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Journal Articles

Modulation of Thrombin-Induced Platelet Activation By Defibrotide

Kristin N. Maher, MD PhD, Xu Han, BS, MS, Keith B. Neeves, PhD, Marvin T. Nieman, PhD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 3614.

https://doi.org/10.1182/blood-2019-125945

Published: 2019

Journal Articles

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Marlie H Fisher, Greg Kirkpatrick, PhD, Courtney L Jones, PhD, Brett M. Stevens, PhD, Michael Callaghan, MD, Eric Pietras, PhD, Kenneth L. Jones, PhD, Christopher C. Porter, MD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 2316.

https://doi.org/10.1182/blood-2019-132032

Published: 2019

Journal Articles

Studying the Role of ETV6 in Megakaryopoiesis and Thrombopoiesis Using a Novel CRISPR-Cas9 Halotag Genome Editing Strategy

Marlie H Fisher, Leila J. Noetzli, PhD, Michael Callaghan, MD, Walter H. Kahr, MDPhDFRCPC, Jesse W Rowley, PhD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 2468.

https://doi.org/10.1182/blood-2019-131967

Published: 2019

Journal Articles

Rheumatoid Arthritis Causes Hematopoietic Stem Cell Reprogramming to Maintain Functionality

Blood (2018) 132 (Supplement 1): 2573.

https://doi.org/10.1182/blood-2018-99-120272

Published: 2018

Journal Articles

Single-Cell RNA-Seq Analysis of Native Murine Megakaryocytes from Young and Old Mice Reveals Significant Metabolic and Mitochondrial Differences throughout Megakaryocyte Development

Pavel Davizon-Castillo, MD, Kenneth L. Jones, PhD, George D Trahan, MS, Jorge Di Paola, MD

Blood (2018) 132 (Supplement 1): 1286.

https://doi.org/10.1182/blood-2018-99-120006

Published: 2018

Journal Articles

TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN)

Pavel Davizon-Castillo, MD, Brandon McMahon, MD, Sonia Aguila, PhD, Kenneth L. Jones, PhD, George D Trahan, MS, Katrina J. Ashworth, MS, David Bark, PhD, Robert A. Campbell, PhD, Kelly Higa, MS, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD

Blood (2018) 132 (Supplement 1): 1134.

https://doi.org/10.1182/blood-2018-99-119620

Published: 2018

Journal Articles

Prospective Diagnosis of VWD in a Large Cohort of Patients with Bleeding Symptoms through the Zimmerman Program

Veronica H Flood, MD, Pamela A Christopherson, Joan Cox Gill, MD, Kenneth Dale Friedman, MD, Sandra L Haberichter, PhD, Jorge Di Paola, MD, Paula D. James, MD, Janna M. Journeycake, MD, Steven R. Lentz, MD PhD, Cindy A. Leissinger, MD, Margaret V. Ragni, MD MPH, Madhvi Rajpurkar, MD, Jonathan C. Roberts, MD, Amy Shapiro, Robert F. Sidonio, Robert R Montgomery, MD, Thomas C. Abshire, MD

Blood (2018) 132 (Supplement 1): 979.

https://doi.org/10.1182/blood-2018-99-110650

Published: 2018

Journal Articles

Single Cell RNA Sequencing of Blood Outgrowth Endothelial Cells from Patients with Low Von Willebrand Factor Reveal Multiple Novel Signaling Pathways

Christopher J. Ng, MD, Alice Liu, BS, Katrina J. Ashworth, MS, Kenneth L. Jones, PhD, Jorge Di Paola, MD

Blood (2018) 132 (Supplement 1): 982.

https://doi.org/10.1182/blood-2018-99-116694

Published: 2018

Journal Articles

Epigenetic Profiles of Primary Endothelial Cells from Patients with Low VWF Levels

Christopher J. Ng, MD, Alice Liu, BS, Katrina J. Ashworth, MS, Kenneth L. Jones, PhD, Jorge Di Paola, MD

