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Journal Articles

Mitochondrial Fitness and Immune Function of Natural Killer Cells Are Impaired By the Multiple Myeloma (MM) Tumor Cells: The Role of MM Microenvironment Interactions

Katia Beider, Ilana Kalnitsky, Nira Varda-Bloom, Olga Ostrovsky, Avichai Shimoni, Hila Magen, Arnon Nagler

Blood (2023) 142 (Supplement 1): 875.

https://doi.org/10.1182/blood-2023-180516

Published: 2023

Journal Articles

CXCR4 Promotes Bortezomib Resistance and Regulates Metabolic Reprogramming, Activating Both Glycolytic and Oxphos Pathways in Multiple Myeloma

Katia Beider, Noy Sharvit Boaron, Valeria Voevoda, Olga Ostrovsky, Ivetta Danylesko, Avichai Shimoni, Amnon Peled, Arnon Nagler

Blood (2022) 140 (Supplement 1): 5969–5970.

https://doi.org/10.1182/blood-2022-164646

Published: 2022

Journal Articles

Venetoclax Reverses Metabolic Reprogramming Induced By S1P Modulator FTY720, Suppresses Oxidative Phosphorylation and Synergistically Targets Multiple Myeloma

Evgenia Rosenberg, Valeria Voevoda, Hila Magen, Olga Ostrovsky, Avichai Shimoni, Amnon Peled, Arnon Nagler, Katia Beider

Blood (2021) 138 (Supplement 1): 1195.

https://doi.org/10.1182/blood-2021-149372

Published: 2021

Journal Articles

Immunophenotyping and Function of Peripheral Blood Mononuclear Cells in Patients Undergoing Unrelated Allogeneic Transplantation with Post-Transplantation Cyclophosphamide in Combination with ATG Anti-Graft Versus Host Disease Prophylaxis

Katia Beider, Valeria Voevoda, Noga Shem-Tov, MD, Ronit Yerushalmi, MD, Ivetta Danilesko, MD, Ania Hava Grushchenko-Polaq, Olivia Devillers, Idit Wolf, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Arnon Nagler, MD MSc

Blood (2019) 134 (Supplement_1): 1989.

https://doi.org/10.1182/blood-2019-129619

Published: 2019

Journal Articles

Maintaining the Cellular Anti-Viral and Anti-Leukemic Activities in GvHD Patients Undergoing Extracorporeal Photophoresis Therapy

Ruben A. Gößmann, Lei Wang, MD, Ming Ni, Mingya Yang, MD, Thomas Luft, Ute Hegenbart, MD, Stefan O. Schönland, MD, Patrick Wuchter, MD, Volker Eckstein, William Hermann Krüger, MD PhD, Ronit Yerushalmi, MD, Katia Beider, Arnon Nagler, MD MSc, Carsten Müller-Tidow, MD, Peter Dreger, Michael Schmitt, MD, Anita Schmitt, MD

Blood (2019) 134 (Supplement_1): 3287.

https://doi.org/10.1182/blood-2019-125049

Published: 2019

Journal Articles

Upregulation of Senescent/Exhausted Phenotype of CAR T Cells and Induction of Both Treg and Myeloid Suppressive Cells Correlate with Reduced Response to CAR T Cell Therapy in Relapsed/Refractory B Cell Malignancies

Katia Beider, Michal J Besser, PhD, Jacob Schachter, MD, Ania Hava Grushchenko-Polaq, Valeria Voevoda, Idit Wolf, Olga Ostrovsky, PhD, Elad Jacoby, MD, Avichai Shimoni, MD, Arnon Nagler, MD MSc

Blood (2019) 134 (Supplement_1): 3234.

https://doi.org/10.1182/blood-2019-128068

Published: 2019

Journal Articles

Inhibition of WIP1 Phosphatase in Multiple Myeloma Overcomes Bortezomib Resistance and Promotes Cell Death Via ER Stress-Induced Apoptotic JNK/c-Jun Signaling and Downregulation of Inhibitors of Apoptosis Proteins (IAPs)

Katia Beider, Evgenia Rosenberg, Valeria Voevoda, Hanna Bitner, Yaarit Sirovsky, Hila Magen, MD, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Michael Milyavsky, PhD, Amnon Peled, Arnon Nagler, MD

