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Joshua Schwieterman
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Journal Articles

Selective degradation of oncogenic signaling nodes by momelotinib-based protacs exerts potent anti-leukemic response in B-ALL, AML, and MF while sparing normal cells

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Joshua Schwieterman, Sekhu Ansari, Mohammad Azam
Journal: Blood
Blood (2025) 146 (Supplement 1): 6108.
https://doi.org/10.1182/blood-2025-6108
Published: 2025
Journal Articles

Enhanced antileukemic activity of momelotinib in combination with venetoclax and azacitidine compared to gilteritinib-based combination

Free
Zachary Kincaid, Sekhu Ansari, Joshua Schwieterman, Mary Antonysamy, Dwaipayan Patnaik, Shane O'Brien, Michael McCabe, Mohammad Azam
Journal: Blood
Blood (2025) 146 (Supplement 1): 7850.
https://doi.org/10.1182/blood-2025-7850
Published: 2025
Journal Articles

Negative feedback regulation of nfkb, MAPK, and JAK-STAT drives adaptive resistance to gilteritinib in AML

Free
Meenu Kesarwani, Mohammad Azhar, Zachary Kincaid, Sekhu Ansari, Joshua Schwieterman, Mohammad Azam
Journal: Blood
Blood (2025) 146 (Supplement 1): 1514.
https://doi.org/10.1182/blood-2025-1514
Published: 2025
Journal Articles

Novel BCR::ABL1 fusion alongside T315I reveals mechanism for dual ponatinib/asciminib resistance and proves sensitive to addition of axitinib

Free
Valentina Nardi, Mohammad Azam, Joshua Schwieterman, Sekhu Ansari, Meenu Kesarwani, George Daley, Zachary Kincaid
Journal: Blood
Blood (2025) 146 (Supplement 1): 1501.
https://doi.org/10.1182/blood-2025-1501
Published: 2025
Journal Articles

Momelotinib-mediated transcriptional reprogramming induces synthetic lethal interaction with calcineurin-NFAT signaling

Free
Sekhu Ansari, Meenu Kesarwani, Zachary Kincaid, Mohammad Azhar, Joshua Schwieterman, Mohammad Azam
Journal: Blood
Blood (2025) 146 (Supplement 1): 756.
https://doi.org/10.1182/blood-2025-756
Published: 2025
Journal Articles

A Novel BCR::ABL1 Rearrangement Harboring the Gatekeeper Mutation Drives Hyper-Kinase Activity Conferring Resistance to Ponatinib and Asciminib Combination Therapy

Free
Valentina Nardi, Joshua Schwieterman, Zachary Kincaid, Andrew M. Brunner, Maria Reyes, Gabriel K. Griffin, Sekhu Ansari, Mohammad Azam
Journal: Blood
Blood (2024) 144 (Supplement 1): 4541.
https://doi.org/10.1182/blood-2024-211279
Published: 2024