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Journal Articles

Genetic Determinants of Response to Guadecitabine (SGI-110) in AML

Patricia L. Kropf, MD, Woonbok Chung, PhD, Andrew D. Kelly, BA, Hagop M. Kantarjian, MD, Gail J. Roboz, Karen W.L. Yee, MD, Pietro Taverna, PhD, Sue Naim, Mohammad Azab, MD, Jaroslav Jelinek, MD PhD, Jean-Pierre J. Issa, MD

Blood (2016) 128 (22): 1680.

https://doi.org/10.1182/blood.V128.22.1680.1680

Published: 2016

Journal Articles

Improved Survival for MDS/CMML Patients Treated with the Combination of Decitabine (DAC) and Arsenic Trioxide (ATO) in a Phase II Adaptive Three Arm Randomization Study: DAC Alone Vs. DAC +/- Carboplatin or ATO

Patricia L. Kropf, MD, Raji Shameem, MD, Philip A. Pancari, MD, Henry Fung, MD, Lianchun Xiao, PhD, Xuelin Huang, PhD, Woonbok Chung, PhD, Hagop M. Kantarjian, MD, Jean-Pierre J. Issa, MD

Blood (2016) 128 (22): 3170.

https://doi.org/10.1182/blood.V128.22.3170.3170

Published: 2016

Journal Articles

Reactivation of the X-Chromosome Genes within PV Clone

Soo Jin Kim, MS, Jaroslav Jelinek, MD PhD, Jean-Pierre J Issa, MD, Josef T. Prchal, MD, Sabina Swierczek, PhD

Blood (2015) 126 (23): 4086.

https://doi.org/10.1182/blood.V126.23.4086.4086

Published: 2015

Journal Articles

Sequential Therapy with Allogeneic Transplant Followed by Low-Dose Azacitidine for CML Patients That Failed Multiple Tyrosine Kinase Inhibitors

Marcos De Lima, MD, Sairah Ahmed, MD, Elizabeth J Shpall, MD, Gabriela Rondon, MD, Julienne Chen, Glenda G Woodworth, RN, Alexandre Chiattone, MD, Diem Thuy Chu, PA, Uday R Popat, MD, Susanna R Campos, MD, Amin M Alousi, MD, Chitra M Hosing, MD, Simrit Parmar, MD, Partow Kebriaei, MD, Issa F. Khouri, MD, Jorge E. Cortes, Jean-Pierre J Issa, MD, Richard Champlin, MD

Blood (2011) 118 (21): 3106.

https://doi.org/10.1182/blood.V118.21.3106.3106

Published: 2011

Journal Articles

DNA Methylation and Gene Expression Analysis in a Phase II Randomized Study of Decitabine Vs. Decitabine Plus Valproic Acid in MDS and AML.

Ryan J Castoro, Noel J Raynal, Ph.D., Xuelin Huang, Ph.D., Carlos E. Bueso-Ramos, M.D., Ph.D, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, Jean-Pierre J Issa, MD

Blood (2009) 114 (22): 3808.

https://doi.org/10.1182/blood.V114.22.3808.3808

Published: 2009

Journal Articles

Digital Restriction Enzyme Analysis of Methylation (DREAM) by Next Generation Sequencing Yields High Resolution Maps of DNA Methylation.

Jaroslav Jelinek, MD, PhD, Shoudan Liang, PhD, Marcos R. H. Estecio, PhD, Rong He, Yue Lu, PhD, Louis S. Ramagli, PhD, Jean-Pierre J. Issa, MD

Blood (2009) 114 (22): 567.

https://doi.org/10.1182/blood.V114.22.567.567

Published: 2009

Journal Articles

Vorinostat in Combination with Decitabine for the Treatment of Relapsed or Newly Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS): A Phase I, Dose-Escalation Study.

Mark Kirschbaum, MD, Ivana Gojo, MD, Stuart L. Goldberg, MD, Lisa Kujawski, Ehab Atallah, Peter Marks, MD, PhD, Donna Di Gravio, Lisa Pyle, Syed Rizvi, Jean-Pierre J Issa, MD

Blood (2009) 114 (22): 2089.

https://doi.org/10.1182/blood.V114.22.2089.2089

Published: 2009

Journal Articles

Classifying Leukemias Based on Epigenetic Alterations.

Jaroslav Jelinek, MD, PhD, Marcos R.H. Estecio, PhD, Kimie Kondo, MS, Rong He, MS, Jiri Zavadil, PhD, Jean-Pierre J. Issa, MD

Blood (2007) 110 (11): 2123.

https://doi.org/10.1182/blood.V110.11.2123.2123

Published: 2007

Journal Articles

Aberrant CpG Island Methylation in AML Is Associated with Disease Progression and Relapse.

