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Journal Articles

PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications

Kathleen Freson, Karen Peeters, Rita De Vos, Christine Wittevrongel, Chantal Thys, Marc F. Hoylaerts, Jos Vermylen, Chris Van Geet

Blood (2008) 111 (4): 1885–1893.

https://doi.org/10.1182/blood-2007-06-098558

Published: 2008

Includes: Supplemental data

Journal Articles

Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13

Arnaud Bonnefoy, Kim Daenens, Hendrik B. Feys, Rita De Vos, Petra Vandervoort, Jos Vermylen, Jack Lawler, Marc F. Hoylaerts

Blood (2006) 107 (3): 955–964.

https://doi.org/10.1182/blood-2004-12-4856

Published: 2006

Journal Articles

The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure

Kathleen Freson, Rita De Vos, Christine Wittevrongel, Chantal Thys, Johan Defoor, Luc Vanhees, Jos Vermylen, Kathelijne Peerlinck, Chris Van Geet

Blood (2005) 106 (7): 2356–2362.

https://doi.org/10.1182/blood-2005-02-0723

Published: 2005

Includes: Supplemental data

Journal Articles

Rupture of T Cell Tolerance to Self Factor VIII in Mild/Moderate Hemophilia A.

Marc G. Jacquemin, MD, PhD, Renaud Lavend’homme, Ms, Benhida Abdellah, Kathelijne Peerlinck, MD, PhD, Jos Vermylen, MD, PhD, Véronique Deneys, MD, PhD, Jean-Marie Saint-Remy, MD, PhD, Cédric Hermans, MD, PhD

Blood (2004) 104 (11): 3076.

https://doi.org/10.1182/blood.V104.11.3076.3076

Published: 2004

Journal Articles

VPAC1 Receptor-Mediated Regulation of Megakaryopoiesis.

Kathleen Freson, PhD, Chantal Thys, Christine Wittevrongel, Rita De Vos, PhD, Jos Vermylen, PhD, MD, Marc F. Hoylaerts, PhD, MD, Chris Van Geet, PhD, MD

Blood (2004) 104 (11): 735.

https://doi.org/10.1182/blood.V104.11.735.735

Published: 2004

Journal Articles

Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development

Roseline d'Oiron, Jean-Maurice Lavergne, Renaud Lavend'homme, Abdellah Benhida, Jean-Claude Bordet, Claude Negrier, Kathelijne Peerlinck, Jos Vermylen, Jean-Marie Saint-Remy, Marc Jacquemin

Blood (2004) 103 (1): 155–157.

https://doi.org/10.1182/blood-2003-04-1321

Published: 2004

Journal Articles

Overexpression of the platelet P2X 1 ion channel in transgenic mice generates a novel prothrombotic phenotype

Cécile Oury, Marijke J. E. Kuijpers, Emese Toth-Zsamboki, Arnaud Bonnefoy, Sophie Danloy, Ingrid Vreys, Marion A. H. Feijge, Rita De Vos, Jos Vermylen, Johan W. M. Heemskerk, Marc F. Hoylaerts

Blood (2003) 101 (10): 3969–3976.

https://doi.org/10.1182/blood-2002-10-3215

Published: 2003

Journal Articles

CD4 + T-cell clones specific for wild-type factor VIII: a molecular mechanism responsible for a higher incidence of inhibitor formation in mild/moderate hemophilia A

Marc Jacquemin, Valérie Vantomme, Cécile Buhot, Renaud Lavend'homme, Wivine Burny, Nathalie Demotte, Pascal Chaux, Kathelijne Peerlinck, Jos Vermylen, Bernard Maillere, Pierre van der Bruggen, Jean-Marie Saint-Remy

Blood (2003) 101 (4): 1351–1358.

https://doi.org/10.1182/blood-2002-05-1369

Published: 2003

Journal Articles

Shielding the front-strand β3 of the von Willebrand factor A1 domain inhibits its binding to platelet glycoprotein Ibα

Arnaud Bonnefoy, Hiroshi Yamamoto, Chantal Thys, Morikazu Kito, Jos Vermylen, Marc F. Hoylaerts

Blood (2003) 101 (4): 1375–1383.

https://doi.org/10.1182/blood-2002-06-1818

Published: 2003

Journal Articles

Thrombogenicity of β 2 -glycoprotein I–dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster

Milosz Jankowski, Ingrid Vreys, Christine Wittevrongel, Doris Boon, Jos Vermylen, Marc. F. Hoylaerts, Jef Arnout

Blood (2003) 101 (1): 157–162.

https://doi.org/10.1182/blood-2002-05-1310

Published: 2003

Journal Articles

P2X 1 -mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen

Cécile Oury, Emese Toth-Zsamboki, Jos Vermylen, Marc F. Hoylaerts

Blood (2002) 100 (7): 2499–2505.

https://doi.org/10.1182/blood-2002-03-0812

Published: 2002

Journal Articles

Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia

Gregor Theilmeier, Carine Michiels, Erik Spaepen, Ingrid Vreys, Désiré Collen, Jos Vermylen, Marc F. Hoylaerts

Blood (2002) 99 (12): 4486–4493.

https://doi.org/10.1182/blood.V99.12.4486

Published: 2002

Journal Articles

Does the P 2X1del variant lacking 17 amino acids in its extracellular domain represent a relevant functional ion channel in platelets?

