using a Targeted Sequencing Approach Reveals Differences in the Spectrum of Cooperating Mutations

Nikola P Konstandin, Klaus H. Metzeler, MD, Annika Dufour, PhD, Philipp A Greif, MD, Tobias Herold, MD, Bianka Ksienzyk, Stephanie Schneider, Dr. rer. nat., Wolfgang E Berdel, MD, Thomas Büchner, MD, Bernhard J. Woermann, MD, Cristina Sauerland, MSc, Jan Braess, MD, Wolfgang Hiddemann, MD, Stefan K Bohlander, MD, Karsten Spiekermann, MD

Blood (2014) 124 (21): 2385.

https://doi.org/10.1182/blood.V124.21.2385.2385

Published: 2014

Journal Articles

A Combined Molecular and Clinical Prognostic Index For Relapse and Survival In Cytogenetically Normal AML (PINA)

Blood (2013) 122 (21): 1303.

https://doi.org/10.1182/blood.V122.21.1303.1303

Published: 2013

Journal Articles

Coinhibitory Expression Profiling of AML Blasts Identifies HVEM as Prognostic Marker in AML

Felix S Lichtenegger, MD, Isabell Kondla, Michael Krempasky, Anna L Weber, Stephanie Schneider, PhD, Karsten Spiekermann, MD, Jan Braess, MD, Wolfgang Hiddemann, M.D., Marion Subklewe, MD

Blood (2013) 122 (21): 1359.

https://doi.org/10.1182/blood.V122.21.1359.1359

Published: 2013

Journal Articles

Acute Myeloid Leukemia: The Outcome Is Determined By Age, Genetic Group, White Blood Cell Count, Lactate Dehydrogenase, Rather Than By Chemotherapy Intensity

Blood (2013) 122 (21): 1447.

https://doi.org/10.1182/blood.V122.21.1447.1447

Published: 2013

Journal Articles

High Efficacy and Significantly Shortened Neutropenia Of Dose-Dense S-HAM As Compared To Standard Double Induction: First Results Of a Prospective Randomized Trial (AML-CG 2008)

Jan Braess, MD, Karl-Anton Kreuzer, Karsten Spiekermann, PhD, Hans Walter Lindemann, MD, Eva Lengfelder, MD, Ullrich Graeven, Peter Staib, MD, Wolf-Dieter Ludwig, Harald Biersack, Yon-Dschun Ko, MD, Michael J. Uppenkamp, Stefan Korsten, Maike De Wit, Rudolf Peceny, MD, Tobias Gaska, MD, Xaver Schiel, Dirk M Behringer, MD, Michael G. Kiehl, MD, PhD, Bettina Zinngrebe, Gerald Meckenstock, Eva Roemer, Dirk Medgenberg, Ernst Spaeth-Schwalbe, MD, Birgit Braess, MD, Gero Massenkeil, MD, Heidrun Hindahl, Guido Trenn, Rainer Schwerdtfeger, MD, Susanne Amler, MSc, Cristina Sauerland, MSc, Andreas Faldum, MD, Michael Unterhalt, M.D. Ph.D., Stefan K. Bohlander, MD, Stephanie Schneider, PhD, Annika Dufour, PhD, Christian Buske, MD, Michael Fiegl, MD, Marion Subklewe, MD, Anja Baumgartner, PhD, Bernhard J. Woermann, MD, Dietrich Beelen, MD, Wolfgang Hiddemann, MD

Blood (2013) 122 (21): 619.

https://doi.org/10.1182/blood.V122.21.619.619

Published: 2013

Journal Articles

Allogeneic Stem Cell Transplantation Versus Conventional Postremission Therapy for Acute Myeloid Leukemia in First Complete Remission: A Matched Pairs Analysis

Blood (2012) 120 (21): 1974.

https://doi.org/10.1182/blood.V120.21.1974.1974

Published: 2012

Journal Articles

Exome Sequencing Identifies Recurring FLT3 N676K Mutations in Core Binding Factor Leukemia

Sabrina Opatz, Harald Polzer, Tobias Herold, MD, Nikola P Konstandin, Bianka Ksienzyk, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Karl Peter Hopfner, PhD, Purvi M. Kakadia, PhD, Stephanie Schneider, PhD, Annika Dufour, PhD, Jan Braess, MD, Michael Heuser, MD, Wolfgang Hiddemann, MD, PhD, Karsten Spiekermann, MD, Stefan K Bohlander, MD, Philipp A Greif, MD

Blood (2012) 120 (21): 404.