Heike Kroeger, MD, Jaroslav Jelinek, MD, PhD, Carlos E. Bueso-Ramos, MD, PhD, Jean-Pierre J. Issa, MD

Blood (2006) 108 (11): 564.

https://doi.org/10.1182/blood.V108.11.564.564

Published: 2006

Journal Articles

RPS19 and JAK2 Are Not Silenced by DNA Methylation in Diamond-Blackfan Anemia.

Jaroslav Jelinek, MD, PhD, Jean-Pierre J. Issa, MD, Rong He, MS, Radek Cmejla, PhD, Jana Cmejlova, PhD, Dagmar Pospisilova, MD PhD

Blood (2006) 108 (11): 1312.

https://doi.org/10.1182/blood.V108.11.1312.1312

Published: 2006

Journal Articles

Aberrant DNA Methylation in CML Is Associated with Disease Progression and Resistance to Imatinib Mesylate.

Jaroslav Jelinek, MD, PhD, Vazganush Gharibyan, Yasuhiro Oki, MD, Woonbok Chung, PhD, Lanlan Shen, MD PhD, Jorge E. Cortes, MD, Hagop M. Kantarjian, MD, Jean-Pierre J. Issa, MD

Blood (2006) 108 (11): 2192.

https://doi.org/10.1182/blood.V108.11.2192.2192

Published: 2006

Journal Articles

Distinct DNA Methylation Patterns of HOX Genes in Leukemia.

Amanda J. Saraf, Samantha F. Lau, Rong He, MS, Jean-Pierre J. Issa, MD, Jaroslav Jelinek, MD, PhD

Blood (2006) 108 (11): 2238.

https://doi.org/10.1182/blood.V108.11.2238.2238

Published: 2006

Journal Articles

Methylation of Progesterone Receptor Promoter-Associated CpG Island in Polycythemia Vera and Related Myeloproliferative Disorders.

Jaroslav Jelinek, MD, PhD, Srdan Verstovsek, MD, Carlos E. Bueso-Ramos, M.D, PhD, Josef T. Prchal, MD, Jean-Pierre J. Issa, MD

Blood (2005) 106 (11): 3507.

https://doi.org/10.1182/blood.V106.11.3507.3507

Published: 2005

Journal Articles

CpG Island Methylation Is a Poor Prognostic Factors in Myelodysplastic Syndrome Patients and Is Reversed by Decitabine Therapy-Results of a Phase III Randomized Study.

Lanlan Shen, MD, PhD, Hagop Kantarjian, MD, Hussain Saba, MD, E. Lin, Don Berry, Saira Ahmed, Jaroslav Jelinek, MD, Jean-Pierre J. Issa, MD

Blood (2005) 106 (11): 790.

https://doi.org/10.1182/blood.V106.11.790.790

Published: 2005

NARROW

Genetic Determinants of Response to Guadecitabine (SGI-110) in AML

Improved Survival for MDS/CMML Patients Treated with the Combination of Decitabine (DAC) and Arsenic Trioxide (ATO) in a Phase II Adaptive Three Arm Randomization Study: DAC Alone Vs. DAC +/- Carboplatin or ATO

Reactivation of the X-Chromosome Genes within PV Clone

Sequential Therapy with Allogeneic Transplant Followed by Low-Dose Azacitidine for CML Patients That Failed Multiple Tyrosine Kinase Inhibitors

DNA Methylation and Gene Expression Analysis in a Phase II Randomized Study of Decitabine Vs. Decitabine Plus Valproic Acid in MDS and AML.

Digital Restriction Enzyme Analysis of Methylation (DREAM) by Next Generation Sequencing Yields High Resolution Maps of DNA Methylation.

Vorinostat in Combination with Decitabine for the Treatment of Relapsed or Newly Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS): A Phase I, Dose-Escalation Study.

Classifying Leukemias Based on Epigenetic Alterations.

Aberrant CpG Island Methylation in AML Is Associated with Disease Progression and Relapse.

RPS19 and JAK2 Are Not Silenced by DNA Methylation in Diamond-Blackfan Anemia.

Aberrant DNA Methylation in CML Is Associated with Disease Progression and Resistance to Imatinib Mesylate.

Distinct DNA Methylation Patterns of HOX Genes in Leukemia.

Methylation of Progesterone Receptor Promoter-Associated CpG Island in Polycythemia Vera and Related Myeloproliferative Disorders.

CpG Island Methylation Is a Poor Prognostic Factors in Myelodysplastic Syndrome Patients and Is Reversed by Decitabine Therapy-Results of a Phase III Randomized Study.

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American Society of Hematology

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American Society of Hematology

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