Blood (2018) 132 (Supplement 1): 1366.

https://doi.org/10.1182/blood-2018-99-114652

Published: 2018

Journal Articles

Repeated Courses of Orally Administered Fecal Microbiota Transplantation for the Treatment of Steroid Resistant and Steroid Dependent Intestinal Acute Graft Vs. Host Disease: A Pilot Study (NCT 03214289)

Roni Shouval, MD PhD, Ilan Youngster, MD MSc, Mika Geva, MD, Adi Eshel, MSc, Ivetta Danylesko, MD, Avichai Shimoni, MD, Katia Beider, Joshua A Fein, Itai Sharon, PhD, Omry Koren, PhD, Arnon Nagler, MD

Blood (2018) 132 (Supplement 1): 2121.

https://doi.org/10.1182/blood-2018-99-110270

Published: 2018

Journal Articles

Blocking of Transient Receptor Potential Vanilloid1 (TRPV1) Promotes Lysosomal Destabilization and Enhances Bortezomib-Induced ER Stress and Cell Death Via HSP70 and LAMP3 Down-Regulation: Novel Therapeutic Target for Multiple Myeloma

Katia Beider, Valeria Voevoda, Hanna Bitner, Evgenia Rosenberg, Yaarit Sirovsky, Hila Magen, MD, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Zohar Bromberg, PhD, Amnon Peled, Arnon Nagler, MD

Blood (2017) 130 (Supplement 1): 804.

https://doi.org/10.1182/blood.V130.Suppl_1.804.804

Published: 2017

Journal Articles

The CXCR4 Antagonist BL-8040 Induces a Robust Mobilization of CD34+CD38−CD45RA−CD90+ CD49f+ HSCs with Long-Term and Secondary Myeloid and Lymphoid Repopulating Activity

Michal Abraham, PhD, Galia Oberkovitz, PhD, Baruch Bulvik, Klein Shiri, Hanna Wald, Orly Eizenberg, Katia Beider, Arnon Nagler, MD, Abi Vainstein, MD, Eyal Benami, Rotem Golan, Eithan Galun, Yoseph Caraco, Reuven Or, MD, Amnon Peled

Blood (2017) 130 (Supplement 1): 660.

https://doi.org/10.1182/blood.V130.Suppl_1.660.660

Published: 2017

Journal Articles

Functional rs4693608 SNP is Located into Strong Hpse Gene Intron Enhancer and Thereby Influences to the Ability of Nuclear Proteins Binding and Activity of This Enhancer in Broad Number of Hematological Cell Lines and ALL/AML Primary Samples

Olga Ostrovsky, PhD, Ania Hava Grushchenko Polaq, Katia Beider, PhD, Rita Mayorov, Avichai Shimoni, MD, Israel Vlodavsky, PhD, Arnon Nagler

Blood (2016) 128 (22): 3934.

https://doi.org/10.1182/blood.V128.22.3934.3934

Published: 2016

Journal Articles

The High Affinity CXCR4 Inhibitor, BL-8040, Induces Apoptosis of AML Blasts and Their Terminal Differentiation By Blocking AKT/ERK Survival Signals and Downregulating BCL-2, MCL-1 and Cyclin-D1 through Regulation of Mir-15a/16-1 Expression

Michal Abraham, PhD, Shiri Klein, Baruch Bulvik, Hanna Wald, Dvora Holam, Lola Weiss, Katia Beider, PhD, Orly Eizenberg, Ori Wald, MD PhD, Abraham Avigdor, MD, Ohad Benjamini, MD, Eithan Galun, MD, Arnon Nagler, Yaron Pereg, PhD, Amnon Peled, PhD

Blood (2016) 128 (22): 767.

https://doi.org/10.1182/blood.V128.22.767.767

Published: 2016

Journal Articles

The mTOR Inhibitor Everolimus Overcomes CXCR4-Mediated Resistance to HDAC Inhibitor Panobinostat through Inhibition of p21 and Mitosis Regulators, Sensitizing MM Cells to DNA-Damaged Induced Apoptosis

