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Journal Articles

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

Sabrina Opatz, MD, Sebastian Vosberg, Bianka Ksienzyk, Sebastian Tschuri, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, Dr., Stephanie Schneider, PhD, Martin Neumann, Claudia D. Baldus, MD, Christian Thiede, MD, Jan Moritz Middeke, MD, Friedrich Stoelzel, Stefan K. Bohlander, MD, Karsten Spiekermann, MD, Wolfgang Hiddemann, PhD, Klaus H. Metzeler, MD, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2772.

https://doi.org/10.1182/blood-2018-99-115881

Published: 2018

Journal Articles

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse

Blood (2016) 128 (22): 288.

https://doi.org/10.1182/blood.V128.22.288.288

Published: 2016

Journal Articles

Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia

Luise Hartmann, MSc, Sebastian Vosberg, Klaus H. Metzeler, MD, Daniela Schumacher, Friederike Pastore, MD, Kathrin Bräundl, Evelyn Zellmeier, Bianka Ksienzyk, Nikola P Konstandin, PhD, Stephanie Schneider, PhD, Stefan Krebs, PhD, Alexander Graf, PhD, Helmut Blum, PhD, Martin Neumann, MD, Claudia D Baldus, MD, Stefan K. Bohlander, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD

Blood (2015) 126 (23): 690.

https://doi.org/10.1182/blood.V126.23.690.690

Published: 2015

Journal Articles

Acute Myeloid Leukemia in the Elderly Is Characterized By a Distinct Genetic Landscape

Patricia Silva, Martin Neumann, MD, Sebastian Vosberg, Cornelia Schlee, Konstandina Isaakidis, Michael P Schroeder, Jutta Ortiz-Tánchez, Lars R. Fransecky, Teresa Hartung, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Gerhard Ehninger, Hubert Serve, MD, Wolfgang E Berdel, MD, Philipp A. Greif, Christoph Röllig, MD, Claudia D Baldus, MD

Blood (2015) 126 (23): 804.

https://doi.org/10.1182/blood.V126.23.804.804

Published: 2015

Journal Articles

Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data

Sebastian Vosberg, Luise Hartmann, MSc, Stephanie Schneider, PhD, Klaus H. Metzeler, MD, Bianka Ksienzyk, Kathrin Bräundl, Martin Neumann, MD, Claudia D Baldus, MD, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Karsten Spiekermann, MD, Stefan K. Bohlander, MD, Ulrich Mansmann, PhD, Philipp A. Greif, MD

Blood (2015) 126 (23): 3859.

https://doi.org/10.1182/blood.V126.23.3859.3859

Published: 2015

Journal Articles

Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control

Martin Neumann, MD, Sebastian Vosberg, Eva Kristin Von Der Heide, BSc, Cornelia Schlee, Jutta Ortiz Tanchez, Konstandina Isaakidis, Liliana H. Mochmann, BS,MSc, Lars R. Fransecky, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Philipp A. Greif, MD, Claudia D Baldus, MD

Blood (2015) 126 (23): 3843.

https://doi.org/10.1182/blood.V126.23.3843.3843

Published: 2015

Journal Articles

Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL

Lorenz Bastian, Martin Neumann, MD, Nicola Gökbuget, MD, Cornelia Schlee, Jutta Ortiz Tanchez, Sebastian Vosberg, Alva Rani James, Michael P Schroeder, Stefan Schwartz, MD, Dieter Hoelzer, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Jochen Hecht, Monika Brüggemann, Philipp A. Greif, Claudia D. Baldus, MD PhD

Blood (2015) 126 (23): 2625.

https://doi.org/10.1182/blood.V126.23.2625.2625

Published: 2015

Journal Articles

Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients

Eva von der Heide, Sebastian Vosberg, Martin Neumann, MD, Liliana H. Mochmann, MS, Alva Rani James, Jutta Ortiz Tanchez, Cornelia Schlee, MS, Konstandina Isaakidis, Marlene Luther, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Wolf-Karsten Hofmann, Philipp A Greif, MD, Claudia D Baldus, MD

