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Journal Articles

Platelet α IIb β 3 Receptor Antagonist Impedes the Hemostatic Efficacy of Platelet-Specific FVIII Gene Therapy in Hemophilia a Mice

Hongyin Yu, Jocelyn A. Schroeder, Jeremy Mattson, Qizhen Shi

Blood (2022) 140 (Supplement 1): 2712.

https://doi.org/10.1182/blood-2022-168343

Published: 2022

Journal Articles

Pre-Existing Anti-FVIII Immunity Alters Therapeutic Platelet-Targeted FVIII Engraftment in the System Preconditioned with Busulfan Alone through Cytotoxic CD8 T Cells

Weiqing Jing, Christina Baumgartner, Feng Xue, Jocelyn A. Schroeder, Qizhen Shi

Blood (2021) 138 (Supplement 1): 444.

https://doi.org/10.1182/blood-2021-153722

Published: 2021

Journal Articles

Platelet-Targeted Gene Therapy Induces Robust Immune Tolerance Even in a Primed Model Via Peripheral Clonal Deletion of CD4 and CD8 T Cells and Expansion of Treg Cells

Jing Li, MD PhD, Juan Chen, PhD, Jocelyn A. Schroeder, Qizhen Shi, MDPhD

Blood (2020) 136 (Supplement 1): 2.

https://doi.org/10.1182/blood-2020-140851

Published: 2020

Journal Articles

Fludarabine in Combination with Busulfan As Pretransplant Conditioning for Platelet Gene Therapy in Murine Hemophilia a with Inhibitors

Yingyu Chen, PhD, Jing Li, MD PhD, Jocelyn A. Schroeder, Weiqing Jing, MD PhD, Jianda Hu, PhD, Qizhen Shi, MD PhD

Blood (2019) 134 (Supplement_1): 1108.

https://doi.org/10.1182/blood-2019-127410

Published: 2019

Journal Articles

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

Weiqing Jing, MD PhD, Juan Chen, PhD, Yuanhua Cai, MD, Yingyu Chen, PhD, Jocelyn A. Schroeder, Weiguo Cui, MD PhD, Qizhen Shi, MD PhD

Blood (2019) 134 (Supplement_1): 92.

https://doi.org/10.1182/blood-2019-123777

Published: 2019

Journal Articles

In Vivo Enrichment of Genetically Manipulated Platelets for Murine Haemophilia B Gene Therapy

Yingyu Chen, PhD, Jocelyn A. Schroeder, Jianda Hu, PhD, Qizhen Shi, MD

Blood (2018) 132 (Supplement 1): 3483.

https://doi.org/10.1182/blood-2018-99-112245

Published: 2018

Journal Articles

Platelet-Targeted Hyperfunctional Factor IX (FIX) Gene Therapy for Hemophilia B Mice with Pre-Existing Anti-FIX Immunity

Jocelyn A. Schroeder, Jeremy G Mattson, Paul Edward Monahan, MD, Qizhen Shi, MD

Blood (2018) 132 (Supplement 1): 220.

https://doi.org/10.1182/blood-2018-99-111718

Published: 2018

Journal Articles

Platelet-Targeted Gene Transfer Prevents Graft Rejection and Induces Immune Tolerance Even in a Primed Model

Xiaofeng Luo, MD, PhD, Jing Li, MD PhD, Juan Chen, PhD, Jocelyn A. Schroeder, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 2315.

https://doi.org/10.1182/blood.V128.22.2315.2315

Published: 2016

Journal Articles

The Impact of VWF on FVIII Immune Responses in Hemophilia a Mice with Pre-Existing Anti-FVIII Immunity

Juan Chen, PhD, Jocelyn A. Schroeder, Xiaofeng Luo, MD PhD, Robert R. Montgomery, MD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 84.

https://doi.org/10.1182/blood.V128.22.84.84

Published: 2016

Journal Articles

Platelet-Derived Codon-Optimized Hyperfunctional FIX Gene Therapy of Hemophilia B Mice

Jocelyn A. Schroeder, Mary A. Jozwiak, Paul E. Monahan, MD, Qizhen Shi, MD PhD

Blood (2016) 128 (22): 3751.

https://doi.org/10.1182/blood.V128.22.3751.3751

Published: 2016

Journal Articles

The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity

Yingyu Chen, Jocelyn A. Schroeder, Juan Chen, Xiaofeng Luo, Christina K. Baumgartner, Robert R. Montgomery, Jianda Hu, Qizhen Shi

Blood (2016) 127 (10): 1346–1354.

https://doi.org/10.1182/blood-2015-08-662916

Published: 2016

Includes: Supplemental data

Journal Articles

Platelet-Targeted Gene Transfer Induces Antigen-Specific Immune Tolerance

Luo Xiaofeng, Jocelyn A. Schroeder, Christina Baumgartner, PhD, Juan Chen, Jianda Hu, MD PhD, Qizhen Shi, MD PhD

Blood (2014) 124 (21): 2154.

https://doi.org/10.1182/blood.V124.21.2154.2154

Published: 2014

Journal Articles

Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells

Qizhen Shi, Erin L. Kuether, Yingyu Chen, Jocelyn A. Schroeder, Scot A. Fahs, Robert R. Montgomery

Blood (2014) 123 (3): 395–403.

