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Kyle MacBeth, PhD
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Journal Articles

Luspatercept Significantly Reduces Red Blood Cell (RBC) Transfusion Burden, Regardless of Gene Mutation Frequency, Spectrum, and Prognostic Significance, Among Patients (Pts) with LR-MDS Enrolled in the MEDALIST Trial

Uwe Platzbecker, Diana Dunshee, Rami S. Komrokji, MD, Ghulam J. Mufti, Guillermo Garcia-Manero, MD, Rena Buckstein, MD FRCPC, Valeria Santini, MD, María Díez-Campelo, MD PhD, Mikkael A. Sekeres, MD MS, Wendy L. See, Kevin Tsai, Alberto Risueño, Jianglin Ma, Martin Schwickart, Anita Rampersad, Jennie Zhang, Abderrahmane Laadem, Daniel Menezes, Kyle MacBeth, PhD, Peter G. Linde, Joseph G. Reynolds, PhD, Alan F. List, MD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2999.
https://doi.org/10.1182/blood-2019-123655
Published: 2019
Journal Articles

Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) with Isocitrate Dehydrogenase 2 ( IDH2 ) Mutations: Interim Phase II Results from an Ongoing, Randomized Study

Courtney D. DiNardo, MD MSc, Andre C. Schuh, MD, Eytan M. Stein, MD, Pau Montesinos Fernandez, MD PhD, Andrew Wei, MBBS, FRACP, FRCPA, PhD, Stephane De Botton, Amer M. Zeidan, MBBS, MHS, Amir T. Fathi, MD, Lynn Quek, MD PhD, Hagop M. Kantarjian, MD, Mark G. Frattini, MD, Frederik Lersch, RN, Jing Gong, PhD, Aleksandra Franovic, PhD, Kyle MacBeth, PhD, Paresh Vyas, MD PhD, Hartmut Döhner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 643.
https://doi.org/10.1182/blood-2019-130362
Published: 2019
Journal Articles

Comprehensive Genomic Analysis of IDH Inhibitor-Treated AML Samples Delineates Molecular Mechanisms of Differentiation and Heterogeneous Patterns of Acquired Resistance

Feng Wang, PhD, Kiyomi Morita, MD, Courtney D. DiNardo, MDMSc, Keyur Patel, MD PhD, Kyle MacBeth, PhD, Alessandra Tosolini, BS, Mark G. Frattini, MD, Jairo Matthews, BA, Latasha Little, Curtis Gumbs, Samantha Tippen, Xingzhi Song, PhD, Jianhua Zhang, PhD, Erika Thompson, MS, Tapan M. Kadia, MD, Guillermo Garcia-Manero, MD, Elias J. Jabbour, MD, Farhad Ravandi, MD, Marina Y. Konopleva, MD PhD, Hagop M. Kantarjian, MD, Andrew Futreal, PhD, Koichi Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 441.
https://doi.org/10.1182/blood-2018-99-116383
Published: 2018
Journal Articles

Combination of Enasidenib and Venetoclax Shows Superior Anti-Leukemic Activity Against IDH2 Mutated AML in Patient-Derived Xenograft Models

Severine Cathelin, PhD, David Sharon, PhD, Amit Subedi, PhD, Dan Cojocari, PhD BSc, Darren C. Phillips, PhD, Joel D. Leverson, PhD, Kyle MacBeth, PhD, Brandon Nicolay, Rohini Narayanaswamy, Sebastien Ronseaux, Guowen Liu, PhD, Steven M Chan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 562.
https://doi.org/10.1182/blood-2018-99-119688
Published: 2018