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Kenneth Kulmatycki
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Journal Articles

Multiple Supratherapeutic Doses of Iptacopan 400 Mg Twice Daily Are Well Tolerated in Healthy Participants: Safety Findings from a Randomized, Participant-Blinded, Placebo-Controlled, Phase I Study

Robert L Schmouder, Melissa Hackling, Bharti Shah, S. Eralp Bellibas, Kenneth Kulmatycki
Journal: Blood
Blood (2024) 144 (Supplement 1): 5670.
https://doi.org/10.1182/blood-2024-198628
Published: 2024
Journal Articles

A First-in-Human, Phase 1 Study to Assess the Pharmacodynamic Properties of Single-Dose Iptacopan (CLNP023X2101)

Robert Schmouder, Guido Junge, Prasanna Kumar Nidamarthy, Kenneth Kulmatycki
Journal: Blood
Blood (2023) 142 (Supplement 1): 4096.
https://doi.org/10.1182/blood-2023-179655
Published: 2023
Journal Articles

A Phase 1 Study to Evaluate the Pharmacokinetics of Single High Doses of Iptacopan

Robert Schmouder, Noemi Kaetterer, Kenneth Kulmatycki, Prasanna Kumar Nidamarthy
Journal: Blood
Blood (2023) 142 (Supplement 1): 2723.
https://doi.org/10.1182/blood-2023-179012
Published: 2023
Journal Articles

A Phase 1 Study to Assess the Effect of Supratherapeutic Doses of Iptacopan on Cardiac Conduction Parameters and Safety

Robert Schmouder, Noemi Kaetterer, Kenneth Kulmatycki, Prasanna Kumar Nidamarthy
Journal: Blood
Blood (2023) 142 (Supplement 1): 5644.
https://doi.org/10.1182/blood-2023-179648
Published: 2023
Journal Articles

Dose-Exposure-Response Relationships of Biomarkers and Efficacy Measures with Iptacopan, a Complement Factor B Inhibitor, in Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) with or without Concomitant Anti-C5 Therapy

Antonio Risitano, Régis Peffault de Latour, Eng Soo Yap, Lily LL Wong, Bor-Sheng Ko, Sung-Soo Yoon, Alexander Roeth, Irina Baltcheva, Julie Milojevic, Niamh Fagan, Kenneth Kulmatycki, Prasanna K Nidamarthy, Guido Junge, Jun Ho Jang
Journal: Blood
Blood (2022) 140 (Supplement 1): 5803–5804.
https://doi.org/10.1182/blood-2022-160114
Published: 2022
Journal Articles

MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans

Alexander W. Koch, Nikolaus Schiering, Samu Melkko, Stefan Ewert, Janeen Salter, Yiming Zhang, Peter McCormack, Jianying Yu, Xueming Huang, Yu-Hsin Chiu, Zhiping Chen, Simone Schleeger, Geraldine Horny, Keith DiPetrillo, Lionel Muller, Andreas Hein, Frederic Villard, Meike Scharenberg, Paul Ramage, Ulrich Hassiepen, Serge Côté, Julie DeGagne, Carsten Krantz, Jörg Eder, Brian Stoll, Kenneth Kulmatycki, David L. Feldman, Peter Hoffmann, Craig T. Basson, Robert J. A. Frost, Yasser Khder
Journal: Blood
Blood (2019) 133 (13): 1507–1516.
https://doi.org/10.1182/blood-2018-10-880849
Published: 2019
Includes: Supplemental data