Blood (2014) 124 (21): 699.

https://doi.org/10.1182/blood.V124.21.699.699

Published: 2014

Journal Articles

Analysis of the Tissue-Specific Expression Requirements and Identification of Cooperating Mutations for Leukemogenesis in an Inducible CALM/AF10 Knock-in Mouse Model

Sayantanee Dutta, Alexandre Krause, Sebastian Vosberg, Tobias Herold, MD, Bianca Ksienzyk, Leticia Quintanilla-Fend, Belay Tizazu, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Philipp A Greif, MD, Marlon Schneider, Maik Dahlhof, Karsten Spiekermann, MD, Ursula Zimber-Strobl, Eckhard Wolf, Stefan K Bohlander, MD

Blood (2014) 124 (21): 126.

https://doi.org/10.1182/blood.V124.21.126.126

Published: 2014

Journal Articles

The Mutatome of CBFB / MYH11- rearranged Acute Myeloid Leukemia (AML)

Sabrina Opatz, Klaus H Metzeler, MD, Tobias Herold, MD, Sebastian Vosberg, Kathrin Bräundl, Bianka Ksienzyk, Nikola P Konstandin, Christine Wang, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Stephanie Schneider, PhD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Stefan K Bohlander, MD, Philipp A Greif, MD

Blood (2014) 124 (21): 14.

https://doi.org/10.1182/blood.V124.21.14.14

Published: 2014

Journal Articles

Genetic Evolution of Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) during Therapy and Relapse: An Exome Sequencing Study of 47 Cases

Blood (2014) 124 (21): 17.

https://doi.org/10.1182/blood.V124.21.17.17

Published: 2014

Journal Articles

Copy Number Alteration (CNA) Analysis in Targeted Sequencing Data from Acute Myeloid Leukemia (AML) Patients with Chromosome 9q Deletion

Sebastian Vosberg, Tobias Herold, MD, Klaus H Metzeler, MD, Stephanie Schneider, PhD, Bianka Ksienzyk, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Karsten Spiekermann, MD, Stefan K Bohlander, MD, Ulrich Mansmann, PhD, Philipp A Greif, MD

Blood (2014) 124 (21): 1058.

https://doi.org/10.1182/blood.V124.21.1058.1058

Published: 2014

Journal Articles

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis

Blood (2014) 124 (8): 1304–1311.

https://doi.org/10.1182/blood-2013-12-540716

Published: 2014

Includes: Supplemental data

Journal Articles

FAT1 Expression and Mutation Status In Adult Acute Lymphoblastic Leukemia

Martin Neumann, MD, Marco Seehawer, MS, Cornelia Schlee, MS, Sebastian Vosberg, Sandra Heesch, MS, Eva von der Heide, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Nicola Gökbuget, MD, Stefan Schwartz, MD, Dieter Hoelzer, MD, Philipp A Greif, MD, Claudia D. Baldus, MD, PhD

Blood (2013) 122 (21): 2564.

https://doi.org/10.1182/blood.V122.21.2564.2564

Published: 2013

Journal Articles

Unbalanced Translocation t(5;17) Resulting In a TP53 Loss As Recurrent Aberration In Myelodysplastic Syndrome With Complex Karyotype

Gudrun Göhring, PD Dr. Med., Beate Vajen, Philipp A Greif, MD, Kathrin Thomay, Doris Steinemann, PhD, Sebastian Vosberg, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Stefan K. Bohlander, MD, Brigitte Schlegelberger, MD, PhD

Blood (2013) 122 (21): 4949.

https://doi.org/10.1182/blood.V122.21.4949.4949

Published: 2013

Journal Articles

Acute Myeloid Leukemia With Isolated Trisomy 13 Is a Genetically Homogenous Entity With a High Frequency Of Mutations In Genes Encoding Components Of The Splicing Machinery and Extremely Poor Prognosis

