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Journal Articles

Potential for Cure by Chemotherapy Only, without Allogeneic Stem Cell Transplantation, in Pediatric Relapsed Acute Myeloid Leukemia?.

Gertjan J. Kaspers, MD, PhD, Bianca F. Goemans, MD, PhD, Carin Korbijn, Rienk Y. Tamminga, MD, PhD, Karel Hählen, MD, PhD

Blood (2007) 110 (11): 2865.

https://doi.org/10.1182/blood.V110.11.2865.2865

Published: 2007

Journal Articles

Addition of PTK787/ZK 222584 Can Lower the Dosage of Amsacrine To Achieve Equal Amounts of AML Cell Death.

Alida C. Weidenaar, Hendrik J.M. de Jonge, Vaclav Fidler, PhD, Arja ter Elst, PhD, Tiny Meeuwsen, Jenny Douwes, Jessica C.A. Bouma, PhD, Karel Hählen, MD/PhD, Willem A. Kamps, MD/PhD, Evelina S. de Bont, MD/PhD

Blood (2007) 110 (11): 4199.

https://doi.org/10.1182/blood.V110.11.4199.4199

Published: 2007

Journal Articles

Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?

Christian Michel Zwaan, Monique L. den Boer, Karin M. Kazemier, Karel Hählen, Anne H. Loonen, Dirk Reinhardt, Ursula Creutzig, Gertjan J. L. Kaspers, Rob Pieters

Blood (2006) 107 (12): 4975–4977.

https://doi.org/10.1182/blood-2006-01-0309

Published: 2006

Journal Articles

In vitro profiling of the sensitivity of pediatric leukemia cells to tipifarnib: identification of T-cell ALL and FAB M5 AML as the most sensitive subsets

Bianca F. Goemans, Christian M. Zwaan, Amy Harlow, Anne H. Loonen, Brenda E. S. Gibson, Karel Hählen, Dirk Reinhardt, Ursula Creutzig, Michael C. Heinrich, Gertjan J. L. Kaspers

Blood (2005) 106 (10): 3532–3537.

https://doi.org/10.1182/blood-2005-04-1640

Published: 2005

Journal Articles

In-Vitro Cytotoxicity of Tipifarnib (Zarnestra TM) in Pediatric AML and ALL Samples Is Independent of RAS Mutations.

Bianca F. Goemans, MD, Christian M. Zwaan, MD, PhD, Gertjan J.L. Kaspers, MD, PhD, Karel Hählen, MD, Dirk Reinhardt, MD, PhD, Ursula Creutzig, MD, PhD, Michael C. Heinrich, MD

Blood (2004) 104 (11): 1172.

https://doi.org/10.1182/blood.V104.11.1172.1172

Published: 2004

Journal Articles

FLT3/Internal Tandem Duplication in Paired Presentation and Relapse Pediatric AML Samples.

Jacqueline Cloos, PhD, Christian M. Zwaan, MD, PhD, Sophie L. Corthals, Bianca F. Goemans, MD, Quinten Waisfisz, PhD, Ursula Creutzig, MD, PhD, Dirk Reinhardt, MD, PhD, Karel Hählen, MD, PhD, Gertjan J.L. Kaspers, MD, PhD

Blood (2004) 104 (11): 94.

https://doi.org/10.1182/blood.V104.11.94.94

Published: 2004

Journal Articles

CNS-Involvement in Pediatric Acute Myeloid Leukemia: Role of Low Blast Count and Traumatic Lumbar Puncture. A Dutch Childhood Oncology Group (DCOG) Study.

Christian M. Zwaan, MD, PhD, Wendy M.L.C. Nix, MD, Karel Hählen, MD, PhD, Elisabeth Van Wering, MD, PhD

Blood (2004) 104 (11): 1807.

https://doi.org/10.1182/blood.V104.11.1807.1807

Published: 2004

Journal Articles

FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance

Christian M. Zwaan, Soheil Meshinchi, Jerald P. Radich, Anjo J. P. Veerman, Dieuwke R. Huismans, Leonhard Munske, Martina Podleschny, Karel Hählen, Rob Pieters, Martin Zimmermann, Dirk Reinhardt, Jochen Harbott, Ursula Creutzig, Gertjan J. L. Kaspers, Frank Griesinger

Blood (2003) 102 (7): 2387–2394.

https://doi.org/10.1182/blood-2002-12-3627

Published: 2003

Journal Articles

Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities

Christian M. Zwaan, Gertjan J. L. Kaspers, Rob Pieters, Karel Hählen, Dieuwke R. Huismans, Martin Zimmermann, Jochen Harbott, Rosalyn M. Slater, Ursala Creutzig, Anjo J. P. Veerman