https://doi.org/10.1182/blood-2013-08-520478

Published: 2014

Includes: Supplemental data

Journal Articles

In Vivo Selection Of Genetically Manipulated Hematopoietic Stem Cells For Platelet Gene Therapy Of Hemophilia A

Qizhen Shi, Jocelyn A. Schroeder, David A. Wilcox, Robert R. Montgomery, Yingyu Chen

Blood (2013) 122 (21): 2329.

https://doi.org/10.1182/blood.V122.21.2329.2329

Published: 2013

Journal Articles

Lentivirus-Mediated Platelet Gene Therapy Corrects Bleeding Diathesis and Induces Immune Tolerance in Murine Hemophilia B Mice

Yingyu Chen, PhD, Jocelyn A. Schroeder, Erin L. Kuether, Guowei Zhang, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD

Blood (2012) 120 (21): 1101.

https://doi.org/10.1182/blood.V120.21.1101.1101

Published: 2012

Journal Articles

Targeting FVIII Expression to Human Platelets Corrects the Hemophilic Phenotype in An Immunocompromised Hemophilia A Mouse Model Transplanted with Genetically Manipulated Human Cord Blood Stem Cells

Qizhen Shi, MD, PhD, Erin L. Kuether, Scot A. Fahs, Jocelyn A. Schroeder, Robert R. Montgomery, MD

Blood (2011) 118 (21): 20.

https://doi.org/10.1182/blood.V118.21.20.20

Published: 2011

Journal Articles

Targeting FVIII Expression to Platelets Induces Immune Tolerance in Hemophilia A Mice with or without Pre-Existing Anti-FVIII Immunity,

Yingyu Chen, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Robert R. Montgomery, MD, David W. Scott, PhD, Qizhen Shi, MD, PhD

Blood (2011) 118 (21): 4170.

https://doi.org/10.1182/blood.V118.21.4170.4170

Published: 2011

Journal Articles

Factor VIII Inhibitors: Von Willebrand Factor Makes A Difference In Vitro and In Vivo

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Crystal L. Perry, Scot A. Fahs, Robert R. Montgomery, MD

Blood (2010) 116 (21): 709.

https://doi.org/10.1182/blood.V116.21.709.709

Published: 2010

Journal Articles

Correction of Murine Bernard Soulier Syndrome by Lentivirus-Mediated Gene Therapy

Sachiko Kanaji, MD, PhD, Erin L. Kuether, Scot A. Fahs, Jocelyn A. Schroeder, Jerry Ware, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD

Blood (2010) 116 (21): 552.

https://doi.org/10.1182/blood.V116.21.552.552

Published: 2010

Journal Articles

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Scot A. Fahs, David A. Wilcox, PhD, Robert R. Montgomery, MD

Blood (2010) 116 (21): 2201.

https://doi.org/10.1182/blood.V116.21.2201.2201

Published: 2010

NARROW

Platelet α IIb β 3 Receptor Antagonist Impedes the Hemostatic Efficacy of Platelet-Specific FVIII Gene Therapy in Hemophilia a Mice

Pre-Existing Anti-FVIII Immunity Alters Therapeutic Platelet-Targeted FVIII Engraftment in the System Preconditioned with Busulfan Alone through Cytotoxic CD8 T Cells

Platelet-Targeted Gene Therapy Induces Robust Immune Tolerance Even in a Primed Model Via Peripheral Clonal Deletion of CD4 and CD8 T Cells and Expansion of Treg Cells

Fludarabine in Combination with Busulfan As Pretransplant Conditioning for Platelet Gene Therapy in Murine Hemophilia a with Inhibitors

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

In Vivo Enrichment of Genetically Manipulated Platelets for Murine Haemophilia B Gene Therapy

Platelet-Targeted Hyperfunctional Factor IX (FIX) Gene Therapy for Hemophilia B Mice with Pre-Existing Anti-FIX Immunity

Platelet-Targeted Gene Transfer Prevents Graft Rejection and Induces Immune Tolerance Even in a Primed Model

The Impact of VWF on FVIII Immune Responses in Hemophilia a Mice with Pre-Existing Anti-FVIII Immunity

Platelet-Derived Codon-Optimized Hyperfunctional FIX Gene Therapy of Hemophilia B Mice

The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity

Platelet-Targeted Gene Transfer Induces Antigen-Specific Immune Tolerance

Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells

In Vivo Selection Of Genetically Manipulated Hematopoietic Stem Cells For Platelet Gene Therapy Of Hemophilia A

Lentivirus-Mediated Platelet Gene Therapy Corrects Bleeding Diathesis and Induces Immune Tolerance in Murine Hemophilia B Mice

Targeting FVIII Expression to Human Platelets Corrects the Hemophilic Phenotype in An Immunocompromised Hemophilia A Mouse Model Transplanted with Genetically Manipulated Human Cord Blood Stem Cells

Targeting FVIII Expression to Platelets Induces Immune Tolerance in Hemophilia A Mice with or without Pre-Existing Anti-FVIII Immunity,

Factor VIII Inhibitors: Von Willebrand Factor Makes A Difference In Vitro and In Vivo

Correction of Murine Bernard Soulier Syndrome by Lentivirus-Mediated Gene Therapy

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

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American Society of Hematology

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American Society of Hematology

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