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Journal Articles

Genotypes of the Gene Encoding the Membrane Transporter SLC22A4 Are Associated with Molecular Relapse-Free Survival after Discontinuation of Imatinib Therapy in Patients with Chronic Myeloid Leukemia

Katerina Machova, Ali Albeer, Vaclava Polivkova, Katerina Vlcanova, Alice Fabarius, PhD, Hana Klamová, MD PhD, Birgit Spiess, Cornelius Waller, Tim H Brümmendorf, MD, Jolanta Dengler, MD, Volker Kunzmann, MD PhD, Andreas Burchert, MD, Petra Bělohlávková, MD PhD, Satu Mustjoki, MD PhD, Edgar Faber, MD, Jiri Mayer, MD, Daniela Žáčková, MD PhD, Panayiotis Panayiotidis, MD, Johan Richter, MD PhD, Henrik Hjorth-Hansen, MD, Susanne Saussele, MD, Markus Pfirrmann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1647.
https://doi.org/10.1182/blood-2019-129710
Published: 2019
Journal Articles

"Duration of Deep Molecular Response" Has Most Impact on the Success of Cessation of Tyrosine Kinase Inhibitor Treatment in Chronic Myeloid Leukemia - Results from the EURO-SKI Trial

Susanne Saussele, MD, Johan Richter, MD PhD, Joelle Guilhot, PhD, Henrik Hjorth-Hansen, MD, Antonio Medina de Almeida, MD PhD, Jeroen J. W. M. Janssen, MD, Jiri Mayer, Prof, MD SCs, Perttu Koskenvesa, MD, Panayiotis Panayiotidis, MD PhD, Ulla Olsson-Strömberg, MD PhD, Juan Luis Steegmann, MD PhD, Hanne Vestergaard, MD, Hans Ehrencrona, MD PhD, Veli Kairisto, Kateřina Machová Poláková, PhD, Martin Müller, MD, Satu Mustjoki, MDPhD, Marc G. Berger, MD PhD, Philippe Rousselot, Martine Escoffre-Barbe, MD, Gabriel Etienne, MD PhD, Jolanta Dengler, MD, Françoise Rigal-Huguet, MD, Nikolas von Bubnoff, MD, Hana Klamova, MD, Edgar Faber, MD, François Guilhot, MD, Kourosh Lotfi, MD, Delphine Rea, MD, Tim H. Brümmendorf, MD, Gorgine de Greef, MD, Leif Stenke, MD, Franck Emmanuel Nicolini, MD PhD, Laurence Legros, MD PhD, Andreas Burchert, MD, Jaroslava Voglová, MD, Aude Charbonnier, MD, Emmanuel Gyan, MDPhD, Maria-Elisabeth Goebeler, MD, Peter E. Westerweel, MD, Andreas Hochhaus, MD, Markus Pfirrmann, Francois-Xavier Mahon, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 313.
https://doi.org/10.1182/blood.V130.Suppl_1.313.313
Published: 2017
Journal Articles

Frequency of CTLA-4 Receptor Ligand (CD86, B7.2) -Positive Plasmacytoid Dendritic Cells Predicts Risk of Disease Recurrence after Tyrosine-Kinase Inhibitor Discontinuation in Chronic Myeloid Leukemia: Results from a Prospective Substudy of the Euroski Trial

Andreas Burchert, MD, Sabrina Inselmann, Susanne Saussele, Christian T. Dietz, PhD, Martin C. Müller, MD, Ekkehard Eigendorff, MD, Tim H. Brümmendorf, Prof MD, Cornelius Waller, MD, Jolanta Dengler, MD, Maria Elisabeth Goebeler, MD, Regina Herbst, MD, Gernot Freunek, MD, Stefan Hanzel, MD, Thomas Illmer, MD, Ying Wang, MD, Andreas Neubauer, MD, Thoralf Lange, MD, Andreas Hochhaus, MD, Finkernagel Florian, Cornelia A. Brendel, MD, Joelle Guilhot, PhD, Francois Xavier Mahon, MD PhD, Christin Schütz
Journal: Blood
Blood (2015) 126 (23): 599.
https://doi.org/10.1182/blood.V126.23.599.599
Published: 2015
Journal Articles

