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John Schindler
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Journal Articles

Synergy of Sequential and Concurrent Administration of a Deglycosylated Ricin A Chain-Containing Combined Anti-CD19 and Anti-CD22 Immunotoxin (Combotox) and Cytarabine in a Murine Model of Advanced Acute Lymphoblastic Leukemia

Stefan K Barta, MD, MS, MRCP, Yiyu Zou, PhD, John Schindler, PhD, Tushar Bhagat, Victor Ghetie, PhD, Ellen S Vitetta, MS, PhD, Amit Verma, MD
Journal: Blood
Blood (2011) 118 (21): 1526.
https://doi.org/10.1182/blood.V118.21.1526.1526
Published: 2011
Journal Articles

CASPALLO: Phase I Clinical Trial of Allodepleted T Cells Transduced with Inducible Caspase 9 Suicide Gene After Haploidentical Stem Cell Transplantation

Antonio Di Stasi, MD, Siok K Tey, MD, Yuriko Fujita, MD, Russell Cruz, MD, Alana Kennedy-Nasser, MD, Caridad Martinez, MD, Stephen M Gottschalk, MD, Karin Straathof, MD, Enli Liu, April Durett, Bambi J Grilley, Hao Liu, PhD, Barbara Savoldo, MD, Yvon Eric, PhD, Teresita Lopez, Oumar Diouf, Adrian P. Gee, PhD, John Schindler, PhD, Catherine M Bollard, MD, Robert A Krance, MD, David M Spencer, PhD, Cliona M Rooney, PhD, Helen E Heslop, MD, Gianpietro Dotti, MD, Malcolm K Brenner, MB, PhD, FRCP, FRCPath
Journal: Blood
Blood (2010) 116 (21): 559.
https://doi.org/10.1182/blood.V116.21.559.559
Published: 2010
Journal Articles

Reconstitution of FOXP3 + regulatory T cells (T regs ) after CD25-depleted allotransplantion in elderly patients and association with acute graft-versus-host disease

Stephan Mielke, Katayoun Rezvani, Bipin N. Savani, Raquel Nunes, Agnes S. M. Yong, John Schindler, Roger Kurlander, Victor Ghetie, Elizabeth J. Read, Scott R. Solomon, Ellen S. Vitetta, A. John Barrett
Journal: Blood
Blood (2007) 110 (5): 1689–1697.
https://doi.org/10.1182/blood-2007-03-079160
Published: 2007
Journal Articles

Selective Depletion of CD25+ Host-Reactive Donor Lymphocytes from Allografts Preserves a CD25− CD4+foxp3+ Fraction of T Cells and Thereby Provides a Source for Efficient Reconstitution of Regulatory T Cells and Additional GVHD Control.

Stephan Mielke, MD, Katayoun Rezvani, MD, PhD, Scott R. Solomon, MD, Bipin N. Savani, MD, Raquel Nunes, MD, Agnes Yong, MD, PhD, John Schindler, PhD, Elizabeth J. Read, MD, Ellen S. Vitetta, PhD, A. John Barrett, MD
Journal: Blood
Blood (2006) 108 (11): 308.
https://doi.org/10.1182/blood.V108.11.308.308
Published: 2006
Journal Articles

Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation

Clinical Trials & Observations
Persis J. Amrolia, Giada Muccioli-Casadei, Helen Huls, Stuart Adams, April Durett, Adrian Gee, Eric Yvon, Heidi Weiss, Mark Cobbold, H. Bobby Gaspar, Cliona Rooney, Ingrid Kuehnle, Victor Ghetie, John Schindler, Robert Krance, Helen E. Heslop, Paul Veys, Ellen Vitetta, Malcolm K. Brenner
Journal: Blood
Blood (2006) 108 (6): 1797–1808.
https://doi.org/10.1182/blood-2006-02-001909
Published: 2006
Journal Articles

Reconstitution of Regulatory T Cells after Selective Depletion of CD25+ Host-Reactive Donor Lymphocytes from Allografts and Association with Acute Graft-Versus-Host-Disease.

Stephan Mielke, MD, Katayoun Rezvani, MD, PhD, Scott R. Solomon, MD, Yasemin Kilical, Bipin N. Savani, MD, Laura Wish, Charles S. Carter, John Schindler, PhD, Nancy Hensel, Roger Kurlander, MD, Elizabeth J. Read, MD, Ellen S. Vitetta, PhD, A. John Barrett, MD
Journal: Blood
Blood (2005) 106 (11): 595.
https://doi.org/10.1182/blood.V106.11.595.595
Published: 2005
Journal Articles

Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation

Clinical Trials & Observations
Scott R. Solomon, Stephan Mielke, Bipin N. Savani, Aldemar Montero, Laura Wisch, Richard Childs, Nancy Hensel, John Schindler, Victor Ghetie, Susan F. Leitman, Thao Mai, Charles S. Carter, Roger Kurlander, Elizabeth J. Read, Ellen S. Vitetta, A. John Barrett
Journal: Blood
Blood (2005) 106 (3): 1123–1129.
https://doi.org/10.1182/blood-2005-01-0393
Published: 2005
Journal Articles

Selective Depletion of Alloreacting CD25+ Cells from Stem Cell Allografts Can Reduce Acute Graft-Versus-Host Disease Following Matched Related Donor Transplantation.

Scott R. Solomon, M.D, Thao Tran, Charles S. Carter, M.D., Nancy Hensel, Laura Wisch, R.N., Stephan Mielke, M.D, Elizabeth Read, M.D, Victor Ghetie, M.D, John Schindler, M.D, Ellen Vitetta, M.D., John Barrett, M.D.
Journal: Blood
Blood (2004) 104 (11): 426.
https://doi.org/10.1182/blood.V104.11.426.426
Published: 2004
Journal Articles

A Phase-I Study of an Anti-CD25 Ricin A-Chain Immunotoxin (RFT5-SMPT-dgA) in Patients With Refractory Hodgkin's Lymphoma

Andreas Engert, Volker Diehl, Roland Schnell, Andrea Radszuhn, Maria-Theresia Hatwig, Silke Drillich, Gisela Schön, Heribert Bohlen, Hans Tesch, Martin-Leo Hansmann, Stefan Barth, John Schindler, Victor Ghetie, Jonathan Uhr, Ellen Vitetta
Journal: Blood
Blood (1997) 89 (2): 403–410.
https://doi.org/10.1182/blood.V89.2.403
Published: 1997