https://doi.org/10.1182/blood.V120.21.404.404

Published: 2012

Journal Articles

High Frequency of GATA2 Mutations in Cytogenetically Normal Acute Myeloid Leukemia with Biallelic CEBPA Mutations Identified by Exome Sequencing

Blood (2011) 118 (21): 72.

https://doi.org/10.1182/blood.V118.21.72.72

Published: 2011

Journal Articles

A Combined Score of Minimal Residual Disease (MRD) Assessment by Flow Cytometry, Cytogenetic and Molecular Markers As Well As Age Predicts Outcome and Can Potentially Guide MRD-Based Therapy in Acute Myeloid Leukemia

Thomas Köhnke, MD, Daniela Sauter, MD, Katharina Ringel, Jan Braess, MD, Wolfgang Hiddemann, PhD, Karsten Spiekermann, MD, Marion Subklewe, MD

Blood (2011) 118 (21): 934.

https://doi.org/10.1182/blood.V118.21.934.934

Published: 2011

Journal Articles

Costimulatory Expression Profiling of AML Blasts Identifies Surface Markers with High Correlation to Isolated NPM1 Mutation

Felix S Lichtenegger, MD, Michael Krempasky, Karsten Spiekermann, MD, Jan Braess, MD, Wolfgang Hiddemann, PhD, Marion Subklewe, MD

Blood (2011) 118 (21): 2511.

https://doi.org/10.1182/blood.V118.21.2511.2511

Published: 2011

Journal Articles

Composition of PBMC Population and Functionality of T- and NK-Cells in AML Patients Receiving Cytotoxic Maintenance Therapy,

Felix S Lichtenegger, MD, Robin Lorenz, Patrick Palluch, Ulrich Hoffmueller, MBA, PhD, Jan Braess, MD, Wolfgang Hiddemann, PhD, Barbara Beck, PhD, Marion Subklewe, MD

Blood (2011) 118 (21): 3601.

https://doi.org/10.1182/blood.V118.21.3601.3601

Published: 2011

NARROW

PTPN11 mutations and Outcomes in Adult Patients with Acute Myeloid Leukemia

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification

Outcome of Patients with Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Beyond First Complete Remission (CR1)

NPM1 Variant Allele Frequency and Outcomes in AML

Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients

Hemophagocytic Lymphohistiocytosis in Adults (aHLH): Results from the German HLH Registry

DNMT3A Mutations Associate with Shorter Survival and Modulate the Prognostic Impact of Mutated NPM1: an Analysis Based on Comprehensive Mutational Screening of 660 AML Patients Treated on German AML Cooperative Group (AMLCG) Trials

Targeted, Deep Sequencing of Adult AML Patients Treated on the AMLCG-2008 Trial Detects Clonal Heterogeneity in 52% of Patients at Initial Diagnosis and Reveals Patterns of Clonal Evolution

Genetic Characterization of Patients with Monoallelic and Biallelic CEBPA Mutations Using a Targeted Sequencing Approach Reveals Differences in the Spectrum of Cooperating Mutations

A Combined Molecular and Clinical Prognostic Index For Relapse and Survival In Cytogenetically Normal AML (PINA)

Coinhibitory Expression Profiling of AML Blasts Identifies HVEM as Prognostic Marker in AML

Acute Myeloid Leukemia: The Outcome Is Determined By Age, Genetic Group, White Blood Cell Count, Lactate Dehydrogenase, Rather Than By Chemotherapy Intensity

High Efficacy and Significantly Shortened Neutropenia Of Dose-Dense S-HAM As Compared To Standard Double Induction: First Results Of a Prospective Randomized Trial (AML-CG 2008)

Allogeneic Stem Cell Transplantation Versus Conventional Postremission Therapy for Acute Myeloid Leukemia in First Complete Remission: A Matched Pairs Analysis

Exome Sequencing Identifies Recurring FLT3 N676K Mutations in Core Binding Factor Leukemia

High Frequency of GATA2 Mutations in Cytogenetically Normal Acute Myeloid Leukemia with Biallelic CEBPA Mutations Identified by Exome Sequencing

A Combined Score of Minimal Residual Disease (MRD) Assessment by Flow Cytometry, Cytogenetic and Molecular Markers As Well As Age Predicts Outcome and Can Potentially Guide MRD-Based Therapy in Acute Myeloid Leukemia

Costimulatory Expression Profiling of AML Blasts Identifies Surface Markers with High Correlation to Isolated NPM1 Mutation

Composition of PBMC Population and Functionality of T- and NK-Cells in AML Patients Receiving Cytotoxic Maintenance Therapy,

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American Society of Hematology

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ASH Publications

American Society of Hematology

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