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Journal Articles

Platelet-Targeted Gene Therapy Induces Robust Immune Tolerance Even in a Primed Model Via Peripheral Clonal Deletion of CD4 and CD8 T Cells and Expansion of Treg Cells

Jing Li, MD PhD, Juan Chen, PhD, Jocelyn A. Schroeder, Qizhen Shi, MDPhD

Blood (2020) 136 (Supplement 1): 2.

https://doi.org/10.1182/blood-2020-140851

Published: 2020

Journal Articles

Updated Phase 1 Results of a First-in-Human Open-Label Study of Lcar-B38M, a Structurally Differentiated Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting B-Cell Maturation Antigen (Bcma)

Blood (2019) 134 (Supplement_1): 1858.

https://doi.org/10.1182/blood-2019-130008

Published: 2019

Journal Articles

Differential Expression of CD49f Discriminates the Independently Emerged Hematopoietic Stem Cells and Erythroid-Biased Progenitors

Ai-Ning Xu, Dan Liu, Yu-Ting Dai, Fan Zhang, Jian Shen, MSc, Cheng-Long Hu, Chun-Hui Xu, Yuan-Liang Zhang, Yin-Yin Xie, Qiu-Hua Huang, Peng-Fei Xu, Lan Wang, Lin Cheng, Jinyan Huang, PhD, Zhu Chen, PhD, Sai-Juan Chen, PhD, Xiao-Jian Sun, PhD

Blood (2019) 134 (Supplement_1): 3700.

https://doi.org/10.1182/blood-2019-130429

Published: 2019

Journal Articles

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

Weiqing Jing, MD PhD, Juan Chen, PhD, Yuanhua Cai, MD, Yingyu Chen, PhD, Jocelyn A. Schroeder, Weiguo Cui, MD PhD, Qizhen Shi, MD PhD

Blood (2019) 134 (Supplement_1): 92.

https://doi.org/10.1182/blood-2019-123777

Published: 2019

Journal Articles

Dynamic Analysis of Cytokine Profile for Cytokine Release Syndrome in Multiple Myeloma Patients after CAR-T Cell Therapy

Shuangshuang Yang, MD, Lijuan Chen, MD PhD, Jie Xu, MD PhD, Frank Xiao-Hu Fan, MD PhD, Sun Yan, PhD, Wen Wu, MD PhD, Yan Wang, MD, Jin Wang, MD PhD, Shiwei Jin, MD, Yuebo Zhou, Yuanfang Liu, MD PhD, Yan Zhuang, PhD, Wu Zhang, PhD, Jun-Min Li, Jian Hou, PhD MD, Jian-Yong Li, MD PhD, Zhu Chen, PhD, Jian-Qing Mi, MD PhD, Sai-Juan Chen, PhD

Blood (2019) 134 (Supplement_1): 5617.

https://doi.org/10.1182/blood-2019-131799

Published: 2019

Journal Articles

Setd2 Is Critical for Maintaining Hematopoietic Homeostasis

Yuanliang Zhang, Jiewen Sun, Zhu Chen, PhD, Sai-Juan Chen, PhD, Xiaojian Sun, Qiuhua Huang

Blood (2017) 130 (Supplement 1): 2414.

https://doi.org/10.1182/blood.V130.Suppl_1.2414.2414

Published: 2017

Journal Articles

Effective Treatment of Relapsed/Refractory Multiple Myeloma Including Extramedullary Involvement By BCMA-Specific Chimeric Antigen Receptor-Modified T Cells

Jian-Qing Mi, MD PhD, Xiaohu (Frank) Fan, PhD, Jie Xu, PhDMD, Yuanfang Liu, MD PhD, Yan Zhuang, PhD, Shuangshuang Yang, Wu Zhang, PhD, Bing Chen, MD PhD, Yueying Wang, PhD, Xiangqin Weng, Junmin Li, Weijun Fu, MD, Hua Jiang, MD, Li Zhu, Zhu Chen, PhD, Sai-Juan Chen, PhD, Jian Hou, PhD MD

Blood (2017) 130 (Supplement 1): 3115.