A Two-Fold Rise of BCR-ABL Transcript Levels Advises BCR-ABL Mutation Analysis in Imatinib-Treated Chronic Myeloid Leukemia (CML) - an Analysis of the Randomized CML-Study IV

Benjamin Hanfstein, MD, Niklas Westhoff, MD, Rüdiger Hehlmann, MD, Susanne Saussele, MD, Michael Lauseker, PhD, Thomas Ernst, MD, Philipp Erben, MD, Christian Dietz, PhD, Alice Fabarius, PhD, Ulrike Proetel, MD, Susanne Schnittger, PhD, Stefan W. Krause, MD, Joerg Schubert, MD, Hermann Einsele, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Gabriela M. Baerlocher, MD, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, Andreas Hochhaus, MD, Martin C. Müller, MD
Journal: Blood
Blood (2014) 124 (21): 3138.
https://doi.org/10.1182/blood.V124.21.3138.3138
Published: 2014
Journal Articles

Comparing the Prognostic Significance of Early Predictors of Survival in Chronic Myeloid Leukemia (CML) Treated with Imatinib - an Analysis of the Randomized CML-Study IV

Benjamin Hanfstein, MD, Michael Lauseker, PhD, Rüdiger Hehlmann, MD, Susanne Saussele, MD, Philipp Erben, MD, Christian Dietz, PhD, Alice Fabarius, PhD, Ulrike Proetel, MD, Lida Kalmanti, MD, Susanne Schnittger, PhD, Stefan W. Krause, MD, Jörg Schubert, MD, Hermann Einsele, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Gabriela M. Baerlocher, MD, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, Andreas Hochhaus, MD, Martin C. Müller, MD
Journal: Blood
Blood (2014) 124 (21): 156.
https://doi.org/10.1182/blood.V124.21.156.156
Published: 2014
Journal Articles

The Impact Of Balanced and Unbalanced Karyotypes On Prognosis Of CML: From Chronic Phase To Blast Crisis

Lida Kalmanti, MD, Christian Dietz, PhD, Claudia Haferlach, MD, Gudrun Göring, MD, Brigitte Schlegelberger, MD, Martine Jotterand, MD, Rüdiger Hehlmann, MD, Andreas Hochhaus, MD, Martin C. Müller, MD, Benjamin Hanfstein, MD, Ulrike Proetel, MD, Stefan W. Krause, MD, Hermann Einsele, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Michael Lauseker, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, MD, Susanne Saussele, MD, Alice Fabarius, PhD
Journal: Blood
Blood (2013) 122 (21): 3996.
https://doi.org/10.1182/blood.V122.21.3996.3996
Published: 2013
Journal Articles

Achievement Of a MR 5.0 Within the Randomized CML-Study IV: Feasibility, Differences Between Treatment Arms, and Prognostic Implications

Martin C. Müller, MD, Michael Lauseker, Rüdiger Hehlmann, MD, Benjamin Hanfstein, MD, Christian Dietz, PhD, Philipp Erben, MD, Alice Fabarius, PhD, Ulrike Proetel, MD, Susanne Schnittger, PhD, Stefan W. Krause, MD, Jörg Schubert, MD, Hermann Einsele, MD, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Karsten Spiekermann, PhD, Gabriela M. Baerlocher, MD, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, MD, Andreas Hochhaus, MD, Susanne Saussele, MD
Journal: Blood
Blood (2013) 122 (21): 4008.
https://doi.org/10.1182/blood.V122.21.4008.4008
Published: 2013
Journal Articles

Adverse Events (AE) Under Imatinib Treatment Over 10 Years: Results From 1501 Patients Of The Randomized CML-Study IV

Rüdiger Hehlmann, MD, Michael Lauseker, Annette Schreiber, MD, Ulrike Proetel, MD, Lida Kalmanti, MD, Andreas Hochhaus, MD, Martin C. Müller, MD, Alice Fabarius, PhD, Stefan W. Krause, MD, Hermann Einsele, MD, Jolanta Dengler, MD, Christiane Falge, MD, Gabriela M. Baerlocher, MD, Lothar Kanz, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, Prof MD, Cornelius F. Waller, MD, Karsten Spiekermann, PhD, Markus Pfirrmann, PhD, Susanne Saussele, MD, Joerg Hasford, MD
Journal: Blood
Blood (2013) 122 (21): 4012.
https://doi.org/10.1182/blood.V122.21.4012.4012
Published: 2013
Journal Articles

