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Martin Schwickart
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Journal Articles

Luspatercept Redistributes Body Iron to the Liver in Transfusion-Dependent-Thalassemia (TDT) during Erythropoietic Response

Maciej W. Garbowski, Manuel Ugidos, Alberto Risueño, Rajasekhar N.V.S. Suragani, Jeevan K. Shetty, Sadanand Vodala, Anjan Thakurta, Martin Schwickart, John B. Porter
Journal: Blood
Blood (2021) 138 (Supplement 1): 761.
https://doi.org/10.1182/blood-2021-145975
Published: 2021
Journal Articles

Effect of Luspatercept on Biomarkers of Erythropoiesis in Patients (Pts) with Lower-Risk Myelodysplastic Syndromes (LR-MDS) in the Medalist Trial

Uwe Platzbecker, Yiming Zhu, Xianwei Ha, Alberto Risueño, Esther Chan, George Zhang, Diana R. Dunshee, Melih Acar, Jeevan K. Shetty, Rodrigo Ito, Kyle MacBeth, Valeria Santini, Maciej W. Garbowski, Pierre Fenaux, MD PhD, Martin Schwickart
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-136705
Published: 2020
Journal Articles

Duration of Response to Luspatercept in Patients (Pts) Requiring Red Blood Cell (RBC) Transfusions with Myelofibrosis (MF) - Updated Data from the Phase 2 ACE-536-MF-001 Study

Aaron T. Gerds, MDMS, Alessandro M. Vannucchi, MD, Francesco Passamonti, Marina Kremyanskaya, Jason Gotlib, Jeanne M. Palmer, MD, Kelly McCaul, Vincent Ribrag, MD, Adam J. Mead, MD PhD, Claire Harrison, DM, FRCP, FRCPath, Ruben Mesa, MD, Jean-Jacques Kiladjian, Giovanni Barosi, Torsten G. Gerike, Jeevan K. Shetty, Joseph Pariseau, Gabriel Miranda, Martin Schwickart, Ana Carolina Giuseppi, Jennie Zhang, Jay T. Backstrom, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-137265
Published: 2020
Journal Articles

Rapamycin (Sirolimus) and Rap-536 Increase Red Blood Cell Parameters through Distinct Mechanisms in Wild-Type and Thalassemic Mice

Melih Acar, Madhulika Jupelli, Kyle MacBeth, Martin Schwickart
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-137392
Published: 2020
Journal Articles

Rap-536 Induces Reticulocyte Maturation in Wild-Type Mice, Increases Survival of Beta-Thalassemic Reticulocytes, and Increases Red Blood Cells in a Mouse Model of Alpha-Thalassemia

Melih Acar, Madhulika Jupelli, Roberto A. Abbiati, Harish N. Ramanathan, Cristina C. Santini, Alexander Ratushny, Diana R. Dunshee, Daniel Lopes de Menezes, PhD, Kyle MacBeth, Rajasekhar N.V.S. Suragani, Remco Loos, Martin Schwickart
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-137373
Published: 2020
Journal Articles

Luspatercept Significantly Reduces Red Blood Cell (RBC) Transfusion Burden, Regardless of Gene Mutation Frequency, Spectrum, and Prognostic Significance, Among Patients (Pts) with LR-MDS Enrolled in the MEDALIST Trial

Uwe Platzbecker, Diana Dunshee, Rami S. Komrokji, MD, Ghulam J. Mufti, Guillermo Garcia-Manero, MD, Rena Buckstein, MD FRCPC, Valeria Santini, MD, María Díez-Campelo, MD PhD, Mikkael A. Sekeres, MD MS, Wendy L. See, Kevin Tsai, Alberto Risueño, Jianglin Ma, Martin Schwickart, Anita Rampersad, Jennie Zhang, Abderrahmane Laadem, Daniel Menezes, Kyle MacBeth, PhD, Peter G. Linde, Joseph G. Reynolds, PhD, Alan F. List, MD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2999.
https://doi.org/10.1182/blood-2019-123655
Published: 2019
Journal Articles

GDF15 and Erythroferrone Mark Erythropoietic Response to ACE-011 (Sotatercept) in Thalassemia

Maciej W Garbowski, MD PhD, Olivier Hermine, MD PhD, Maria Domenica Cappellini, MD, Raffaella Origa, MD, Gian Luca Forni, MD, Ersi Voskaridou, MD, Frédéric Galactéros, MD PhD, Ali Taher, MD PhD, Jean Benoît Arlet, MD PhD, Jean-Antoine Ribeil, MD PhD, Giovanna Graziadei, MD, Chantal Brouzes, MD, Michaela Semeraro, MD PhD, Patricia Evans, PhD, Abderrahmane Laadem, MD, Dimana Miteva, PhD, Jun Zou, MD PhD, Tatiana Zinger, PhD, Martin Schwickart, PhD, Victoria Sung, PhD, John Porter, MA MD FRCP FRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 3633.
https://doi.org/10.1182/blood-2018-99-111770
Published: 2018