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Julie Di Paolo
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Journal Articles

Phase 2 study of idelalisib and entospletinib: pneumonitis limits combination therapy in relapsed refractory CLL and NHL

Free
Clinical Trials & Observations Brief Report
Paul M. Barr, Gene B. Saylors, Stephen E. Spurgeon, Bruce D. Cheson, Daniel R. Greenwald, Susan M. O’Brien, Andre K. D. Liem, Rosemary E. Mclntyre, Adarsh Joshi, Esteban Abella-Dominicis, Michael J. Hawkins, Anita Reddy, Julie Di Paolo, Hank Lee, Joyce He, Jing Hu, Lyndah K. Dreiling, Jonathan W. Friedberg
Journal: Blood
Blood (2016) 127 (20): 2411–2415.
https://doi.org/10.1182/blood-2015-12-683516
Published: 2016
Includes: Supplemental data
Journal Articles

The Combination of Entospletinib and Vincristine Demonstrates Synergistic Activity in a Broad Panel of Hematological Cancer Cell Lines and Anti-Tumor Efficacy in a DLBCL Xenograft Model

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Mark Joseph Axelrod, PhD, Peter Fowles, Jeff Silverman, PhD, Astrid Clarke, PhD, Jennifer Tang, Emma Rousseau, M.S., Heather Kay Webb, PhD, Julie Di Paolo, PhD
Journal: Blood
Blood (2015) 126 (23): 5123.
https://doi.org/10.1182/blood.V126.23.5123.5123
Published: 2015
Journal Articles

Phase 2 Trial of Entospletinib (GS-9973), a Selective Syk Inhibitor, in Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL)

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Jeff P. Sharman, MD, Leonard M. Klein, MD, Michael Boxer, MD, Kathryn S. Kolibaba, MD, Steve Abella, MD, Julie Di Paolo, PhD, Clarence Eng, MPH, Jing Hu, PhD, Jing He, Anita Reddy, PhD, Christopher A. Yasenchak, MD
Journal: Blood
Blood (2015) 126 (23): 4152.
https://doi.org/10.1182/blood.V126.23.4152.4152
Published: 2015
Journal Articles

Combination Effects of B Cell Receptor Pathway Inhibitors (Entospletinib, ONO/GS-4059, and Idelalisib) and a BCL-2 Inhibitor in Primary CLL Cells

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Randall Jones, B.A., Mark Joseph Axelrod, PhD, Daniel Tumas, PhD DVM, Christophe Quéva, PhD, Julie Di Paolo, PhD
Journal: Blood
Blood (2015) 126 (23): 1749.
https://doi.org/10.1182/blood.V126.23.1749.1749
Published: 2015
Journal Articles

A Potential Therapeutic Strategy for Chronic Lymphocytic Leukemia by Combining GS-1101, a PI3 kinase Delta (PI3Kδ) Inhibitor and a Novel Highly Selective Spleen Tyrosine Kinase (Syk) Inhibitor, GS-9973

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Russell T Burke, Astrid Clarke, Sarah A Meadows, Marc M Loriaux, MD, PhD, Jennifer B Dunlap, MD, Guang Fan, MD, PhD, Patricia Maciejewski, Julie Di Paolo, Brian J. Lannutti, PhD, Brian J. Druker, Stephen E Spurgeon, MD
Journal: Blood
Blood (2012) 120 (21): 3876.
https://doi.org/10.1182/blood.V120.21.3876.3876
Published: 2012