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Paul Noordhuis
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Journal Articles

The Antibody-Drug Conjugate (ADC) IMGN779 Is Highly Active in Vitro and in Vivo Against Acute Myeloid Leukemia (AML) with FLT3-ITD Mutations

Kathleen R Whiteman, MS, Paul Noordhuis, PhD, Russell Walker, MS, Krystal Watkins, MS, Yelena Kovtun, PhD, Lauren Harvey, BS, Alan Wilhelm, BS, Holly Johnson, BS, Gerrit Jan Schuurhuis, PhD, Gert J Ossenkoppele, MD PhD, Robert J. Lutz, PhD
Journal: Blood
Blood (2014) 124 (21): 2321.
https://doi.org/10.1182/blood.V124.21.2321.2321
Published: 2014
Journal Articles

Specificity of Markers of Leukemia Initiating Cells with a New Multiparameter Flow Cytometry Based Appraoch; Impact for Prognostic and Therapeutic Applications

Gerrit J. Schuurhuis, PhD, Rolf Wouters, Angèle Kelder, Arjo P Rutten, Alexander N Snel, Monique Terwijn, Paul Noordhuis, PhD, Sonja Zweegman, MD, PhD, Gert J. Ossenkoppele, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1834.
https://doi.org/10.1182/blood.V116.21.1834.1834
Published: 2010
Journal Articles

Targeting of CLEC12A In Acute Myeloid Leukemia by Antibody-Drug-Conjugates and Bispecific CLL-1×CD3 BiTE Antibody

Paul Noordhuis, PhD, Monique Terwijn, Arjo P Rutten, Linda Smit, PhD, Gert J. Ossenkoppele, MD, PhD, Gerrit J. Schuurhuis, PhD
Journal: Blood
Blood (2010) 116 (21): 2890.
https://doi.org/10.1182/blood.V116.21.2890.2890
Published: 2010
Journal Articles

The value of fludarabine in addition to ARA-C and G-CSF in the treatment of patients with high-risk myelodysplastic syndromes and AML in elderly patients

Clinical Trials & Observations
Gert J. Ossenkoppele, Wilfried J. Graveland, Pieter Sonneveld, Simon M. G. J. Daenen, Douwe H. Biesma, Leo F. Verdonck, M. Ron Schaafsma, Petra H. M. Westveer, Godefridus J. Peters, Paul Noordhuis, Petra Muus, Dominik Selleslag, Bronnie van der Holt, Michel Delforge, Bob Löwenberg, Gregor E. G. Verhoef, Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON)
Journal: Blood
Blood (2004) 103 (8): 2908–2913.
https://doi.org/10.1182/blood-2003-07-2195
Published: 2004
Journal Articles

Differential mRNA expression of Ara-C–metabolizing enzymes explains Ara-C sensitivity in MLL gene–rearranged infant acute lymphoblastic leukemia

Clinical Trials & Observations
Ronald W. Stam, Monique L. den Boer, Jules P. P. Meijerink, Marli E. G. Ebus, Godefridus J. Peters, Paul Noordhuis, Gritta E. Janka-Schaub, Scott A. Armstrong, Stanley J. Korsmeyer, Rob Pieters
Journal: Blood
Blood (2003) 101 (4): 1270–1276.
https://doi.org/10.1182/blood-2002-05-1600
Published: 2003
Journal Articles

Circumvention of Methotrexate Resistance in Childhood Leukemia Subtypes by Rationally Designed Antifolates

Marianne G. Rots, Rob Pieters, Godefridus J. Peters, Christina H. van Zantwijk, Rob Mauritz, Paul Noordhuis, James C. Willey, Karel Hählen, Ursula Creutzig, Gritta Janka-Schaub, Gertjan J.L. Kaspers, Anjo J.P. Veerman, Gerrit Jansen
Journal: Blood
Blood (1999) 94 (9): 3121–3128.
https://doi.org/10.1182/blood.V94.9.3121
Published: 1999
Journal Articles

Role of Folylpolyglutamate Synthetase and Folylpolyglutamate Hydrolase in Methotrexate Accumulation and Polyglutamylation in Childhood Leukemia

Marianne G. Rots, Rob Pieters, Godefridus J. Peters, Paul Noordhuis, Christina H. van Zantwijk, Gertjan J.L. Kaspers, Karel Hählen, Ursula Creutzig, Anjo J.P. Veerman, Gerrit Jansen
Journal: Blood
Blood (1999) 93 (5): 1677–1683.
https://doi.org/10.1182/blood.V93.5.1677
Published: 1999
Journal Articles

Differential Methotrexate Resistance in Childhood T- Versus Common/PreB-Acute Lymphoblastic Leukemia Can Be Measured by an In Situ Thymidylate Synthase Inhibition Assay, But Not by the MTT Assay

Marianne G. Rots, Rob Pieters, Gert-Jan L. Kaspers, Christina H. van Zantwijk, Paul Noordhuis, Rob Mauritz, Anjo J.P. Veerman, Gerrit Jansen, Godefridus J. Peters
Journal: Blood
Blood (1999) 93 (3): 1067–1074.
https://doi.org/10.1182/blood.V93.3.1067
Published: 1999