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Journal Articles

A Murine Model of Type 2N VWD Was Developed By CRISPR/Cas9 Gene Editing and Recapitulates Human Type 2N VWD

Robert R Montgomery, MD, Scot A Fahs, Jeremy G Mattson, Hartmut Weiler, PhD, Qizhen Shi, MD

Blood (2018) 132 (Supplement 1): 221.

https://doi.org/10.1182/blood-2018-99-110324

Published: 2018

Journal Articles

The Severe Spontaneous Bleeding Phenotype in a Novel Hemophilia a Rat Model with an Inversion Mutation Is Rescued By Platelet-Targeted FVIII Expression

Qizhen Shi, MD, Jeremy G Mattson, Scot A Fahs, Robert R Montgomery, MD

Blood (2018) 132 (Supplement 1): 219.

https://doi.org/10.1182/blood-2018-99-112165

Published: 2018

Journal Articles

Von Willebrand Factor Binding to Myosin Assists in Coagulation

Veronica H Flood, MD, Tricia L Slobodianuk, BS, Daniel A Keesler, BS, Hannah Lohmeier, Scot A Fahs, Robert R Montgomery, MD

Blood (2018) 132 (Supplement 1): 22.

https://doi.org/10.1182/blood-2018-99-113105

Published: 2018

Journal Articles

Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis

Sachiko Kanaji, MD PhD, Jennifer N Orje, Yuichi Kamikubo, PhD, Taisuke Kanaji, MD PhD, Jeremy Mattson, Alessandro Zarpellon, PhD, Scot A. Fahs, Rashmi Sood, PhD, Sandra L Haberichter, PhD, Zaverio M. Ruggeri, MD, Robert R Montgomery, MD

Blood (2016) 128 (22): 558.

https://doi.org/10.1182/blood.V128.22.558.558

Published: 2016

Journal Articles

A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII

Scot A. Fahs, Matthew T. Hille, Qizhen Shi, Hartmut Weiler, Robert R. Montgomery

Blood (2014) 123 (24): 3706–3713.

https://doi.org/10.1182/blood-2014-02-555151

Published: 2014

Journal Articles

Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells

Qizhen Shi, Erin L. Kuether, Yingyu Chen, Jocelyn A. Schroeder, Scot A. Fahs, Robert R. Montgomery

Blood (2014) 123 (3): 395–403.

https://doi.org/10.1182/blood-2013-08-520478

Published: 2014

Includes: Supplemental data

Journal Articles

Transcriptional Analysis Of a Tissue-Specific Factor VIII Knockout Model Demonstrates The Importance Of Endothelial Factor VIII Synthesis

Scot A. Fahs, Matthew T. Hille, Robert R. Montgomery, MD

Blood (2013) 122 (21): 27.

https://doi.org/10.1182/blood.V122.21.27.27

Published: 2013

Journal Articles

Bleeding Phenotype of Murine Bernard Soulier Syndrome Is Potentially Corrected by Non-Myeloablative Hematopoietic Stem Cell Transplantation

Sachiko Kanaji, MD, PhD, Scot A. Fahs, Jerry Ware, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD

Blood (2012) 120 (21): 3340.

https://doi.org/10.1182/blood.V120.21.3340.3340

Published: 2012

Journal Articles

Targeting FVIII Expression to Human Platelets Corrects the Hemophilic Phenotype in An Immunocompromised Hemophilia A Mouse Model Transplanted with Genetically Manipulated Human Cord Blood Stem Cells

Qizhen Shi, MD, PhD, Erin L. Kuether, Scot A. Fahs, Jocelyn A. Schroeder, Robert R. Montgomery, MD

Blood (2011) 118 (21): 20.

https://doi.org/10.1182/blood.V118.21.20.20

Published: 2011

Journal Articles

Factor VIII Inhibitors: Von Willebrand Factor Makes A Difference In Vitro and In Vivo

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Crystal L. Perry, Scot A. Fahs, Robert R. Montgomery, MD

Blood (2010) 116 (21): 709.

https://doi.org/10.1182/blood.V116.21.709.709

Published: 2010

Journal Articles

Correction of Murine Bernard Soulier Syndrome by Lentivirus-Mediated Gene Therapy

Sachiko Kanaji, MD, PhD, Erin L. Kuether, Scot A. Fahs, Jocelyn A. Schroeder, Jerry Ware, PhD, Robert R. Montgomery, MD, Qizhen Shi, MD, PhD

Blood (2010) 116 (21): 552.

https://doi.org/10.1182/blood.V116.21.552.552

Published: 2010

Journal Articles

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

Qizhen Shi, MD, PhD, Erin L. Kuether, Jocelyn A. Schroeder, Scot A. Fahs, David A. Wilcox, PhD, Robert R. Montgomery, MD

Blood (2010) 116 (21): 2201.

https://doi.org/10.1182/blood.V116.21.2201.2201

Published: 2010

Journal Articles

Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A

Qizhen Shi, Scot A. Fahs, Erin L. Kuether, Brian C. Cooley, Hartmut Weiler, Robert R. Montgomery

Blood (2010) 116 (16): 3049–3057.

https://doi.org/10.1182/blood-2010-03-272419

Published: 2010

Journal Articles

Factor IX ectopically expressed in platelets can be stored in α-granules and corrects the phenotype of hemophilia B mice

Guowei Zhang, Qizhen Shi, Scot A. Fahs, Erin L. Kuether, Christopher E. Walsh, Robert R. Montgomery

Blood (2010) 116 (8): 1235–1243.

https://doi.org/10.1182/blood-2009-11-255612

Published: 2010

Includes: Supplemental data

Journal Articles

Intraperitoneal Injection and Recovery of VWF and FVIII and Differences From Intravenous and Subcutaneous Injection.