Blood (2018) 132 (Supplement 1): 983.

https://doi.org/10.1182/blood-2018-99-116719

Published: 2018

Journal Articles

Genotypic and Phenotypic Analysis of Adolescents with Heavy Menstrual Bleeding and Low Von Willebrand Activity - Interim Report of a Multi-Center Study

Lakshmi Srivaths, MD, Jorge Di Paola, MD, Charles Minard, PhD, Sarah H. O'Brien, MD MSc, Allison Wheeler, MD, Shilpa Jain, MDMPH, Mukta Sharma, MD MPH, Roshni Kulkarni, Eric S. Mullins, MD, Margaret V. Ragni, MD MPH, Jennifer Dietrich, Peter A. Kouides, MD

Blood (2018) 132 (Supplement 1): 984.

https://doi.org/10.1182/blood-2018-99-113064

Published: 2018

Journal Articles

Endothelial Colony Forming Cells from Individuals with Low VWF Levels Demonstrate Impairment in Stimulated VWF Release

Christopher J. Ng, MD, Katrina J. Ashworth, MS, Marilyn J Manco-Johnson, MD, Christopher Baker, MD, Jorge Di Paola, MD

Blood (2017) 130 (Supplement 1): 21.

https://doi.org/10.1182/blood.V130.Suppl_1.21.21

Published: 2017

Journal Articles

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Leila Noetzli, BS, Jesse W Rowley, PhD, Pavel Davizon-Castillo, MD, Greg Kirkpatrick, Katrina J. Ashworth, MS, Sonia Aguila, PhD, Christopher C. Porter, MD, Eric Martin Pietras, PhD, Andrew S. Weyrich, PhD, Jorge Di Paola, MD

Blood (2017) 130 (Supplement 1): 1035.

https://doi.org/10.1182/blood.V130.Suppl_1.1035.1035

Published: 2017

Journal Articles

Alterations in Cytokine Profiles Have Potential Uses As Biomarkers for Pediatric Venous Thromboembolism

Robert L Meller, III, BS, Christine Brzezinski, MS, Christopher J. Ng, MD, Allaura Cox, BS, Julie Smith, BS, Jorge Di Paola, MD, Marilyn J Manco-Johnson, MD, Brian R. Branchford, MD

Blood (2017) 130 (Supplement 1): 1078.

https://doi.org/10.1182/blood.V130.Suppl_1.1078.1078

Published: 2017

Journal Articles

Altered HSC Programming Drives Aberrant Blood Output Underlying RA Pathogenesis

Taylor Mills, BA, Giovany Hernandez, Susan Kuldanek, MD, Jennifer L Rabe, BS, BA, Greg Kirkpatrick, Leila Noetzli, BS, Erin Severs, Diana Ir, Sumitra Acharya, Biniam Adane, Craig T. Jordan, PhD, Jorge Di Paola, MD, Daniel Frank, Kristine Kuhn, Michael Holers, MD, Nirmal Banda, Eric Martin Pietras, PhD

Blood (2017) 130 (Supplement 1): 3748.

https://doi.org/10.1182/blood.V130.Suppl_1.3748.3748

Published: 2017

Journal Articles

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Pavel Davizon-Castillo, MD, Ken L. Jones, PhD, Sonia Aguila, PhD, David Bark, PhD, Katrina J. Ashworth, MS, Kelly Higa, MS, Eric Martin Pietras, PhD, Robert A. Campbell, PhD, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD

Blood (2017) 130 (Supplement 1): 292.

https://doi.org/10.1182/blood.V130.Suppl_1.292.292

Published: 2017

Journal Articles

Clinical Outcomes of Catheter-Associated Venous Thrombosis in the Post-Hematopoietic Stem Cell Transplant Setting

Genevieve Moyer, MD, Jonathan A Gutman, MD, Jorge Di Paola, MD, Tyler W. Buckner, MD MSc

Blood (2017) 130 (Supplement 1): 4901.

