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Kristina M. Knapp, BS
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Journal Articles

Genomic Profiling Combining DNA and RNA Analysis of 112 Formalin-Fixed Paraffin-Embedded Diffuse Large B Cell Lymphoma Specimens Identifies a High Frequency of Clinically Relevant Genomic Alterations

Andrew M. Intlekofer, MD PhD, Patrick Hilden, MS, Venkatraman E. Seshan, PhD, Amanda R. Copeland, MSN, Ross L. Levine, MD, Andrew D. Zelenetz, MD PhD, Julie Teruya-Feldstein, MD, Ahmet Dogan, MD PhD, Maria Lia Palomba, MD, Craig H. Moskowitz, MD, Marcel R. M. van den Brink, MD PhD, Kristina M. Knapp, BS, Janine D. Pichardo, BS, Kristina W. Brennan, BS, Geneva Young, BS, Jie He, PhD, Michelle K. Nahas, PhD, Roman Yelensky, PhD, Geoff A. Otto, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Vincent A. Miller, MD, Anas Younes, MD
Journal: Blood
Blood (2014) 124 (21): 704.
https://doi.org/10.1182/blood.V124.21.704.704
Published: 2014
Journal Articles

Genomic Analysis of Serial Samples from CLL Patients Identifies Clonal Events Associated with Disease Progression

Jeffrey R Gardner, BS, MBA, Michelle Nahas, PhD, Jie He, PhD, Shlomzion Aumann, Mithat Gonen, Minal Patel, Kristina M. Knapp, BS, Maria Lia Palomba, MD, Roman Yelensky, PhD, Amy L Donahue, MS, Geoff Otto, PhD, Maria Arcila, MD, Nicole Lamanna, Mark G. Frattini, MD PhD, Ahmet Dogan, MD PhD, Jae H Park, MD, Doron Lipson, PhD, Martin S. Tallman, MD, Ross L. Levine, MD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD PhD, Mark L Heaney, MD PhD, Vincent A. Miller, MD, Andrew D. Zelenetz, MD PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 1954.
https://doi.org/10.1182/blood.V124.21.1954.1954
Published: 2014
Journal Articles

Patient Derived Xenograft (PDX) Models Recapitulate the Genomic-Driver Composition of Acute Leukemia Samples

Andrei V. Krivtsov, PhD, Xujun Wang, MD, Noushin Rahnamay Farnoud, PhD, Michael Hadler, MSc, Marta Sanchez Martin, Kristina M. Knapp, BS, Eytan M. Stein, Doron Lipson, PhD, Michelle K. Nahas, PhD, Philip J. Stephens, PhD, Eric M Sanford, BS, Kai Wang, MDPhD, Garrett M Frampton, PhD, Tim Brennan, PhD, Geoff A. Otto, PhD, Roman Yelensky, PhD, Vincent Miller, MD, Ross L. Levine, MD, Adolfo A. Ferrando, MD PhD, Scott A. Armstrong, MD PhD
Journal: Blood
Blood (2014) 124 (21): 286.
https://doi.org/10.1182/blood.V124.21.286.286
Published: 2014
Journal Articles

Utility of Combined DNA and RNA Next Generation Sequencing in Leukemias for Identification of Prognostic and Therapeutically Relevant Genomic Alterations in Clinical Practice

Catherine C. Coombs, MD, Aaron D. Viny, MD MS, Jie He, PhD, Rachel Kobos, MD, Doron Lipson, PhD, Neerav Shukla, MD, Kristina M. Knapp, BS, Geoff Otto, PhD, Omar Abdel-Wahab, MD, Eytan M. Stein, Raajit K. Rampal, MD PhD, Vincent A. Miller, MD, Ahmet Dogan, MD PhD, Marcel R.M. van den Brink, MD PhD, Scott A. Armstrong, MD PhD, Phil J Stephens, PhD, Martin S. Tallman, MD, Ross L. Levine, MD
Journal: Blood
Blood (2014) 124 (21): 1039.
https://doi.org/10.1182/blood.V124.21.1039.1039
Published: 2014
Journal Articles

Extensive High-Depth Sequencing Of Longitudinal CLL Samples Identifies Frequent Mutations In MAP Kinase Signaling and Novel Mutations Activating Notch and Beta-Catenin

Jeffrey R Gardner, MBA, Michelle K. Nahas, PhD, Jie He, PhD, Minal Patel, Kristina M. Knapp, BS, M. Lia Palomba, MD, Roman Yelensky, PhD, Amy L Donahue, MS, Geoff A. Otto, PhD, Maria Arcila, MD, Ahmet Dogan, MD, PhD, Jae H Park, MD, Andrew D. Zelenetz, MD, PhD, Doron Lipson, PhD, Martin S. Tallman, MD, Ross L. Levine, MD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD, PhD, Vincent A. Miller, MD, Mark L Heaney, MD, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2013) 122 (21): 2858.
https://doi.org/10.1182/blood.V122.21.2858.2858
Published: 2013
Journal Articles

Profiling Genomic Alterations Of Diffuse Large B-Cell Lymphoma (DLBCL) At Diagnosis, Relapse, and Transformation, Using a Novel Clinical Diagnostic Targeted Sequencing Platform