Katia Beider, PhD, Valeria Voevoda, Hanna Bitner, Evgenia Rosenberg, Hila Magen, MD, Olga Ostrovsky, PhD, Merav Leiba, MD, Noya Shilo, MD, Avichai Shimoni, MD, Michael Milyavsky, PhD, Amnon Peled, PhD, Arnon Nagler

Blood (2016) 128 (22): 891.

https://doi.org/10.1182/blood.V128.22.891.891

Published: 2016

Journal Articles

Distinct Roles of CHK2 and Cell Death in Suppressing Oncogenic Potential of Tandem DNA Breaks in Human Hematopoietic Stem Cells

Shahar Biechonski, M.Sc, Muhammad Yassin, Nasma Aqaqe, Leonid Olender, Melanie Rall, Lisa Wiesmüller, PhD, Yael Raz, MD PhD, Katia Beider, PhD, Arnon Nagler, Michael Milyavsky, PhD

Blood (2016) 128 (22): 2659.

https://doi.org/10.1182/blood.V128.22.2659.2659

Published: 2016

Journal Articles

Anti-Human T-Lymphocyte Immunoglobulin (ATG)-Induced T Regulatory Cells and Their Soluble Factors Suppress T Cell Proliferation: Potential Role in Allogeneic Stem Cell Transplantation

Katia Beider, PhD, David Naor, PhD, Valeria Voevoda, Olga Ostrovsky, PhD, Hanna Bitner, Evgenia Rosenberg, Nira Bloom, PhD, Simone Tal, Ivetta Danilesko, MD, Avichai Shimoni, MD, Arnon Nagler, MD MSc

Blood (2015) 126 (23): 1889.

https://doi.org/10.1182/blood.V126.23.1889.1889

Published: 2015

Journal Articles

S1P Modulator FTY720 Targets Multiple Myeloma Cell Proliferation and Stromal Interactions Via CXCR4/CXCL12 and mTOR Pathways

Katia Beider, PhD, Evgenia Rosenberg, Hanna Bitner, Merav Leiba, MD, Maya Koren-Michowitz, MD, Michal Abraham, PhD, Shiri Klein, Hanna Wald, Avichai Shimoni, MD, Amnon Peled, PhD, Arnon Nagler, MD

Blood (2014) 124 (21): 4707.

https://doi.org/10.1182/blood.V124.21.4707.4707

Published: 2014

Journal Articles

The International Multiple Myeloma Research (IMMEnSE) Consortium: Genetics of Multiple Myeloma Risk and Prognosis

Blood (2014) 124 (21): 3421.

https://doi.org/10.1182/blood.V124.21.3421.3421

Published: 2014

Journal Articles

The CXCR4 Antagonist BL-8040 Efficiently Induces Apoptosis and Inhibits The Survival Of AML Cells

Sigal Tavor, MD, Ido Weiss, Katia Beider, Ph.D., Hanna Wald, Orly Eizenberg, Yaron Pereg, Leah Klapper, Arnon Nagler, MD, MSc, Amnon Peled, Michal Abraham, PhD

Blood (2013) 122 (21): 3939.

https://doi.org/10.1182/blood.V122.21.3939.3939

Published: 2013

Journal Articles

Nilotinib Exhibits an in Vitro Antiviral Activity Against Human Cytomegalovirus (HCMV): Potential Clinical Applications

Dana Wolf, Esther Djian, Katia Beider, Avichai Shimoni, Arnon Nagler

Blood (2012) 120 (21): 4666.

https://doi.org/10.1182/blood.V120.21.4666.4666

Published: 2012

Journal Articles

Combination of Imatinib with CXCR4 Antagonist BKT140 Overcomes the Protective Effect of Stroma and Targets CML in Vitro and in Vivo

Katia Beider, Merav Darash-Yahana, Boaz Pal, Orly Blaier, Maya Koren-Michowitz, Michal Abraham, Hanna Wald, Orly Eizenberg, Amnon Peled, Arnon Nagler, MD

Blood (2012) 120 (21): 3735.

