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Ken CN Chang
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Journal Articles

Quantum-First Trial: FLT3 -ITD-Specific MRD Clearance Is Associated with Improved Overall Survival

Mark J. Levis, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E. Connolly Rohrbach, Ken CN Chang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Arnaud Lesegretain, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Alexander Perl
Journal: Blood
Blood (2022) 140 (Supplement 1): 546–548.
https://doi.org/10.1182/blood-2022-162739
Published: 2022
Journal Articles

Effect of Co-Mutations and FLT3 -ITD Variant Allele Frequency (VAF) on Response to Quizartinib or Salvage Chemotherapy (SC) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Alexander E. Perl, MD, Jorge E. Cortes, MD, Siddhartha Ganguly, MD, Samer K. Khaled, MD, Alwin Krämer, MD, Giovanni Martinelli, MD, Nigel H. Russell, MD, Ken CN Chang, PhD, Derek E. Mires, PharmD, Kazunobu Kato, MD PhD, Yufen Zhang, PhD, Sergey Korkhov, Zhenyu Wang, PhD, Tobias Günnel, PhD, Hiroyuki Sumi, PhD, Takeshi Isoyama, PhD, Arnaud Lesegretain, Flora Berisha, MS, Cedric E. Dos Santos, PhD, Mark J. Levis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 737.
https://doi.org/10.1182/blood-2019-121880
Published: 2019
Journal Articles

Development of a Novel Next-Generation Sequencing (NGS)-Based Assay for Measurable Residual Disease (MRD) in FLT3 -ITD AML and Its Potential Clinical Application in Patients Treated with Chemotherapy Plus FLT3 Inhibitors

Mark J. Levis, MD, Wenge Shi, PhD, Ken CN Chang, PhD, Christian Laing, PhD, Flora Berisha, MS, Emily Adams, BS, MB(ASCP)CM, Christopher D Gocke, MD, Wei Ding, PhD, Kenji Nakamaru, Jelveh Lameh, PhD, Reinhold Pollner, Ken Kobayashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1459.
https://doi.org/10.1182/blood-2018-99-110438
Published: 2018