Andrew M. Intlekofer, MD, PhD, Venkatraman E. Sheshan, PhD, Ross L. Levine, MD, Andrew D. Zelenetz, MD, PhD, Julie Teruya-Feldstein, MD, Ahmet Dogan, MD, PhD, Maria Lia Palomba, MD, Craig H. Moskowitz, MD, Marcel R. M. van den Brink, MD, PhD, Kristina M. Knapp, BS, Amanda R. M. Copeland, MSN, Janine D. Pichardo, BS, Kristina W. Brennan, BS, Geneva Young, BS, Jie He, PhD, Michelle K. Nahas, PhD, Roman Yelensky, PhD, Geoff A. Otto, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Vincent A. Miller, MD, Anas Younes, MD
Journal: Blood
Blood (2013) 122 (21): 1761.
https://doi.org/10.1182/blood.V122.21.1761.1761
Published: 2013
Journal Articles

Comprehensive Mutational Profiling In Myelodysplastic Syndromes Treated With Decitabine and Tretinoin

Alan H. Shih, MD PhD, Sean M. Devlin, PhD, Emily K. Dolezal, Kristina M. Knapp, BS, Kai Wang, MD PhD, Eric M. Sanford, BS, Tim Brennan, PhD, Roman Yelensky, PhD, Michelle Nahas, PhD, Geoff A Otto, PhD, Doron Lipson, PhD, Philip J Stephens, PhD, Vincent Miller, MD, Marcel R.M. van den Brink, MD, PhD, Ross L. Levine, MD, Stephen Nimer, MD, Virginia M. Klimek, M.D
Journal: Blood
Blood (2013) 122 (21): 2791.
https://doi.org/10.1182/blood.V122.21.2791.2791
Published: 2013
Journal Articles

Patient Derived Xenograft (PDX) Models Faithfully Recapitulate The Genetic Composition Of Primary AML

Andrei V. Krivtsov, PhD, Wang Xujun, MD, Noushin Rahnamay Farnoud, PhD, Michael Hadler, MSc, Kristina M. Knapp, BS, Eytan M Stein, MD, Martin S. Tallman, MD, Amy L Donahue, MS, Doron Lipson, PhD, Michelle K. Nahas, PhD, Philip J. Stephens, PhD, Eric M Sanford, BS, Kai Wang, MD PhD, Garrett M Frampton, PhD, Tim Brennan, PhD, Geoff A. Otto, PhD, Roman Yelensky, PhD, Vincent A. Miller, MD, Ross L. Levine, MD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1328.
https://doi.org/10.1182/blood.V122.21.1328.1328
Published: 2013
Journal Articles

Mutational Profiling Of Myeloid Malignancies For Prediction Of Disease Relapse Following Allogeneic Stem Cell Transplantation

Alan M Hanash, MD, PhD, Sean M. Devlin, PhD, Molly Maloy, MA, Kristina M. Knapp, BS, Vincent A. Miller, MD, Doron Lipson, PhD, Philip J. Stephens, PhD, Geoff A Otto, PhD, Roman Yelensky, PhD, Michelle K. Nahas, PhD, Kai Wang, MD PhD, Ross L. Levine, MD, Marcel R.M. van den Brink, MD, PhD, Ann A. Jakubowski, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2096.
https://doi.org/10.1182/blood.V122.21.2096.2096
Published: 2013
Journal Articles

Integrated Genetic Profiling Of JAK2 Wildtype Chronic-Phase Myeloproliferative Neoplasms

Raajit K. Rampal, M.D., Ph.D., Sean M. Devlin, PhD, Jay P. Patel, Kristina M. Knapp, BS, Minal Patel, Joel R Greenbowe, BS, Lauren E Young, MS, Jie He, PhD, Kai Wang, MD PhD, Michelle K. Nahas, PhD, Roman Yelensky, PhD, Geoff A. Otto, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Vincent A. Miller, MD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 1588.
https://doi.org/10.1182/blood.V122.21.1588.1588
Published: 2013
Journal Articles

High-Throughput Mutational Profiling Of Post-Myeloproliferative Neoplasm Acute Myeloid Leukemia Reveals Frequent Mutations In NRAS In JAK2 V617F-Negative Post-MPN AML

Raajit K. Rampal, M.D., Ph.D, Sean M. Devlin, PhD, Anna Sophia Mckenney, B.S. M.P.H., Kristina M. Knapp, BS, Minal Patel, Kai Wang, MD PhD, Michelle K. Nahas, PhD, Roman Yelensky, PhD, Geoff A. Otto, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Vincent A. Miller, MD, Taghi Manshouri, Ph.D., Srdan Verstovsek, MD, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 4098.
https://doi.org/10.1182/blood.V122.21.4098.4098
Published: 2013
Journal Articles

Identification Of Actionable Genomic Alterations In Hematologic Malignancies By a Clinical Next Generation Sequencing-Based Assay

Doron Lipson, PhD, Michelle K Nahas, PhD, Geoff A. Otto, PhD, Roman Yelensky, PhD, Omar Abdel-Wahab, MD, Kai Wang, MD PhD, Jie He, PhD, Andrew M. Intlekofer, MD, PhD, Raajit K. Rampal, M.D., Ph.D., Timothy A Brennan, MS, Kristina M. Knapp, BS, Kristina W Brennan, BS, Geneva Young, BS, Amy L Donahue, MS, Eric M Sanford, BS, Joel R Greenbowe, BS, Garrett M Frampton, PhD, Alex Fichtenholtz, PhD, Lauren E Young, MS, Rachel L Erlich, PhD, Alex Parker, PhD, David Klimstra, Ahmet Dogan, MD, PhD, Jeffrey S Ross, MD, Scott A. Armstrong, MD, PhD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD, PhD, Vincent A. Miller, MD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 230.
https://doi.org/10.1182/blood.V122.21.230.230
Published: 2013