https://doi.org/10.1182/blood.V120.21.3735.3735

Published: 2012

NARROW

Mitochondrial Fitness and Immune Function of Natural Killer Cells Are Impaired By the Multiple Myeloma (MM) Tumor Cells: The Role of MM Microenvironment Interactions

CXCR4 Promotes Bortezomib Resistance and Regulates Metabolic Reprogramming, Activating Both Glycolytic and Oxphos Pathways in Multiple Myeloma

Venetoclax Reverses Metabolic Reprogramming Induced By S1P Modulator FTY720, Suppresses Oxidative Phosphorylation and Synergistically Targets Multiple Myeloma

Immunophenotyping and Function of Peripheral Blood Mononuclear Cells in Patients Undergoing Unrelated Allogeneic Transplantation with Post-Transplantation Cyclophosphamide in Combination with ATG Anti-Graft Versus Host Disease Prophylaxis

Maintaining the Cellular Anti-Viral and Anti-Leukemic Activities in GvHD Patients Undergoing Extracorporeal Photophoresis Therapy

Upregulation of Senescent/Exhausted Phenotype of CAR T Cells and Induction of Both Treg and Myeloid Suppressive Cells Correlate with Reduced Response to CAR T Cell Therapy in Relapsed/Refractory B Cell Malignancies

Inhibition of WIP1 Phosphatase in Multiple Myeloma Overcomes Bortezomib Resistance and Promotes Cell Death Via ER Stress-Induced Apoptotic JNK/c-Jun Signaling and Downregulation of Inhibitors of Apoptosis Proteins (IAPs)

Repeated Courses of Orally Administered Fecal Microbiota Transplantation for the Treatment of Steroid Resistant and Steroid Dependent Intestinal Acute Graft Vs. Host Disease: A Pilot Study (NCT 03214289)

Blocking of Transient Receptor Potential Vanilloid1 (TRPV1) Promotes Lysosomal Destabilization and Enhances Bortezomib-Induced ER Stress and Cell Death Via HSP70 and LAMP3 Down-Regulation: Novel Therapeutic Target for Multiple Myeloma

The CXCR4 Antagonist BL-8040 Induces a Robust Mobilization of CD34+CD38−CD45RA−CD90+ CD49f+ HSCs with Long-Term and Secondary Myeloid and Lymphoid Repopulating Activity

Functional rs4693608 SNP is Located into Strong Hpse Gene Intron Enhancer and Thereby Influences to the Ability of Nuclear Proteins Binding and Activity of This Enhancer in Broad Number of Hematological Cell Lines and ALL/AML Primary Samples

The High Affinity CXCR4 Inhibitor, BL-8040, Induces Apoptosis of AML Blasts and Their Terminal Differentiation By Blocking AKT/ERK Survival Signals and Downregulating BCL-2, MCL-1 and Cyclin-D1 through Regulation of Mir-15a/16-1 Expression

The mTOR Inhibitor Everolimus Overcomes CXCR4-Mediated Resistance to HDAC Inhibitor Panobinostat through Inhibition of p21 and Mitosis Regulators, Sensitizing MM Cells to DNA-Damaged Induced Apoptosis

Distinct Roles of CHK2 and Cell Death in Suppressing Oncogenic Potential of Tandem DNA Breaks in Human Hematopoietic Stem Cells

Anti-Human T-Lymphocyte Immunoglobulin (ATG)-Induced T Regulatory Cells and Their Soluble Factors Suppress T Cell Proliferation: Potential Role in Allogeneic Stem Cell Transplantation

S1P Modulator FTY720 Targets Multiple Myeloma Cell Proliferation and Stromal Interactions Via CXCR4/CXCL12 and mTOR Pathways

The International Multiple Myeloma Research (IMMEnSE) Consortium: Genetics of Multiple Myeloma Risk and Prognosis

The CXCR4 Antagonist BL-8040 Efficiently Induces Apoptosis and Inhibits The Survival Of AML Cells

Nilotinib Exhibits an in Vitro Antiviral Activity Against Human Cytomegalovirus (HCMV): Potential Clinical Applications

Combination of Imatinib with CXCR4 Antagonist BKT140 Overcomes the Protective Effect of Stroma and Targets CML in Vitro and in Vivo

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American Society of Hematology

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