https://doi.org/10.1182/blood.V130.Suppl_1.4901.4901

Published: 2017

Journal Articles

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

Michelle Lavin, MB FRCPath, Sonia Aguila, PhD, Sonja Schneppenheim, MD, Niall Dalton, BSc, Jamie M O'Sullivan, PhD, Niamh M O'Connell, MB, FRCPath, PhD, Kevin M. Ryan, MB, Mary Byrne, MSc, Margaret Nolan, BSc, Roger Preston, PhD, Ulrich Budde, MD, Paula D. James, MD, Jorge Di Paola, MD, James S O'Donnell, MD PhD

Blood (2016) 128 (22): 873.

https://doi.org/10.1182/blood.V128.22.873.873

Published: 2016

Journal Articles

ETV6 Regulates Pax5 Expression in Early B Cell Development

Courtney L. Jones, PhD, Gregory Kirkpatrick, Courtney Fleenor, Welsh Seth, Leila J Noetzli, BS, Susan Fosmire, Dmitry Baturin, Xiayuan Liang, MD, Giovanny Hernandez, Eric Martin Pietras, PhD, Craig T Jordan, PhD, Jesse W Rowley, PhD, Jorge Di Paola, MD, James R. Hagman, Christopher C. Porter, MD

Blood (2016) 128 (22): 2655.

https://doi.org/10.1182/blood.V128.22.2655.2655

Published: 2016

Journal Articles

Novel Congenital Platelet Disorders

Jorge Di Paola, MD

Blood (2016) 128 (22): SCI-39.

https://doi.org/10.1182/blood.V128.22.SCI-39.SCI-39

Published: 2016

Journal Articles

Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging

Pavel Davizon-Castillo, Katrina Ashworth, MS, Kelly Higa, MS, Giovanny Hernandez, Sumitra Acharya, Robert A. Campbell, PhD, Matthew Rondina, MD, Colm B. Collins, PhD, Anthony Donato, MD, Lisa Lesniewski, James DeGregori, Michael Holer, Nirmal Banda, Jorge Di Paola, MD, Eric Martin Pietras, PhD

Blood (2016) 128 (22): 3747.

https://doi.org/10.1182/blood.V128.22.3747.3747

Published: 2016

NARROW

Modulation of Thrombin-Induced Platelet Activation By Defibrotide

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Studying the Role of ETV6 in Megakaryopoiesis and Thrombopoiesis Using a Novel CRISPR-Cas9 Halotag Genome Editing Strategy

Rheumatoid Arthritis Causes Hematopoietic Stem Cell Reprogramming to Maintain Functionality

Single-Cell RNA-Seq Analysis of Native Murine Megakaryocytes from Young and Old Mice Reveals Significant Metabolic and Mitochondrial Differences throughout Megakaryocyte Development

TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN)

Prospective Diagnosis of VWD in a Large Cohort of Patients with Bleeding Symptoms through the Zimmerman Program

Single Cell RNA Sequencing of Blood Outgrowth Endothelial Cells from Patients with Low Von Willebrand Factor Reveal Multiple Novel Signaling Pathways

Epigenetic Profiles of Primary Endothelial Cells from Patients with Low VWF Levels

Genotypic and Phenotypic Analysis of Adolescents with Heavy Menstrual Bleeding and Low Von Willebrand Activity - Interim Report of a Multi-Center Study

Endothelial Colony Forming Cells from Individuals with Low VWF Levels Demonstrate Impairment in Stimulated VWF Release

A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects

Alterations in Cytokine Profiles Have Potential Uses As Biomarkers for Pediatric Venous Thromboembolism

Altered HSC Programming Drives Aberrant Blood Output Underlying RA Pathogenesis

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Clinical Outcomes of Catheter-Associated Venous Thrombosis in the Post-Hematopoietic Stem Cell Transplant Setting

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

ETV6 Regulates Pax5 Expression in Early B Cell Development

Novel Congenital Platelet Disorders

Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging

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American Society of Hematology

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ASH Publications

American Society of Hematology

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