Cécile Oury, Emese Toth-Zsamboki, Jos Vermylen, Marc F. Hoylaerts

Blood (2002) 99 (6): 2275–2277.

https://doi.org/10.1182/blood-2001-11-0065

Published: 2002

Journal Articles

Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation

Kathleen Freson, Koen Devriendt, Gert Matthijs, Achiel Van Hoof, Rita De Vos, Chantal Thys, Kristien Minner, Marc F. Hoylaerts, Jos Vermylen, Chris Van Geet

Blood (2001) 98 (1): 85–92.

https://doi.org/10.1182/blood.V98.1.85

Published: 2001

Journal Articles

A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor

Marc Jacquemin, Renaud Lavend'homme, Abdellah Benhida, Beatrijs Vanzieleghem, Roseline d'Oiron, Jean-Maurice Lavergne, Hans H. Brackmann, Rainer Schwaab, Thierry VandenDriessche, Marinee K. L. Chuah, Marc Hoylaerts, Jean Guy G. Gilles, Kathelijne Peerlinck, Jos Vermylen, Jean-Marie R. Saint-Remy

Blood (2000) 96 (3): 958–965.

https://doi.org/10.1182/blood.V96.3.958

Published: 2000

Journal Articles

Vascular release of plasminogen activator inhibitor-1 impairs fibrinolysis during acute arterial thrombosis in mice

Tomihisa Kawasaki, Mieke Dewerchin, Henri R. Lijnen, Jos Vermylen, Marc F. Hoylaerts

Blood (2000) 96 (1): 153–160.

https://doi.org/10.1182/blood.V96.1.153

Published: 2000

Journal Articles

A human antibody directed to the factor VIII C1 domain inhibits factor VIII cofactor activity and binding to von Willebrand factor

Marc Jacquemin, Abdellah Benhida, Kathelijne Peerlinck, Benoı̂t Desqueper, Luc Vander Elst, Renaud Lavend'homme, Roseline d'Oiron, Rainer Schwaab, Marleen Bakkus, Kris Thielemans, Jean-Guy Gilles, Jos Vermylen, Jean-Marie Saint-Remy

Blood (2000) 95 (1): 156–163.

https://doi.org/10.1182/blood.V95.1.156

Published: 2000

Journal Articles

Circulating Activated Platelets Assist THP-1 Monocytoid/Endothelial Cell Interaction Under Shear Stress

Gregor Theilmeier, Tim Lenaerts, Claude Remacle, Désiré Collen, Jos Vermylen, Marc F. Hoylaerts

Blood (1999) 94 (8): 2725–2734.

https://doi.org/10.1182/blood.V94.8.2725.420k18_2725_2734

Published: 1999

Journal Articles

Antifactor VIII Antibody Inhibiting Allogeneic but not Autologous Factor VIII in Patients With Mild Hemophilia A

Kathelijne Peerlinck, Marc G. Jacquemin, Jef Arnout, Marc F. Hoylaerts, Jean Guy G. Gilles, Renaud Lavend’homme, Karen M. Johnson, Kathleen Freson, Dorothea Scandella, Jean-Marie R. Saint-Remy, Jos Vermylen

Blood (1999) 93 (7): 2267–2273.

https://doi.org/10.1182/blood.V93.7.2267

Published: 1999

Journal Articles

Mechanism and Kinetics of Factor VIII Inactivation: Study With an IgG4 Monoclonal Antibody Derived From a Hemophilia A Patient With Inhibitor

Marc G. Jacquemin, Benoı̂t G. Desqueper, Abdellah Benhida, Luc Vander Elst, Marc F. Hoylaerts, Marleen Bakkus, Kris Thielemans, Jef Arnout, Kathelijne Peerlinck, Jean Guy G. Gilles, Jos Vermylen, Jean-Marie R. Saint-Remy

Blood (1998) 92 (2): 496–506.

https://doi.org/10.1182/blood.V92.2.496

Published: 1998

NARROW

PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications

Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13

The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure

Rupture of T Cell Tolerance to Self Factor VIII in Mild/Moderate Hemophilia A.

VPAC1 Receptor-Mediated Regulation of Megakaryopoiesis.

Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development

Overexpression of the platelet P2X 1 ion channel in transgenic mice generates a novel prothrombotic phenotype

CD4 + T-cell clones specific for wild-type factor VIII: a molecular mechanism responsible for a higher incidence of inhibitor formation in mild/moderate hemophilia A

Shielding the front-strand β3 of the von Willebrand factor A1 domain inhibits its binding to platelet glycoprotein Ibα

Thrombogenicity of β 2 -glycoprotein I–dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster

P2X 1 -mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen

Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia

Does the P 2X1del variant lacking 17 amino acids in its extracellular domain represent a relevant functional ion channel in platelets?

Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation

A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor

Vascular release of plasminogen activator inhibitor-1 impairs fibrinolysis during acute arterial thrombosis in mice

A human antibody directed to the factor VIII C1 domain inhibits factor VIII cofactor activity and binding to von Willebrand factor

Circulating Activated Platelets Assist THP-1 Monocytoid/Endothelial Cell Interaction Under Shear Stress

Antifactor VIII Antibody Inhibiting Allogeneic but not Autologous Factor VIII in Patients With Mild Hemophilia A

Mechanism and Kinetics of Factor VIII Inactivation: Study With an IgG4 Monoclonal Antibody Derived From a Hemophilia A Patient With Inhibitor

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American Society of Hematology

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American Society of Hematology

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