https://doi.org/10.1182/blood.V130.Suppl_1.3115.3115

Published: 2017

Journal Articles

Platelet-Targeted Gene Therapy of Hemophilia a Using Hematopoietic Stem Cells Derived from Genome-Edited Induced Pluripotent Stem Cells

Dawei Wang, Guowei Zhang, Junjie Gu, Xiaohu Shao, Xiaohong Pan, Shuxian Yao, Ying Jin, Qizhen Shi, MD PhD, Zhu Chen, PhD, Sai-Juan Chen, PhD

Blood (2017) 130 (Supplement 1): 2063.

https://doi.org/10.1182/blood.V130.Suppl_1.2063.2063

Published: 2017

Journal Articles

Platelet-Targeted Gene Transfer Induces Immune Tolerance in a Primed Model

Jing Li, MD PhD, Juan Chen, PhD, Jocelyn Schroeder, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2017) 130 (Supplement 1): 4612.

https://doi.org/10.1182/blood.V130.Suppl_1.4612.4612

Published: 2017

Journal Articles

In Vivo CRISPR/Cas9-Targeted Genome Editing Recovers Factor IX Expression Restoring Haemostasis in a Mouse Model

Qiang Wang, MD, Lin Zhang, PhD, Zhu Chen, PhD, Sai-Juan Chen, PhD

Blood (2017) 130 (Supplement 1): 5562.

https://doi.org/10.1182/blood.V130.Suppl_1.5562.5562

Published: 2017

Journal Articles

Platelet-Targeted Gene Transfer Prevents Graft Rejection and Induces Immune Tolerance Even in a Primed Model

Xiaofeng Luo, MD, PhD, Jing Li, MD PhD, Juan Chen, PhD, Jocelyn A. Schroeder, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 2315.

https://doi.org/10.1182/blood.V128.22.2315.2315

Published: 2016

Journal Articles

The Impact of VWF on FVIII Immune Responses in Hemophilia a Mice with Pre-Existing Anti-FVIII Immunity

Juan Chen, PhD, Jocelyn A. Schroeder, Xiaofeng Luo, MD PhD, Robert R. Montgomery, MD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 84.

https://doi.org/10.1182/blood.V128.22.84.84

Published: 2016

Journal Articles

Cannabinoid Receptor Signaling As a Target for Personalized Therapy in Aggressive B Cell Lymphomas

Lan Pham, PhD, Juan Chen, PhD, Archie Tamayo, MS, Jerry Bryant, David Yang, PhD, Richard J. Ford, Jr., MD PhD

Blood (2016) 128 (22): 4181.

https://doi.org/10.1182/blood.V128.22.4181.4181

Published: 2016

Journal Articles

Preclinical Evaluation of the Oral Proteasome Inhibitor Ixazomib in Diffuse Large B-Cell Lymphoma

Wei Liu, MD, Archie Tamayo, MS, Juan Chen, PhD, Shimin Hu, PhD MD, Richard J. Ford, Jr., MD PhD, Lan Pham, PhD

Blood (2015) 126 (23): 4003.

https://doi.org/10.1182/blood.V126.23.4003.4003

Published: 2015

Journal Articles

Platelet-Targeted Gene Transfer Induces Immune Tolerance through Two Distinct Pathways

Xiaofeng Luo, MD, Juan Chen, PhD, Jocelyn Schroeder, Christina K Baumgartner, PhD, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2015) 126 (23): 4423.

https://doi.org/10.1182/blood.V126.23.4423.4423

Published: 2015

Journal Articles

Immune Tolerance Developed in Platelet-Targeted FVIII Gene Therapy in Hemophilia Mice Is CD4 + T Cell-Mediated

Yingyu Chen, PhD, Xiaofeng Luo, MD, Juan Chen, PhD, Jocelyn Schroeder, Christina K Baumgartner, PhD, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2015) 126 (23): 1071.

https://doi.org/10.1182/blood.V126.23.1071.1071

Published: 2015

Journal Articles

The Impact of GPIba on the Efficacy of Platelet-Targeted FVIII Gene Therapy in Hemophilia a with Pre-Existing Anti-FVIII Immunity

Juan Chen, PhD, Jocelyn Schroeder, Xiaofeng Luo, MD, Robert R Montgomery, MD, Qizhen Shi, MD PhD

Blood (2015) 126 (23): 1067.

