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Journal Articles

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Blood (2019) 134 (Supplement_1): 1692.

https://doi.org/10.1182/blood-2019-128573

Published: 2019

Journal Articles

Germ line tissues for optimal detection of somatic variants in myelodysplastic syndromes

Eric Padron, Markus C. Ball, Jamie K. Teer, Jeffrey S. Painter, Sean J. Yoder, Chaomei Zhang, Ling Zhang, Lynn C. Moscinski, Dana E. Rollison, Steven D. Gore, Rafael Bejar, Matthew J. Walter, Mikkael A. Sekeres, Rami S. Komrokji, Pearlie K. Epling-Burnette

Blood (2018) 131 (21): 2402–2405.

https://doi.org/10.1182/blood-2018-01-827881

Published: 2018

Includes: Supplemental data

Journal Articles

Germline Tissues and DNA Sequencing Analysis Methods for Optimal Somatic Variant Detection in Myelodysplastic Syndrome (MDS)

Eric Padron, MD, Jamie Teer, PhD, Markus Christian Ball, PhD, Jeffrey S Painter, BS, Rami S. Komrokji, MD, Ling Zhang, MD, Lynn C. Moscinski, MD, Mikkael A. Sekeres, MD MS, Steven D. Gore, MD, Rafael Bejar, MD PhD, Matthew J. Walter, MD, Pearlie Epling-Burnette, PhD PharmD

Blood (2017) 130 (Supplement 1): 1685.

https://doi.org/10.1182/blood.V130.Suppl_1.1685.1685

Published: 2017

Journal Articles

ETV6 and signaling gene mutations are associated with secondary transformation of myelodysplastic syndromes to chronic myelomonocytic leukemia

Eric Padron, Sean Yoder, Sateesh Kunigal, Tania Mesa, Jamie K. Teer, Najla Al Ali, Mikkael A. Sekeres, Jeffrey S. Painter, Ling Zhang, Jeffrey Lancet, Jaroslaw P. Maciejewski, Pearlie K. Epling-Burnette, Eduardo Sotomayor, Rami S. Komrokji, Alan F. List

Blood (2014) 123 (23): 3675–3677.

https://doi.org/10.1182/blood-2014-03-562637

Published: 2014

Includes: Supplemental data

Journal Articles

SRSF2 Mutations Impair Nuclear Aggregation and Represent a Novel Mechanism Of Spliceosomal Dysregulation In CMML

Eric Padron, MD, Sateesh Kunigal, PhD, Xiaoyi Ren, Jeffrey S. Painter, B.S., Rainer Metcalf, Joseph Johnson, Ling Zhang, MD, Jeffrey E Lancet, MD, Rami S Komrokji, MD, Kenyon Daniels, PhD, Alan List, MD, Pearlie K Epling-Burnette, PhD

Blood (2013) 122 (21): 260.

https://doi.org/10.1182/blood.V122.21.260.260

Published: 2013

Journal Articles

GM-CSF–dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia

Eric Padron, Jeffrey S. Painter, Sateesh Kunigal, Adam W. Mailloux, Kathy McGraw, Jessica M. McDaniel, Eunhee Kim, Christopher Bebbington, Mark Baer, Geoffrey Yarranton, Jeffrey Lancet, Rami S. Komrokji, Omar Abdel-Wahab, Alan F. List, Pearlie K. Epling-Burnette

Blood (2013) 121 (25): 5068–5077.

https://doi.org/10.1182/blood-2012-10-460170

Published: 2013

Includes: Supplemental data

Journal Articles

Preclinical Characterization of KB003, a Novel Humaneered™ Monoclonal Anti-GM-CSF Antibody, Demonstrates That the GM-CSF Signaling Axis Is a Therapeutic Target in Chronic Myelomonocytic Leukemia (CMML)

Eric Padron, MD, Jeffrey S Painter, BS, Adam W Mailloux, PhD, Kathy L. McGraw, Jessica M. McDaniel, BS, Christopher Bebbington, DPhil., Mark Baer, PhD, Geoffrey Yarranton, PhD, Jeffrey E Lancet, MD, Rami S. Komrokji, MD, Alan F. List, MD, P.K. Epling-Burnette, PharmD, PhD

Blood (2012) 120 (21): 3793.

https://doi.org/10.1182/blood.V120.21.3793.3793

Published: 2012

Journal Articles

Increased Group B Killer Cell Immunoglobulin-Like Receptor (KIR) Haplotypes with Mismatched MHC Class I and Altered NK Repertoire Distribution in Bone Marrow Failure Syndromes

Jeffrey S Painter, BS, Jong Park, PhD, Michael J Clemente, Christine L. O'Keefe, PhD, Sheng Wei, MD, Jaroslaw P. Maciejewski, MD, PhD, Ron Paquette, MD, PhD, Thomas P. Loughran, Jr., M.D., Alan F. List, MD, Pearlie K Epling-Burnette, PhD

Blood (2011) 118 (21): 2412.