The Cytogenetic Profile In Lymphoid and Myeloid CML Blast Crisis

Lida Kalmanti, MD, Christian Dietz, PhD, Markus Pfirrmann, PhD, Claudia Haferlach, MD, Gudrun Göhring, MD, Brigitte Schlegelberger, MD, PhD, Martine Jotterand, MD, Rüdiger Hehlmann, MD, Andreas Hochhaus, MD, Martin C. Müller, MD, Benjamin Hanfstein, MD, Ulrike Proetel, MD, Stefan W. Krause, MD, Hermann Einsele, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, MD Prof, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Michael Lauseker, Joerg Hasford, MD, Wolf-Karsten Hofmann, MD, Susanne Saussele, MD, Alice Fabarius, PhD
Journal: Blood
Blood (2013) 122 (21): 1487.
https://doi.org/10.1182/blood.V122.21.1487.1487
Published: 2013
Journal Articles

Optimizing Early Prediction Of Outcome In CML Using The Exact Decline Of BCR-ABL Transcript Levels Within 3 Months Of Imatinib Treatment As a Prognostic Marker

Benjamin Hanfstein, MD, Valeria Shlyakhto, Michael Lauseker, Rüdiger Hehlmann, MD, Susanne Saussele, MD, Philipp Erben, MD, Christian Dietz, PhD, Alice Fabarius, PhD, Ulrike Proetel, MD, Susanne Schnittger, PhD, Stefan W. Krause, MD, Jörg Schubert, MD, Hermann Einsele, MD, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Gabriela M. Baerlocher, MD, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, MD, Andreas Hochhaus, MD, Martin C. Müller, MD
Journal: Blood
Blood (2013) 122 (21): 253.
https://doi.org/10.1182/blood.V122.21.253.253
Published: 2013
Journal Articles

Absolute BCR-ABL Transcript Levels At 3 Months but Not At Diagnosis Predict Survival of Chronic Myeloid Leukemia (CML) Patients On Imatinib Therapy

Benjamin Hanfstein, MD, Valeria Shlyakhto, Michael Lauseker, Philipp Erben, MD, Susanne Saussele, MD, Alice Fabarius, PhD, Ulrike Proetel, MD, Susanne Schnittger, PhD, Hans-Jochem Kolb, MD, Stefan W. Krause, Joerg Schubert, MD, Hermann Einsele, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, PhD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Karsten Spiekermann, PhD, Gabriela M. Baerlocher, MD, Markus Pfirrmann, Joerg Hasford, Wolf-Karsten Hofmann, Rüdiger Hehlmann, MD, Andreas Hochhaus, MD, Martin C. Müller, MD
Journal: Blood
Blood (2012) 120 (21): 3761.
https://doi.org/10.1182/blood.V120.21.3761.3761
Published: 2012
Journal Articles

Secondary Malignancies in CML Patients – Data From the German CML Study IV

Manuel Barreto Miranda, MD, Michael Lauseker, Ulrike Proetel, MD, Annette Schreiber, MD, Benjamin Hanfstein, MD, Gabriela M. Baerlocher, MD, Dominik Heim, MD, Gerhard Ehninger, Dieter K. Hossfeld, MD, Hans-Jochem Kolb, MD, Stefan W. Krause, MD, Christoph Nerl, MD, Hermann Einsele, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, PhD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Wolf-Karsten Hofmann, Martin C. Müller, MD, Markus Pfirrmann, Andreas Hochhaus, MD, Joerg Hasford, Rüdiger Hehlmann, MD, Susanne Saussele, MD
Journal: Blood
Blood (2012) 120 (21): 3746.
https://doi.org/10.1182/blood.V120.21.3746.3746
Published: 2012
Journal Articles

Impact of Balanced or Unbalanced Karyotype At Diagnosis On Prognosis of CML: Long-Term Observation From 1346 Patients of the Randomized CML Study IV