https://doi.org/10.1182/blood.V126.23.1067.1067

Published: 2015

Journal Articles

High IDH1 Expression Is Associated with a Poor Prognosis in Cytogenetically Normal Acute Myeloid Leukemia

Qiu-Ling Ma, Jing-Han Wang, Yun-gui Wang, Chao Hu, Qi-Tian Mu, Meng-Xia Yu, Lei Wang, Dong-Mei Wang, Min Yang, Xiu-Feng Yin, Fei-Fei Chen, Sha-Sha Lu, Jian Chen, Zhi-Juan Zhu, Sai-Juan Chen, PhD, MD, Jie Jin, MD

Blood (2014) 124 (21): 5314.

https://doi.org/10.1182/blood.V124.21.5314.5314

Published: 2014

Journal Articles

Prognostic Significance of Minimal Residual Disease in Adult Patients with B-Lineage Acute Lymphoblastic Leukemia by 8-Color Flow Cytometry

Xiang-Qin Weng, Yang Shen, MD, Yan Sheng, Bing Chen, PhD, Jing-han Wang, PhD, Jun-ming Li, MD, Yong-Mei Zhu, Sai-Juan Chen, PhD

Blood (2012) 120 (21): 4789.

https://doi.org/10.1182/blood.V120.21.4789.4789

Published: 2012

Journal Articles

Serum 2-Hydroxyglutarate Level Is a Prognostic Marker in Acute Myeloid Leukemia

Blood (2012) 120 (21): 1433.

https://doi.org/10.1182/blood.V120.21.1433.1433

Published: 2012

NARROW

Platelet-Targeted Gene Therapy Induces Robust Immune Tolerance Even in a Primed Model Via Peripheral Clonal Deletion of CD4 and CD8 T Cells and Expansion of Treg Cells

Updated Phase 1 Results of a First-in-Human Open-Label Study of Lcar-B38M, a Structurally Differentiated Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting B-Cell Maturation Antigen (Bcma)

Differential Expression of CD49f Discriminates the Independently Emerged Hematopoietic Stem Cells and Erythroid-Biased Progenitors

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

Dynamic Analysis of Cytokine Profile for Cytokine Release Syndrome in Multiple Myeloma Patients after CAR-T Cell Therapy

Setd2 Is Critical for Maintaining Hematopoietic Homeostasis

Effective Treatment of Relapsed/Refractory Multiple Myeloma Including Extramedullary Involvement By BCMA-Specific Chimeric Antigen Receptor-Modified T Cells

Platelet-Targeted Gene Therapy of Hemophilia a Using Hematopoietic Stem Cells Derived from Genome-Edited Induced Pluripotent Stem Cells

Platelet-Targeted Gene Transfer Induces Immune Tolerance in a Primed Model

In Vivo CRISPR/Cas9-Targeted Genome Editing Recovers Factor IX Expression Restoring Haemostasis in a Mouse Model

Platelet-Targeted Gene Transfer Prevents Graft Rejection and Induces Immune Tolerance Even in a Primed Model

The Impact of VWF on FVIII Immune Responses in Hemophilia a Mice with Pre-Existing Anti-FVIII Immunity

Cannabinoid Receptor Signaling As a Target for Personalized Therapy in Aggressive B Cell Lymphomas

Preclinical Evaluation of the Oral Proteasome Inhibitor Ixazomib in Diffuse Large B-Cell Lymphoma

Platelet-Targeted Gene Transfer Induces Immune Tolerance through Two Distinct Pathways

Immune Tolerance Developed in Platelet-Targeted FVIII Gene Therapy in Hemophilia Mice Is CD4 + T Cell-Mediated

The Impact of GPIba on the Efficacy of Platelet-Targeted FVIII Gene Therapy in Hemophilia a with Pre-Existing Anti-FVIII Immunity

High IDH1 Expression Is Associated with a Poor Prognosis in Cytogenetically Normal Acute Myeloid Leukemia

Prognostic Significance of Minimal Residual Disease in Adult Patients with B-Lineage Acute Lymphoblastic Leukemia by 8-Color Flow Cytometry

Serum 2-Hydroxyglutarate Level Is a Prognostic Marker in Acute Myeloid Leukemia

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American Society of Hematology

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