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Erin L. Kuether
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Journal Articles

Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells

Qizhen Shi, Erin L. Kuether, Yingyu Chen, Jocelyn A. Schroeder, Scot A. Fahs, Robert R. Montgomery
Journal: Blood
Blood (2014) 123 (3): 395–403.
https://doi.org/10.1182/blood-2013-08-520478
Published: 2014
Includes: Supplemental data
Journal Articles

Lentivirus-Mediated Platelet Gene Therapy Corrects Bleeding Diathesis and Induces Immune Tolerance in Murine Hemophilia B Mice

Yingyu Chen, PhD, Jocelyn A. Schroeder, Erin L. Kuether, Guowei Zhang, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1101.
https://doi.org/10.1182/blood.V120.21.1101.1101
Published: 2012
Journal Articles

Targeting FVIII Expression to Human Platelets Corrects the Hemophilic Phenotype in An Immunocompromised Hemophilia A Mouse Model Transplanted with Genetically Manipulated Human Cord Blood Stem Cells

Qizhen Shi, MD, PhD, Erin L. Kuether, Scot A. Fahs, Jocelyn A. Schroeder, Robert R. Montgomery, MD
Journal: Blood
Blood (2011) 118 (21): 20.
https://doi.org/10.1182/blood.V118.21.20.20
Published: 2011
Journal Articles

Targeting FVIII Expression to Platelets Induces Immune Tolerance in Hemophilia A Mice with or without Pre-Existing Anti-FVIII Immunity,

Yingyu Chen, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Robert R. Montgomery, MD, David W. Scott, PhD, Qizhen Shi, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4170.
https://doi.org/10.1182/blood.V118.21.4170.4170
Published: 2011
Journal Articles

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Scot A. Fahs, David A. Wilcox, PhD, Robert R. Montgomery, MD
Journal: Blood
Blood (2010) 116 (21): 2201.
https://doi.org/10.1182/blood.V116.21.2201.2201
Published: 2010
Journal Articles

Factor VIII Inhibitors: Von Willebrand Factor Makes A Difference In Vitro and In Vivo

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Crystal L. Perry, Scot A. Fahs, Robert R. Montgomery, MD
Journal: Blood
Blood (2010) 116 (21): 709.
https://doi.org/10.1182/blood.V116.21.709.709
Published: 2010
Journal Articles

Correction of Murine Bernard Soulier Syndrome by Lentivirus-Mediated Gene Therapy

Sachiko Kanaji, MD, PhD, Erin L. Kuether, Scot A. Fahs, Jocelyn A. Schroeder, Jerry Ware, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 552.
https://doi.org/10.1182/blood.V116.21.552.552
Published: 2010
Journal Articles

Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A

Qizhen Shi, Scot A. Fahs, Erin L. Kuether, Brian C. Cooley, Hartmut Weiler, Robert R. Montgomery
Journal: Blood
Blood (2010) 116 (16): 3049–3057.
https://doi.org/10.1182/blood-2010-03-272419
Published: 2010
Journal Articles

Factor IX ectopically expressed in platelets can be stored in α-granules and corrects the phenotype of hemophilia B mice

Guowei Zhang, Qizhen Shi, Scot A. Fahs, Erin L. Kuether, Christopher E. Walsh, Robert R. Montgomery
Journal: Blood
Blood (2010) 116 (8): 1235–1243.
https://doi.org/10.1182/blood-2009-11-255612
Published: 2010
Includes: Supplemental data
Journal Articles

Intraperitoneal Injection and Recovery of VWF and FVIII and Differences From Intravenous and Subcutaneous Injection.

Qizhen Shi, MD, PhD, Erin L. Kuether, Guowei Zhang, PhD, Jocelyn A. Schroeder, Scot A. Fahs, Robert R. Montgomery, MD
Journal: Blood
Blood (2009) 114 (22): 3178.
https://doi.org/10.1182/blood.V114.22.3178.3178
Published: 2009
Journal Articles

Sustained Phenotypic Correction of Murine Hemophilia A with Pre-Existing Anti-FVIII Immunity Using Lentivirus-Mediated Platelet-Specific FVIII Gene Transfer.

Qizhen Shi, MD, PhD, Erin L. Kuether, Brian C. Cooley, Ph.D., Scot A. Fahs, Jocelyn A. Schroeder, David A. Wilcox, PhD, Robert R. Montgomery, MD
Journal: Blood
Blood (2009) 114 (22): 29.
https://doi.org/10.1182/blood.V114.22.29.29
Published: 2009
Journal Articles

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity

Qizhen Shi, Scot A. Fahs, David A. Wilcox, Erin L. Kuether, Patricia A. Morateck, Nicole Mareno, Hartmut Weiler, Robert R. Montgomery
Journal: Blood
Blood (2008) 112 (7): 2713–2721.
https://doi.org/10.1182/blood-2008-02-138214
Published: 2008
Journal Articles

The Effect of von Willebrand Factor (VWF) on Site-Specific Factor VIII (FVIII) Expression in Hemophilia A Mice.

Qizhen Shi, Scot A. Fahs, Erin L. Kuether, Robert R. Montgomery
Journal: Blood
Blood (2007) 110 (11): 764.
https://doi.org/10.1182/blood.V110.11.764.764
Published: 2007
Journal Articles

In the Presence of Pre-Existing Factor VIII (FVIII) Immunity, Hematopoietic Stem Cells (HSC) That Are Genetically Modified To Express FVIII in Platelets Were Successfully Transplanted into Hemophilic Mice under Myeloablative and Various Non-Myeloablative Conditions.

Qizhen Shi, Scot A. Fahs, David A. Wilcox, Erin L. Kuether, Hartmut Weiler, Robert R. Montgomery
Journal: Blood
Blood (2007) 110 (11): 768.
https://doi.org/10.1182/blood.V110.11.768.768
Published: 2007