Alice Fabarius, PhD, Claudia Haferlach, MD, Andreas Hochhaus, MD, Martin C. Müller, MD, Benjamin Hanfstein, MD, Gudrun Göhring, MD, Brigitte Schlegelberger, Martine Jotterrand, MD, Ulrike Proetel, MD, Wolf-Karsten Hofmann, Stefan W. Krause, Hermann Einsele, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, PhD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Karsten Spiekermann, PhD, Michael Lauseker, Markus Pfirrmann, Joerg Hasford, Rüdiger Hehlmann, MD, Susanne Saussele, MD
Journal: Blood
Blood (2012) 120 (21): 913.
https://doi.org/10.1182/blood.V120.21.913.913
Published: 2012
Journal Articles

Substantially Improved Outcome of Adult Burkitt Non-Hodgkin Lymphoma and Leukemia Patients with Rituximab and a Short-Intensive Chemotherapy; Report of a Large Prospective Multicenter Trial

Dieter Hoelzer, MD, Jan Walewski, Hartmut Döhner, MD, Mathias Schmid, MD, Wolfgang Hiddemann, MD, PhD, Anja Baumann, MD, Hubert Serve, Prof. Dr. med., Ulrich Dührsen, Andreas Hüttmann, Eckhard Thiel, Jolanta Dengler, MD, Michael Kneba, MD, Markus Schuler, MD, Ingo Schmidt-Wolf, MD, Joachim Beck, MD, Bernd Hertenstein, Albrecht Reichle, Katarzyna Domanska-Czyz, Rainer Fietkau, MD, Heinz-August Horst, MD, Harald Rieder, MD, Stefan Schwartz, MD, Thomas Burmeister, MD, Nicola Goekbuget, MD
Journal: Blood
Blood (2012) 120 (21): 667.
https://doi.org/10.1182/blood.V120.21.667.667
Published: 2012
Journal Articles

Complete Molecular Remission (CMR 4.5) of CML Is Induced Faster by Dose – Optimized Imatinib and Predicts Better Survival - Results From the Randomized CML-Study IV

Rüdiger Hehlmann, MD, Michael Lauseker, Benjamin Hanfstein, MD, Martin C. Müller, MD, Annette Schreiber, MD, Ulrike Proetel, MD, Markus Pfirrmann, Claudia Haferlach, MD, Susanne Schnittger, PhD, Hermann Einsele, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, PhD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Gabriela M. Baerlocher, MD, Gerhard Ehninger, Dominik Heim, MD, Hermann Heimpel, Christoph Nerl, MD, Stefan W. Krause, Dieter K. Hossfeld, MD, Hans-Jochem Kolb, MD, Andreas Hochhaus, MD, Joerg Hasford, Susanne Saussele, MD
Journal: Blood
Blood (2012) 120 (21): 67.
https://doi.org/10.1182/blood.V120.21.67.67
Published: 2012
Journal Articles

Long Term Follow-up of 121 Elderly Patients with Philadelphia-Positive Acute Lymphoblastic Leukaemia (Ph+ALL) Treated in Prospective GMALL Trials Supports a Greater Emphasis On Allogeneic SCT as Definitive Postremission Therapy.

Heike Pfeifer, MD, Christoph Wettner, Barbara Wassmann, Aristoteles A.N. Giagounidis, Matthias Stelljes, MD, Ulrich Duehrsen, MD, Marc Schmalzing, MD, Markus Schaich, MD, Maike De Wit, Arnold Ganser, Winfried Gassmann, MD, PhD, Michael Pfreundschuh, MD, Nicolai Haertel, Knut Wendelin, MD, Mathias Schmid, MD, Hans Joachim Beck, Jolanta Dengler, MD, Heinz-August Horst, MD, Michael Lübbert, MD, Hubert Serve, Prof. Dr. med., Nicola Goekbuget, MD, Dieter Hoelzer, MD, Oliver G. Ottmann, MD
Journal: Blood
Blood (2012) 120 (21): 2608.
https://doi.org/10.1182/blood.V120.21.2608.2608
Published: 2012
Journal Articles

