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Joanna Zabkiewicz, PhD
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Journal Articles

Results of a Phase 2 Trial of the Monocyte-Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) in Chronic Myelomonocytic Leukemia (CMML) — the UK Monocle Study

Steven Knapper, DM, Michael Dennis, MD, MRCP, FRCPath, Mark W Drummond, PhDMD, Robert K. Hills, MA, DPhil, MSc, Richard James Dillon, MA, PhD MRCP, FRCPath, Christopher Pocock, MD PhD, Dominic J. Culligan, Paresh Vyas, Daniel Wiseman, MB, ChB, Joanna Zabkiewicz, PhD, Marie Hodges, PhD MSc, Catherine Cargo, MB, FRCPath, Jan Taylor, PhD MSc, BSc, Laura Upton, Melissa Wright, David Bowen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1818.
https://doi.org/10.1182/blood-2018-99-110356
Published: 2018
Journal Articles

Extracellular Microvesicle Cytokines Secreted from Bone Marrow Mesenchymal Cells Mediate Proliferative and Survival Advantage in Acute Myeloid Leukaemia

Michelle Lazenby, BSc, Oliver G. Ottmann, MD, Keith Wilson, FRCPath, MRCP, MBBS, Caroline Alvares, MBBS, PhD, Joanna Zabkiewicz, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2744.
https://doi.org/10.1182/blood-2018-99-113342
Published: 2018
Journal Articles

Adipogeneis in the Bone Marrow Microenvironment Confers a Proliferative Advantage in Residual Leukaemic Cell Populations in Acute Myeloid Leukaemia after Allogeneic Stem Cell Transplantation

Felicity May, BSc, Caroline Alvares, MBBS, PhD, Oliver G. Ottmann, MD, Joanna Zabkiewicz, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2580.
https://doi.org/10.1182/blood-2018-99-114443
Published: 2018
Journal Articles

Bone Marrow Stromal Cells Mediate Adhesion Based Drug Resistance in Acute Myeloid Leukaemia through Reciprocal Feedback of the β-Catenin/CD44 Signalling Axis

Lihui Zhuang, PhD MSc, BSc, Richard Darley, PhD, Oliver G. Ottmann, MD, Joanna Zabkiewicz, PhD, Caroline Alvares, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2776.
https://doi.org/10.1182/blood-2018-99-113811
Published: 2018
Journal Articles

Axl/ Mer Inhibitor ONO-9330547 As a Novel Therapeutic Agent in a Stromal Co-Culture Model of Primary Acute Myeloid Leukaemia (AML)

Marie Gilmour, PhD, Anna Scholtz, Oliver G. Ottmann, MD, Robert K Hills, DPhil, Steven Knapper, Joanna Zabkiewicz, PhD
Journal: Blood
Blood (2016) 128 (22): 2754.
https://doi.org/10.1182/blood.V128.22.2754.2754
Published: 2016
Journal Articles

Pacritinib Suppresses Leukemic Outgrowth from FLT3-ITD Positive Stroma-Adherent Primary AML Cells

Ceri Marrin, MBBCh, Gareth Edwards, PhD, Steven Knapper, DM BMBCh, Alan K. Burnett, MDFRCP, Joanna Zabkiewicz, PhD, Caroline Alvares, MB BS PhD
Journal: Blood
Blood (2014) 124 (21): 270.
https://doi.org/10.1182/blood.V124.21.270.270
Published: 2014
Journal Articles

The Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) Shows Selective In Vitro Efficacy In Monocytoid-Lineage Acute Myeloid Leukaemia (AML)

Joanna Zabkiewicz, PhD, Marie Gilmour, Robert K. Hills, Elizabeth Bone, Alan Davidson, Alan K. Burnett, MD, Steven Knapper, MD
Journal: Blood
Blood (2013) 122 (21): 1297.
https://doi.org/10.1182/blood.V122.21.1297.1297
Published: 2013
Journal Articles

PDK1 Overexpression In Acute Myeloid Leukemia; Clinical Significance and Potential as a Therapeutic Target

Joanna Zabkiewicz, PhD, Lorna Pearn, Robert Hills, MA, MSc, DPhil, Rhys, Gareth Morgan, BSc, Alan Burnett, MD, Alex Tonks, PhD, Richard L Darley, PhD
Journal: Blood
Blood (2010) 116 (21): 2162.
https://doi.org/10.1182/blood.V116.21.2162.2162
Published: 2010