Blood (2002) 100 (9): 3352–3360.

https://doi.org/10.1182/blood.V100.9.3352

Published: 2002

Journal Articles

Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome

Christian M. Zwaan, Gertjan J. L. Kaspers, Rob Pieters, Karel Hählen, Gritta E. Janka-Schaub, Christina H. van Zantwijk, Dieuwke R. Huismans, Esther de Vries, Marianne G. Rots, Godefridus J. Peters, Gerrit Jansen, Ursula Creutzig, Anjo J. P. Veerman

Blood (2002) 99 (1): 245–251.

https://doi.org/10.1182/blood.V99.1.245

Published: 2002

Journal Articles

Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia

Christian M. Zwaan, Gert-Jan L. Kaspers, Rob Pieters, Nicole L. Ramakers-Van Woerden, Monique L. den Boer, Renate Wünsche, Maria M. A. Rottier, Karel Hählen, Elizabeth R. van Wering, Gritta E. Janka-Schaub, Ursula Creutzig, Anjo J. P. Veerman

Blood (2000) 96 (8): 2879–2886.

https://doi.org/10.1182/blood.V96.8.2879

Published: 2000

Journal Articles

TEL/AML1 gene fusion is related to in vitro drug sensitivity forl-asparaginase in childhood acute lymphoblastic leukemia

Nicole L. Ramakers-van Woerden, Rob Pieters, Annemarie H. Loonen, Isabelle Hubeek, Ellen van Drunen, H. Berna Beverloo, Rosalyn M. Slater, Jochen Harbott, Jeanette Seyfarth, Elisabeth R. van Wering, Karel Hählen, Kjeld Schmiegelow, Gritta E. Janka-Schaub, Anjo J. P. Veerman

Blood (2000) 96 (3): 1094–1099.

https://doi.org/10.1182/blood.V96.3.1094

Published: 2000

Journal Articles

Circumvention of Methotrexate Resistance in Childhood Leukemia Subtypes by Rationally Designed Antifolates

Marianne G. Rots, Rob Pieters, Godefridus J. Peters, Christina H. van Zantwijk, Rob Mauritz, Paul Noordhuis, James C. Willey, Karel Hählen, Ursula Creutzig, Gritta Janka-Schaub, Gertjan J.L. Kaspers, Anjo J.P. Veerman, Gerrit Jansen

Blood (1999) 94 (9): 3121–3128.

https://doi.org/10.1182/blood.V94.9.3121

Published: 1999

Journal Articles

Role of Folylpolyglutamate Synthetase and Folylpolyglutamate Hydrolase in Methotrexate Accumulation and Polyglutamylation in Childhood Leukemia

Marianne G. Rots, Rob Pieters, Godefridus J. Peters, Paul Noordhuis, Christina H. van Zantwijk, Gertjan J.L. Kaspers, Karel Hählen, Ursula Creutzig, Anjo J.P. Veerman, Gerrit Jansen

Blood (1999) 93 (5): 1677–1683.

https://doi.org/10.1182/blood.V93.5.1677

Published: 1999

NARROW

Potential for Cure by Chemotherapy Only, without Allogeneic Stem Cell Transplantation, in Pediatric Relapsed Acute Myeloid Leukemia?.

Addition of PTK787/ZK 222584 Can Lower the Dosage of Amsacrine To Achieve Equal Amounts of AML Cell Death.

Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?

In vitro profiling of the sensitivity of pediatric leukemia cells to tipifarnib: identification of T-cell ALL and FAB M5 AML as the most sensitive subsets

In-Vitro Cytotoxicity of Tipifarnib (Zarnestra TM) in Pediatric AML and ALL Samples Is Independent of RAS Mutations.

FLT3/Internal Tandem Duplication in Paired Presentation and Relapse Pediatric AML Samples.

CNS-Involvement in Pediatric Acute Myeloid Leukemia: Role of Low Blast Count and Traumatic Lumbar Puncture. A Dutch Childhood Oncology Group (DCOG) Study.

FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance

Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities

Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome

Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia

TEL/AML1 gene fusion is related to in vitro drug sensitivity forl-asparaginase in childhood acute lymphoblastic leukemia

Circumvention of Methotrexate Resistance in Childhood Leukemia Subtypes by Rationally Designed Antifolates

Role of Folylpolyglutamate Synthetase and Folylpolyglutamate Hydrolase in Methotrexate Accumulation and Polyglutamylation in Childhood Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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