Distinct Characteristics of e13a2 versus e14a2 BCR-ABL Chronic Myeloid Leukemia under Upfront Treatment with Imatinib – an Analysis of the German CML Study IV,

Benjamin Hanfstein, MD, Philipp Erben, MD, Susanne Saussele, MD, Michael Lauseker, Ulrike Proetel, MD, Sven Haag, Susanne Schnittger, PhD, Claudia Haferlach, MD, Hans-Jochem Kolb, MD, Stefan W. Krause, MD, Christoph Nerl, MD, Dominik Heim, MD, Gabriela M. Baerlocher, MD, Jörg E. A. Schubert, MD, Hermann Einsele, MD, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Markus Pfirrmann, PhD, Jörg Hasford, MD, Wolf-Karsten Hofmann, MD, Rüdiger Hehlmann, MD, Andreas Hochhaus, MD, Martin C. Müller, MD, for The German CML Study Group, for The SAKK
Journal: Blood
Blood (2011) 118 (21): 3773.
https://doi.org/10.1182/blood.V118.21.3773.3773
Published: 2011
Journal Articles

Molecular and Cytogenetic Response After 3 Months of Imatinib Treatment Is Predictive for the Risk of Disease Progression and Death in Newly Diagnosed Chronic Myeloid Leukemia Patients – a Follow-up Analysis of the German CML Study IV

Benjamin Hanfstein, MD, Martin C. Müller, MD, Philipp Erben, MD, Michael Lauseker, Susanne Saussele, MD, Ulrike Proetel, MD, Susanne Schnittger, PhD, Claudia Haferlach, MD, Hans-Jochem Kolb, MD, Stefan W. Krause, MD, Christoph Nerl, MD, Dominik Heim, MD, Gabriela M. Baerlocher, MD, Jörg E. A. Schubert, MD, Hermann Einsele, MD, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Markus Pfirrmann, PhD, Jörg Hasford, MD, Wolf-Karsten Hofmann, MD, Rüdiger Hehlmann, MD, Andreas Hochhaus, MD, for The SAKK, for The German CML Study Group
Journal: Blood
Blood (2011) 118 (21): 783.
https://doi.org/10.1182/blood.V118.21.783.783
Published: 2011
Journal Articles

Updated Long-Term Results of a Randomized Comparison of Prophylactic and Pre-Emptive Imatinib Following Allogeneic Stem Cell Transplantation for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)

Heike Pfeifer, MD, B. Wassmann, MD, Wolfgang A. Bethge, MD, Jolanta Dengler, MD, Martin Bornhäuser, MD, Michael Stadler, MD, Dietrich Beelen, Andreas Günther, MD, Vladan Vucinic, Thomas Burmeister, MD, Matthias Stelljes, Rainer Schwerdtfeger, Kerstin Schaefer-Eckhart, Peter Bader, Hermann Kreyenberg, Peter Schuld, PhD, Hubert Serve, MD, Dieter Hoelzer, MD, Nicola Goekbuget, MD, Oliver G. Ottmann, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 247.
https://doi.org/10.1182/blood.V118.21.247.247
Published: 2011
Journal Articles

Time-Related Interpretation of Molecular Response Levels According to Long Term Overall and Progression-Free Survival of CML Patients on First-Line Imatinib Treatment

Martin C. Müller, MD, Benjamin Hanfstein, MD, Michael Lauseker, Philipp Erben, MD, Ulrike Proetel, MD, Susanne Schnittger, PhD, Hans-Jochem Kolb, MD, Stefan W. Krause, MD, Christoph Nerl, MD, Dominik Heim, MD, Gabriela M. Baerlocher, MD, Joerg E. A. Schubert, MD, Hermann Einsele, MD, Matthias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, MD, Cornelius F. Waller, MD, Markus Pfirrmann, PhD, Jörg Hasford, MD, Wolf-Karsten Hofmann, MD, Rüdiger Hehlmann, MD, Susanne Saussele, MD, Andreas Hochhaus, MD, for The SAKK, for The German CML Study Group
Journal: Blood
Blood (2011) 118 (21): 1681.
https://doi.org/10.1182/blood.V118.21.1681.1681
Published: 2011