Blood (2013) 122 (21): 608.

https://doi.org/10.1182/blood.V122.21.608.608

Published: 2013

Journal Articles

Mutational Spectrum Of Adult T-ALL

Martin Neumann, MD, Sandra Heesch, MS, Sebastian Vosberg, Cornelia Schlee, MS, Stefan Schwartz, MD, Nicola Gökbuget, MD, Dieter Hoelzer, MD, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Monika Brüggemann, MD, Jochen Hecht, PhD, Stefan K. Bohlander, MD, Philipp A. Greif, MD, Claudia D. Baldus, MD, PhD

Blood (2013) 122 (21): 828.

https://doi.org/10.1182/blood.V122.21.828.828

Published: 2013

Journal Articles

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia

Blood (2013) 122 (10): 1761–1769.

https://doi.org/10.1182/blood-2013-01-476473

Published: 2013

Includes: Supplemental data

Journal Articles

Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

Martin Neumann, Sandra Heesch, Cornelia Schlee, Stefan Schwartz, Nicola Gökbuget, Dieter Hoelzer, Nikola P. Konstandin, Bianka Ksienzyk, Sebastian Vosberg, Alexander Graf, Stefan Krebs, Helmut Blum, Thorsten Raff, Monika Brüggemann, Wolf-Karsten Hofmann, Jochen Hecht, Stefan K. Bohlander, Philipp A. Greif, Claudia D. Baldus

Blood (2013) 121 (23): 4749–4752.

https://doi.org/10.1182/blood-2012-11-465138

Published: 2013

Includes: Supplemental data

Journal Articles

Exome Sequencing Identifies Recurring DNMT3A Mutations in Adult ETP-ALL

Martin Neumann, MD, Sandra Heesch, PhD, Cornelia Schlee, MS, Stefan Schwartz, MD, Nicola Goekbuget, MD, Dieter Hoelzer, MD, Nikola P Konstandin, Bianka Ksienzyk, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, PhD, Thorsten Raff, MD, Monika Brueggemann, Wolf-Karsten Hofmann, Stefan K Bohlander, MD, Philipp A Greif, MD, Claudia D Baldus

Blood (2012) 120 (21): 1377.

https://doi.org/10.1182/blood.V120.21.1377.1377

Published: 2012

NARROW

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse

Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia

Acute Myeloid Leukemia in the Elderly Is Characterized By a Distinct Genetic Landscape

Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data

Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control

Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL

Molecular Alterations in Bone Marrow Mesenchymal Stroma Cells of AML Patients

Analysis of the Tissue-Specific Expression Requirements and Identification of Cooperating Mutations for Leukemogenesis in an Inducible CALM/AF10 Knock-in Mouse Model

The Mutatome of CBFB / MYH11- rearranged Acute Myeloid Leukemia (AML)

Genetic Evolution of Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) during Therapy and Relapse: An Exome Sequencing Study of 47 Cases

Copy Number Alteration (CNA) Analysis in Targeted Sequencing Data from Acute Myeloid Leukemia (AML) Patients with Chromosome 9q Deletion

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis

FAT1 Expression and Mutation Status In Adult Acute Lymphoblastic Leukemia

Unbalanced Translocation t(5;17) Resulting In a TP53 Loss As Recurrent Aberration In Myelodysplastic Syndrome With Complex Karyotype

Acute Myeloid Leukemia With Isolated Trisomy 13 Is a Genetically Homogenous Entity With a High Frequency Of Mutations In Genes Encoding Components Of The Splicing Machinery and Extremely Poor Prognosis

Mutational Spectrum Of Adult T-ALL

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia

Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations

Exome Sequencing Identifies Recurring DNMT3A Mutations in Adult ETP-ALL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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