https://doi.org/10.1182/blood.V118.21.2412.2412

Published: 2011

Journal Articles

Human Telomerase Reverse Transcriptase (hTERT) Deficiency in Myelodysplastic Syndrome (MDS) Demonstrates Mechanistic Linkage to Aplastic Anemia Pathophysiology

Lili Yang, PhD, Adam W Mailloux, PhD, Dana E Rollison, PhD, Jong Park, PhD, Jeffrey S. Painter, B.S., Rami S. Komrokji, MD, Jaroslaw P Maciejewski, MD, PhD, Ronald Paquette, MD, PhD, Thomas P. Loughran, Jr., MD, Sheng Wei, MD, Alan F. List, MD, Pearlie K Epling-Burnette, Pharm D, PhD

Blood (2011) 118 (21): 791.

https://doi.org/10.1182/blood.V118.21.791.791

Published: 2011

Journal Articles

GM-CSF Signaling Abnormalities in Chronic Myelomonocytic Leukemia

Eric Padron, MD, Jeffrey S. Painter, B.S., Adam W Mailloux, PhD, Jessica M. McDaniel, BS, Christopher Bebbington, DPhil., Mark Baer, PhD, Rami S. Komrokji, MD, Alan F. List, MD, Pearlie K Epling-Burnette, Pharm D, PhD

Blood (2011) 118 (21): 1713.

https://doi.org/10.1182/blood.V118.21.1713.1713

Published: 2011

Journal Articles

Importance of T-Cell Proliferative Stress In Myelodysplastic Syndrome

Lili Yang, PhD, Amber Schmidt, Undergraduate, Rami Komrokji, MD, Jeffrey S. Painter, BS, Ashley Cole, Alan F. List, MD, Dana E. Rollison, PhD, P.K. Epling-Burnette, PharmD, PhD

Blood (2010) 116 (21): 2939.

https://doi.org/10.1182/blood.V116.21.2939.2939

Published: 2010

Journal Articles

Phase 2 Multicenter Trial of Rabbit Anti-Thymocyte Serotherapy In Myelodysplastic Syndrome: Rate of Hematological Improvement Associated with Pre-Treatment Disease Duration

P.K. Epling-Burnette, PharmD, PhD, Rami S. Komrokji, MD, Jaroslaw P Maciejewski, MD, PhD, FACP, Mikkael A. Sekeres, MD, MS, Ronald Paquette, MD, Sheng Wei, MD, Jeffrey S Painter, BS, Fanqi Bai, MD, William J Fulp, Jennifer Paleveda-Pena, Dung-Tsa Chen, PhD, Alan F. List, MD

Blood (2010) 116 (21): 602.

https://doi.org/10.1182/blood.V116.21.602.602

Published: 2010

Journal Articles

Autoproliferation Contributes to Clonal Expansion and Changes In Cellular Topography In T Cell Large Granular Lymphocyte (LGL) Leukemia

JianXiang Zou, MD, Jeffrey S Painter, BS, Fanqi Bai, MD, Lubomir Sokol, MD, PhD, Thomas P. Loughran, Jr., MD, P.K. Epling-Burnette, PharmD, PhD

Blood (2010) 116 (21): 1373.

https://doi.org/10.1182/blood.V116.21.1373.1373

Published: 2010

Journal Articles

Positive Impact of T-Cell Clonal Expansion On Overall Survival in Patients with High-Risk Myelodysplastic Syndromes.

Amber Schmidt, Rami S. Komrokji, MD, Jeffrey S. Painter, B.S., Dana E Rollison, PhD, Ling Zhang, MD, Lynn C. Moscinski, MD, Alan F List, MD, P.K. Epling-Burnette, PhD

Blood (2009) 114 (22): 1572.

https://doi.org/10.1182/blood.V114.22.1572.1572

Published: 2009

Journal Articles

Functional T Cell Array Reveals Pre-Treatment Expanded Terminal Effector Memory Response Is Associated with Lenalidomide Failure in Non-Del(5q) Myelodysplastic Syndrome.

P.K. Epling-Burnette, PhD, JianXiang Zou, MD, Jeffrey S. Painter, B.S., Dung-Tsa Chen, Jimmy Fulp, Rami S. Komrokji, MD, Sheng Wei, MD, Alan F List, MD

Blood (2009) 114 (22): 1759.

https://doi.org/10.1182/blood.V114.22.1759.1759

Published: 2009

Journal Articles

Pathogenetic Role of Impaired Telomere Repair in Myelodysplastic Syndrome.