Qizhen Shi, MD, PhD, Erin L. Kuether, Guowei Zhang, PhD, Jocelyn A. Schroeder, Scot A. Fahs, Robert R. Montgomery, MD

Blood (2009) 114 (22): 3178.

https://doi.org/10.1182/blood.V114.22.3178.3178

Published: 2009

Journal Articles

Sustained Phenotypic Correction of Murine Hemophilia A with Pre-Existing Anti-FVIII Immunity Using Lentivirus-Mediated Platelet-Specific FVIII Gene Transfer.

Qizhen Shi, MD, PhD, Erin L. Kuether, Brian C. Cooley, Ph.D., Scot A. Fahs, Jocelyn A. Schroeder, David A. Wilcox, PhD, Robert R. Montgomery, MD

Blood (2009) 114 (22): 29.

https://doi.org/10.1182/blood.V114.22.29.29

Published: 2009

Journal Articles

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity

Qizhen Shi, Scot A. Fahs, David A. Wilcox, Erin L. Kuether, Patricia A. Morateck, Nicole Mareno, Hartmut Weiler, Robert R. Montgomery

Blood (2008) 112 (7): 2713–2721.

https://doi.org/10.1182/blood-2008-02-138214

Published: 2008

Journal Articles

Ectopic Expression of Human FIX in Mouse Platelets Can Store Releasable FIX in Platelets and May Be a Potential Strategy for Gene Therapy of Hemophilia B.

Guowei Zhang, Qizhen Shi, Scot A. Fahs, Christopher E. Walsh, Robert R. Montgomery

Blood (2007) 110 (11): 196.

https://doi.org/10.1182/blood.V110.11.196.196

Published: 2007

Journal Articles

The Effect of von Willebrand Factor (VWF) on Site-Specific Factor VIII (FVIII) Expression in Hemophilia A Mice.

Qizhen Shi, Scot A. Fahs, Erin L. Kuether, Robert R. Montgomery

Blood (2007) 110 (11): 764.

https://doi.org/10.1182/blood.V110.11.764.764

Published: 2007

Journal Articles

In the Presence of Pre-Existing Factor VIII (FVIII) Immunity, Hematopoietic Stem Cells (HSC) That Are Genetically Modified To Express FVIII in Platelets Were Successfully Transplanted into Hemophilic Mice under Myeloablative and Various Non-Myeloablative Conditions.

Qizhen Shi, Scot A. Fahs, David A. Wilcox, Erin L. Kuether, Hartmut Weiler, Robert R. Montgomery

Blood (2007) 110 (11): 768.

https://doi.org/10.1182/blood.V110.11.768.768

Published: 2007

NARROW

A Murine Model of Type 2N VWD Was Developed By CRISPR/Cas9 Gene Editing and Recapitulates Human Type 2N VWD

The Severe Spontaneous Bleeding Phenotype in a Novel Hemophilia a Rat Model with an Inversion Mutation Is Rescued By Platelet-Targeted FVIII Expression

Von Willebrand Factor Binding to Myosin Assists in Coagulation

Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis

A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII

Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells

Transcriptional Analysis Of a Tissue-Specific Factor VIII Knockout Model Demonstrates The Importance Of Endothelial Factor VIII Synthesis

Bleeding Phenotype of Murine Bernard Soulier Syndrome Is Potentially Corrected by Non-Myeloablative Hematopoietic Stem Cell Transplantation

Targeting FVIII Expression to Human Platelets Corrects the Hemophilic Phenotype in An Immunocompromised Hemophilia A Mouse Model Transplanted with Genetically Manipulated Human Cord Blood Stem Cells

Factor VIII Inhibitors: Von Willebrand Factor Makes A Difference In Vitro and In Vivo

Correction of Murine Bernard Soulier Syndrome by Lentivirus-Mediated Gene Therapy

The Important Role of Von Willebrand Factor In Platelet-Derived FVIII Gene Therapy of Murine Hemophilia A In the Presence of Inhibitors

Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A

Factor IX ectopically expressed in platelets can be stored in α-granules and corrects the phenotype of hemophilia B mice

Intraperitoneal Injection and Recovery of VWF and FVIII and Differences From Intravenous and Subcutaneous Injection.

Sustained Phenotypic Correction of Murine Hemophilia A with Pre-Existing Anti-FVIII Immunity Using Lentivirus-Mediated Platelet-Specific FVIII Gene Transfer.

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity

Ectopic Expression of Human FIX in Mouse Platelets Can Store Releasable FIX in Platelets and May Be a Potential Strategy for Gene Therapy of Hemophilia B.

The Effect of von Willebrand Factor (VWF) on Site-Specific Factor VIII (FVIII) Expression in Hemophilia A Mice.

In the Presence of Pre-Existing Factor VIII (FVIII) Immunity, Hematopoietic Stem Cells (HSC) That Are Genetically Modified To Express FVIII in Platelets Were Successfully Transplanted into Hemophilic Mice under Myeloablative and Various Non-Myeloablative Conditions.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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