P.K. Epling-Burnette, PhD, Alan F List, MD, Justine Clark, MS, Ji-Hyun Lee, Kristen A. Jonathan, William Fulp, Xiaohong Li, Weipeng Zheng, Jeffrey S. Painter, B.S., JianXiang Zou, MD, Rami S. Komrokji, MD, Sheng Wei, MD, Jong Park, Amber Schmidt, Undergraduate, student, Chiharu Sugimori, MD, Ashley Cole, Dana E Rollison, PhD

Blood (2009) 114 (22): 2777.

https://doi.org/10.1182/blood.V114.22.2777.2777

Published: 2009

Journal Articles

A critical role for DAP10 and DAP12 in CD8 + T cell–mediated tissue damage in large granular lymphocyte leukemia

Xianghong Chen, Fanqi Bai, Lubomir Sokol, Junmin Zhou, Amy Ren, Jeffrey S. Painter, Jinhong Liu, David A. Sallman, Y. Ann Chen, Jeffrey A. Yoder, Julie Y. Djeu, Thomas P. Loughran, Pearlie K. Epling-Burnette, Sheng Wei

Blood (2009) 113 (14): 3226–3234.

https://doi.org/10.1182/blood-2008-07-168245

Published: 2009

Journal Articles

Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling

P. K. Epling-Burnette, Lubomir Sokol, Xianhong Chen, Fanqi Bai, Junmin Zhou, Michelle A. Blaskovich, JianXiang Zou, Jeffrey S. Painter, Todd D. Edwards, Lynn Moscinski, Jeffrey A. Yoder, Julie Y. Djeu, Said Sebti, Thomas P. Loughran, Jr, Sheng Wei

Blood (2008) 112 (12): 4694–4698.

https://doi.org/10.1182/blood-2008-02-136382

Published: 2008

Includes: Supplemental data

Journal Articles

Genetic Disparities in Killer Cell Immunoglobulin-Like Receptors (KIR) and MHC Class I in Bone Marrow Failure Syndromes

P.K. Epling-Burnette, PhD, Jeffrey S. Painter, BS, H.-S. Lee, PhD, Jong Park, Michael Clemente, MS, Christine O’Keefe, MD, Tie-Ying Wei, BS, Sheng Wei, MD, Jaroslaw Maciejewski, Thomas P. Loughran, Jr., MD, Ron Paquette, MD, Alan F. List, MD, Julie Y Djeu, PhD

Blood (2008) 112 (11): 4121.

https://doi.org/10.1182/blood.V112.11.4121.4121

Published: 2008

Journal Articles

A Comprehensive Lymphocyte Analysis of Dasatinib Treated Chronic Myelogenous Leukemia Patients Reveals T-Cell Oligoclonality.

John J. Powers, B.S., Jeffrey S. Painter, B.S., Jason A Dubovsky, B.S., P.K. Epling-Burnette, PharmD, PhD, Javier Pinilla, MD, PhD

Blood (2008) 112 (11): 1114.

https://doi.org/10.1182/blood.V112.11.1114.1114

Published: 2008

NARROW

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Germ line tissues for optimal detection of somatic variants in myelodysplastic syndromes

Germline Tissues and DNA Sequencing Analysis Methods for Optimal Somatic Variant Detection in Myelodysplastic Syndrome (MDS)

ETV6 and signaling gene mutations are associated with secondary transformation of myelodysplastic syndromes to chronic myelomonocytic leukemia

SRSF2 Mutations Impair Nuclear Aggregation and Represent a Novel Mechanism Of Spliceosomal Dysregulation In CMML

GM-CSF–dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia

Preclinical Characterization of KB003, a Novel Humaneered™ Monoclonal Anti-GM-CSF Antibody, Demonstrates That the GM-CSF Signaling Axis Is a Therapeutic Target in Chronic Myelomonocytic Leukemia (CMML)

Increased Group B Killer Cell Immunoglobulin-Like Receptor (KIR) Haplotypes with Mismatched MHC Class I and Altered NK Repertoire Distribution in Bone Marrow Failure Syndromes

Human Telomerase Reverse Transcriptase (hTERT) Deficiency in Myelodysplastic Syndrome (MDS) Demonstrates Mechanistic Linkage to Aplastic Anemia Pathophysiology

GM-CSF Signaling Abnormalities in Chronic Myelomonocytic Leukemia

Importance of T-Cell Proliferative Stress In Myelodysplastic Syndrome

Phase 2 Multicenter Trial of Rabbit Anti-Thymocyte Serotherapy In Myelodysplastic Syndrome: Rate of Hematological Improvement Associated with Pre-Treatment Disease Duration

Autoproliferation Contributes to Clonal Expansion and Changes In Cellular Topography In T Cell Large Granular Lymphocyte (LGL) Leukemia

Positive Impact of T-Cell Clonal Expansion On Overall Survival in Patients with High-Risk Myelodysplastic Syndromes.

Functional T Cell Array Reveals Pre-Treatment Expanded Terminal Effector Memory Response Is Associated with Lenalidomide Failure in Non-Del(5q) Myelodysplastic Syndrome.

Pathogenetic Role of Impaired Telomere Repair in Myelodysplastic Syndrome.

A critical role for DAP10 and DAP12 in CD8 + T cell–mediated tissue damage in large granular lymphocyte leukemia

Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling

Genetic Disparities in Killer Cell Immunoglobulin-Like Receptors (KIR) and MHC Class I in Bone Marrow Failure Syndromes

A Comprehensive Lymphocyte Analysis of Dasatinib Treated Chronic Myelogenous Leukemia Patients Reveals T-Cell Oligoclonality.

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American Society of Hematology

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